메뉴 건너뛰기




Volumn 51, Issue 1, 2012, Pages 168-180

Vascular tissues are a primary source of BMP2 expression during bone formation induced by distraction osteogenesis

Author keywords

Angiogenesis; Bone morphogenetic protein 2; Distraction osteogenesis; Placental growth factor; Vascular endothelial growth factor

Indexed keywords

BETA GALACTOSIDASE; BONE MORPHOGENETIC PROTEIN 2; MESSENGER RNA; PLACENTAL GROWTH FACTOR; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2;

EID: 84861830833     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2012.02.017     Document Type: Article
Times cited : (116)

References (67)
  • 1
    • 0032990728 scopus 로고    scopus 로고
    • Effect of lengthening rate on angiogenesis during distraction osteogenesis
    • Li G., Simpson A.H., Kenwright J., Triffitt J.T. Effect of lengthening rate on angiogenesis during distraction osteogenesis. J Orthop Res 1999, 17:362-367.
    • (1999) J Orthop Res , vol.17 , pp. 362-367
    • Li, G.1    Simpson, A.H.2    Kenwright, J.3    Triffitt, J.T.4
  • 2
    • 0033027858 scopus 로고    scopus 로고
    • VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation
    • Gerber H.P., Vu T.H., Ryan A.M., Kowalski J., Werb Z., Ferrara N. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med 1999, 5:623-628.
    • (1999) Nat Med , vol.5 , pp. 623-628
    • Gerber, H.P.1    Vu, T.H.2    Ryan, A.M.3    Kowalski, J.4    Werb, Z.5    Ferrara, N.6
  • 4
    • 0028300296 scopus 로고
    • Temporal and spatial increases in blood flow during distraction osteogenesis
    • Aronson J. Temporal and spatial increases in blood flow during distraction osteogenesis. Clin Orthop Relat Res 1994, 301:124-131.
    • (1994) Clin Orthop Relat Res , vol.301 , pp. 124-131
    • Aronson, J.1
  • 5
    • 36549054149 scopus 로고    scopus 로고
    • Assessing angiogenesis during fracture healing
    • Lu C., Marcucio R., Miclau T. Assessing angiogenesis during fracture healing. Iowa Orthop J 2006, 26:17-26.
    • (2006) Iowa Orthop J , vol.26 , pp. 17-26
    • Lu, C.1    Marcucio, R.2    Miclau, T.3
  • 6
    • 20044375180 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha (TNF-alpha) coordinately regulates the expression of specific matrix metalloproteinases (MMPS) and angiogenic factors during fracture healing
    • Lehmann W., Edgar C.M., Wang K., et al. Tumor necrosis factor alpha (TNF-alpha) coordinately regulates the expression of specific matrix metalloproteinases (MMPS) and angiogenic factors during fracture healing. Bone 2005, 36:300-310.
    • (2005) Bone , vol.36 , pp. 300-310
    • Lehmann, W.1    Edgar, C.M.2    Wang, K.3
  • 7
    • 33646411269 scopus 로고    scopus 로고
    • Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair
    • Maes C., Coenegrachts L., Stockmans I., et al. Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair. J Clin Invest 2006, 116:1230-1242.
    • (2006) J Clin Invest , vol.116 , pp. 1230-1242
    • Maes, C.1    Coenegrachts, L.2    Stockmans, I.3
  • 8
    • 0037162547 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
    • Street J., Bao M., de Guzman L., et al. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci U S A 2002, 99:9656-9661.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 9656-9661
    • Street, J.1    Bao, M.2    de Guzman, L.3
  • 9
    • 20844434360 scopus 로고    scopus 로고
    • Angiogenesis is required for successful bone induction during distraction osteogenesis
    • Fang T.D., Salim A., Xia W., et al. Angiogenesis is required for successful bone induction during distraction osteogenesis. J Bone Miner Res 2005, 20:1114-1124.
    • (2005) J Bone Miner Res , vol.20 , pp. 1114-1124
    • Fang, T.D.1    Salim, A.2    Xia, W.3
  • 10
    • 42449132519 scopus 로고    scopus 로고
    • Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling
    • Jacobsen K.A., Al-Aql Z.S., Wan C., et al. Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. J Bone Miner Res 2008, 23:596-609.
    • (2008) J Bone Miner Res , vol.23 , pp. 596-609
    • Jacobsen, K.A.1    Al-Aql, Z.S.2    Wan, C.3
  • 11
    • 27444446737 scopus 로고    scopus 로고
    • VEGF improves, whereas sFlt-1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis
    • Peng H., Usas A., Olshanski A., et al. VEGF improves, whereas sFlt-1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis. J Bone Miner Res 2005, 20:2017-2027.
    • (2005) J Bone Miner Res , vol.20 , pp. 2017-2027
    • Peng, H.1    Usas, A.2    Olshanski, A.3
  • 12
    • 33750050271 scopus 로고    scopus 로고
    • Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification
    • Hirao M., Tamai N., Tsumaki N., Yoshikawa H., Myoui A. Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification. J Biol Chem 2006, 281:31079-31092.
    • (2006) J Biol Chem , vol.281 , pp. 31079-31092
    • Hirao, M.1    Tamai, N.2    Tsumaki, N.3    Yoshikawa, H.4    Myoui, A.5
  • 13
    • 78651226925 scopus 로고    scopus 로고
    • Lack of HIF-2α in limb bud mesenchyme causes a modest and transient delay of endochondral bone development
    • Araldi E., Khatri R., Giaccia A.J., Simon M.C., Schipani E. Lack of HIF-2α in limb bud mesenchyme causes a modest and transient delay of endochondral bone development. Nat Med 2011, 17:25-26.
    • (2011) Nat Med , vol.17 , pp. 25-26
    • Araldi, E.1    Khatri, R.2    Giaccia, A.J.3    Simon, M.C.4    Schipani, E.5
  • 14
    • 77953499330 scopus 로고    scopus 로고
    • Vessel formation is induced prior to the appearance of cartilage in BMP2-mediated heterotopic ossification
    • Dilling C.F., Wada A., Lazard Z., et al. Vessel formation is induced prior to the appearance of cartilage in BMP2-mediated heterotopic ossification. J Bone Miner Res 2010, 25:1147-1156.
    • (2010) J Bone Miner Res , vol.25 , pp. 1147-1156
    • Dilling, C.F.1    Wada, A.2    Lazard, Z.3
  • 15
    • 67650733297 scopus 로고    scopus 로고
    • The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf
    • Eshkar-Oren I., Viukov S.V., Salameh S., et al. The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf. Development 2009, 136:1263-1272.
    • (2009) Development , vol.136 , pp. 1263-1272
    • Eshkar-Oren, I.1    Viukov, S.V.2    Salameh, S.3
  • 16
    • 33751506452 scopus 로고    scopus 로고
    • BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
    • Tsuji K., Bandyopadhyay A., Harfe B.D., et al. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet 2006, 38:1424-1429.
    • (2006) Nat Genet , vol.38 , pp. 1424-1429
    • Tsuji, K.1    Bandyopadhyay, A.2    Harfe, B.D.3
  • 17
    • 67649444317 scopus 로고    scopus 로고
    • BMP2 is essential for post natal osteogenesis but not for recruitment of osteogenic stem cells
    • Bais M.V., Wigner N., Young M., et al. BMP2 is essential for post natal osteogenesis but not for recruitment of osteogenic stem cells. Bone 2009, 45:254-266.
    • (2009) Bone , vol.45 , pp. 254-266
    • Bais, M.V.1    Wigner, N.2    Young, M.3
  • 18
    • 34047267341 scopus 로고    scopus 로고
    • Autogenous regulation of a network of bone morphogenetic proteins (BMPs) mediates the osteogenic differentiation in murine marrow stromal cells
    • Edgar C.M., Chakravarthy V., Barnes G., et al. Autogenous regulation of a network of bone morphogenetic proteins (BMPs) mediates the osteogenic differentiation in murine marrow stromal cells. Bone 2007, 40:1389-1398.
    • (2007) Bone , vol.40 , pp. 1389-1398
    • Edgar, C.M.1    Chakravarthy, V.2    Barnes, G.3
  • 19
    • 0029008655 scopus 로고
    • Immunolocalization and local expression of bone morphogenetic proteins 2 and 4 in fracture healing
    • Bostrom M.P., Lane J.M., Berberian W.S., et al. Immunolocalization and local expression of bone morphogenetic proteins 2 and 4 in fracture healing. J Orthop Res 1995, 13:357-367.
    • (1995) J Orthop Res , vol.13 , pp. 357-367
    • Bostrom, M.P.1    Lane, J.M.2    Berberian, W.S.3
  • 20
    • 77649187986 scopus 로고    scopus 로고
    • Immunolocalization of BMPs, BMP antagonists, receptors, and effectors during fracture repair
    • Yu Y.Y., Lieu S., Lu C., Miclau T., Marcucio R.S., Colnot C. Immunolocalization of BMPs, BMP antagonists, receptors, and effectors during fracture repair. Bone 2010, 46:841-851.
    • (2010) Bone , vol.46 , pp. 841-851
    • Yu, Y.Y.1    Lieu, S.2    Lu, C.3    Miclau, T.4    Marcucio, R.S.5    Colnot, C.6
  • 21
    • 4644233271 scopus 로고    scopus 로고
    • Protein-based tissue engineering in bone and cartilage repair
    • Wozney J.M., Seeherman H.J. Protein-based tissue engineering in bone and cartilage repair. Curr Opin Biotechnol 2004, 15:392-398.
    • (2004) Curr Opin Biotechnol , vol.15 , pp. 392-398
    • Wozney, J.M.1    Seeherman, H.J.2
  • 22
    • 3543145020 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 stimulates angiogenesis in developing tumors
    • Langenfeld E.M., Langenfeld J. Bone morphogenetic protein-2 stimulates angiogenesis in developing tumors. Mol Cancer Res 2004, 2:141-149.
    • (2004) Mol Cancer Res , vol.2 , pp. 141-149
    • Langenfeld, E.M.1    Langenfeld, J.2
  • 23
    • 27644508801 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis
    • Raida M., Clement J.H., Leek R.D., et al. Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis. J Cancer Res Clin Oncol 2005, 131:741-750.
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 741-750
    • Raida, M.1    Clement, J.H.2    Leek, R.D.3
  • 25
    • 78651341882 scopus 로고    scopus 로고
    • BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways
    • Perez V.A., Ali Z., Alastalo T.P., et al. BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways. J Cell Biol 2011, 192:171-188.
    • (2011) J Cell Biol , vol.192 , pp. 171-188
    • Perez, V.A.1    Ali, Z.2    Alastalo, T.P.3
  • 26
    • 33644865928 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension
    • Teichert-Kuliszewska K., Kutryk M.J., Kuliszewski M.A., et al. Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension. Circ Res 2006, 98:209-217.
    • (2006) Circ Res , vol.98 , pp. 209-217
    • Teichert-Kuliszewska, K.1    Kutryk, M.J.2    Kuliszewski, M.A.3
  • 27
    • 42949178711 scopus 로고    scopus 로고
    • Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells
    • Yu P.B., Deng D.Y., Beppu H., et al. Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth arrest and differentiation in pulmonary artery smooth muscle cells. J Biol Chem 2008, 283:3877-3888.
    • (2008) J Biol Chem , vol.283 , pp. 3877-3888
    • Yu, P.B.1    Deng, D.Y.2    Beppu, H.3
  • 28
    • 80055024008 scopus 로고    scopus 로고
    • The transcriptome of fracture healing defines mechanisms of coordination of skeletal and vascular development during endochondral bone formation
    • Grimes R., Jepsen K.J., Fitch J.L., Einhorn T.A., Gerstenfeld L.C. The transcriptome of fracture healing defines mechanisms of coordination of skeletal and vascular development during endochondral bone formation. J Bone Miner Res 2011, 26(11):2597-2609.
    • (2011) J Bone Miner Res , vol.26 , Issue.11 , pp. 2597-2609
    • Grimes, R.1    Jepsen, K.J.2    Fitch, J.L.3    Einhorn, T.A.4    Gerstenfeld, L.C.5
  • 29
    • 59849099675 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt beta-catenin and Wnt-RhoA-Rac1 pathways
    • de Jesus Perez V.A., Alastalo T.P., Wu J.C., et al. Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt beta-catenin and Wnt-RhoA-Rac1 pathways. J Cell Biol 2009, 184:83-99.
    • (2009) J Cell Biol , vol.184 , pp. 83-99
    • de Jesus Perez, V.A.1    Alastalo, T.P.2    Wu, J.C.3
  • 30
    • 0242443189 scopus 로고    scopus 로고
    • Matrix GLA protein and BMP-2 regulate osteoinduction in calcifying vascular cells
    • Zebboudj A.F., Shin V., Boström K. Matrix GLA protein and BMP-2 regulate osteoinduction in calcifying vascular cells. J Cell Biochem 2003, 90:756-765.
    • (2003) J Cell Biochem , vol.90 , pp. 756-765
    • Zebboudj, A.F.1    Shin, V.2    Boström, K.3
  • 31
    • 2942726266 scopus 로고    scopus 로고
    • Regulatory role of endothelium in the expression of genes affecting arterial calcification
    • Cola C., Almeida M., Li D., Romeo F., Mehta J.L. Regulatory role of endothelium in the expression of genes affecting arterial calcification. Biochem Biophys Res Commun 2004, 320:424-427.
    • (2004) Biochem Biophys Res Commun , vol.320 , pp. 424-427
    • Cola, C.1    Almeida, M.2    Li, D.3    Romeo, F.4    Mehta, J.L.5
  • 32
    • 34347388823 scopus 로고    scopus 로고
    • Role of bone morphogenetic protein 2 in the crosstalk between endothelial progenitor cells and mesenchymal stem cells
    • Raida M., Heymann A.C., Gunther C., Niederwieser D. Role of bone morphogenetic protein 2 in the crosstalk between endothelial progenitor cells and mesenchymal stem cells. Int J Mol Med 2006, 18:735-739.
    • (2006) Int J Mol Med , vol.18 , pp. 735-739
    • Raida, M.1    Heymann, A.C.2    Gunther, C.3    Niederwieser, D.4
  • 33
    • 34147205885 scopus 로고    scopus 로고
    • BMP2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter
    • Chandler R.L., Chandler K.J., McFarland K.A., Mortlock D.P. BMP2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter. Mol Cell Biol 2007, 27:2934-2951.
    • (2007) Mol Cell Biol , vol.27 , pp. 2934-2951
    • Chandler, R.L.1    Chandler, K.J.2    McFarland, K.A.3    Mortlock, D.P.4
  • 34
    • 0141519291 scopus 로고    scopus 로고
    • A general approach for identifying distant regulatory elements applied to the Gdf6 gene
    • Mortlock D.P., Guenther C., Kingsley D.M. A general approach for identifying distant regulatory elements applied to the Gdf6 gene. Genome Res 2003, 13:2069-2081.
    • (2003) Genome Res , vol.13 , pp. 2069-2081
    • Mortlock, D.P.1    Guenther, C.2    Kingsley, D.M.3
  • 35
    • 80052633277 scopus 로고    scopus 로고
    • Conserved signaling through vascular endothelial growth (VEGF) receptor family members in murine lymphatic endothelial cells
    • Coso S., Zeng Y., Sooraj D., Williams E.D. Conserved signaling through vascular endothelial growth (VEGF) receptor family members in murine lymphatic endothelial cells. Exp Cell Res 2011, 317(17):2397-2407.
    • (2011) Exp Cell Res , vol.317 , Issue.17 , pp. 2397-2407
    • Coso, S.1    Zeng, Y.2    Sooraj, D.3    Williams, E.D.4
  • 36
    • 33644925814 scopus 로고    scopus 로고
    • VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells
    • Alva J.A., Zovein A.C., Monvoisin A., Murphy T., Salazar A., Harvey N.L., et al. VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells. Dev Dyn 2006, 235(3):759-767.
    • (2006) Dev Dyn , vol.235 , Issue.3 , pp. 759-767
    • Alva, J.A.1    Zovein, A.C.2    Monvoisin, A.3    Murphy, T.4    Salazar, A.5    Harvey, N.L.6
  • 37
    • 47249146982 scopus 로고    scopus 로고
    • Role of ephrinB2 expression in endothelial cells during arteriogenesis: impact on smooth muscle cell migration and monocyte recruitment
    • Korff T., Braun J., Pfaff D., Augustin H.G., Hecker M. Role of ephrinB2 expression in endothelial cells during arteriogenesis: impact on smooth muscle cell migration and monocyte recruitment. Blood 2008, 112(1):73-81.
    • (2008) Blood , vol.112 , Issue.1 , pp. 73-81
    • Korff, T.1    Braun, J.2    Pfaff, D.3    Augustin, H.G.4    Hecker, M.5
  • 39
    • 54249131123 scopus 로고    scopus 로고
    • VEGF enhancement of osteoclast survival and bone resorption involves VEGF receptor-2 signaling and beta3-integrin
    • Yang Q., McHugh K.P., Patntirapong S., Gu X., Wunderlich L., Hauschka P.V. VEGF enhancement of osteoclast survival and bone resorption involves VEGF receptor-2 signaling and beta3-integrin. Matrix Biol 2008, 27:589-599.
    • (2008) Matrix Biol , vol.27 , pp. 589-599
    • Yang, Q.1    McHugh, K.P.2    Patntirapong, S.3    Gu, X.4    Wunderlich, L.5    Hauschka, P.V.6
  • 40
    • 77953407742 scopus 로고    scopus 로고
    • Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis
    • Kramer I., Halleux C., Keller H., Pegurri M., Gooi J.H., Weber P.B., et al. Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis. Mol Cell Biol 2010, 30:3071-3085.
    • (2010) Mol Cell Biol , vol.30 , pp. 3071-3085
    • Kramer, I.1    Halleux, C.2    Keller, H.3    Pegurri, M.4    Gooi, J.H.5    Weber, P.B.6
  • 41
    • 0036105935 scopus 로고    scopus 로고
    • Hypoxia and VEGF up-regulate BMP-2 mRNA and protein expression in microvascular endothelial cells: implications for fracture healing
    • Bouletreau P.J., Warren S.M., Spector J.A., et al. Hypoxia and VEGF up-regulate BMP-2 mRNA and protein expression in microvascular endothelial cells: implications for fracture healing. Plast Reconstr Surg 2002, 109:2384-2397.
    • (2002) Plast Reconstr Surg , vol.109 , pp. 2384-2397
    • Bouletreau, P.J.1    Warren, S.M.2    Spector, J.A.3
  • 42
    • 67449146883 scopus 로고    scopus 로고
    • Emerging role of bone morphogenetic proteins in angiogenesis
    • David L., Feige J.J., Bailly S. Emerging role of bone morphogenetic proteins in angiogenesis. Cytokine Growth Factor Rev 2009, 20:203-212.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 203-212
    • David, L.1    Feige, J.J.2    Bailly, S.3
  • 43
    • 8644256840 scopus 로고    scopus 로고
    • BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia
    • Beppu H., Ichinose F., Kawai N., et al. BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia. Am J Physiol Lung Cell Mol Physiol 2004, 287:1241-1247.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287 , pp. 1241-1247
    • Beppu, H.1    Ichinose, F.2    Kawai, N.3
  • 44
    • 45149132191 scopus 로고    scopus 로고
    • Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension
    • Yang J., Davies R.J., Southwood M., et al. Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension. Circ Res 2008, 102:1212-1221.
    • (2008) Circ Res , vol.102 , pp. 1212-1221
    • Yang, J.1    Davies, R.J.2    Southwood, M.3
  • 45
    • 34548853386 scopus 로고    scopus 로고
    • Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity
    • Liu D., Wang J., Kinzel B., et al. Dosage-dependent requirement of BMP type II receptor for maintenance of vascular integrity. Blood 2007, 110:1502-1510.
    • (2007) Blood , vol.110 , pp. 1502-1510
    • Liu, D.1    Wang, J.2    Kinzel, B.3
  • 46
    • 33646348736 scopus 로고    scopus 로고
    • A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic Fibrodysplasia Ossificans Progressiva
    • Shore E.M., Xu M., Feldman G.J., et al. A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic Fibrodysplasia Ossificans Progressiva. Nat Genet 2006, 38(5):525-527.
    • (2006) Nat Genet , vol.38 , Issue.5 , pp. 525-527
    • Shore, E.M.1    Xu, M.2    Feldman, G.J.3
  • 47
    • 78650018824 scopus 로고    scopus 로고
    • Conversion of vascular endothelial cells into multipotent stem-like cells
    • Medici D., Shore E.M., Lounev V.Y., Kaplan F.S., Kalluri R., Olsen B.R. Conversion of vascular endothelial cells into multipotent stem-like cells. Nat Med 2010, 16(12):1400-1406.
    • (2010) Nat Med , vol.16 , Issue.12 , pp. 1400-1406
    • Medici, D.1    Shore, E.M.2    Lounev, V.Y.3    Kaplan, F.S.4    Kalluri, R.5    Olsen, B.R.6
  • 48
    • 40949158527 scopus 로고    scopus 로고
    • BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells
    • Li X., Yang H.Y., Giachelli C.M. BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells. Atherosclerosis 2008, 199:271-277.
    • (2008) Atherosclerosis , vol.199 , pp. 271-277
    • Li, X.1    Yang, H.Y.2    Giachelli, C.M.3
  • 49
    • 77957708681 scopus 로고    scopus 로고
    • Paracrine osteogenic signals via bone morphogenetic protein-2 accelerate the atherosclerotic intimal calcification in vivo
    • Nakagawa Y., Ikeda K., Akakabe Y., et al. Paracrine osteogenic signals via bone morphogenetic protein-2 accelerate the atherosclerotic intimal calcification in vivo. Arterioscler Thromb Vasc Biol 2010, 10:1908-1915.
    • (2010) Arterioscler Thromb Vasc Biol , vol.10 , pp. 1908-1915
    • Nakagawa, Y.1    Ikeda, K.2    Akakabe, Y.3
  • 50
    • 59149096379 scopus 로고    scopus 로고
    • BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
    • Kamiya N., Ye L., Kobayashi T., et al. BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development 2008, 135:3801-3811.
    • (2008) Development , vol.135 , pp. 3801-3811
    • Kamiya, N.1    Ye, L.2    Kobayashi, T.3
  • 51
    • 33750973380 scopus 로고    scopus 로고
    • Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling
    • Goodwin A.M., Sullivan K.M., D'Amore P.A. Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling. Dev Dyn 2006, 235:3110-3120.
    • (2006) Dev Dyn , vol.235 , pp. 3110-3120
    • Goodwin, A.M.1    Sullivan, K.M.2    D'Amore, P.A.3
  • 52
    • 78650419119 scopus 로고    scopus 로고
    • The Wnt antagonist Dickkopf-1 increases endothelial progenitor cell angiogenic potential
    • Smadja D.M., d'Audigier C., Weiswald L.B., et al. The Wnt antagonist Dickkopf-1 increases endothelial progenitor cell angiogenic potential. Arterioscler Thromb Vasc Biol 2010, 30:2544-2552.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 2544-2552
    • Smadja, D.M.1    d'Audigier, C.2    Weiswald, L.B.3
  • 53
    • 39649099580 scopus 로고    scopus 로고
    • The Dickkopf-homolog 3 is expressed in tumor endothelial cells and supports capillary formation
    • Untergasser G., Steurer M., Zimmermann M., et al. The Dickkopf-homolog 3 is expressed in tumor endothelial cells and supports capillary formation. Int J Cancer 2008, 122(7):1539-1547.
    • (2008) Int J Cancer , vol.122 , Issue.7 , pp. 1539-1547
    • Untergasser, G.1    Steurer, M.2    Zimmermann, M.3
  • 54
    • 33846925672 scopus 로고    scopus 로고
    • SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development
    • van Bezooijen R.L., Deruiter M.C., Vilain N., et al. SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development. Dev Dyn 2007, 236(2):606-612.
    • (2007) Dev Dyn , vol.236 , Issue.2 , pp. 606-612
    • van Bezooijen, R.L.1    Deruiter, M.C.2    Vilain, N.3
  • 55
    • 77954346513 scopus 로고    scopus 로고
    • Inhibition of canonical Wnt signaling increases microvascular hemorrhaging and venular remodeling in adult rats
    • Glaw J.T., Skalak T.C., Peirce S.M. Inhibition of canonical Wnt signaling increases microvascular hemorrhaging and venular remodeling in adult rats. Microcirculation 2010, 17(5):348-357.
    • (2010) Microcirculation , vol.17 , Issue.5 , pp. 348-357
    • Glaw, J.T.1    Skalak, T.C.2    Peirce, S.M.3
  • 56
    • 79954637641 scopus 로고    scopus 로고
    • Sclerostin is a locally acting regulator of late-osteoblast/pre-osteocyte differentiation and regulates mineralization through a MEPE-ASARM dependent mechanism
    • Atkins G.J., Rowe P.S., Lim H.P., et al. Sclerostin is a locally acting regulator of late-osteoblast/pre-osteocyte differentiation and regulates mineralization through a MEPE-ASARM dependent mechanism. J Bone Miner Res 2011, 26(7):1425-1436.
    • (2011) J Bone Miner Res , vol.26 , Issue.7 , pp. 1425-1436
    • Atkins, G.J.1    Rowe, P.S.2    Lim, H.P.3
  • 57
    • 77953381255 scopus 로고    scopus 로고
    • Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts
    • Kamiya N., Kobayashi T., Mochida Y., et al. Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. J Bone Miner Res 2010, 25(2):200-210.
    • (2010) J Bone Miner Res , vol.25 , Issue.2 , pp. 200-210
    • Kamiya, N.1    Kobayashi, T.2    Mochida, Y.3
  • 58
    • 77951242575 scopus 로고    scopus 로고
    • Hypoxia induces BMP-2 expression via ILK, Akt, mTOR, and HIF-1 pathways in osteoblasts
    • Tseng W.P., Yang S.N., Lai C.H. Hypoxia induces BMP-2 expression via ILK, Akt, mTOR, and HIF-1 pathways in osteoblasts. J Cell Physiol 2010, 223:810-818.
    • (2010) J Cell Physiol , vol.223 , pp. 810-818
    • Tseng, W.P.1    Yang, S.N.2    Lai, C.H.3
  • 59
    • 33750339707 scopus 로고    scopus 로고
    • Three-dimensional reconstruction of fracture callus morphogenesis
    • Gerstenfeld L.C., Alkhiary Y.M., Krall E.A., et al. Three-dimensional reconstruction of fracture callus morphogenesis. J Histochem Cytochem 2006, 54:1215-1228.
    • (2006) J Histochem Cytochem , vol.54 , pp. 1215-1228
    • Gerstenfeld, L.C.1    Alkhiary, Y.M.2    Krall, E.A.3
  • 60
    • 2342506584 scopus 로고    scopus 로고
    • The role of angiogenesis in a murine tibial model of distraction osteogenesis
    • Carvalho R.S., Einhorn T.A., Lehmann W., et al. The role of angiogenesis in a murine tibial model of distraction osteogenesis. Bone 2004, 34:849-861.
    • (2004) Bone , vol.34 , pp. 849-861
    • Carvalho, R.S.1    Einhorn, T.A.2    Lehmann, W.3
  • 61
    • 33847228398 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptors after mandibular distraction osteogenesis
    • Byun J.H., Park B.W., Kim J.R., Lee J.H. Expression of vascular endothelial growth factor and its receptors after mandibular distraction osteogenesis. Int J Oral Maxillofac Surg 2007, 36:338-344.
    • (2007) Int J Oral Maxillofac Surg , vol.36 , pp. 338-344
    • Byun, J.H.1    Park, B.W.2    Kim, J.R.3    Lee, J.H.4
  • 62
    • 0027745824 scopus 로고
    • A heparin-binding form of placenta growth factor (PlGF-2) is expressed in human umbilical vein endothelial cells and in placenta
    • Hauser S., Weich H.A. A heparin-binding form of placenta growth factor (PlGF-2) is expressed in human umbilical vein endothelial cells and in placenta. Growth Factors 1993, 9:259-268.
    • (1993) Growth Factors , vol.9 , pp. 259-268
    • Hauser, S.1    Weich, H.A.2
  • 63
    • 0036344496 scopus 로고    scopus 로고
    • Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment
    • Hattori K., Heissig B., Wu Y., et al. Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment. Nat Med 2002, 8:841-849.
    • (2002) Nat Med , vol.8 , pp. 841-849
    • Hattori, K.1    Heissig, B.2    Wu, Y.3
  • 64
    • 0042333448 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 induces placental growth factor in mesenchymal stem cells
    • Marrony S., Bassilana F., Seuwen K., Keller H. Bone morphogenetic protein 2 induces placental growth factor in mesenchymal stem cells. Bone 2003, 33:426-433.
    • (2003) Bone , vol.33 , pp. 426-433
    • Marrony, S.1    Bassilana, F.2    Seuwen, K.3    Keller, H.4
  • 65
    • 0035895771 scopus 로고    scopus 로고
    • Revascularization in the rabbit hindlimb: dissociation between capillary sprouting and arteriogenesis
    • Hershey J.C., Baskin E.P., Glass J.D., et al. Revascularization in the rabbit hindlimb: dissociation between capillary sprouting and arteriogenesis. Cardiovasc Res 2001, 49:618-625.
    • (2001) Cardiovasc Res , vol.49 , pp. 618-625
    • Hershey, J.C.1    Baskin, E.P.2    Glass, J.D.3
  • 66
    • 34250370123 scopus 로고    scopus 로고
    • Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting
    • Wirzenius M., Tammela T., Uutela M., et al. Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting. J Exp Med 2007, 204:1431-1440.
    • (2007) J Exp Med , vol.204 , pp. 1431-1440
    • Wirzenius, M.1    Tammela, T.2    Uutela, M.3
  • 67
    • 77955510391 scopus 로고    scopus 로고
    • VEGF-mediated signal transduction in lymphatic endothelial cells
    • Bahram F., Claesson-Welsh L. VEGF-mediated signal transduction in lymphatic endothelial cells. Pathophysiology 2010, 17:253-261.
    • (2010) Pathophysiology , vol.17 , pp. 253-261
    • Bahram, F.1    Claesson-Welsh, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.