Palytoxin and an Ostreopsis toxin extract increase the levels of mRNAs encoding inflammation-related proteins in human macrophages via p38 MAPK and NF-κB

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Crinelli, Rita ^a   Carloni, Elisa ^a   Giacomini, Elisa ^a   Penna, Antonella ^a   Dominici, Sabrina ^a   Battocchi, Cecilia ^a   Ciminiello, Patrizia ^b   Dell'Aversano, Carmela ^b   Fattorusso, Ernesto ^b   Forino, Martino ^b   Tartaglione, Luciana ^b   Magnani, Mauro ^a  

^a UNIVERSITY OF URBINO   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL PRODUCT; OSTREOPSIS CF OVATA TOXIN EXTRACT; OVATOXIN; PALYTOXIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ACRYLAMIDE DERIVATIVE; MARINE TOXIN; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PEPTIDE HYDROLASE; PTGS2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR RELA;

ALGAL CELL CULTURE; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DINOFLAGELLATE; ELECTROPHORETIC MOBILITY; INFLAMMATION; MACROPHAGE; NONHUMAN; OSTREOPSIS; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRAIN IDENTIFICATION; TOXIN ANALYSIS; TRANSCRIPTION INITIATION; WESTERN BLOTTING; CELL NUCLEUS; CELL SHAPE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG MIXTURE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LIQUID CHROMATOGRAPHY; LYSOSOME; MASS SPECTROMETRY; METABOLISM; MONOCYTE; PROTEIN DEGRADATION; PROTEIN TRANSPORT;

ANIMALIA; DINOPHYCEAE; OSTREOPSIS; OSTREOPSIS OVATA;

ACRYLAMIDES; CELL NUCLEUS; CELL SHAPE; CELL SURVIVAL; CHROMATOGRAPHY, LIQUID; COMPLEX MIXTURES; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B PROTEINS; INFLAMMATION; INTERLEUKIN-8; LYSOSOMES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MARINE TOXINS; MASS SPECTROMETRY; MONOCYTES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE HYDROLASES; PROTEIN TRANSPORT; PROTEOLYSIS; RNA, MESSENGER; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84861752339     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038139     Document Type: Article

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