Effects of the marine toxin palytoxin on human skin keratinocytes: Role of ionic imbalance

Toxicology

Volumn 282, Issue 1-2, 2011, Pages 30-38

  Pelin, M ^a   Zanette, C ^a   De Bortoli, M ^a   Sosa, S ^a   Loggia, R Della ^a   Tubaro, A ^a   Florio, C ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

Cutaneous toxicity; Cytotoxicity; Human HaCaT keratinocytes; Mitochondrial dysfunction; Palytoxin; ROS

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM ION; OUABAIN; PALYTOXIN; SODIUM ION; SUPEROXIDE;

ARTICLE; CELL ACTIVITY; CELL DEATH; CELL FUNCTION; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; MITOCHONDRION; OXIDATIVE STRESS; PRIORITY JOURNAL; SKIN TOXICITY; SODIUM CELL LEVEL;

ACRYLAMIDES; CALCIUM; CALCIUM SIGNALING; CELL DEATH; CELL LINE; CELL MEMBRANE; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; KERATINOCYTES; MARINE TOXINS; MITOCHONDRIA; OXIDATIVE STRESS; SODIUM; SODIUM-POTASSIUM-EXCHANGING ATPASE; SUPEROXIDES; TIME FACTORS;

ANTHOZOA; DINOPHYCEAE; OSTREOPSIS; OSTREOPSIS OVATA; PALYTHOA; STROPHANTHUS GRATUS; ZOANTHIDAE;

EID: 79951575702     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2011.01.010     Document Type: Article

References (41)

1. Ares I.R., Louzao M.C., Vieytes M.R., Yasumoto T., Botana L.M. Actin cytoskeleton of rabbit intestinal cells is a target for potent marine phycotoxins. J. Exp. Biol. 2005, 208:4345-4354.
2. Attaway D.H., Ciereszko L.S. Isolation and partial characterization of Caribbean palytoxin. Proceedings of Second International Coral Reef Symposium I Great Barrier Reef Community 1974.
3. Bellocci M., Ronzitti G., Milandri A., Melchiorre N., Grillo C., Poletti R., Yasumoto T., Rossini G.P. A cytolytic assay for the measurement of palytoxin based on a cultured monolayer cell line. Anal. Biochem. 2008, 374(1):48-55.
4. Beress L., Zwick J., Kolkenbrock H.J., Kaul P.N., Wasserrmann O. A method for the isolation of the Carribean palytoxin (c-PTX) from the coelenterate (zoanthid) Palythoa caribaeorum. Toxicon 1983, 21:285-290.
5. Boukamp P., Petrussevska R.T., Breitkreutz D., Hornung J., Markham A., Fusenig N.E. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol. 1988, 106:761-771.
6. Cañete E., Diogène J. Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins. Toxicon 2008, 52(4):541-550.
7. Ciminiello P., Dell'Aversano C., Fattorusso E., Forino M., Magno G.S., Tartaglione L., Grillo C., Melchiorre N. The Genoa 2005 outbreak. Determination of putative palytoxin in Mediterranean Ostreopsis ovata by a new liquid chromatography tandem mass spectrometry method. Anal. Chem. 2006, 78(17):6153-6159.
8. Ciminiello P., Dell'Aversano C., Fattorusso E., Forino M., Tartaglione L., Grillo C., Melchiorre N. Putative palytoxin and its new analogue, ovatoxin-a, in Ostreopsis ovata collected along the Ligurian coasts during the 2006 toxic outbreak. J. Am. Soc. Mass Spectrom. 2008, 19(1):111-120.
9. Ciminiello P., Dell'Aversano C., Dello Iacovo E., Fattorusso E., Forino M., Grauso L., Tartaglione L., Guerrini F., Pistocchi R. Complex palytoxin-like profile of Ostreopsis ovata. Identification of four new ovatoxins by high-resolution liquid chromatography/mass spectrometry. Rapid Commun. Mass Spectrom. 2010, 24(18):2735-2744.
10. Deeds J.R., Schwartz M.D. Human risk associated with palytoxin exposure. Toxicon 2010, 56(2):150-162.
11. Dubois J.M., Cohen J.B. Effect of palytoxin on membrane and potential and current of frog myelinated fibers. J. Pharmacol. Exp. Ther. 1977, 201(1):145-148.
12. Durando P., Ansaldi F., Oreste P., Moscatelli P., Marensi L., Grillo C., Gasparini R., Icardi G. Ostreopsis ovata and human health: epidemiological and clinical features if respiratory syndrome outbreaks from a two-years sindromi surveillance, 2005-06, in north-west Italy. Euro. Surveill. 2007, 12(6):E070607.1.
13. Fujiki H., Suganuma M., Nakayasu M., Hakii H., Horiuchi T., Takayama S., Sugimura T. Palytoxin is a non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter in two-stage mouse skin carcinogenesis. Carcinogenesis 1986, 7(5):707-710.
14. Gabrielson E.W., Kuppusamy P., Povey A.C., Zweier J.L., Harris C.C. Measurement of neutrophil activation and epidermal cell toxicity by palytoxin and 12-O-tetradecanoylphorbol-13-acetate. Carcinogenesis 1992, 13(9):1671-1674.
15. Gallitelli M., Ungaro M., Addante L.M., Gentiloni Silver M., Sabbà C. Respiratory illness as a reaction to tropical algal blooms occurring in a temperate climate. JAMA 2005, 293:2599-2600.
16. Goldman R., Moshonov S., Zor U. Generation of reactive oxygen species in a human keratinocyte cell line: role of calcium. Arch. Biochem. Biophys. 1998, 350(1):10-18.
17. Gibbs S. In vitro irritation models and immune reactions. Skin Pharmacol. Physiol. 2009, 22(2):103-113.
18. Guerrini F., Pezzolesi L., Feller A., Riccardi M., Ciminiello P., Dell'Aversano C., Tartaglione L., Dello Iacovo E., Fattorusso E., Forino M., Pistocchi R. Comparative growth and toxin profile of cultured Ostreopsis ovata from the Tyrrhenian and Adriatic Seas. Toxicon 2010, 55(2-3):211-220.
19. Habermann E., Chhatwal G.S. Ouabain inhibits the increase due to palytoxin of cation permeability of erythrocytes. Naunyn Schmiedebergs Arch. Pharmacol. 1982, 319(2):101-107.
20. Hoffmann K., Hermanns-Clausen M., Buhl C., Büchler M.W., Schemmer P., Mebs D., Kauferstein S. A case of palytoxin poisoning due to contact with zoanthid corals through a skin injury. Toxicon 2008, 51(8):1535-1537.
21. Ito K., Karaki H., Ishida Y., Urakawa N., Deguchi T. Effects of palytoxin on isolated intestinal and vascular smooth muscle. Jpn. J. Pharmacol. 1976, 26:683-692.
22. Kano S., Iizuka T., Ishimura Y., Fujiki H., Sugimura T. Stimulation of superoxide anion formation by the non-TPA type tumor promoters palytoxin and thapsigargin in porcine and human neutrophils. Biochem. Biophys. Res. Commun. 1987, 143(2):672-677.
23. Kermarec F., Dor F., Armengaud A., Charlet F., Kantin R., Sauzade D., de Haro L. Health risks related to Ostreopsis ovata in recreational waters. Env. Risques Santé 2008, 7(5):357-363.
24. Kimura S., Hashimoto K. Purification of the toxin in a zoanthid Palythoa tuberculosa. Publ. Seto Mar. Biol. Lab. 1973, 20:713-718.
25. Ledreux A., Krys S., Bernard C. Suitability of the Neuro-2a cell line for the detection of palytoxin and analogues (neurotoxic phycotoxins). Toxicon 2009, 53(2):300-308.
26. Lenoir S., Ten-Hage L., Turquet J., Quod J.P., Bernard C., Hennion M.C. First evidence of palytoxin analogs from an Ostreopsis mascarensis (Dinophyceae) benthic bloom in Southwestern Indian Ocean. J. Phycol. 2004, 40:1042-1051.
27. Moore R.E., Scheuer P.J. Palytoxin: a new marine toxin from a coelenterate. Science 1971, 172(982):495-498.
28. Munday R. Occurrence and toxicology of palytoxin. Seafood and Freshwater Toxins. Pharmacology, Physiology and Detection 2008, 693-713. CRC Press, Boca Raton. L.M. Botana (Ed.).
29. Muramatsu I., Uemura D., Fujiwara M., Narahashi T. Characteristics of palytoxin-induced depolarization in squid axons. J. Pharmacol. Exp. Ther. 1984, 231(3):488-494.
30. Nordt S.P., Wu J., Zahller S., Clark R.F., Cantrell F.L. Palytoxin poisoning after dermal contact with zoanthid coral. J. Emerg. Med. 2009, 10.1016/j.jemermed.2009.05.004.
31. Rossi R., Castellano V., Scalco E., Serpe L., Zingone A., Soprano V. New palytoxin-like molecules in Mediterranean Ostreopsis cf. ovata (dinoflagellates) and in Palythoa tuberculosa detected by liquid chromatography-electrospray ionization time-of-flight mass spectrometry. Toxicon 2010, 56(8):1381-1387.
32. Rossini G.P., Bigiani A. Palytoxin action on the Na(+),K(+)-ATPase and the disruption of ion equilibria in biological systems. Toxicon 2010, 10.1016/j.toxicon.2010.09.011.
33. Satoh E., Nakazato Y. Mode of action of palytoxin on the release of acetylcholine from rat cerebrocortical synaptosomes. J. Neurochem. 1991, 57:1276-1280.
34. Schilling W.P., Snyder D., Sinkins W.G., Estacion M. Palytoxin-induced cell death cascade in bovine aortic endothelial cells. Am. J. Physiol. Cell Physiol. 2006, 291(4):C657-C667.
35. Sheridan R.E., Desphande S.S., Adler M. Cytotoxic actions of palytoxin on aortic smooth muscle cells in culture. J. Appl. Toxicol. 2005, 25(5):365-373.
36. Tichadou L., Glaizal M., Armengaud A., Grossel H., Lemée R., Kantin R., Lasalle J.L., Drouet G., Rambaud L., Malfait P., de Haro L. Health impact of unicellular algae of the Ostreopsis genus blooms in the Mediterranean Sea: experience of the French Mediterranean coast surveillance network from 2006 to 2009. Clin. Toxicol. (Phila) 2010, 48(8):839-844.
37. Usami M., Satake M., Ishida S., Inoue A., Kan Y., Yasumoto T. Palytoxin analogues from dinoflagellate Ostreopsis siamensis. J. Am. Chem. Soc. 1995, 117(19):5389-5390.
38. Vale-Gonzalez C., Pazos M.J., Alfonso A., Vieytes M.R., Botana L.M. Study of the neuronal effects of ouabain and palytoxin and their binding to Na,K-ATPases using an optical biosensor. Toxicon 2007, 50(4):541-552.
39. Valverde I., Lago J., Reboreda A., Vieites J.M., Cabado A.G. Characteristics of palytoxin-induced cytotoxicity in neuroblastoma cells. Toxicol. In Vitro 2008, 22(6):1432-1439.
40. Valverde I., Lago J., Vieites J.M., Cabado A.G. In vitro approaches to evaluate palytoxin-induced toxicity and cell death in intestinal cells. J. Appl. Toxicol. 2008, 28(3):294-302.
41. Wu Y.T., Wu S.B., Lee W.Y., Wei Y.H. Mitochondrial respiratory dysfunction-elicited oxidative stress and posttranslational protein modification in mitochondrial diseases. Ann. NY Acad. Sci. 2010, 1201:147-156.