Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing

Neurochemistry International

Volumn 61, Issue 1, 2012, Pages 108-118

  Frykman, Susanne ^a   Teranishi, Yasuhiro ^b   Hur, Ji Yeun ^a   Sandebring, Anna ^a   Goto Yamamoto, Natsuko ^b   Ancarcrona, Maria ^a   Nishimura, Takeshi ^b   Winblad, Bengt ^a   Bogdanovic, Nenad ^a   Schedin Weiss, Sophia ^a   Kihara, Takahiro ^b   Tjernberg, Lars O ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Secretase; Alzheimer disease; Amyloid peptide; NADH dehydrogenase ubiquinone iron sulfur protein 7; Synapse; Tubulin polymerization promoting protein

Indexed keywords

AMYLOID BETA PROTEIN; GAMMA SECRETASE; GLYCOPROTEIN; MEMBRANE PROTEIN; NICASTRIN; NOTCH RECEPTOR; OXIDOREDUCTASE; PRESENILIN 1; PROTEIN APH 1B; PROTEIN NDUFS7; SMALL INTERFERING RNA; TUBULIN POLYMERIZATION PROMOTING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE SILENCING; IMMUNOPRECIPITATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN INTERACTION; RAT; SYNAPSE; SYNAPSE VESICLE; SYNAPTIC MEMBRANE;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, AFFINITY; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, NOTCH; SYNAPSES;

RATTUS;

EID: 84861651898     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.03.016     Document Type: Article

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