-
1
-
-
33845341470
-
Impact of recent increase in incidence on future diabetes burden: US 2005-2050
-
Narayan, K. M., Boyle, J. P., Geiss, L. S., Saaddine, J. B. & Thompson, T. J. Impact of recent increase in incidence on future diabetes burden: US, 2005-2050. Diabetes Care 29, 2114-2116 (2006
-
(2006)
Diabetes Care
, vol.29
, pp. 2114-2116
-
-
Narayan, K.M.1
Boyle, J.P.2
Geiss, L.S.3
Saaddine, J.B.4
Thompson, T.J.5
-
2
-
-
66149131064
-
Diabetes in Asia: Epidemiology, risk factors, and pathophysiology
-
Chan, J. C., Malik, V., Jia, W., Kadowaki, T., Yajnik, C. S., Yoon, K. H. et al. Diabetes in Asia: epidemiology, risk factors, and pathophysiology. JAMA 301, 2129-2140 (2009
-
(2009)
JAMA
, vol.301
, pp. 2129-2140
-
-
Chan, J.C.1
Malik, V.2
Jia, W.3
Kadowaki, T.4
Yajnik, C.S.5
Yoon, K.H.6
-
3
-
-
77950263954
-
Prevalence of diabetes among men and women in China
-
Yang, W., Lu, J., Weng, J., Jia, W., Ji, L., Xiao, J. et al. Prevalence of diabetes among men and women in China. N. Engl. J. Med. 362, 1090-1101 (2010
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 1090-1101
-
-
Yang, W.1
Lu, J.2
Weng, J.3
Jia, W.4
Ji, L.5
Xiao, J.6
-
4
-
-
17044386953
-
Type 2 diabetes: Principles of pathogenesis and therapy
-
Stumvoll, M., Goldstein, B. J. & van Haeften, T. W. Type 2 diabetes: principles of pathogenesis and therapy. Lancet 365, 1333-1346 (2005
-
(2005)
Lancet
, vol.365
, pp. 1333-1346
-
-
Stumvoll, M.1
Goldstein, B.J.2
Van Haeften, T.W.3
-
5
-
-
39649114799
-
Genetic susceptibility to type 2 diabetes and implications for antidiabetic therapy
-
Moore, A. F. & Florez, J. C. Genetic susceptibility to type 2 diabetes and implications for antidiabetic therapy. Annu. Rev. Med. 59, 95-111 (2008
-
(2008)
Annu. Rev. Med.
, vol.59
, pp. 95-111
-
-
Moore, A.F.1
Florez, J.C.2
-
6
-
-
80053927394
-
Genetics of type 2 diabetes: The GWAS era and future perspectives review
-
Imamura, M. & Maeda, S. Genetics of type 2 diabetes: the GWAS era and future perspectives [Review]. Endocr. J. 58, 723-739 (2011
-
(2011)
Endocr. J.
, vol.58
, pp. 723-739
-
-
Imamura, M.1
Maeda, S.2
-
7
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
Zeggini, E., Weedon, M. N., Lindgren, C. M., Frayling, T. M., Elliott, K. S., Lango, H. et al. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 316, 1336-1341 (2007
-
(2007)
Science
, vol.316
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
Lango, H.6
-
8
-
-
34249828965
-
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
-
Steinthorsdottir, V., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Jonsdottir, T., Walters, G. B. et al. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat. Genet. 39, 770-775 (2007
-
(2007)
Nat. Genet.
, vol.39
, pp. 770-775
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Jonsdottir, T.5
Walters, G.B.6
-
9
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott, L. J., Mohlke, K. L., Bonnycastle, L. L., Willer, C. J., Li, Y., Duren, W. L. et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 316, 1341-1345 (2007
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
Duren, W.L.6
-
10
-
-
84969213492
-
Consortium T.W.T.C.C. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Consortium T.W.T.C.C. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678 (2007
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
11
-
-
42349106044
-
Metaanalysis of genome-wide association data and large-Scale replication identifies additional susceptibility loci for type 2 diabetes
-
Zeggini, E., Scott, L. J., Saxena, R., Voight, B. F., Marchini, J. L., Hu, T. et al. Metaanalysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat. Genet. 40, 638-645 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
Marchini, J.L.5
Hu, T.6
-
12
-
-
50449085212
-
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
-
Unoki, H., Takahashi, A., Kawaguchi, T., Hara, K., Horikoshi, M., Andersen, G. et al. SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nat. Genet. 40, 1098-1102 (2008
-
(2008)
Nat. Genet.
, vol.40
, pp. 1098-1102
-
-
Unoki, H.1
Takahashi, A.2
Kawaguchi, T.3
Hara, K.4
Horikoshi, M.5
Andersen, G.6
-
13
-
-
67650248695
-
Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population
-
Takeuchi, F., Serizawa, M., Yamamoto, K., Fujisawa, T., Nakashima, E., Ohnaka, K. et al. Confirmation of multiple risk loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. Diabetes 58, 1690-1699 (2009
-
(2009)
Diabetes
, vol.58
, pp. 1690-1699
-
-
Takeuchi, F.1
Serizawa, M.2
Yamamoto, K.3
Fujisawa, T.4
Nakashima, E.5
Ohnaka, K.6
-
14
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P. et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat. Genet. 42, 579-589 (2010
-
(2010)
Nat. Genet.
, vol.42
, pp. 579-589
-
-
Voight, B.F.1
Scott, L.J.2
Steinthorsdottir, V.3
Morris, A.P.4
Dina, C.5
Welch, R.P.6
-
15
-
-
0037013311
-
Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor
-
Ching, Y. P., Pang, A. S., Lam, W. H., Qi, R. Z. & Wang, J. H. Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor. J. Biol. Chem. 277, 15237-15240 (2002
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15237-15240
-
-
Ching, Y.P.1
Pang, A.S.2
Lam, W.H.3
Qi, R.Z.4
Wang, J.H.5
-
16
-
-
27144441483
-
Cdk5-dependent regulation of glucose-stimulated insulin secretion
-
Wei, F. Y., Nagashima, K., Ohshima, T., Saheki, Y., Lu, Y. F., Matsushita, M. et al. Cdk5-dependent regulation of glucose-stimulated insulin secretion. Nat. Med. 11, 1104-1108 (2005
-
(2005)
Nat. Med.
, vol.11
, pp. 1104-1108
-
-
Wei, F.Y.1
Nagashima, K.2
Ohshima, T.3
Saheki, Y.4
Lu, Y.F.5
Matsushita, M.6
-
17
-
-
33646107369
-
VEGF receptor signallingin control of vascular function
-
Olsson, A. K., Dimberg, A., Kreuger, J. & Claesson-Welsh, L. VEGF receptor signallingin control of vascular function. Nat. Rev. Mol. Cell Biol. 7, 359-371 (2006
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 359-371
-
-
Olsson, A.K.1
Dimberg, A.2
Kreuger, J.3
Claesson-Welsh, L.4
-
18
-
-
25144511910
-
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
-
Takahashi, H. & Shibuya, M. The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions. Clin. Sci. (Lond.) 109, 227-241 (2005
-
(2005)
Clin. Sci. (Lond.)
, vol.109
, pp. 227-241
-
-
Takahashi, H.1
Shibuya, M.2
-
19
-
-
50449104632
-
Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
-
Ng, M. C., Park, K. S., Oh, B., Tam, C. H., Cho, Y. M., Shin, H. D. et al. Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Diabetes 57, 2226-2233 (2008
-
(2008)
Diabetes
, vol.57
, pp. 2226-2233
-
-
Ng, M.C.1
Park, K.S.2
Oh, B.3
Tam, C.H.4
Cho, Y.M.5
Shin, H.D.6
-
20
-
-
77955051399
-
Meta-analysis added power to identify variants in FTO associated with type 2 diabetes and obesity in the Asian population
-
Liu, Y., Liu, Z., Song, Y., Zhou, D., Zhang, D., Zhao, T. et al. Meta-analysis added power to identify variants in FTO associated with type 2 diabetes and obesity in the Asian population. Obesity (Silver Spring) 18, 1619-1624 (2010
-
(2010)
Obesity (Silver Spring)
, vol.18
, pp. 1619-1624
-
-
Liu, Y.1
Liu, Z.2
Song, Y.3
Zhou, D.4
Zhang, D.5
Zhao, T.6
-
21
-
-
81755176633
-
Prevalence on overweight and obesity in han uygur and hazakh in adults from xinjiang
-
Liu, C., Ma, X., Ma, Y. T., Liu, F., Yang, Y. N., Huang, D. et al. Prevalence on overweight and obesity in Han, Uygur and Hazakh in adults from Xinjiang. Zhonghua Liu Xing Bing Xue Za Zhi 31, 1139-1143 (2010
-
(2010)
Zhonghua Liu Xing Bing Xue Za Zhi
, vol.31
, pp. 1139-1143
-
-
Liu, C.1
Ma, X.2
Ma, Y.T.3
Liu, F.4
Yang, Y.N.5
Huang, D.6
-
22
-
-
79960929526
-
A genome-Wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese
-
Hu, Z., Wu, C., Shi, Y., Guo, H., Zhao, X., Yin, Z. et al. A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat. Genet. 43, 792-796 (2011
-
(2011)
Nat. Genet.
, vol.43
, pp. 792-796
-
-
Hu, Z.1
Wu, C.2
Shi, Y.3
Guo, H.4
Zhao, X.5
Yin, Z.6
-
23
-
-
70449433016
-
PParg, kcnj11, cdkal1, cdkn2a-cdkn2b, ide-kif11-hhex, igf2bp2 and slc30a8 are associated with type 2 diabetes in a chinese population
-
Hu, C., Zhang, R., Wang, C., Wang, J., Ma, X., Lu, J. et al. PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population. PLoS. One. 4, e7643 (2009
-
(2009)
PLoS. One.
, vol.4
-
-
Hu, C.1
Zhang, R.2
Wang, C.3
Wang, J.4
Ma, X.5
Lu, J.6
-
24
-
-
56349170898
-
Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
-
Wu, Y., Li, H., Loos, R. J., Yu, Z., Ye, X., Chen, L. et al. Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population. Diabetes 57, 2834-2842 (2008
-
(2008)
Diabetes
, vol.57
, pp. 2834-2842
-
-
Wu, Y.1
Li, H.2
Loos, R.J.3
Yu, Z.4
Ye, X.5
Chen, L.6
-
25
-
-
53549096229
-
Positive association between variations in cdkal1 and type 2 diabetes in han chinese individuals
-
Liu, Y., Yu, L., Zhang, D., Chen, Z., Zhou, D. Z., Zhao, T. et al. Positive association between variations in CDKAL1 and type 2 diabetes in Han Chinese individuals. Diabetologia 51, 2134-2137 (2008
-
(2008)
Diabetologia
, vol.51
, pp. 2134-2137
-
-
Liu, Y.1
Yu, L.2
Zhang, D.3
Chen, Z.4
Zhou, D.Z.5
Zhao, T.6
-
26
-
-
77953438355
-
Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population
-
Lin, Y., Li, P., Cai, L., Zhang, B., Tang, X., Zhang, X. et al. Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population. BMC Med. Genet. 11, 97 (2010
-
(2010)
BMC Med. Genet.
, vol.11
, pp. 97
-
-
Lin, Y.1
Li, P.2
Cai, L.3
Zhang, B.4
Tang, X.5
Zhang, X.6
-
27
-
-
77949346987
-
Investigation of type 2 diabetes risk alleles support CDKN2A/B CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort
-
Wen, J., Ronn, T., Olsson, A., Yang, Z., Lu, B., Du, Y. et al. Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort. PLoS. One. 5, e9153 (2010
-
(2010)
PLoS. One.
, vol.5
-
-
Wen, J.1
Ronn, T.2
Olsson, A.3
Yang, Z.4
Lu, B.5
Du, Y.6
-
28
-
-
77952701364
-
Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population
-
Han, X., Luo, Y., Ren, Q., Zhang, X., Wang, F., Sun, X. et al. Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population. BMC Med. Genet. 11, 81 (2010
-
(2010)
BMC Med. Genet.
, vol.11
, pp. 81
-
-
Han, X.1
Luo, Y.2
Ren, Q.3
Zhang, X.4
Wang, F.5
Sun, X.6
-
29
-
-
33749389928
-
Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity
-
Ubeda, M., Rukstalis, J. M. & Habener, J. F. Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity. J. Biol. Chem. 281, 28858-28864 (2006
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 28858-28864
-
-
Ubeda, M.1
Rukstalis, J.M.2
Habener, J.F.3
-
30
-
-
80052375980
-
Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice
-
Wei, F. Y., Suzuki, T., Watanabe, S., Kimura, S., Kaitsuka, T., Fujimura, A. et al. Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice. J. Clin. Invest. 121, 3598-3608 (2011
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3598-3608
-
-
Wei, F.Y.1
Suzuki, T.2
Watanabe, S.3
Kimura, S.4
Kaitsuka, T.5
Fujimura, A.6
-
31
-
-
80055085362
-
Functional loss of cdkal1, a novel trna modification enzyme, causes the development of type 2 diabetes [review]
-
Wei, F. Y. & Tomizawa, K. Functional loss of Cdkal1, a novel tRNA modification enzyme, causes the development of type 2 diabetes [Review]. Endocr. J. 58, 819-825 (2011
-
(2011)
Endocr. J.
, vol.58
, pp. 819-825
-
-
Wei, F.Y.1
Tomizawa, K.2
-
32
-
-
51549112931
-
Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes
-
Staiger, H., Machicao, F., Kantartzis, K., Schafer, S. A., Kirchhoff, K., Guthoff, M. et al. Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes. PLoS. One. 3, e3019 (2008
-
(2008)
PLoS. One.
, vol.3
-
-
Staiger, H.1
Machicao, F.2
Kantartzis, K.3
Schafer, S.A.4
Kirchhoff, K.5
Guthoff, M.6
-
33
-
-
79951705812
-
Type 2 diabetes (T2D) associated polymorphisms regulate expression of adjacent transcripts in transformed lymphocytes, adipose, and muscle from Caucasian and African-American subjects
-
Sharma, N. K., Langberg, K. A., Mondal, A. K., Elbein, S. C. & Das, S. K. Type 2 diabetes (T2D) associated polymorphisms regulate expression of adjacent transcripts in transformed lymphocytes, adipose, and muscle from Caucasian and African-American subjects. J. Clin. Endocrinol. Metab. 96, E394-403 (2011
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
-
-
Sharma, N.K.1
Langberg, K.A.2
Mondal, A.K.3
Elbein, S.C.4
Das, S.K.5
-
34
-
-
84863393723
-
Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study
-
Langberg, K. A., Ma, L., Sharma, N. K., Hanis, C. L., Elbein, S. C., Hasstedt, S. J. et al. Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study. J. Hum. Genet. 57, 57-61 (2011
-
(2011)
J. Hum. Genet.
, vol.57
, pp. 57-61
-
-
Langberg, K.A.1
Ma, L.2
Sharma, N.K.3
Hanis, C.L.4
Elbein, S.C.5
Hasstedt, S.J.6
-
35
-
-
67650655994
-
Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals
-
Omori, S., Tanaka, Y., Horikoshi, M., Takahashi, A., Hara, K., Hirose, H. et al. Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals. Diabetologia 52, 1554-1560 (2009
-
(2009)
Diabetologia
, vol.52
, pp. 1554-1560
-
-
Omori, S.1
Tanaka, Y.2
Horikoshi, M.3
Takahashi, A.4
Hara, K.5
Hirose, H.6
-
36
-
-
84655162045
-
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
-
Cho, Y. S., Chen, C. H., Hu, C., Long, J., Hee Ong, R. T., Sim, X. et al. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat. Genet. 44, 67-72 (2011)
-
(2011)
Nat. Genet.
, vol.44
, pp. 67-72
-
-
Cho, Y.S.1
Chen, C.H.2
Hu, C.3
Long, J.4
Hee Ong, R.T.5
Sim, X.6
|