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Volumn 5, Issue 5, 2012, Pages 493-513

Selecting molecular recognition. what can existing aptamers tell us about their inherent recognition capabilities and modes of interaction?

Author keywords

Aptamers; Molecular recognition; Nucleic acids

Indexed keywords

APTAMER; CARBOHYDRATE; GREEN FLUORESCENT PROTEIN; NUCLEASE; PEPTIDE APTAMER;

EID: 84861630170     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph5050493     Document Type: Review
Times cited : (13)

References (99)
  • 1
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk, C.; Gold, L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 1990, 249, 505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 2
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington, A.D.; Szostak, J.W. In vitro selection of RNA molecules that bind specific ligands. Nature 1990, 346, 818-822.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 3
  • 5
    • 84861621175 scopus 로고    scopus 로고
    • Therapeutic Oligonucleotides
    • Biomolecular Sciences: London, UK
    • Kurreck, J.E. Therapeutic Oligonucleotides; Royal Society of Chemistry, Biomolecular Sciences: London, UK, 2008; p. 345.
    • (2008) Royal Society of Chemistry , pp. 345
    • Kurreck, J.E.1
  • 6
    • 0030804766 scopus 로고    scopus 로고
    • A new peptide vector for efficient delivery of oligonucleotides into mammalian cells
    • Morris, M.C.; Vidal, P.; Chaloin, L.; Heitz, F.; Divita, G. A new peptide vector for efficient delivery of oligonucleotides into mammalian cells. Nucleic Acids Res. 1997, 25, 2730-2736.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2730-2736
    • Morris, M.C.1    Vidal, P.2    Chaloin, L.3    Heitz, F.4    Divita, G.5
  • 8
    • 77954914696 scopus 로고    scopus 로고
    • Aptamers for targeted drug delivery
    • Ray, P.; White, R.R. Aptamers for targeted drug delivery. Pharmaceuticals 2010, 3, 1761-1778.
    • (2010) Pharmaceuticals , vol.3 , pp. 1761-1778
    • Ray, P.1    White, R.R.2
  • 12
    • 34548484580 scopus 로고    scopus 로고
    • Delivery of short interfering RNA using endosomolytic cell-penetrating peptides
    • Lundberg, P.; El-Andaloussi, S.; Sutlu, T.; Johansson, H.; Langel, U. Delivery of short interfering RNA using endosomolytic cell-penetrating peptides. FASEB J. 2007, 21, 2664-2671.
    • (2007) FASEB J , vol.21 , pp. 2664-2671
    • Lundberg, P.1    El-Andaloussi, S.2    Sutlu, T.3    Johansson, H.4    Langel, U.5
  • 13
    • 84856540532 scopus 로고    scopus 로고
    • Cell-penetrating RNAs: New keys to the castle
    • Burke, D.H. Cell-penetrating RNAs: New keys to the castle. Mol. Ther. 2012, 20, 251-253.
    • (2012) Mol. Ther , vol.20 , pp. 251-253
    • Burke, D.H.1
  • 14
    • 0031686486 scopus 로고    scopus 로고
    • Recombination, RNA evolution, and bifunctional RNA molecules isolated through chimeric SELEX
    • Burke, D.H.; Willis, J.H. Recombination, RNA evolution, and bifunctional RNA molecules isolated through chimeric SELEX. RNA 1998, 4, 1165-1175.
    • (1998) RNA , vol.4 , pp. 1165-1175
    • Burke, D.H.1    Willis, J.H.2
  • 15
    • 84856389509 scopus 로고    scopus 로고
    • RNA-based therapeutics: Current progress and future prospects
    • Burnett, J.C.; Rossi, J.J. RNA-based therapeutics: Current progress and future prospects. Chem. Biol. 2012, 19, 60-71.
    • (2012) Chem. Biol , vol.19 , pp. 60-71
    • Burnett, J.C.1    Rossi, J.J.2
  • 17
    • 48349105059 scopus 로고    scopus 로고
    • Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy
    • Zhou, J.; Li, H.; Li, S.; Zaia, J.; Rossi, J.J. Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy. Mol. Ther. 2008, 16, 1481-1489.
    • (2008) Mol. Ther , vol.16 , pp. 1481-1489
    • Zhou, J.1    Li, H.2    Li, S.3    Zaia, J.4    Rossi, J.J.5
  • 19
    • 79551481153 scopus 로고    scopus 로고
    • Development of highly nuclease-resistant chemically-modified oligonucleotides
    • Matsuda, A. Development of highly nuclease-resistant chemically-modified oligonucleotides. Yakugaku Zasshi 2011, 131, 285-298.
    • (2011) Yakugaku Zasshi , vol.131 , pp. 285-298
    • Matsuda, A.1
  • 21
    • 26944469056 scopus 로고    scopus 로고
    • Interferon-beta induction through toll-like receptor 3 depends on double-stranded RNA structure
    • Okahira, S.; Nishikawa, F.; Nishikawa, S.; Akazawa, T.; Seya, T.; Matsumoto, M. Interferon-beta induction through toll-like receptor 3 depends on double-stranded RNA structure. DNA Cell Biol. 2005, 24, 614-623.
    • (2005) DNA Cell Biol , vol.24 , pp. 614-623
    • Okahira, S.1    Nishikawa, F.2    Nishikawa, S.3    Akazawa, T.4    Seya, T.5    Matsumoto, M.6
  • 23
    • 84857222840 scopus 로고    scopus 로고
    • 2nd. Degradation of nuclease-stabilized RNA oligonucleotides in Mycoplasma-contaminated cell culture media
    • Hernandez, F.J.; Stockdale, K.R.; Huang, L.; Horswill, A.R.; Behlke, M.A.; McNamara, J.O., 2nd. Degradation of nuclease-stabilized RNA oligonucleotides in Mycoplasma-contaminated cell culture media. Nucleic Acid Ther. 2012, 22, 58-68.
    • (2012) Nucleic Acid Ther , vol.22 , pp. 58-68
    • Hernandez, F.J.1    Stockdale, K.R.2    Huang, L.3    Horswill, A.R.4    Behlke, M.A.5    McNamara, J.O.6
  • 24
    • 0014024876 scopus 로고
    • N-4-methyl-2'-O-methyl cytidine and other methyl-substituted nucleoside constituents of Escherichia coli ribosomal and soluble RNA
    • Nichols, J.L.; Lane, B.G. N-4-methyl-2'-O-methyl cytidine and other methyl-substituted nucleoside constituents of Escherichia coli ribosomal and soluble RNA. Biochim. Biophys. Acta 1966, 119, 649-651.
    • (1966) Biochim. Biophys. Acta , vol.119 , pp. 649-651
    • Nichols, J.L.1    Lane, B.G.2
  • 25
    • 0015373444 scopus 로고
    • 2'-O-methylation of adenosine, guanosine, uridine, and cytidine in RNA of isolated rat liver nuclei
    • Al-Arif, A.; Sporn, M.B. 2'-O-methylation of adenosine, guanosine, uridine, and cytidine in RNA of isolated rat liver nuclei. Proc. Natl. Acad. Sci. USA 1972, 69, 1716-1719.
    • (1972) Proc. Natl. Acad. Sci. USA , vol.69 , pp. 1716-1719
    • Al-Arif, A.1    Sporn, M.B.2
  • 26
    • 4444326623 scopus 로고    scopus 로고
    • Evolution of a T7 RNA polymerase variant that transcribes 2'-O-methyl RNA
    • Chelliserrykattil, J.; Ellington, A.D. Evolution of a T7 RNA polymerase variant that transcribes 2'-O-methyl RNA. Nat. Biotechnol. 2004, 22, 1155-1160.
    • (2004) Nat. Biotechnol , vol.22 , pp. 1155-1160
    • Chelliserrykattil, J.1    Ellington, A.D.2
  • 28
  • 29
    • 0142043453 scopus 로고    scopus 로고
    • Spiegelmers: Biostable aptamers
    • Eulberg, D.; Klussmann, S. Spiegelmers: Biostable aptamers. ChemBioChem 2003, 4, 979-983.
    • (2003) ChemBioChem , vol.4 , pp. 979-983
    • Eulberg, D.1    Klussmann, S.2
  • 35
    • 84860579546 scopus 로고    scopus 로고
    • Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker
    • Ray, P.; Rialon-Guevara, K.L.; Veras, E.; Sullenger, B.A.; White, R.R. Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker. J. Clin. Invest. 2012, 122, 1734-1741.
    • (2012) J. Clin. Invest , vol.122 , pp. 1734-1741
    • Ray, P.1    Rialon-Guevara, K.L.2    Veras, E.3    Sullenger, B.A.4    White, R.R.5
  • 36
    • 56249134876 scopus 로고    scopus 로고
    • Higher-order association states of cellular ERBB3 probed with photo-cross-linkable aptamers
    • Park, E.; Baron, R.; Landgraf, R. Higher-order association states of cellular ERBB3 probed with photo-cross-linkable aptamers. Biochemistry 2008, 47, 11992-12005.
    • (2008) Biochemistry , vol.47 , pp. 11992-12005
    • Park, E.1    Baron, R.2    Landgraf, R.3
  • 37
    • 0029557118 scopus 로고
    • Using in vitro selection to direct the covalent attachment of human immunodeficiency virus type 1 Rev protein to high-affinity RNA ligands
    • Jensen, K.B.; Atkinson, B.L.; Willis, M.C.; Koch, T.H.; Gold, L. Using in vitro selection to direct the covalent attachment of human immunodeficiency virus type 1 Rev protein to high-affinity RNA ligands. Proc. Natl. Acad. Sci. USA 1995, 92, 12220-12224.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 12220-12224
    • Jensen, K.B.1    Atkinson, B.L.2    Willis, M.C.3    Koch, T.H.4    Gold, L.5
  • 38
    • 0029077840 scopus 로고
    • Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity
    • Cummins, L.L.; Owens, S.R.; Risen, L.M.; Lesnik, E.A.; Freier, S.M.; McGee, D.; Guinosso, C.J.; Cook, P.D. Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity. Nucleic Acids Res. 1995, 23, 2019-2024.
    • (1995) Nucleic Acids Res , vol.23 , pp. 2019-2024
    • Cummins, L.L.1    Owens, S.R.2    Risen, L.M.3    Lesnik, E.A.4    Freier, S.M.5    McGee, D.6    Guinosso, C.J.7    Cook, P.D.8
  • 40
    • 58149085388 scopus 로고    scopus 로고
    • Leakage and slow allostery limit performance of single drug-sensing aptazyme molecules based on the hammerhead ribozyme
    • de Silva, C.; Walter, N.G. Leakage and slow allostery limit performance of single drug-sensing aptazyme molecules based on the hammerhead ribozyme. RNA 2009, 15, 76-84.
    • (2009) RNA , vol.15 , pp. 76-84
    • de Silva, C.1    Walter, N.G.2
  • 41
    • 78649538725 scopus 로고    scopus 로고
    • Molecular interaction studies of vascular endothelial growth factor with RNA aptamers
    • Zhang, X.; Yadavalli, V.K. Molecular interaction studies of vascular endothelial growth factor with RNA aptamers. Analyst 2010, 135, 2014-2021.
    • (2010) Analyst , vol.135 , pp. 2014-2021
    • Zhang, X.1    Yadavalli, V.K.2
  • 43
    • 0027172294 scopus 로고
    • The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer
    • Padmanabhan, K.; Padmanabhan, K.P.; Ferrara, J.D.; Sadler, J.E.; Tulinsky, A. The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer. J. Biol. Chem. 1993, 268, 17651-17654.
    • (1993) J. Biol. Chem , vol.268 , pp. 17651-17654
    • Padmanabhan, K.1    Padmanabhan, K.P.2    Ferrara, J.D.3    Sadler, J.E.4    Tulinsky, A.5
  • 44
    • 0027537022 scopus 로고
    • A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA
    • Wang, K.Y.; McCurdy, S.; Shea, R.G.; Swaminathan, S.; Bolton, P.H. A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA. Biochemistry 1993, 32, 1899-1904.
    • (1993) Biochemistry , vol.32 , pp. 1899-1904
    • Wang, K.Y.1    McCurdy, S.2    Shea, R.G.3    Swaminathan, S.4    Bolton, P.H.5
  • 45
    • 0034628673 scopus 로고    scopus 로고
    • The 1.3 A crystal structure of a biotin-binding pseudoknot and the basis for RNA molecular recognition
    • Nix, J.; Sussman, D.; Wilson, C. The 1.3 A crystal structure of a biotin-binding pseudoknot and the basis for RNA molecular recognition. J. Mol. Biol. 2000, 296, 1235-1244.
    • (2000) J. Mol. Biol , vol.296 , pp. 1235-1244
    • Nix, J.1    Sussman, D.2    Wilson, C.3
  • 47
    • 0032500736 scopus 로고    scopus 로고
    • Controlling gene expression in living cells through small molecule-RNA interactions
    • Werstuck, G.; Green, M.R. Controlling gene expression in living cells through small molecule-RNA interactions. Science 1998, 282, 296-298.
    • (1998) Science , vol.282 , pp. 296-298
    • Werstuck, G.1    Green, M.R.2
  • 48
    • 0031171217 scopus 로고    scopus 로고
    • Rational design of allosteric ribozymes
    • Tang, J.; Breaker, R.R. Rational design of allosteric ribozymes. Chem. Biol. 1997, 4, 453-459.
    • (1997) Chem. Biol , vol.4 , pp. 453-459
    • Tang, J.1    Breaker, R.R.2
  • 50
    • 27144526390 scopus 로고    scopus 로고
    • An artificial riboswitch for controlling pre-mRNA splicing
    • Kim, D.S.; Gusti, V.; Pillai, S.G.; Gaur, R.K. An artificial riboswitch for controlling pre-mRNA splicing. RNA 2005, 11, 1667-1677.
    • (2005) RNA , vol.11 , pp. 1667-1677
    • Kim, D.S.1    Gusti, V.2    Pillai, S.G.3    Gaur, R.K.4
  • 51
    • 34547639506 scopus 로고    scopus 로고
    • Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast
    • Weigand, J.E.; Suess, B. Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast. Nucleic Acids Res. 2007, 35, 4179-4185.
    • (2007) Nucleic Acids Res , vol.35 , pp. 4179-4185
    • Weigand, J.E.1    Suess, B.2
  • 53
    • 0028224199 scopus 로고
    • High-resolution molecular discrimination by RNA
    • Jenison, R.D.; Gill, S.C.; Pardi, A.; Polisky, B. High-resolution molecular discrimination by RNA. Science 1994, 263, 1425-1429.
    • (1994) Science , vol.263 , pp. 1425-1429
    • Jenison, R.D.1    Gill, S.C.2    Pardi, A.3    Polisky, B.4
  • 55
    • 0024580111 scopus 로고
    • Site-specific interaction of intercalating drugs with a branched DNA molecule
    • Guo, Q.; Seeman, N.C.; Kallenbach, N.R. Site-specific interaction of intercalating drugs with a branched DNA molecule. Biochemistry 1989, 28, 2355-2359.
    • (1989) Biochemistry , vol.28 , pp. 2355-2359
    • Guo, Q.1    Seeman, N.C.2    Kallenbach, N.R.3
  • 56
    • 78649817584 scopus 로고    scopus 로고
    • Detecting hydrophobic molecules with nucleic acid-based receptors
    • Stojanovic, M.N.; Worgall, T.S. Detecting hydrophobic molecules with nucleic acid-based receptors. Curr. Opin. Chem. Biol. 2010, 14, 751-757.
    • (2010) Curr. Opin. Chem. Biol , vol.14 , pp. 751-757
    • Stojanovic, M.N.1    Worgall, T.S.2
  • 58
    • 0034193211 scopus 로고    scopus 로고
    • Interaction of three-way DNA junctions with steroids
    • Kato, T.; Yano, K.; Ikebukuro, K.; Karube, I. Interaction of three-way DNA junctions with steroids. Nucleic Acids Res. 2000, 28, 1963-1968.
    • (2000) Nucleic Acids Res , vol.28 , pp. 1963-1968
    • Kato, T.1    Yano, K.2    Ikebukuro, K.3    Karube, I.4
  • 60
    • 0032514717 scopus 로고    scopus 로고
    • Functional requirements for specific ligand recognition by a biotin-binding RNA pseudoknot
    • Wilson, C.; Nix, J.; Szostak, J. Functional requirements for specific ligand recognition by a biotin-binding RNA pseudoknot. Biochemistry 1998, 37, 14410-14419.
    • (1998) Biochemistry , vol.37 , pp. 14410-14419
    • Wilson, C.1    Nix, J.2    Szostak, J.3
  • 61
    • 77955594327 scopus 로고    scopus 로고
    • Aptamer-based carbohydrate recognition
    • Sun, W.; Du, L.; Li, M. Aptamer-based carbohydrate recognition. Curr. Pharm. Des. 2010, 16, 2269-2278.
    • (2010) Curr. Pharm. Des , vol.16 , pp. 2269-2278
    • Sun, W.1    Du, L.2    Li, M.3
  • 62
    • 0033565449 scopus 로고    scopus 로고
    • Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer
    • Jiang, L.; Majumdar, A.; Hu, W.; Jaishree, T.J.; Xu, W.; Patel, D.J. Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer. Structure 1999, 7, 817-827.
    • (1999) Structure , vol.7 , pp. 817-827
    • Jiang, L.1    Majumdar, A.2    Hu, W.3    Jaishree, T.J.4    Xu, W.5    Patel, D.J.6
  • 63
    • 0031781844 scopus 로고    scopus 로고
    • In vitro selection of apta-mers that recognize a monosaccharide
    • Kawakami, J.; Kawase, Y.; Sugimoto, N. In vitro selection of apta-mers that recognize a monosaccharide. Anal. Chim. Acta 1998, 365, 95-100.
    • (1998) Anal. Chim. Acta , vol.365 , pp. 95-100
    • Kawakami, J.1    Kawase, Y.2    Sugimoto, N.3
  • 65
    • 0017521755 scopus 로고
    • Purification and properties of the periplasmic glucose-binding protein of Pseudomonas aeruginosa
    • Stinson, M.W.; Cohen, M.A.; Merrick, J.M. Purification and properties of the periplasmic glucose-binding protein of Pseudomonas aeruginosa. J. Bacteriol. 1977, 131, 672-681.
    • (1977) J. Bacteriol , vol.131 , pp. 672-681
    • Stinson, M.W.1    Cohen, M.A.2    Merrick, J.M.3
  • 66
    • 1342279558 scopus 로고    scopus 로고
    • Sialyllactose-binding modified DNA aptamer bearing additional functionality by SELEX
    • Masud, M.M.; Kuwahara, M.; Ozaki, H.; Sawai, H. Sialyllactose-binding modified DNA aptamer bearing additional functionality by SELEX. Bioorg. Med. Chem. 2004, 12, 1111-1120.
    • (2004) Bioorg. Med. Chem , vol.12 , pp. 1111-1120
    • Masud, M.M.1    Kuwahara, M.2    Ozaki, H.3    Sawai, H.4
  • 69
    • 0026575221 scopus 로고
    • Selection of single-stranded DNA molecules that bind and inhibit human thrombin
    • Bock, L.C.; Griffin, L.C.; Latham, J.A.; Vermaas, E.H.; Toole, J.J. Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature 1992, 355, 564-566.
    • (1992) Nature , vol.355 , pp. 564-566
    • Bock, L.C.1    Griffin, L.C.2    Latham, J.A.3    Vermaas, E.H.4    Toole, J.J.5
  • 70
    • 0028347781 scopus 로고
    • Isolation and identification of aptamers from defibrotide that act as thrombin antagonists in vitro
    • Bracht, F.; Schror, K. Isolation and identification of aptamers from defibrotide that act as thrombin antagonists in vitro. Biochem. Biophys. Res. Commun. 1994, 200, 933-937.
    • (1994) Biochem. Biophys. Res. Commun , vol.200 , pp. 933-937
    • Bracht, F.1    Schror, K.2
  • 71
    • 80052921815 scopus 로고    scopus 로고
    • Studies of the binding mechanism between aptamers and thrombin by circular dichroism, surface plasmon resonance and isothermal titration calorimetry
    • Lin, P.H.; Chen, R.H.; Lee, C.H.; Chang, Y.; Chen, C.S.; Chen, W.Y. Studies of the binding mechanism between aptamers and thrombin by circular dichroism, surface plasmon resonance and isothermal titration calorimetry. Colloids Surf. B Biointerfaces 2011, 88, 552-558.
    • (2011) Colloids Surf B Biointerfaces , vol.88 , pp. 552-558
    • Lin, P.H.1    Chen, R.H.2    Lee, C.H.3    Chang, Y.4    Chen, C.S.5    Chen, W.Y.6
  • 72
    • 33845388596 scopus 로고    scopus 로고
    • First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity
    • Dyke, C.K.; Steinhubl, S.R.; Kleiman, N.S.; Cannon, R.O.; Aberle, L.G.; Lin, M.; Myles, S.K.; Melloni, C.; Harrington, R.A.; Alexander, J.H.; et al. First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: A phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity. Circulation 2006, 114, 2490-2497.
    • (2006) Circulation , vol.114 , pp. 2490-2497
    • Dyke, C.K.1    Steinhubl, S.R.2    Kleiman, N.S.3    Cannon, R.O.4    Aberle, L.G.5    Lin, M.6    Myles, S.K.7    Melloni, C.8    Harrington, R.A.9    Alexander, J.H.10
  • 73
    • 80052480929 scopus 로고    scopus 로고
    • Dose selection for a direct and selective factor IXa inhibitor and its complementary reversal agent: Translating pharmacokinetic and pharmacodynamic properties of the REG1 system to clinical trial design
    • Povsic, T.J.; Cohen, M.G.; Chan, M.Y.; Zelenkofske, S.L.; Wargin, W.A.; Harrington, R.A.; Alexander, J.H.; Rusconi, C.P.; Becker, R.C. Dose selection for a direct and selective factor IXa inhibitor and its complementary reversal agent: Translating pharmacokinetic and pharmacodynamic properties of the REG1 system to clinical trial design. J. Thromb. Thrombolysis 2011, 32, 21-31.
    • (2011) J. Thromb. Thrombolysis , vol.32 , pp. 21-31
    • Povsic, T.J.1    Cohen, M.G.2    Chan, M.Y.3    Zelenkofske, S.L.4    Wargin, W.A.5    Harrington, R.A.6    Alexander, J.H.7    Rusconi, C.P.8    Becker, R.C.9
  • 74
    • 0034603154 scopus 로고    scopus 로고
    • Adaptive recognition by nucleic acid aptamers
    • Hermann, T.; Patel, D.J. Adaptive recognition by nucleic acid aptamers. Science 2000, 287, 820-825.
    • (2000) Science , vol.287 , pp. 820-825
    • Hermann, T.1    Patel, D.J.2
  • 76
    • 1342345186 scopus 로고    scopus 로고
    • Molecular mimicry of the NF-kappaB DNA target site by a selected RNA aptamer
    • Ghosh, G.; Huang, D.B.; Huxford, T. Molecular mimicry of the NF-kappaB DNA target site by a selected RNA aptamer. Curr. Opin. Struct. Biol. 2004, 14, 21-27.
    • (2004) Curr. Opin. Struct. Biol , vol.14 , pp. 21-27
    • Ghosh, G.1    Huang, D.B.2    Huxford, T.3
  • 77
    • 81555208934 scopus 로고    scopus 로고
    • Aptamers can discriminate alkaline proteins with high specificity
    • Yu, H.; Jiang, B.; Chaput, J.C. Aptamers can discriminate alkaline proteins with high specificity. ChemBioChem 2011, 12, 2659-2666.
    • (2011) ChemBioChem , vol.12 , pp. 2659-2666
    • Yu, H.1    Jiang, B.2    Chaput, J.C.3
  • 78
    • 0041923790 scopus 로고    scopus 로고
    • Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3
    • Chen, C.H.; Chernis, G.A.; Hoang, V.Q.; Landgraf, R. Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3. Proc. Natl. Acad. Sci. USA 2003, 100, 9226-9231.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 9226-9231
    • Chen, C.H.1    Chernis, G.A.2    Hoang, V.Q.3    Landgraf, R.4
  • 79
    • 80052169101 scopus 로고    scopus 로고
    • In vitro selection of RNA aptamer and specific targeting of ErbB2 in breast cancer cells
    • Kim, M.Y.; Jeong, S. In vitro selection of RNA aptamer and specific targeting of ErbB2 in breast cancer cells. Nucleic Acid Ther. 2011, 21, 173-178.
    • (2011) Nucleic Acid Ther , vol.21 , pp. 173-178
    • Kim, M.Y.1    Jeong, S.2
  • 81
    • 42949089427 scopus 로고    scopus 로고
    • Arginine-modified DNA aptamers that show enantioselective recognition of the dicarboxylic acid moiety of glutamic acid
    • Ohsawa, K.; Kasamatsu, T.; Nagashima, J.; Hanawa, K.; Kuwahara, M.; Ozaki, H.; Sawai, H. Arginine-modified DNA aptamers that show enantioselective recognition of the dicarboxylic acid moiety of glutamic acid. Anal. Sci. 2008, 24, 167-172.
    • (2008) Anal. Sci , vol.24 , pp. 167-172
    • Ohsawa, K.1    Kasamatsu, T.2    Nagashima, J.3    Hanawa, K.4    Kuwahara, M.5    Ozaki, H.6    Sawai, H.7
  • 82
    • 0037434791 scopus 로고    scopus 로고
    • Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
    • Cho, H.S.; Mason, K.; Ramyar, K.X.; Stanley, A.M.; Gabelli, S.B.; Denney, D.W.; Leahy, D.J. Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab. Nature 2003, 412, 756-760.
    • (2003) Nature , vol.412 , pp. 756-760
    • Cho, H.S.1    Mason, K.2    Ramyar, K.X.3    Stanley, A.M.4    Gabelli, S.B.5    Denney, D.W.6    Leahy, D.J.7
  • 83
    • 39049174189 scopus 로고    scopus 로고
    • Site-specific incorporation of fluorescent probes into RNA by specific transcription using unnatural base pairs
    • Kimoto, M.; Kawai, R.; Mitsui, T.; Harada, Y.; Sato, A.; Yokoyama, S.; Hirao, I. Site-specific incorporation of fluorescent probes into RNA by specific transcription using unnatural base pairs. Nucleic Acids Symp. Ser. (Oxf.) 2005, 49, 287-288.
    • (2005) Nucleic Acids Symp. Ser. (Oxf.) , vol.49 , pp. 287-288
    • Kimoto, M.1    Kawai, R.2    Mitsui, T.3    Harada, Y.4    Sato, A.5    Yokoyama, S.6    Hirao, I.7
  • 84
    • 35348969892 scopus 로고    scopus 로고
    • Light-up Hoechst-DNA aptamer pair: Generation of an aptamer-selective fluorophore from a conventional DNA-staining dye
    • Sando, S.; Narita, A.; Aoyama, Y. Light-up Hoechst-DNA aptamer pair: Generation of an aptamer-selective fluorophore from a conventional DNA-staining dye. ChemBioChem 2007, 8, 1795-1803.
    • (2007) ChemBioChem , vol.8 , pp. 1795-1803
    • Sando, S.1    Narita, A.2    Aoyama, Y.3
  • 85
    • 0344430112 scopus 로고    scopus 로고
    • Aptamers switch on fluorescence of triphenylmethane dyes
    • Babendure, J.R.; Adams, S.R.; Tsien, R.Y. Aptamers switch on fluorescence of triphenylmethane dyes. J. Am. Chem. Soc. 2003, 125, 14716-14717.
    • (2003) J. Am. Chem. Soc , vol.125 , pp. 14716-14717
    • Babendure, J.R.1    Adams, S.R.2    Tsien, R.Y.3
  • 86
    • 75649115391 scopus 로고    scopus 로고
    • Label-free fluorescent aptamer sensor based on regulation of malachite green fluorescence
    • Xu, W.; Lu, Y. Label-free fluorescent aptamer sensor based on regulation of malachite green fluorescence. Anal. Chem. 2010, 82, 574-578.
    • (2010) Anal. Chem , vol.82 , pp. 574-578
    • Xu, W.1    Lu, Y.2
  • 87
    • 79960959180 scopus 로고    scopus 로고
    • RNA mimics of green fluorescent protein
    • Paige, J.S.; Wu, K.Y.; Jaffrey, S.R. RNA mimics of green fluorescent protein. Science 2011, 333, 642-646.
    • (2011) Science , vol.333 , pp. 642-646
    • Paige, J.S.1    Wu, K.Y.2    Jaffrey, S.R.3
  • 89
    • 67651154401 scopus 로고    scopus 로고
    • In silico selection of RNA aptamers
    • Chushak, Y.; Stone, M.O. In silico selection of RNA aptamers. Nucleic Acids Res. 2009, 37, e87.
    • (2009) Nucleic Acids Res , vol.87 , pp. 37
    • Chushak, Y.1    Stone, M.O.2
  • 90
    • 77954576691 scopus 로고    scopus 로고
    • A modeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization
    • Joubert, M.K.; Kinsley, N.; Capovilla, A.; Sewell, B.T.; Jaffer, M.A.; Khati, M. A modeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization. Biochemistry 2010, 49, 5880-5890.
    • (2010) Biochemistry , vol.49 , pp. 5880-5890
    • Joubert, M.K.1    Kinsley, N.2    Capovilla, A.3    Sewell, B.T.4    Jaffer, M.A.5    Khati, M.6
  • 91
    • 79958073354 scopus 로고    scopus 로고
    • Computational approaches to RNA structure prediction, analysis, and design
    • Laing, C.; Schlick, T. Computational approaches to RNA structure prediction, analysis, and design. Curr. Opin. Struct. Biol. 2011, 21, 306-318.
    • (2011) Curr. Opin. Struct. Biol , vol.21 , pp. 306-318
    • Laing, C.1    Schlick, T.2
  • 92
    • 41849128549 scopus 로고    scopus 로고
    • Minimal primer and primer-free SELEX protocols for selection of aptamers from random DNA libraries
    • Pan, W.; Xin, P.; Clawson, G.A. Minimal primer and primer-free SELEX protocols for selection of aptamers from random DNA libraries. Biotechniques 2008, 44, 351-360.
    • (2008) Biotechniques , vol.44 , pp. 351-360
    • Pan, W.1    Xin, P.2    Clawson, G.A.3
  • 93
    • 79958283258 scopus 로고    scopus 로고
    • Identification and optimization of DNA aptamer binding regions using DNA microarrays
    • Fischer, N.O.; Tarasow, T.M. Identification and optimization of DNA aptamer binding regions using DNA microarrays. Methods Mol. Biol. 2011, 723, 57-66.
    • (2011) Methods Mol. Biol , vol.723 , pp. 57-66
    • Fischer, N.O.1    Tarasow, T.M.2
  • 94
    • 83255193503 scopus 로고    scopus 로고
    • Aptamer selection by high-throughput sequencing and informatic analysis
    • Hoon, S.; Zhou, B.; Janda, K.D.; Brenner, S.; Scolnick, J. Aptamer selection by high-throughput sequencing and informatic analysis. Biotechniques 2011, 51, 413-416.
    • (2011) Biotechniques , vol.51 , pp. 413-416
    • Hoon, S.1    Zhou, B.2    Janda, K.D.3    Brenner, S.4    Scolnick, J.5
  • 95
    • 77949531492 scopus 로고    scopus 로고
    • Monitoring genomic sequences during SELEX using high-throughput sequencing: Neutral SELEX
    • Zimmermann, B.; Gesell, T.; Chen, D.; Lorenz, C.; Schroeder, R. Monitoring genomic sequences during SELEX using high-throughput sequencing: Neutral SELEX. PLoS One 2010, 5, e9169.
    • (2010) PLoS One , vol.9169 , pp. 5
    • Zimmermann, B.1    Gesell, T.2    Chen, D.3    Lorenz, C.4    Schroeder, R.5
  • 97
    • 33846611331 scopus 로고    scopus 로고
    • Non-SELEX: Selection of aptamers without intermediate amplification of candidate oligonucleotides
    • Berezovski, M.V.; Musheev, M.U.; Drabovich, A.P.; Jitkova, J.V.; Krylov, S.N. Non-SELEX: Selection of aptamers without intermediate amplification of candidate oligonucleotides. Nat. Protoc. 2006, 1, 1359-1369.
    • (2006) Nat. Protoc , vol.1 , pp. 1359-1369
    • Berezovski, M.V.1    Musheev, M.U.2    Drabovich, A.P.3    Jitkova, J.V.4    Krylov, S.N.5
  • 99
    • 77952294160 scopus 로고    scopus 로고
    • Integrated microfluidic system for rapid screening of CRP aptamers utilizing systematic evolution of ligands by exponential enrichment (SELEX)
    • Huang, C.J.; Lin, H.I.; Shiesh, S.C.; Lee, G.B. Integrated microfluidic system for rapid screening of CRP aptamers utilizing systematic evolution of ligands by exponential enrichment (SELEX). Biosens. Bioelectron. 2010, 25, 1761-1766.
    • (2010) Biosens. Bioelectron , vol.25 , pp. 1761-1766
    • Huang, C.J.1    Lin, H.I.2    Shiesh, S.C.3    Lee, G.B.4


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