Studies of the binding mechanism between aptamers and thrombin by circular dichroism, surface plasmon resonance and isothermal titration calorimetry

Colloids and Surfaces B: Biointerfaces

Volumn 88, Issue 2, 2011, Pages 552-558

  Lin, Po Hsun ^a   Chen, Ren Hao ^a   Lee, Chung Han ^a   Chang, Yung ^b   Chen, Chien Sheng ^a   Chen, Wen Yih ^a  

^a NATIONAL CENTRAL UNIVERSITY   (Taiwan)

^b CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

Aptamer; Binding mechanism; Thrombin

Indexed keywords

APTAMERS; BINDING MECHANISMS; DUPLEX STRUCTURES; EXOSITES; G-QUADRUPLEX STRUCTURE; G-QUADRUPLEXES; HEPARIN-BINDING SITE; HUMAN BLOODS; HYDROPHOBIC EFFECT; ISOTHERMAL TITRATION CALORIMETRY; KINETICS AND THERMODYNAMICS; NON-SPECIFIC INTERACTIONS; SERINE PROTEASE; THROMBIN;

AMINO ACIDS; CALORIMETRY; DICHROISM; HYDROPHOBICITY; PLASMONS; POLYSACCHARIDES; THERMODYNAMICS; TITRATION;

SURFACE PLASMON RESONANCE;

APTAMER; FIBRINOGEN; HEPARIN; THROMBIN;

ARTICLE; BINDING KINETICS; BINDING SITE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONTROLLED STUDY; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

APTAMERS, NUCLEOTIDE; CALORIMETRY; CIRCULAR DICHROISM; FIBRINOGEN; G-QUADRUPLEXES; HEPARIN; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; SURFACE PLASMON RESONANCE; THROMBIN;

EID: 80052921815     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2011.07.032     Document Type: Article

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