Influence of race and age on aqueous humor levels of transforming growth factor-beta 2 in glaucomatous and nonglaucomatous eyes

Journal of Ocular Pharmacology and Therapeutics

Volumn 27, Issue 5, 2011, Pages 477-480

  Trivedi, Rupal H ^a   Nutaitis, Matthew ^a   Vroman, David ^a   Crosson, Craig E ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA2;

ADULT; AFRICAN AMERICAN; AGE; AGED; ANALYTICAL PARAMETERS; ARTICLE; CATARACT EXTRACTION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; EUROPEAN AMERICAN; FEMALE; GLAUCOMA; GLAUCOMA SURGERY; HUMAN; MAJOR CLINICAL STUDY; MALE; RACE; TRANSFORMING GROWTH FACTOR BETA2 AQUEOUS HUMOR LEVEL;

ADULT; AFRICAN AMERICANS; AGE FACTORS; AGED; AGED, 80 AND OVER; AQUEOUS HUMOR; CATARACT; ENZYME-LINKED IMMUNOSORBENT ASSAY; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLAUCOMA, OPEN-ANGLE; HUMANS; MALE; MIDDLE AGED; TRANSFORMING GROWTH FACTOR BETA2;

EID: 80054865277     PISSN: 10807683     EISSN: 15577732     Source Type: Journal    
DOI: 10.1089/jop.2010.0100     Document Type: Article

References (17)

1. Friedman, D.S., Wolfs, R.C., O'Colmain, B.J., Klein, B.E., Taylor, H.R., West, S., Leske, M.C., Mitchell, P., Congdon, N., Kempen, J.; and Eye Diseases Prevalence Research Group.Prevalence of open-angle glaucoma among adults in the United States. Arch. Ophthalmol.122:532-538, 2004. (Pubitemid 38456289)
2. de Voogd, S., Ikram, M.K., Wolfs, R.C., Jansonius, N.M., Witteman, J.C., Hofman, A., and de Jong, P.T. Is diabetes mellitus a risk factor for open-angle glaucoma? The Rotterdam Study. Ophthalmology 113:1827-1831, 2006. (Pubitemid 44442444)
3. Leske, M.C., Wu, S.Y., Hennis, A., Honkanen, R., Nemesure, B.; and BESs Study Group.Risk factors for incident openangle glaucoma: The Barbados Eye Studies. Ophthalmology 115:85-93, 2008. (Pubitemid 350309410)
4. Ederer, F., Gaasterland, D.A., Dally, L.G., Kim, J., Van- Veldhuisen, P.C., Blackwell, B., Prum, B., Shafranov, G., Allen, R.C., Beck, A.; and AGIS Investigators. The Advanced Glaucoma Intervention Study (AGIS): 13. Comparison of treatment outcomes within race: 10-year results. Ophthalmology 111:651-664, 2004.
5. Kang, J.S., Liu, C., and Derynck, R. New regulatory mechanisms of TGF-beta receptor function. Trends Cell. Biol. 19: 385-394, 2009.
6. Jampel, H.D., Roche, N., Stark, W.J., and Roberts, A.B. Transforming growth factor-beta in human aqueous humor. Curr. Eye Res. 9:963-969, 1990. (Pubitemid 20372121)
7. Cousins, S.W., McCabe, M.M., Danielpour, D., and Streilein, J.W. Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor. Invest. Ophthalmol. Vis. Sci. 32:2201-2211, 1991.
8. Tripathi, R.C., Chan, W.F., Li, J., and Tripathi, B.J. Trabecular cells express the TGF-beta 2 gene and secrete the cytokine. ExEye Res. 58:523-528, 1994. (Pubitemid 24249761)
9. Tripathi, R.C., Li, J., Chan, W.F., and Tripathi, B.J. Aqueous humor in glaucomatous eyes contains an increased level of TGF-beta 2. ExEye Res. 59:723-727, 1994.
10. Pasquale, L.R., Dorman-Pease, M.E., Lutty, G.A., Quigley, H.A., and Jampel, H.D. Immunolocalization of TGF-beta 1, TGF-beta 2, and TGF-beta 3 in the anterior segment of the human eye. Invest. Ophthalmol. Vis. Sci. 34:23-30, 1993. (Pubitemid 23045098)
11. Streilein, J.W. Immunoregulatory mechanisms of the eye. Prog. Retin. Eye Res. 18:357-370, 1999. (Pubitemid 29092611)
12. Picht, G., Welge-Luessen, U., Grehn, F., and Lütjen-Drecoll, E. Transforming growth factor beta 2 levels in the aqueous humor in different types of glaucoma and the relation to filtering bleb development. Graefes Arch. Clin. ExOphthalmol.239:199-207, 2001. (Pubitemid 32422026)
13. Yamamoto, N., Itonaga, K., Marunouchi, T., and Majima, K. Concentration of transforming growth factor beta2 in aqueous humor. Ophthalmic Res. 37:29-33, 2005. (Pubitemid 40663231)
14. Fuchshofer, R., Stephan, D.A., Russell, P., and Tamm, E.R. Gene expression profiling of TGFbeta2- and/or BMP7- treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling. ExEye Res. 88:1020-1032, 2009.
15. Gottanka, J., Chan, D., Eichhorn, M., Lütjen-Drecoll, E., and Ethier, C.R. Effects of TGF-beta2 in perfused human eyes. Invest. Ophthalmol. Vis. Sci. 45:153-158, 2004. (Pubitemid 38055681)
16. Shepard, A.R., Millar, J.C., Pang, I.H., Jacobson, N., Wang, W.H., and Clark, A.F. Adenoviral gene transfer of active human transforming growth factor-{beta}2 elevates intraocular pressure and reduces outflow facility in rodent eyes. Invest. Ophthalmol. Vis. Sci. 51:2067-2076, 2010.
17. Gaasterland, D., Kupfer, C., Milton, R., Ross, K., McCain, L., and MacLellan, H. Studies of aqueous humour dynamics in man. VI. Effect of age upon parameters of intraocular pressure in normal human eyes. ExEye Res. 26:651-656, 1978. (Pubitemid 8359035)