Role of A 2B adenosine receptors in regulation of paracrine functions of stem cell antigen 1-positive cardiac stromal cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 341, Issue 3, 2012, Pages 764-774

  Ryzhov, Sergey ^a   Goldstein, Anna E ^a   Novitskiy, Sergey V ^a   Blackburn, Michael R ^b   Biaggioni, Italo ^a   Feoktistov, Igor ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A2B RECEPTOR; CXCL1 CHEMOKINE; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; STEM CELL ANTIGEN 1; VASCULOTROPIN; ADENOSINE; ADENOSINE DEAMINASE; CD31 ANTIGEN; CXCL1 PROTEIN, MOUSE; LY ANTIGEN; LY6A PROTEIN, MOUSE; MEMBRANE PROTEIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARDIAC STROMAL CELL; CELL COUNT; CELL FUNCTION; CELL GROWTH; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENDOTHELIUM CELL; GENE EXPRESSION; HEART INFARCTION; HEART MUSCLE CELL; IMMUNOPHENOTYPING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STROMA CELL; UPREGULATION; AGAMMAGLOBULINEMIA; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; FEMALE; HEART MUSCLE; MALE; MESENCHYMAL STROMA CELL; METABOLISM; MOUSE; MOUSE MUTANT; PARACRINE SIGNALING; PHYSIOLOGY; SEVERE COMBINED IMMUNODEFICIENCY; STEM CELL; TRANSGENIC MOUSE;

ADENOSINE; ADENOSINE DEAMINASE; AGAMMAGLOBULINEMIA; ANIMALS; ANTIGENS, CD31; ANTIGENS, LY; CELLS, CULTURED; CHEMOKINE CXCL1; FEMALE; INTERLEUKIN-6; MALE; MEMBRANE PROTEINS; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYOCARDIAL INFARCTION; MYOCARDIUM; PARACRINE COMMUNICATION; RECEPTOR, ADENOSINE A2B; RNA, MESSENGER; SEVERE COMBINED IMMUNODEFICIENCY; STEM CELLS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84861566855     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.190835     Document Type: Article

References (53)

1. Adair TH (2005) Growth regulation of the vascular system: an emerging role for adenosine. Am J Physiol Regul Integr Comp Physiol 289:R283-R296.
2. Aisagbonhi O, Rai M, Ryzhov S, Atria N, Feoktistov I, and Hatzopoulos AK (2011) Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition. Dis Model Mech 4:469-483.
3. Alfaro MP, Pagni M, Vincent A, Atkinson J, Hill MF, Cates J, Davidson JM, Rottman J, Lee E, and Young PP (2008) The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair. Proc Natl Acad Sci USA 105:18366-18371.
4. Anjos-Afonso F and Bonnet D (2008) Isolation, culture, and differentiation potential of mouse marrow stromal cells. Curr Protoc Stem Cell Biol Unit 2B.3.
5. Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, et al. (2003) Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114:763-776. (Pubitemid 37186770)
6. Blackburn MR, Aldrich M, Volmer JB, Chen W, Zhong H, Kelly S, Hershfield MS, Datta SK, and Kellems RE (2000) The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities. J Biol Chem 275:32114-32121.
7. Blackburn MR, Datta SK, and Kellems RE (1998) Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency. J Biol Chem 273:5093-5100. (Pubitemid 28108669)
8. 2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity. J Med Chem 52:3994-4006.
9. Chimenti I, Smith RR, Li TS, Gerstenblith G, Messina E, Giacomello A, and Marbán E (2010) Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res 106:971-980.
10. 2A adenosine receptors and C/EBPßare crucially required for IL-10 production by macrophages exposed to Escherichia coli. Blood 110:2685-2695.
11. Dominici M, Le Blanc K, Mueller I, Slaper-Cortenbach I, Marini FC, Krause DS, Deans RJ, Keating A, Prockop DJ, and Horwitz EM (2006) Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8:315-317. (Pubitemid 44269669)
12. 2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest 96:1979-1986.
13. 2B receptor-mediated interleukin-8 production in human mast cells. Mol Pharmacol 55:726-734.
14. 2B receptors in angiogenic factor regulation. Circ Res 90:531-538.
15. 3 adenosine receptors. Circ Res 92:485-492.
16. Ferrara N, Gerber HP, and LeCouter J (2003) The biology of VEGF and its receptors. Nat Med 9:669-676. (Pubitemid 36749215)
17. Fredholm BB (2007) Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ 14:1315-1323.
18. Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, and Linden J (2001) International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53:527-552. (Pubitemid 33136237)
19. Gnecchi M, Zhang Z, Ni A, and Dzau VJ (2008) Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res 103:1204-1219.
20. Grant MB, Davis MI, Caballero S, Feoktistov I, Biaggioni I, and Belardinelli L (2001) Proliferation, migration, and ERK activation in human retinal endothelial cells through A2B adenosine receptor stimulation. Invest Ophthalmol Vis Sci 42:2068-2073. (Pubitemid 32726041)
21. Grant MB, Tarnuzzer RW, Caballero S, Ozeck MJ, Davis MI, Spoerri PE, Feoktistov I, Biaggioni I, Shryock JC, and Belardinelli L (1999) Adenosine receptor activation induces vascular endothelial growth factor in human retinal endothelial cells. Circ Res 85:699-706. (Pubitemid 29480810)
22. Hernández-Rodríguez J, Segarra M, Vilardell C, Sánchez M, García-Martínez A, Esteban MJ, Grau JM, Urbano-Márquez A, Colomer D, Kleinman HK, et al. (2003) Elevated production of interleukin-6 is associated with a lower incidence of disease-related ischemic events in patients with giant-cell arteritis: angiogenic activity of interleukin-6 as a potential protective mechanism. Circulation 107:2428-2434. (Pubitemid 36605224)
23. Holmes C and Stanford WL (2007) Concise review: stem cell antigen-1: expression, function, and enigma. Stem Cells 25:1339-1347. (Pubitemid 47106000)
24. +cardiac stem cells mediate acute cardioprotection via paracrine factor SDF-1 following myocardial ischemia/reperfusion. PLoS One 6:e29246.
25. Ieronimakis N, Balasundaram G, and Reyes M (2008) Direct isolation, culture and transplant of mouse skeletal muscle derived endothelial cells with angiogenic potential. PLoS One 3:e0001753.
26. Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals, 7th ed, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington, DC.
27. b-tsA58 transgenic mouse. Proc Natl Acad Sci USA 88:5096-5100.
28. Kinnaird T, Stabile E, Burnett MS, Lee CW, Barr S, Fuchs S, and Epstein SE (2004) Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 94:678-685. (Pubitemid 38387752)
29. - cardiac side population cells in a murine myocardial ischemic model. Int J Cardiol 138:40-49.
30. Lidington EA, Rao RM, Marelli-Berg FM, Jat PS, Haskard DO, and Mason JC (2002) Conditional immortalization of growth factor-responsive cardiac endothelial cells from H-2Kb-tsA58 mice. Am J Physiol Cell Physiol 282:C67-C74. (Pubitemid 34662553)
31. qin human embryonic kidney 293 cells and HMC-1 mast cells. Mol Pharmacol 56:705-713.
32. Martin BJ, McClanahan TB, Van Wylen DG, and Gallagher KP (1997) Effects of ischemia, preconditioning, and adenosine deaminase inhibition on interstitial adenosine levels and infarct size. Basic Res Cardiol 92:240-251. (Pubitemid 27443298)
33. Martin CM, Ferdous A, Gallardo T, Humphries C, Sadek H, Caprioli A, Garcia JA, Szweda LI, Garry MG, and Garry DJ (2008) Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cells. Circ Res 102:1075-1081. (Pubitemid 351667861)
34. Matsuura K, Honda A, Nagai T, Fukushima N, Iwanaga K, Tokunaga M, Shimizu T, Okano T, Kasanuki H, Hagiwara N, et al. (2009) Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice. J Clin Invest 119:2204-2217.
35. Matsuura K, Nagai T, Nishigaki N, Oyama T, Nishi J, Wada H, Sano M, Toko H, Akazawa H, Sato T, et al. (2004) Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes. J Biol Chem 279:11384-11391. (Pubitemid 38401637)
36. Maxeiner H, Krehbiehl N, Müller A, Woitasky N, Akintürk H, Müller M, Weigand MA, Abdallah Y, Kasseckert S, Schreckenberg R, et al. (2010) New insights into paracrine mechanisms of human cardiac progenitor cells. Eur J Heart Fail 12:730-737.
37. Messina E, De Angelis L, Frati G, Morrone S, Chimenti S, Fiordaliso F, Salio M, Battaglia M, Latronico MV, Coletta M, et al. (2004) Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 95:911-921. (Pubitemid 39435006)
38. Mohri T, Fujio Y, Obana M, Iwakura T, Matsuda K, Maeda M, and Azuma J (2009) Signals through glycoprotein 130 regulate the endothelial differentiation of cardiac stem cells. Arterioscler Thromb Vasc Biol 29:754-760.
39. + cardiac side population cells exhibit functional cardiomyogenic differentiation. Circ Res 97:52-61.
40. 2B adenosine receptors in human mast cells. Mol Pharmacol 70:727-735.
41. Ryzhov S, McCaleb JL, Goldstein AE, Biaggioni I, and Feoktistov I (2007) Role of adenosine receptors in the regulation of angiogenic factors and neovascularization in hypoxia. J Pharmacol Exp Ther 382:565-572. (Pubitemid 46147935)
42. 2B adenosine receptors promote carcinoma growth. Neoplasia 10:987-995.
43. 2B adenosine receptor in stimulation of adenylate cyclase, phospholipase Cβ, and interleukin-8. Purinergic Signal 5:289-298.
44. 2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells. J Immunol 180:7212-7220.
45. Smits AM, van Vliet P, Metz CH, Korfage T, Sluijter JP, Doevendans PA, and Goumans MJ (2009) Human cardiomyocyte progenitor cells differentiate into functional mature cardiomyocytes: an in vitro model for studying human cardiac physiology and pathophysiology. Nat Protoc 4:232-243.
46. Strieter RM, Polverini PJ, Kunkel SL, Arenberg DA, Burdick MD, Kasper J, Dzuiba J, Van Damme J, Walz A, and Marriott D (1995) The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J Biol Chem 270:27348-27357.
47. Takahashi M, Li TS, Suzuki R, Kobayashi T, Ito H, Ikeda Y, Matsuzaki M, and Hamano K (2006) Cytokines produced by bone marrow cells can contribute to functional improvement of the infarcted heart by protecting cardiomyocytes from ischemic injury. Am J Physiol Heart Circ Physiol 291:H886-H893. (Pubitemid 44175098)
48. Tateishi K, Ashihara E, Takehara N, Nomura T, Honsho S, Nakagami T, Morikawa S, Takahashi T, Ueyama T, Matsubara H, et al. (2007) Clonally amplified cardiac stem cells are regulated by Sca-1 signaling for efficient cardiovascular regeneration. J Cell Sci 120:1791-1800. (Pubitemid 46930417)
49. Uemura R, Xu M, Ahmad N, and Ashraf M (2006) Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling. Circ Res 98:1414-1421. (Pubitemid 43948066)
50. - cardiac progenitor cell population in postinfarction left ventricular remodeling. Stem Cells 24:1779-1788.
51. 1receptor deficiency in normoxic and ischaemic mouse hearts. Cardiovasc Res 71:79-87.
52. 2B adenosine receptors in the U87MG tumor cells. Drug Dev Res 58:405-411.
53. 2a adenosine receptor antagonist. J Pharmacol Exp Ther 276:398-404.