-
1
-
-
33947489961
-
Isolation structure and partial synthesis of an active constituent of hashish
-
Gaoni, Y. & Mechoulam, R. Isolation, structure and partial synthesis of an active constituent of hashish. J. Am. Chem. Soc. 86, 1646-1647 (1964).
-
(1964)
J. Am. Chem. Soc.
, vol.86
, pp. 1646-1647
-
-
Gaoni, Y.1
Mechoulam, R.2
-
2
-
-
38349158960
-
The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin
-
Pertwee, R. G. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin. Br. J. Pharmacol. 153, 199-215 (2008).
-
(2008)
Br. J. Pharmacol.
, vol.153
, pp. 199-215
-
-
Pertwee, R.G.1
-
3
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane, W. A. et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258, 1946-1949 (1992). (Pubitemid 23026736)
-
(1992)
Science
, vol.258
, Issue.5090
, pp. 1946-1949
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
Pertwee, R.G.4
Stevenson, L.A.5
Griffin, G.6
Gibson, D.7
Mandelbaum, A.8
Etinger, A.9
Mechoulam, R.10
-
4
-
-
0029012014
-
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
-
Mechoulam, R. et al. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem. Pharmacol. 50, 83-90 (1995).
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 83-90
-
-
Mechoulam, R.1
-
5
-
-
0028970517
-
2-Arachidonoylglycerol: A possible endogenous cannabinoid receptor ligand in brain
-
Sugiura, T. et al. 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. Biochem. Biophys. Res. Commun. 215, 89-97 (1995).
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.215
, pp. 89-97
-
-
Sugiura, T.1
-
6
-
-
78650120798
-
International union of basic and clinical pharmacology. LXXIX. Cannabinoid receptors and their ligands: Beyond CB1 and CB2
-
Pertwee, R. G. et al. International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2. Pharmacol. Rev. 62, 588-631 (2010).
-
(2010)
Pharmacol. Rev.
, vol.62
, pp. 588-631
-
-
Pertwee, R.G.1
-
7
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda, L. A., Lolait, S. J., Brownstein, M. J., Young, A. C. & Bonner, T. I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561-564 (1990).
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
8
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
DOI 10.1038/365061a0
-
Munro, S., Thomas, K. L. & Abu-Shaar, M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 365, 61-65 (1993). (Pubitemid 23305569)
-
(1993)
Nature
, vol.365
, Issue.6441
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
9
-
-
33845959991
-
2 receptor: A new target for controlling neural cell survival?
-
DOI 10.1016/j.tips.2006.11.001, PII S0165614706002677
-
Fernandez-Ruiz, J. et al. Cannabinoid CB2 receptor: a new target for controlling neural cell survival? Trends Pharmacol. Sci. 28, 39-45 (2007). (Pubitemid 46038536)
-
(2007)
Trends in Pharmacological Sciences
, vol.28
, Issue.1
, pp. 39-45
-
-
Fernandez-Ruiz, J.1
Romero, J.2
Velasco, G.3
Tolon, R.M.4
Ramos, J.A.5
Guzman, M.6
-
10
-
-
77952623444
-
CB2: A cannabinoid receptor with an identity crisis
-
Atwood, B. K. & Mackie, K. CB2: a cannabinoid receptor with an identity crisis. Br. J. Pharmacol. 160, 467-479 (2010).
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 467-479
-
-
Atwood, B.K.1
MacKie, K.2
-
11
-
-
33745929641
-
9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme
-
DOI 10.1038/sj.bjc.6603236, PII 6603236
-
Guzman, M. et al. A pilot clinical study of Δ9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Br. J. Cancer 95, 197-203 (2006). (Pubitemid 44050919)
-
(2006)
British Journal of Cancer
, vol.95
, Issue.2
, pp. 197-203
-
-
Guzman, M.1
Duarte, M.J.2
Blazquez, C.3
Ravina, J.4
Rosa, M.C.5
Galve-Roperh, I.6
Sanchez, C.7
Velasco, G.8
Gonzalez-Feria, L.9
-
12
-
-
39049104489
-
Cannabinoids for cancer treatment: Progress and promise
-
DOI 10.1158/0008-5472.CAN-07-2785
-
Sarfaraz, S., Adhami, V. M., Syed, D. N., Afaq, F. & Mukhtar, H. Cannabinoids for cancer treatment: progress and promise. Cancer Res. 68, 339-342 (2008). (Pubitemid 351380057)
-
(2008)
Cancer Research
, vol.68
, Issue.2
, pp. 339-342
-
-
Sarfaraz, S.1
Adhami, V.M.2
Syed, D.N.3
Afaq, F.4
Mukhtar, H.5
-
13
-
-
51349141952
-
Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
-
Katona, I. & Freund, T. F. Endocannabinoid signaling as a synaptic circuit breaker in neurological disease. Nature Med. 14, 923-930 (2008).
-
(2008)
Nature Med.
, vol.14
, pp. 923-930
-
-
Katona, I.1
Freund, T.F.2
-
14
-
-
33748703859
-
The endocannabinoid system as an emerging target of pharmacotherapy
-
DOI 10.1124/pr.58.3.2
-
Pacher, P., Batkai, S. & Kunos, G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol. Rev. 58, 389-462 (2006). (Pubitemid 44394908)
-
(2006)
Pharmacological Reviews
, vol.58
, Issue.3
, pp. 389-462
-
-
Pacher, P.1
Batkai, S.2
Kunos, G.3
-
15
-
-
65449146377
-
Emerging strategies for exploiting cannabinoid receptor agonists as medicines
-
Pertwee, R. G. Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br. J. Pharmacol. 156, 397-411 (2009).
-
(2009)
Br. J. Pharmacol.
, vol.156
, pp. 397-411
-
-
Pertwee, R.G.1
-
16
-
-
0142166330
-
Cannabinoids: Potential anticancer agents
-
Guzman, M. Cannabinoids: potential anticancer agents. Nature Rev. Cancer 3, 745-755 (2003). (Pubitemid 37328813)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.10
, pp. 745-755
-
-
Guzman, M.1
-
17
-
-
77952532122
-
The expression level of CB1 and CB2 receptors determines their efficacy at inducing apoptosis in astrocytomas
-
Cudaback, E., Marrs, W., Moeller, T. & Stella, N. The expression level of CB1 and CB2 receptors determines their efficacy at inducing apoptosis in astrocytomas. PLoS ONE 5, e8702 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Cudaback, E.1
Marrs, W.2
Moeller, T.3
Stella, N.4
-
18
-
-
1542510624
-
Cannabinoids Induce Cancer Cell Proliferation via Tumor Necrosis Factor α-Converting Enzyme (TACE/ADAM17)-Mediated Transactivation of the Epidermal Growth Factor Receptor
-
DOI 10.1158/0008-5472.CAN-03-3720
-
Hart, S., Fischer, O. M. & Ullrich, A. Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor. Cancer Res. 64, 1943-1950 (2004). (Pubitemid 38339438)
-
(2004)
Cancer Research
, vol.64
, Issue.6
, pp. 1943-1950
-
-
Hart, S.1
Fischer, O.M.2
Ullrich, A.3
-
19
-
-
14844362003
-
Δ-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response
-
McKallip, R. J., Nagarkatti, M. & Nagarkatti, P. S. Δ9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. J. Immunol. 174, 3281-3289 (2005). (Pubitemid 40354031)
-
(2005)
Journal of Immunology
, vol.174
, Issue.6
, pp. 3281-3289
-
-
McKallip, R.J.1
Nagarkatti, M.2
Nagarkatti, P.S.3
-
20
-
-
0034235808
-
Δ-9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor- mediated, cytokine-dependent pathway
-
Zhu, L. X. et al. Δ9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway. J. Immunol. 165, 373-380 (2000). (Pubitemid 30429529)
-
(2000)
Journal of Immunology
, vol.165
, Issue.1
, pp. 373-380
-
-
Zhu, L.X.1
Sharma, S.2
Stolina, M.3
Gardner, B.4
Roth, M.D.5
Tashkin, D.P.6
Dubinett, S.M.7
-
21
-
-
79951590481
-
Update on the endocannabinoid system as an anticancer target
-
Malfitano, A. M. et al. Update on the endocannabinoid system as an anticancer target. Expert Opin. Ther. Targets. 15, 297-308 (2011).
-
(2011)
Expert Opin. Ther. Targets.
, vol.15
, pp. 297-308
-
-
Malfitano, A.M.1
-
22
-
-
33746125474
-
9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation
-
DOI 10.1158/0008-5472.CAN-05-4566
-
Caffarel, M. M., Sarrio, D., Palacios, J., Guzman, M. & Sanchez, C. Δ9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation. Cancer Res. 66, 6615-6621 (2006). (Pubitemid 44085617)
-
(2006)
Cancer Research
, vol.66
, Issue.13
, pp. 6615-6621
-
-
Caffarel, M.M.1
Sarrio, D.2
Palacios, J.3
Guzman, M.4
Sanchez, C.5
-
23
-
-
0035422139
-
2 cannabinoid receptor
-
Sanchez, C. et al. Inhibition of glioma growth in vivo by selective activation of the CB2 cannabinoid receptor. Cancer Res. 61, 5784-5789 (2001). (Pubitemid 32769095)
-
(2001)
Cancer Research
, vol.61
, Issue.15
, pp. 5784-5789
-
-
Sanchez, C.1
De Ceballos, M.L.2
Gomez Del Pulgar, T.3
Rueda, D.4
Corbacho, C.5
Velasco, G.6
Galve-Roperh, I.7
Huffman, J.W.8
Ramon Cajal, S.9
Guzman, M.10
-
24
-
-
73149109062
-
Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis
-
Nomura, D. K. et al. Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis. Cell 140, 49-61 (2010).
-
(2010)
Cell
, vol.140
, pp. 49-61
-
-
Nomura, D.K.1
-
25
-
-
77957906635
-
Fatty acid amide hydrolase in prostate cancer: Association with disease severity and outcome. CB1 receptor expression and regulation by IL-4
-
Thors, L. et al. Fatty acid amide hydrolase in prostate cancer: association with disease severity and outcome, CB1 receptor expression and regulation by IL-4. PLoS ONE 5, e12275 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Thors, L.1
-
26
-
-
45549095987
-
The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer development
-
Zheng, D. et al. The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer development. Cancer Res. 68, 3992-3998 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 3992-3998
-
-
Zheng, D.1
-
27
-
-
0036141517
-
Leukemic predisposition of pSca-1/Cb2 transgenic mice
-
DOI 10.1016/S0301-472X(01)00779-2, PII S0301472X01007792
-
Joosten, M. et al. Leukemic predisposition of pSca-1/Cb2 transgenic mice. Exp. Hematol. 30, 142-149 (2002). (Pubitemid 34081225)
-
(2002)
Experimental Hematology
, vol.30
, Issue.2
, pp. 142-149
-
-
Joosten, M.1
Valk, P.J.M.2
Jorda, M.A.3
Vankan-Berkhoudt, Y.4
Verbakel, S.5
Van Den Broek, M.6
Beijen, A.7
Lowenberg, B.8
Delwel, R.9
-
28
-
-
51049102995
-
Loss of cannabinoid receptor 1 accelerates intestinal tumor growth
-
Wang, D. et al. Loss of cannabinoid receptor 1 accelerates intestinal tumor growth. Cancer Res. 68, 6468-6476 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 6468-6476
-
-
Wang, D.1
-
29
-
-
38149055682
-
Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon
-
Izzo, A. A. et al. Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. J. Mol. Med. (Berl.) 86, 89-98 (2008).
-
(2008)
J. Mol. Med. (Berl.)
, vol.86
, pp. 89-98
-
-
Izzo, A.A.1
-
30
-
-
4143086166
-
Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas
-
DOI 10.1158/0008-5472.CAN-03-3927
-
Blazquez, C. et al. Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. Cancer Res. 64, 5617-5623 (2004). (Pubitemid 39095557)
-
(2004)
Cancer Research
, vol.64
, Issue.16
, pp. 5617-5623
-
-
Blazquez, C.1
Gonzalez-Feria, L.2
Alvarez, L.3
Haro, A.4
Casanova, M.L.5
Guzman, M.6
-
31
-
-
17344380844
-
Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
-
DOI 10.1038/73171
-
Galve-Roperh, I. et al. Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nature Med. 6, 313-319 (2000). (Pubitemid 30148624)
-
(2000)
Nature Medicine
, vol.6
, Issue.3
, pp. 313-319
-
-
Galve-Roperh, I.1
Sanchez, C.2
Cortes, M.L.3
Del Pulgar, T.G.4
Izquierdo, M.5
Guzman, M.6
-
32
-
-
0036534724
-
De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis
-
DOI 10.1042/0264-6021:3630183
-
Gomez del Pulgar, T., Velasco, G., Sanchez, C., Haro, A. & Guzman, M. De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis. Biochem. J. 363, 183-188 (2002). (Pubitemid 34280625)
-
(2002)
Biochemical Journal
, vol.363
, Issue.1
, pp. 183-188
-
-
Del Pulgar, T.G.1
Velasco, G.2
Sanchez, C.3
Haro, A.4
Guzman, M.5
-
33
-
-
33645763253
-
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells
-
Carracedo, A. et al. The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells. Cancer Cell 9, 301-312 (2006).
-
(2006)
Cancer Cell
, vol.9
, pp. 301-312
-
-
Carracedo, A.1
-
34
-
-
0035951881
-
Human p8 is a HMG-I/Y-like protein with DNA binding activity enhanced by phosphorylation
-
Encinar, J. A. et al. Human p8 is a HMG-I/Y-like protein with DNA binding activity enhanced by phosphorylation. J. Biol. Chem. 276, 2742-2751 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2742-2751
-
-
Encinar, J.A.1
-
35
-
-
22244446505
-
The mammalian unfolded protein response
-
DOI 10.1146/annurev.biochem.73.011303.074134
-
Schroder, M. & Kaufman, R. J. The mammalian unfolded protein response. Annu. Rev. Biochem. 74, 739-789 (2005). (Pubitemid 40995523)
-
(2005)
Annual Review of Biochemistry
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
36
-
-
77955947900
-
Linking ER stress to autophagy: Potential implications for cancer therapy
-
930509
-
Verfaillie, T., Salazar, M., Velasco, G. & Agostinis, P. Linking ER stress to autophagy: potential implications for cancer therapy. Int. J. Cell Biol. 2010, 930509 (2010).
-
(2010)
Int. J. Cell Biol.
-
-
Verfaillie, T.1
Salazar, M.2
Velasco, G.3
Agostinis, P.4
-
37
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
DOI 10.1038/nature06639, PII NATURE06639
-
Mizushima, N., Levine, B., Cuervo, A. M. & Klionsky, D. J. Autophagy fights disease through cellular self-digestion. Nature 451, 1069-1075 (2008). (Pubitemid 351317450)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
38
-
-
67549142261
-
Life and death partners: Apoptosis, autophagy and the cross-talk between them
-
Eisenberg-Lerner, A., Bialik, S., Simon, H. U. & Kimchi, A. Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ. 16, 966-975 (2009).
-
(2009)
Cell Death Differ.
, vol.16
, pp. 966-975
-
-
Eisenberg-Lerner, A.1
Bialik, S.2
Simon, H.U.3
Kimchi, A.4
-
39
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
Salazar, M. et al. Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J. Clin. Invest. 119, 1359-1372 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
-
40
-
-
79958809001
-
Anti-tumoral action of cannabinoids on hepatocellular carcinoma: Role of AMPK-dependent activation of autophagy
-
Vara, D. et al. Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy. Cell Death Differ. 18, 1099-1111 (2011).
-
(2011)
Cell Death Differ.
, vol.18
, pp. 1099-1111
-
-
Vara, D.1
-
41
-
-
33746138649
-
Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes
-
DOI 10.1158/0008-5472.CAN-06-0169
-
Carracedo, A. et al. Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes. Cancer Res. 66, 6748-6755 (2006). (Pubitemid 44085633)
-
(2006)
Cancer Research
, vol.66
, Issue.13
, pp. 6748-6755
-
-
Carracedo, A.1
Gironella, M.2
Lorente, M.3
Garcia, S.4
Guzman, M.5
Velasco, G.6
Iovanna, J.L.7
-
42
-
-
33845627660
-
Cannabinoid receptors as novel targets for the treatment of melanoma
-
Blazquez, C. et al. Cannabinoid receptors as novel targets for the treatment of melanoma. FASEB J. 20, 2633-2635 (2006).
-
(2006)
FASEB J
, vol.20
, pp. 2633-2635
-
-
Blazquez, C.1
-
43
-
-
33845973763
-
1 cell cycle arrest
-
DOI 10.1074/jbc.M603495200
-
Sarfaraz, S., Afaq, F., Adhami, V. M., Malik, A. & Mukhtar, H. Cannabinoid receptor agonist-induced apoptosis of human prostate cancer cells LNCaP proceeds through sustained activation of ERK1/2 leading to G1 cell cycle arrest. J. Biol. Chem. 281, 39480-39491 (2006). (Pubitemid 46041908)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.51
, pp. 39480-39491
-
-
Sarfaraz, S.1
Afaq, F.2
Adhami, V.M.3
Malik, A.4
Mukhtar, H.5
-
44
-
-
79960336157
-
The endocannabinoid system and cancer: Therapeutic implication
-
Guindon, J. & Hohmann, A. G. The endocannabinoid system and cancer: therapeutic implication. Br. J. Pharmacol. 163, 1447-1463 (2011).
-
(2011)
Br. J. Pharmacol.
, vol.163
, pp. 1447-1463
-
-
Guindon, J.1
Hohmann, A.G.2
-
45
-
-
33747624175
-
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma
-
DOI 10.1124/jpet.106.105247
-
Ligresti, A. et al. Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma. J. Pharmacol. Exp. Ther. 318, 1375-1387 (2006). (Pubitemid 44268348)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.318
, Issue.3
, pp. 1375-1387
-
-
Ligresti, A.1
Moriello, A.S.2
Starowicz, K.3
Matias, I.4
Pisanti, S.5
De Petrocellis, L.6
Laezza, C.7
Portella, G.8
Bifulco, M.9
Di Marzo, V.10
-
46
-
-
38449109178
-
5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid
-
DOI 10.1111/j.1471-4159.2007.05073.x
-
Massi, P. et al. 5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid. J. Neurochem. 104, 1091-1100 (2008). (Pubitemid 351143654)
-
(2008)
Journal of Neurochemistry
, vol.104
, Issue.4
, pp. 1091-1100
-
-
Massi, P.1
Valenti, M.2
Vaccani, A.3
Gasperi, V.4
Perletti, G.5
Marras, E.6
Fezza, F.7
Maccarrone, M.8
Parolaro, D.9
-
47
-
-
79960115996
-
Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy
-
Shrivastava, A., Kuzontkoski, P. M., Groopman, J. E. & Prasad, A. Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy. Mol. Cancer Ther. 10, 1161-1172 (2011).
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 1161-1172
-
-
Shrivastava, A.1
Kuzontkoski, P.M.2
Groopman, J.E.3
Prasad, A.4
-
48
-
-
33748492117
-
The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells
-
DOI 10.1007/s00018-006-6156-x
-
Massi, P. et al. The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells. Cel. Mol. Life Sci. 63, 2057-2066 (2006). (Pubitemid 44359745)
-
(2006)
Cellular and Molecular Life Sciences
, vol.63
, Issue.17
, pp. 2057-2066
-
-
Massi, P.1
Vaccani, A.2
Bianchessi, S.3
Costa, B.4
Macchi, P.5
Parolaro, D.6
-
49
-
-
0037253496
-
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors
-
Casanova, M. L. et al. Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. J. Clin. Invest. 111, 43-50 (2003).
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 43-50
-
-
Casanova, M.L.1
-
50
-
-
0037365941
-
Inhibition of tumor angiogenesis by cannabinoids
-
Blazquez, C. et al. Inhibition of tumor angiogenesis by cannabinoids. FASEB J. 17, 529-531 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 529-531
-
-
Blazquez, C.1
-
51
-
-
0141594998
-
Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: Actions on signals involved in angiogenesis and metastasis
-
Portella, G. et al. Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis. FASEB J. 17, 1771-1773 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 1771-1773
-
-
Portella, G.1
-
52
-
-
34147215056
-
Antiangiogenic activity of the endocannabinoid anandamide: Correlation to its tumor-suppressor efficacy
-
DOI 10.1002/jcp.20954
-
Pisanti, S. et al. Antiangiogenic activity of the endocannabinoid anandamide: correlation to its tumor-suppressor efficacy. J. Cell Physiol. 211, 495-503 (2007). (Pubitemid 46580103)
-
(2007)
Journal of Cellular Physiology
, vol.211
, Issue.2
, pp. 495-503
-
-
Pisanti, S.1
Borselli, C.2
Oliviero, O.3
Laezza, C.4
Gazzerro, P.5
Bifulco, M.6
-
53
-
-
40949083594
-
Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression
-
DOI 10.1158/0008-5472.CAN-07-5176
-
Blazquez, C. et al. Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Cancer Res. 68, 1945-1952 (2008). (Pubitemid 351416581)
-
(2008)
Cancer Research
, vol.68
, Issue.6
, pp. 1945-1952
-
-
Blazquez, C.1
Salazar, M.2
Carracedo, A.3
Lorente, M.4
Egia, A.5
Gonzalez-Feria, L.6
Haro, A.7
Velasco, G.8
Guzman, M.9
-
54
-
-
29144447456
-
Anandamide inhibits adhesion and migration of breast cancer cells
-
DOI 10.1016/j.yexcr.2005.10.024, PII S0014482705005094
-
Grimaldi, C. et al. Anandamide inhibits adhesion and migration of breast cancer cells. Exp. Cell Res. 312, 363-373 (2006). (Pubitemid 41804104)
-
(2006)
Experimental Cell Research
, vol.312
, Issue.4
, pp. 363-373
-
-
Grimaldi, C.1
Pisanti, S.2
Laezza, C.3
Malfitano, A.M.4
Santoro, A.5
Vitale, M.6
Caruso, M.G.7
Notarnicola, M.8
Iacuzzo, I.9
Portella, G.10
Di Marzo, V.11
Bifulco, M.12
-
55
-
-
70949091684
-
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer
-
Qamri, Z. et al. Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. Mol. Cancer Ther. 8, 3117-3129 (2009).
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 3117-3129
-
-
Qamri, Z.1
-
56
-
-
38049143945
-
Δ9-tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo
-
Preet, A., Ganju, R. K. & Groopman, J. E. Δ9- tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Oncogene 27, 339-346 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 339-346
-
-
Preet, A.1
Ganju, R.K.2
Groopman, J.E.3
-
57
-
-
38049185265
-
Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1
-
DOI 10.1093/jnci/djm268
-
Ramer, R. & Hinz, B. Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1. J. Natl. Cancer Inst. 100, 59-69 (2008). (Pubitemid 351767340)
-
(2008)
Journal of the National Cancer Institute
, vol.100
, Issue.1
, pp. 59-69
-
-
Ramer, R.1
Hinz, B.2
-
58
-
-
36749015683
-
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
-
DOI 10.1158/1535-7163.MCT-07-0371
-
McAllister, S. D., Christian, R. T., Horowitz, M. P., Garcia, A. & Desprez, P. Y. Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. Mol. Cancer Ther. 6, 2921-2927 (2007). (Pubitemid 350206770)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.11
, pp. 2921-2927
-
-
McAllister, S.D.1
Christian, R.T.2
Horowitz, M.P.3
Garcia, A.4
Desprez, P.-Y.5
-
59
-
-
79960835512
-
Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis
-
McAllister, S. D. et al. Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. Breast Cancer Res. Treat. 129, 37-47 (2011).
-
(2011)
Breast Cancer Res. Treat.
, vol.129
, pp. 37-47
-
-
McAllister, S.D.1
-
60
-
-
52949118833
-
Mechanisms of control of neuron survival by the endocannabinoid system
-
Galve-Roperh, I., Aguado, T., Palazuelos, J. & Guzman, M. Mechanisms of control of neuron survival by the endocannabinoid system. Curr. Pharm. Des. 14, 2279-2288 (2008).
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 2279-2288
-
-
Galve-Roperh, I.1
Aguado, T.2
Palazuelos, J.3
Guzman, M.4
-
61
-
-
26844566936
-
Toxicity and carcinogenicity of Δ9-tetrahydrocannabinol in Fischer rats and B6C3F1 mice
-
Chan, P. C., Sills, R. C., Braun, A. G., Haseman, J. K. & Bucher, J. R. Toxicity and carcinogenicity of Δ9-tetrahydrocannabinol in Fischer rats and B6C3F1 mice. Fundam. Appl. Toxicol. 30, 109-117 (1996).
-
(1996)
Fundam. Appl. Toxicol.
, vol.30
, pp. 109-117
-
-
Chan, P.C.1
Sills, R.C.2
Braun, A.G.3
Haseman, J.K.4
Bucher, J.R.5
-
62
-
-
33846828655
-
CB2 cannabinoid receptor agonist, JWH-015, triggers apoptosis in immune cells: Potential role for CB2-selective ligands as immunosuppressive agents
-
DOI 10.1016/j.clim.2006.11.002, PII S1521661606009430
-
Lombard, C., Nagarkatti, M. & Nagarkatti, P. CB2 cannabinoid receptor agonist, JWH-015, triggers apoptosis in immune cells: potential role for CB2-selective ligands as immunosuppressive agents. Clin. Immunol. 122, 259-270 (2007). (Pubitemid 46216921)
-
(2007)
Clinical Immunology
, vol.122
, Issue.3
, pp. 259-270
-
-
Lombard, C.1
Nagarkatti, M.2
Nagarkatti, P.3
-
63
-
-
77954175124
-
Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression
-
Rieder, S. A., Chauhan, A., Singh, U., Nagarkatti, M. & Nagarkatti, P. Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. Immunobiology 215, 598-605 (2010).
-
(2010)
Immunobiology
, vol.215
, pp. 598-605
-
-
Rieder, S.A.1
Chauhan, A.2
Singh, U.3
Nagarkatti, M.4
Nagarkatti, P.5
-
64
-
-
79955865808
-
Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action
-
Lorente, M. et al. Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action. Cell Death Differ. 18, 959-973 (2011).
-
(2011)
Cell Death Differ.
, vol.18
, pp. 959-973
-
-
Lorente, M.1
-
65
-
-
60549114334
-
CB1 and CB2 cannabinoid receptors mediate different aspects of Δ9-tetrahydrocannabinol (THC)-induced T helper cell shift following immune activation by Legionella pneumophila infection
-
Newton, C. A., Chou, P. J., Perkins, I. & Klein, T. W. CB1 and CB2 cannabinoid receptors mediate different aspects of Δ9-tetrahydrocannabinol (THC)-induced T helper cell shift following immune activation by Legionella pneumophila infection. J. Neuroimmune Pharmacol. 4, 92-102 (2009).
-
(2009)
J. Neuroimmune Pharmacol.
, vol.4
, pp. 92-102
-
-
Newton, C.A.1
Chou, P.J.2
Perkins, I.3
Klein, T.W.4
-
66
-
-
33749014963
-
Cannabinoid treatment suppresses the T-helper cell-polarizing function of mouse dendritic cells stimulated with Legionella pneumophila infection
-
DOI 10.1124/jpet.106.108381
-
Lu, T., Newton, C., Perkins, I., Friedman, H. & Klein, T. W. Cannabinoid treatment suppresses the T-helper cell-polarizing function of mouse dendritic cells stimulated with Legionella pneumophila infection. J. Pharmacol. Exp. Ther. 319, 269-276 (2006). (Pubitemid 44455132)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.319
, Issue.1
, pp. 269-276
-
-
Lu, T.1
Newton, C.2
Perkins, I.3
Friedman, H.4
Klein, T.W.5
-
67
-
-
17144400758
-
Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice
-
DOI 10.1038/nature03389
-
Steffens, S. et al. Low dose oral cannabinoid therapy reduces progression of atherosclerosis in mice. Nature 434, 782-786 (2005). (Pubitemid 44739523)
-
(2005)
Nature
, vol.434
, Issue.7034
, pp. 782-786
-
-
Steffens, S.1
Veillard, N.R.2
Arnaud, C.3
Pelli, G.4
Burger, F.5
Staub, C.6
Zimmer, A.7
Frossard, J.-L.8
Mach, F.9
-
68
-
-
78649605467
-
Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties
-
Hegde, V. L., Nagarkatti, M. & Nagarkatti, P. S. Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties. Eur. J. Immunol. 40, 3358-3371 (2010).
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 3358-3371
-
-
Hegde, V.L.1
Nagarkatti, M.2
Nagarkatti, P.S.3
-
69
-
-
65549122582
-
Endocannabinoids, and related analogs in inflammation
-
Burstein, S. H. & Zurier, R. B. Cannabinoids, endocannabinoids, and related analogs in inflammation. AAPS J. 11, 109-119 (2009).
-
(2009)
AAPS J
, vol.11
, pp. 109-119
-
-
Burstein, S.H.1
Zurier, R.B.2
-
70
-
-
79952279722
-
Cannabis-derived substances in cancer therapy-an emerging anti-inflammatory role for the cannabinoids
-
Liu, W. M., Fowler, D. W. & Dalgleish, A. G. Cannabis-derived substances in cancer therapy-an emerging anti-inflammatory role for the cannabinoids. Curr. Clin. Pharmacol. 5, 281-287 (2010).
-
(2010)
Curr. Clin. Pharmacol
, vol.5
, pp. 281-287
-
-
Liu, W.M.1
Fowler, D.W.2
Dalgleish, A.G.3
-
71
-
-
73549098434
-
Ligand-and heterodimer-directed signaling of the CB1 cannabinoid receptor
-
Hudson, B. D., Hebert, T. E. & Kelly, M. E. Ligand-and heterodimer-directed signaling of the CB1 cannabinoid receptor. Mol. Pharmacol. 77, 1-9 (2010).
-
(2010)
Mol. Pharmacol.
, vol.77
, pp. 1-9
-
-
Hudson, B.D.1
Hebert, T.E.2
Kelly, M.E.3
-
72
-
-
77950632004
-
Interaction of endocannabinoid receptors with biological membranes
-
Dainese, E., Oddi, S. & Maccarrone, M. Interaction of endocannabinoid receptors with biological membranes. Curr. Med. Chem. 17, 1487-1499 (2010).
-
(2010)
Curr. Med. Chem.
, vol.17
, pp. 1487-1499
-
-
Dainese, E.1
Oddi, S.2
MacCarrone, M.3
-
73
-
-
77952643387
-
Cannabinoid CB1 receptor-interacting proteins: Novel targets for central nervous system drug discovery?
-
Smith, T. H., Sim-Selley, L. J. & Selley, D. E. Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery? Br. J. Pharmacol. 160, 454-466 (2010).
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 454-466
-
-
Smith, T.H.1
Sim-Selley, L.J.2
Selley, D.E.3
-
74
-
-
23744517089
-
Identification of midkine as a mediator for intercellular transfer of drug resistance
-
DOI 10.1038/sj.onc.1208671
-
Mirkin, B. L. et al. Identification of midkine as a mediator for intercellular transfer of drug resistance. Oncogene 24, 4965-4974 (2005). (Pubitemid 41129100)
-
(2005)
Oncogene
, vol.24
, Issue.31
, pp. 4965-4974
-
-
Mirkin, B.L.1
Clark, S.2
Zheng, X.3
Chu, F.4
White, B.D.5
Greene, M.6
Rebbaa, A.7
-
75
-
-
34250204188
-
The midkine family in cancer, inflammation and neural development
-
Kadomatsu, K. The midkine family in cancer, inflammation and neural development. Nagoya J. Med. Sci. 67, 71-82 (2005).
-
(2005)
Nagoya J. Med. Sci.
, vol.67
, pp. 71-82
-
-
Kadomatsu, K.1
-
76
-
-
66949152073
-
Anaplastic lymphoma kinase: Signalling in development and disease
-
Palmer, R. H., Vernersson, E., Grabbe, C. & Hallberg, B. Anaplastic lymphoma kinase: signalling in development and disease. Biochem. J. 420, 345-361 (2009).
-
(2009)
Biochem. J.
, vol.420
, pp. 345-361
-
-
Palmer, R.H.1
Vernersson, E.2
Grabbe, C.3
Hallberg, B.4
-
77
-
-
77957364747
-
Translating cancer research into targeted therapeutics
-
de Bono, J. S. & Ashworth, A. Translating cancer research into targeted therapeutics. Nature 467, 543-549 (2010).
-
(2010)
Nature
, vol.467
, pp. 543-549
-
-
De Bono, J.S.1
Ashworth, A.2
-
78
-
-
79955755025
-
Targeting oncogenic ALK: A promising strategy for cancer treatment
-
Grande, E., Bolos, M. V. & Arriola, E. Targeting oncogenic ALK: a promising strategy for cancer treatment. Mol. Cancer Ther. 10, 569-579 (2011).
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 569-579
-
-
Grande, E.1
Bolos, M.V.2
Arriola, E.3
-
79
-
-
70349088987
-
Amphiregulin is a factor for resistance of glioma cells to cannabinoid-induced apoptosis
-
Lorente, M. et al. Amphiregulin is a factor for resistance of glioma cells to cannabinoid-induced apoptosis. Glia 57, 1374-1385 (2009).
-
(2009)
Glia
, vol.57
, pp. 1374-1385
-
-
Lorente, M.1
-
80
-
-
78751527443
-
A combined preclinical therapy of cannabinoids and temozolomide against glioma
-
Torres, S. et al. A combined preclinical therapy of cannabinoids and temozolomide against glioma. Mol. Cancer Ther. 10, 90-103 (2011).
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 90-103
-
-
Torres, S.1
-
81
-
-
79959956124
-
Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism
-
Donadelli, M. et al. Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism. Cell Death Dis. 2, e152 (2011).
-
(2011)
Cell Death Dis.
, vol.2
-
-
Donadelli, M.1
-
82
-
-
67349195495
-
Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines
-
Miyato, H. et al. Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. J. Surg. Res. 155, 40-47 (2009).
-
(2009)
J. Surg. Res.
, vol.155
, pp. 40-47
-
-
Miyato, H.1
-
83
-
-
58849113520
-
Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: Synergism with 5-fluorouracil
-
Gustafsson, S. B., Lindgren, T., Jonsson, M. & Jacobsson, S. O. Cannabinoid receptor-independent cytotoxic effects of cannabinoids in human colorectal carcinoma cells: synergism with 5-fluorouracil. Cancer Chemother. Pharmacol. 63, 691-701 (2009).
-
(2009)
Cancer Chemother. Pharmacol.
, vol.63
, pp. 691-701
-
-
Gustafsson, S.B.1
Lindgren, T.2
Jonsson, M.3
Jacobsson, S.O.4
-
84
-
-
73949139182
-
Cannabidiol enhances the inhibitory effects of Δ9- tetrahydrocannabinol on human glioblastoma cell proliferation and survival
-
Marcu, J. P. et al. Cannabidiol enhances the inhibitory effects of Δ9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival. Mol. Cancer Ther. 9, 180-189 (2010).
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 180-189
-
-
Marcu, J.P.1
-
85
-
-
0035651034
-
Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth
-
Bifulco, M. et al. Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth. FASEB J. 15, 2745-2747 (2001).
-
(2001)
FASEB J
, vol.15
, pp. 2745-2747
-
-
Bifulco, M.1
-
86
-
-
33744913027
-
2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway
-
DOI 10.1016/j.yexcr.2006.03.009, PII S0014482706001066
-
Herrera, B. et al. The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway. Exp. Cell Res. 312, 2121-2131 (2006). (Pubitemid 43850936)
-
(2006)
Experimental Cell Research
, vol.312
, Issue.11
, pp. 2121-2131
-
-
Herrera, B.1
Carracedo, A.2
Diez-Zaera, M.3
Gomez Del Pulgar, T.4
Guzman, M.5
Velasco, G.6
-
87
-
-
0038242819
-
TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
-
DOI 10.1126/science.1079817
-
Du, K., Herzig, S., Kulkarni, R. N. & Montminy, M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300, 1574-1577 (2003). (Pubitemid 36682889)
-
(2003)
Science
, vol.300
, Issue.5625
, pp. 1574-1577
-
-
Du, K.1
Herzig, S.2
Kulkarni, R.N.3
Montminy, M.4
-
88
-
-
4644226099
-
Cannabinoids down-regulate PI3K/Akt and Erk signalling pathways and activate proapoptotic function of Bad protein
-
DOI 10.1016/j.cellsig.2004.05.011, PII S0898656804001007
-
Ellert-Miklaszewska, A., Kaminska, B. & Konarska, L. Cannabinoids down-regulate PI3K/Akt and Erk signalling pathways and activate proapoptotic function of Bad protein. Cell Signal. 17, 25-37 (2005). (Pubitemid 39286777)
-
(2005)
Cellular Signalling
, vol.17
, Issue.1
, pp. 25-37
-
-
Ellert-Miklaszewska, A.1
Kaminska, B.2
Konarska, L.3
-
89
-
-
50649112355
-
JunD is involved in the antiproliferative effect of Δ9- tetrahydrocannabinol on human breast cancer cells
-
Caffarel, M. M. et al. JunD is involved in the antiproliferative effect of Δ9-tetrahydrocannabinol on human breast cancer cells. Oncogene 27, 5033-5044 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 5033-5044
-
-
Caffarel, M.M.1
-
90
-
-
17444402489
-
Adjuvant chemotherapy in the treatment of high grade gliomas
-
DOI 10.1016/j.ctrv.2004.12.005, PII S0305737204001914
-
Lonardi, S., Tosoni, A. & Brandes, A. A. Adjuvant chemotherapy in the treatment of high grade gliomas. Cancer Treat. Rev. 31, 79-89 (2005). (Pubitemid 40542887)
-
(2005)
Cancer Treatment Reviews
, vol.31
, Issue.2
, pp. 79-89
-
-
Lonardi, S.1
Tosoni, A.2
Brandes, A.A.3
-
91
-
-
33750719122
-
Therapeutic options for recurrent high-grade glioma in adult patients: Recent advances
-
DOI 10.1016/j.critrevonc.2006.06.007, PII S1040842806001156
-
Nieder, C., Adam, M., Molls, M. & Grosu, A. L. Therapeutic options for recurrent high-grade glioma in adult patients: recent advances. Crit. Rev. Oncol. Hematol. 60, 181-193 (2006). (Pubitemid 44709618)
-
(2006)
Critical Reviews in Oncology/Hematology
, vol.60
, Issue.3
, pp. 181-193
-
-
Nieder, C.1
Adam, M.2
Molls, M.3
Grosu, A.L.4
-
92
-
-
70350449411
-
Advances in the genetics of glioblastoma: Are we reaching critical mass?
-
Purow, B. & Schiff, D. Advances in the genetics of glioblastoma: are we reaching critical mass? Nature Rev. Neurol. 5, 419-426 (2009).
-
(2009)
Nature Rev. Neurol.
, vol.5
, pp. 419-426
-
-
Purow, B.1
Schiff, D.2
-
93
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
Stupp, R. et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352, 987-996 (2005). (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
94
-
-
77954789824
-
Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition
-
Caffarel, M. M. et al. Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition. Mol. Cancer 9, 196 (2010).
-
(2010)
Mol. Cancer
, vol.9
, pp. 196
-
-
Caffarel, M.M.1
-
95
-
-
67651183775
-
Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma
-
Oesch, S. et al. Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma. Mol. Cancer Ther. 8, 1838-1845 (2009).
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 1838-1845
-
-
Oesch, S.1
-
96
-
-
33751198532
-
Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma
-
Gustafsson, K., Christensson, B., Sander, B. & Flygare, J. Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma. Mol. Pharmacol. 70, 1612-1620 (2006).
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 1612-1620
-
-
Gustafsson, K.1
Christensson, B.2
Sander, B.3
Flygare, J.4
-
97
-
-
0037100312
-
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease
-
DOI 10.1182/blood-2002-01-0098
-
McKallip, R. J. et al. Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood 100, 627-634 (2002). (Pubitemid 34761128)
-
(2002)
Blood
, vol.100
, Issue.2
, pp. 627-634
-
-
McKallip, R.J.1
Lombard, C.2
Fisher, M.3
Martin, B.R.4
Ryu, S.5
Grant, S.6
Nagarkatti, P.S.7
Nagarkatti, M.8
-
98
-
-
33748417610
-
Δ9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of bad to mitochondria
-
DOI 10.1158/1541-7786.MCR-05-0193
-
Jia, W. et al. Δ9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria. Mol. Cancer Res. 4, 549-562 (2006). (Pubitemid 44341365)
-
(2006)
Molecular Cancer Research
, vol.4
, Issue.8
, pp. 549-562
-
-
Jia, W.1
Hegde, V.L.2
Singh, N.P.3
Sisco, D.4
Grant, S.5
Nagarkatti, M.6
Nagarkatti, P.S.7
-
99
-
-
0038751939
-
Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: Implication of epidermal growth factor receptor down-regulation and ceramide production
-
DOI 10.1002/pros.10190
-
Mimeault, M., Pommery, N., Wattez, N., Bailly, C. & Henichart, J. P. Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. Prostate 56, 1-12 (2003). (Pubitemid 36613150)
-
(2003)
Prostate
, vol.56
, Issue.1
, pp. 1-12
-
-
Mimeault, M.1
Pommery, N.2
Wattez, N.3
Bailly, C.4
Henichart, J.-P.5
-
100
-
-
70249094588
-
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB2
-
Olea-Herrero, N., Vara, D., Malagarie-Cazenave, S. & Diaz-Laviada, I. Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: involvement of CB2. Br. J. Cancer 101, 940-950 (2009).
-
(2009)
Br. J. Cancer
, vol.101
, pp. 940-950
-
-
Olea-Herrero, N.1
Vara, D.2
Malagarie-Cazenave, S.3
Diaz-Laviada, I.4
|