메뉴 건너뛰기




Volumn 10, Issue , 2012, Pages

BMP2 and mechanical loading cooperatively regulate immediate early signalling events in the BMP pathway

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SMAD5 PROTEIN;

EID: 84861510353     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-10-37     Document Type: Article
Times cited : (99)

References (69)
  • 1
    • 85045483986 scopus 로고    scopus 로고
    • Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review
    • iii-iv
    • Garrison KR, Donell S, Ryder J, Shemilt I, Mugford M, Harvey I, Song F. Clinical effectiveness and cost-effectiveness of bone morphogenetic proteins in the non-healing of fractures and spinal fusion: a systematic review. Health Technol Assess 2007, 11:1-150. iii-iv.
    • (2007) Health Technol Assess , vol.11 , pp. 1-150
    • Garrison, K.R.1    Donell, S.2    Ryder, J.3    Shemilt, I.4    Mugford, M.5    Harvey, I.6    Song, F.7
  • 2
    • 77956023094 scopus 로고    scopus 로고
    • The role of endogenous bone morphogenetic proteins in normal skeletal repair
    • Marsell R, Einhorn TA. The role of endogenous bone morphogenetic proteins in normal skeletal repair. Injury 2009, 40(Suppl 3):S4-7.
    • (2009) Injury , vol.40 , Issue.SUPPL. 3
    • Marsell, R.1    Einhorn, T.A.2
  • 3
    • 33751506452 scopus 로고    scopus 로고
    • BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
    • 10.1038/ng1916, 17099713
    • Tsuji K, Bandyopadhyay A, Harfe BD, Cox K, Kakar S, Gerstenfeld L, Einhorn T, Tabin CJ, Rosen V. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet 2006, 38:1424-1429. 10.1038/ng1916, 17099713.
    • (2006) Nat Genet , vol.38 , pp. 1424-1429
    • Tsuji, K.1    Bandyopadhyay, A.2    Harfe, B.D.3    Cox, K.4    Kakar, S.5    Gerstenfeld, L.6    Einhorn, T.7    Tabin, C.J.8    Rosen, V.9
  • 4
    • 70649108638 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in orthopaedic surgery
    • 10.1016/j.cytogfr.2009.10.003, 19892584
    • Axelrad TW, Einhorn TA. Bone morphogenetic proteins in orthopaedic surgery. Cytokine Growth Factor Rev 2009, 20:481-488. 10.1016/j.cytogfr.2009.10.003, 19892584.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 481-488
    • Axelrad, T.W.1    Einhorn, T.A.2
  • 5
    • 34447343823 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in clinical applications
    • 10.1111/j.1445-2197.2007.04175.x, 17635273
    • Gautschi OP, Frey SP, Zellweger R. Bone morphogenetic proteins in clinical applications. ANZ J Surg 2007, 77:626-631. 10.1111/j.1445-2197.2007.04175.x, 17635273.
    • (2007) ANZ J Surg , vol.77 , pp. 626-631
    • Gautschi, O.P.1    Frey, S.P.2    Zellweger, R.3
  • 6
    • 70649083092 scopus 로고    scopus 로고
    • Recent advances in BMP receptor signaling
    • 10.1016/j.cytogfr.2009.10.007, 19897402
    • Sieber C, Kopf J, Hiepen C, Knaus P. Recent advances in BMP receptor signaling. Cytokine Growth Factor Rev 2009, 20:343-355. 10.1016/j.cytogfr.2009.10.007, 19897402.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 343-355
    • Sieber, C.1    Kopf, J.2    Hiepen, C.3    Knaus, P.4
  • 7
    • 43949090746 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in tissue engineering: the road from the laboratory to the clinic, part I (basic concepts)
    • 10.1002/term.63, 18293427
    • Bessa PC, Casal M, Reis RL. Bone morphogenetic proteins in tissue engineering: the road from the laboratory to the clinic, part I (basic concepts). J Tissue Eng Regen Med 2008, 2:1-13. 10.1002/term.63, 18293427.
    • (2008) J Tissue Eng Regen Med , vol.2 , pp. 1-13
    • Bessa, P.C.1    Casal, M.2    Reis, R.L.3
  • 8
    • 77957255073 scopus 로고    scopus 로고
    • Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells
    • 10.1016/j.biocel.2010.07.018, 20691279
    • Boergermann JH, Kopf J, Yu PB, Knaus P. Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells. Int J Biochem Cell Biol 2010, 42:1802-1807. 10.1016/j.biocel.2010.07.018, 20691279.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1802-1807
    • Boergermann, J.H.1    Kopf, J.2    Yu, P.B.3    Knaus, P.4
  • 9
    • 36248995245 scopus 로고    scopus 로고
    • Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
    • 10.1016/j.cell.2007.09.027, 2200633, 18045539
    • Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM, De Robertis EM. Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 2007, 131:980-993. 10.1016/j.cell.2007.09.027, 2200633, 18045539.
    • (2007) Cell , vol.131 , pp. 980-993
    • Fuentealba, L.C.1    Eivers, E.2    Ikeda, A.3    Hurtado, C.4    Kuroda, H.5    Pera, E.M.6    De Robertis, E.M.7
  • 10
    • 72149125600 scopus 로고    scopus 로고
    • Boning up on Wolff's Law: mechanical regulation of the cells that make and maintain bone
    • 10.1016/j.jbiomech.2009.09.016, 19818443
    • Chen JH, Liu C, You L, Simmons CA. Boning up on Wolff's Law: mechanical regulation of the cells that make and maintain bone. J Biomech 2010, 43:108-118. 10.1016/j.jbiomech.2009.09.016, 19818443.
    • (2010) J Biomech , vol.43 , pp. 108-118
    • Chen, J.H.1    Liu, C.2    You, L.3    Simmons, C.A.4
  • 12
    • 45349087675 scopus 로고    scopus 로고
    • A brief review of bone adaptation to unloading
    • 10.1016/S1672-0229(08)60016-9, 18558381
    • Zhang P, Hamamura K, Yokota H. A brief review of bone adaptation to unloading. Genomics Proteomics Bioinformatics 2008, 6:4-7. 10.1016/S1672-0229(08)60016-9, 18558381.
    • (2008) Genomics Proteomics Bioinformatics , vol.6 , pp. 4-7
    • Zhang, P.1    Hamamura, K.2    Yokota, H.3
  • 13
    • 40849111286 scopus 로고    scopus 로고
    • Influence of age and mechanical stability on bone defect healing: age reverses mechanical effects
    • 10.1016/j.bone.2007.12.223, 18280233
    • Strube P, Sentuerk U, Riha T, Kaspar K, Mueller M, Kasper G, Matziolis G, Duda GN, Perka C. Influence of age and mechanical stability on bone defect healing: age reverses mechanical effects. Bone 2008, 42:758-764. 10.1016/j.bone.2007.12.223, 18280233.
    • (2008) Bone , vol.42 , pp. 758-764
    • Strube, P.1    Sentuerk, U.2    Riha, T.3    Kaspar, K.4    Mueller, M.5    Kasper, G.6    Matziolis, G.7    Duda, G.N.8    Perka, C.9
  • 15
    • 79960637431 scopus 로고    scopus 로고
    • Dynamic molecular processes mediate cellular mechanotransduction
    • 10.1038/nature10316, 21776077
    • Hoffman BD, Grashoff C, Schwartz MA. Dynamic molecular processes mediate cellular mechanotransduction. Nature 2011, 475:316-323. 10.1038/nature10316, 21776077.
    • (2011) Nature , vol.475 , pp. 316-323
    • Hoffman, B.D.1    Grashoff, C.2    Schwartz, M.A.3
  • 17
    • 77957851833 scopus 로고    scopus 로고
    • Mechanotransduction in bone repair and regeneration
    • 10.1096/fj.10-157370, 20505115
    • Huang C, Ogawa R. Mechanotransduction in bone repair and regeneration. Faseb J 2010, 24:3625-3632. 10.1096/fj.10-157370, 20505115.
    • (2010) Faseb J , vol.24 , pp. 3625-3632
    • Huang, C.1    Ogawa, R.2
  • 18
    • 80053386595 scopus 로고    scopus 로고
    • More than a feeling: discovering, understanding, and influencing mechanosensing pathways
    • 10.1016/j.copbio.2011.04.007, 21536426
    • Holle AW, Engler AJ. More than a feeling: discovering, understanding, and influencing mechanosensing pathways. Curr Opin Biotechnol 2011, 22:648-654. 10.1016/j.copbio.2011.04.007, 21536426.
    • (2011) Curr Opin Biotechnol , vol.22 , pp. 648-654
    • Holle, A.W.1    Engler, A.J.2
  • 19
    • 67649920749 scopus 로고    scopus 로고
    • Growth factors, matrices, and forces combine and control stem cells
    • 10.1126/science.1171643, 2847855, 19556500
    • Discher DE, Mooney DJ, Zandstra PW. Growth factors, matrices, and forces combine and control stem cells. Science 2009, 324:1673-1677. 10.1126/science.1171643, 2847855, 19556500.
    • (2009) Science , vol.324 , pp. 1673-1677
    • Discher, D.E.1    Mooney, D.J.2    Zandstra, P.W.3
  • 20
    • 27644583784 scopus 로고    scopus 로고
    • Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads
    • 10.1128/MCB.25.22.9845-9858.2005, 1280270, 16260601
    • Schmierer B, Hill CS. Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads. Mol Cell Biol 2005, 25:9845-9858. 10.1128/MCB.25.22.9845-9858.2005, 1280270, 16260601.
    • (2005) Mol Cell Biol , vol.25 , pp. 9845-9858
    • Schmierer, B.1    Hill, C.S.2
  • 21
    • 0042347689 scopus 로고    scopus 로고
    • Id proteins in development, cell cycle and cancer
    • 10.1016/S0962-8924(03)00147-8, 12888293
    • Ruzinova MB, Benezra R. Id proteins in development, cell cycle and cancer. Trends Cell Biol 2003, 13:410-418. 10.1016/S0962-8924(03)00147-8, 12888293.
    • (2003) Trends Cell Biol , vol.13 , pp. 410-418
    • Ruzinova, M.B.1    Benezra, R.2
  • 22
    • 0037468456 scopus 로고    scopus 로고
    • Preliminary characterisation of mechanoresponsive regions of the c-fos promoter in bone cells
    • 10.1016/S0014-5793(03)00108-X, 12606042
    • Peake MA, El Haj AJ. Preliminary characterisation of mechanoresponsive regions of the c-fos promoter in bone cells. FEBS Lett 2003, 537:117-120. 10.1016/S0014-5793(03)00108-X, 12606042.
    • (2003) FEBS Lett , vol.537 , pp. 117-120
    • Peake, M.A.1    El Haj, A.J.2
  • 24
    • 67649379048 scopus 로고    scopus 로고
    • Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction
    • 10.1074/jbc.M806486200, 2685661, 19282289
    • Rangaswami H, Marathe N, Zhuang S, Chen Y, Yeh JC, Frangos JA, Boss GR, Pilz RB. Type II cGMP-dependent protein kinase mediates osteoblast mechanotransduction. J Biol Chem 2009, 284:14796-14808. 10.1074/jbc.M806486200, 2685661, 19282289.
    • (2009) J Biol Chem , vol.284 , pp. 14796-14808
    • Rangaswami, H.1    Marathe, N.2    Zhuang, S.3    Chen, Y.4    Yeh, J.C.5    Frangos, J.A.6    Boss, G.R.7    Pilz, R.B.8
  • 25
    • 77951243657 scopus 로고    scopus 로고
    • Identification of a key residue mediating bone morphogenetic protein (BMP)-6 resistance to noggin inhibition allows for engineered BMPs with superior agonist activity
    • 10.1074/jbc.M109.087197, 2852956, 20048150
    • Song K, Krause C, Shi S, Patterson M, Suto R, Grgurevic L, Vukicevic S, van Dinther M, Falb D, Ten Dijke P, Alaoui-Ismaili MH. Identification of a key residue mediating bone morphogenetic protein (BMP)-6 resistance to noggin inhibition allows for engineered BMPs with superior agonist activity. J Biol Chem 2010, 285:12169-12180. 10.1074/jbc.M109.087197, 2852956, 20048150.
    • (2010) J Biol Chem , vol.285 , pp. 12169-12180
    • Song, K.1    Krause, C.2    Shi, S.3    Patterson, M.4    Suto, R.5    Grgurevic, L.6    Vukicevic, S.7    van Dinther, M.8    Falb, D.9    Ten Dijke, P.10    Alaoui-Ismaili, M.H.11
  • 26
    • 70649098149 scopus 로고    scopus 로고
    • Intricacies of BMP receptor assembly
    • 10.1016/j.cytogfr.2009.10.022, 19926516
    • Nickel J, Sebald W, Groppe JC, Mueller TD. Intricacies of BMP receptor assembly. Cytokine Growth Factor Rev 2009, 20:367-377. 10.1016/j.cytogfr.2009.10.022, 19926516.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 367-377
    • Nickel, J.1    Sebald, W.2    Groppe, J.C.3    Mueller, T.D.4
  • 27
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • 10.1016/j.cell.2006.06.044, 16923388
    • Engler AJ, Sen S, Sweeney HL, Discher DE. Matrix elasticity directs stem cell lineage specification. Cell 2006, 126:677-689. 10.1016/j.cell.2006.06.044, 16923388.
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 28
    • 77951228475 scopus 로고    scopus 로고
    • Mechanical control of tissue and organ development
    • 10.1242/dev.024166, 2853843, 20388652
    • Mammoto T, Ingber DE. Mechanical control of tissue and organ development. Development 2010, 137:1407-1420. 10.1242/dev.024166, 2853843, 20388652.
    • (2010) Development , vol.137 , pp. 1407-1420
    • Mammoto, T.1    Ingber, D.E.2
  • 29
  • 30
    • 79955422723 scopus 로고    scopus 로고
    • Biomechanical forces exert anabolic effects on osteoblasts by activation of SMAD 1/5/8 through type 1 BMP receptor
    • Rath B, Nam J, Deschner J, Schaumburger J, Tingart M, Grassel S, Grifka J, Agarwal S. Biomechanical forces exert anabolic effects on osteoblasts by activation of SMAD 1/5/8 through type 1 BMP receptor. Biorheology 2011, 48:37-48.
    • (2011) Biorheology , vol.48 , pp. 37-48
    • Rath, B.1    Nam, J.2    Deschner, J.3    Schaumburger, J.4    Tingart, M.5    Grassel, S.6    Grifka, J.7    Agarwal, S.8
  • 31
    • 77958564873 scopus 로고    scopus 로고
    • Mechanical stress activates Smad pathway through PKCdelta to enhance interleukin-11 gene transcription in osteoblasts
    • 10.1371/journal.pone.0013090, 2947522, 20927330
    • Kido S, Kuriwaka-Kido R, Umino-Miyatani Y, Endo I, Inoue D, Taniguchi H, Inoue Y, Imamura T, Matsumoto T. Mechanical stress activates Smad pathway through PKCdelta to enhance interleukin-11 gene transcription in osteoblasts. PLoS One 2010, 5:e13090. 10.1371/journal.pone.0013090, 2947522, 20927330.
    • (2010) PLoS One , vol.5
    • Kido, S.1    Kuriwaka-Kido, R.2    Umino-Miyatani, Y.3    Endo, I.4    Inoue, D.5    Taniguchi, H.6    Inoue, Y.7    Imamura, T.8    Matsumoto, T.9
  • 32
    • 78651231027 scopus 로고    scopus 로고
    • Involvement of BMPs/Smad signaling pathway in mechanical response in osteoblasts
    • 10.1159/000323987, 21220940
    • Wang L, Zhang X, Guo Y, Chen X, Li R, Liu L, Shi C, Guo C, Zhang Y. Involvement of BMPs/Smad signaling pathway in mechanical response in osteoblasts. Cell Physiol Biochem 2010, 26:1093-1102. 10.1159/000323987, 21220940.
    • (2010) Cell Physiol Biochem , vol.26 , pp. 1093-1102
    • Wang, L.1    Zhang, X.2    Guo, Y.3    Chen, X.4    Li, R.5    Liu, L.6    Shi, C.7    Guo, C.8    Zhang, Y.9
  • 33
    • 75949103899 scopus 로고    scopus 로고
    • Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing
    • 10.1038/embor.2009.276, 2828749, 20075988
    • Margadant C, Sonnenberg A. Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing. EMBO Rep 2010, 11:97-105. 10.1038/embor.2009.276, 2828749, 20075988.
    • (2010) EMBO Rep , vol.11 , pp. 97-105
    • Margadant, C.1    Sonnenberg, A.2
  • 34
    • 12544254440 scopus 로고    scopus 로고
    • Alphavbeta integrins play an essential role in BMP-2 induction of osteoblast differentiation
    • Lai CF, Cheng SL. Alphavbeta integrins play an essential role in BMP-2 induction of osteoblast differentiation. J Bone Miner Res 2005, 20:330-340.
    • (2005) J Bone Miner Res , vol.20 , pp. 330-340
    • Lai, C.F.1    Cheng, S.L.2
  • 35
    • 33750321665 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 promotes the haptotactic migration of murine osteoblastic and osteosarcoma cells by enhancing incorporation of integrin beta1 into lipid rafts
    • 10.1016/j.yexcr.2006.08.024, 17022972
    • Sotobori T, Ueda T, Myoui A, Yoshioka K, Nakasaki M, Yoshikawa H, Itoh K. Bone morphogenetic protein-2 promotes the haptotactic migration of murine osteoblastic and osteosarcoma cells by enhancing incorporation of integrin beta1 into lipid rafts. Exp Cell Res 2006, 312:3927-3938. 10.1016/j.yexcr.2006.08.024, 17022972.
    • (2006) Exp Cell Res , vol.312 , pp. 3927-3938
    • Sotobori, T.1    Ueda, T.2    Myoui, A.3    Yoshioka, K.4    Nakasaki, M.5    Yoshikawa, H.6    Itoh, K.7
  • 36
    • 77956191832 scopus 로고    scopus 로고
    • Differentiation of pre-osteoblast cells on poly(ethylene terephthalate) grafted with RGD and/or BMPs mimetic peptides
    • 10.1016/j.biomaterials.2010.07.042, 20667411
    • Zouani OF, Chollet C, Guillotin B, Durrieu MC. Differentiation of pre-osteoblast cells on poly(ethylene terephthalate) grafted with RGD and/or BMPs mimetic peptides. Biomaterials 2010, 31:8245-8253. 10.1016/j.biomaterials.2010.07.042, 20667411.
    • (2010) Biomaterials , vol.31 , pp. 8245-8253
    • Zouani, O.F.1    Chollet, C.2    Guillotin, B.3    Durrieu, M.C.4
  • 37
    • 27644572195 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension
    • 10.1165/rcmb.2005-0103OC, 2715351, 16002577
    • Wong WK, Knowles JA, Morse JH. Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension. Am J Respir Cell Mol Biol 2005, 33:438-446. 10.1165/rcmb.2005-0103OC, 2715351, 16002577.
    • (2005) Am J Respir Cell Mol Biol , vol.33 , pp. 438-446
    • Wong, W.K.1    Knowles, J.A.2    Morse, J.H.3
  • 38
    • 34250370351 scopus 로고    scopus 로고
    • Receptor for activated C-kinase 1, a novel interaction partner of type II bone morphogenetic protein receptor, regulates smooth muscle cell proliferation in pulmonary arterial hypertension
    • 10.1161/CIRCULATIONAHA.106.670026, 17515463
    • Zakrzewicz A, Hecker M, Marsh LM, Kwapiszewska G, Nejman B, Long L, Seeger W, Schermuly RT, Morrell NW, Morty RE, Eickelberg O. Receptor for activated C-kinase 1, a novel interaction partner of type II bone morphogenetic protein receptor, regulates smooth muscle cell proliferation in pulmonary arterial hypertension. Circulation 2007, 115:2957-2968. 10.1161/CIRCULATIONAHA.106.670026, 17515463.
    • (2007) Circulation , vol.115 , pp. 2957-2968
    • Zakrzewicz, A.1    Hecker, M.2    Marsh, L.M.3    Kwapiszewska, G.4    Nejman, B.5    Long, L.6    Seeger, W.7    Schermuly, R.T.8    Morrell, N.W.9    Morty, R.E.10    Eickelberg, O.11
  • 39
    • 79959345857 scopus 로고    scopus 로고
    • Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity
    • 10.1073/pnas.1106467108, 3111285, 21593411
    • Du J, Chen X, Liang X, Zhang G, Xu J, He L, Zhan Q, Feng XQ, Chien S, Yang C. Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity. Proc Natl Acad Sci USA 2011, 108:9466-9471. 10.1073/pnas.1106467108, 3111285, 21593411.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 9466-9471
    • Du, J.1    Chen, X.2    Liang, X.3    Zhang, G.4    Xu, J.5    He, L.6    Zhan, Q.7    Feng, X.Q.8    Chien, S.9    Yang, C.10
  • 40
    • 33749586993 scopus 로고    scopus 로고
    • Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signaling
    • 10.1128/MCB.00022-06, 1636853, 16923969
    • Hartung A, Bitton-Worms K, Rechtman MM, Wenzel V, Boergermann JH, Hassel S, Henis YI, Knaus P. Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signaling. Mol Cell Biol 2006, 26:7791-7805. 10.1128/MCB.00022-06, 1636853, 16923969.
    • (2006) Mol Cell Biol , vol.26 , pp. 7791-7805
    • Hartung, A.1    Bitton-Worms, K.2    Rechtman, M.M.3    Wenzel, V.4    Boergermann, J.H.5    Hassel, S.6    Henis, Y.I.7    Knaus, P.8
  • 41
    • 80053595685 scopus 로고    scopus 로고
    • Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells
    • 10.1371/journal.pone.0025163, 3187766, 21998639
    • Heining E, Bhushan R, Paarmann P, Henis YI, Knaus P. Spatial segregation of BMP/Smad signaling affects osteoblast differentiation in C2C12 cells. PLoS One 2011, 6:e25163. 10.1371/journal.pone.0025163, 3187766, 21998639.
    • (2011) PLoS One , vol.6
    • Heining, E.1    Bhushan, R.2    Paarmann, P.3    Henis, Y.I.4    Knaus, P.5
  • 43
    • 66149127591 scopus 로고    scopus 로고
    • Hydrostatic pressures promote initial osteodifferentiation with ERK1/2 not p38 MAPK signaling involved
    • 10.1002/jcb.22118, 19259952
    • Liu J, Zhao Z, Li J, Zou L, Shuler C, Zou Y, Huang X, Li M, Wang J. Hydrostatic pressures promote initial osteodifferentiation with ERK1/2 not p38 MAPK signaling involved. J Cell Biochem 2009, 107:224-232. 10.1002/jcb.22118, 19259952.
    • (2009) J Cell Biochem , vol.107 , pp. 224-232
    • Liu, J.1    Zhao, Z.2    Li, J.3    Zou, L.4    Shuler, C.5    Zou, Y.6    Huang, X.7    Li, M.8    Wang, J.9
  • 44
    • 33744954151 scopus 로고    scopus 로고
    • A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation
    • 10.1074/jbc.M510680200, 16464862
    • Lewthwaite JC, Bastow ER, Lamb KJ, Blenis J, Wheeler-Jones CP, Pitsillides AA. A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation. J Biol Chem 2006, 281:11011-11018. 10.1074/jbc.M510680200, 16464862.
    • (2006) J Biol Chem , vol.281 , pp. 11011-11018
    • Lewthwaite, J.C.1    Bastow, E.R.2    Lamb, K.J.3    Blenis, J.4    Wheeler-Jones, C.P.5    Pitsillides, A.A.6
  • 47
    • 66149100833 scopus 로고    scopus 로고
    • Global transcriptome analysis in mouse calvarial osteoblasts highlights sets of genes regulated by modeled microgravity and identifies a "mechanoresponsive osteoblast gene signature"
    • 10.1002/jcb.22120, 19288527
    • Capulli M, Rufo A, Teti A, Rucci N. Global transcriptome analysis in mouse calvarial osteoblasts highlights sets of genes regulated by modeled microgravity and identifies a "mechanoresponsive osteoblast gene signature". J Cell Biochem 2009, 107:240-252. 10.1002/jcb.22120, 19288527.
    • (2009) J Cell Biochem , vol.107 , pp. 240-252
    • Capulli, M.1    Rufo, A.2    Teti, A.3    Rucci, N.4
  • 48
    • 40249109986 scopus 로고    scopus 로고
    • Compressive forces induce osteogenic gene expression in calvarial osteoblasts
    • 10.1016/j.jbiomech.2007.11.024, 2291547, 18191137
    • Rath B, Nam J, Knobloch TJ, Lannutti JJ, Agarwal S. Compressive forces induce osteogenic gene expression in calvarial osteoblasts. J Biomech 2008, 41:1095-1103. 10.1016/j.jbiomech.2007.11.024, 2291547, 18191137.
    • (2008) J Biomech , vol.41 , pp. 1095-1103
    • Rath, B.1    Nam, J.2    Knobloch, T.J.3    Lannutti, J.J.4    Agarwal, S.5
  • 49
    • 71849114315 scopus 로고    scopus 로고
    • Synergistic action of static stretching and BMP-2 stimulation in the osteoblast differentiation of C2C12 myoblasts
    • 10.1016/j.jbiomech.2009.08.006, 19766220
    • Kim IS, Song YM, Cho TH, Kim JY, Weber FE, Hwang SJ. Synergistic action of static stretching and BMP-2 stimulation in the osteoblast differentiation of C2C12 myoblasts. J Biomech 2009, 42:2721-2727. 10.1016/j.jbiomech.2009.08.006, 19766220.
    • (2009) J Biomech , vol.42 , pp. 2721-2727
    • Kim, I.S.1    Song, Y.M.2    Cho, T.H.3    Kim, J.Y.4    Weber, F.E.5    Hwang, S.J.6
  • 50
    • 0033515523 scopus 로고    scopus 로고
    • Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells
    • Morawietz H, Ma YH, Vives F, Wilson E, Sukhatme VP, Holtz J, Ives HE. Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells. Circ Res 1999, 84:678-687.
    • (1999) Circ Res , vol.84 , pp. 678-687
    • Morawietz, H.1    Ma, Y.H.2    Vives, F.3    Wilson, E.4    Sukhatme, V.P.5    Holtz, J.6    Ives, H.E.7
  • 51
    • 0037013229 scopus 로고    scopus 로고
    • Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells
    • 10.1074/jbc.M200794200, 11854297
    • Lai CF, Cheng SL. Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells. J Biol Chem 2002, 277:15514-15522. 10.1074/jbc.M200794200, 11854297.
    • (2002) J Biol Chem , vol.277 , pp. 15514-15522
    • Lai, C.F.1    Cheng, S.L.2
  • 52
    • 0033674978 scopus 로고    scopus 로고
    • Reduced expression of BMP-3 due to mechanical loading: a link between mechanical stimuli and tissue differentiation
    • 10.1080/000164700317362172, 11145381
    • Aspenberg P, Basic N, Tagil M, Vukicevic S. Reduced expression of BMP-3 due to mechanical loading: a link between mechanical stimuli and tissue differentiation. Acta Orthop Scand 2000, 71:558-562. 10.1080/000164700317362172, 11145381.
    • (2000) Acta Orthop Scand , vol.71 , pp. 558-562
    • Aspenberg, P.1    Basic, N.2    Tagil, M.3    Vukicevic, S.4
  • 53
    • 33646055172 scopus 로고    scopus 로고
    • Optimal compressive force induces bone formation via increasing bone morphogenetic proteins production and decreasing their antagonists production by Saos-2 cells
    • 10.1016/j.lfs.2005.10.024, 16337660
    • Mitsui N, Suzuki N, Maeno M, Yanagisawa M, Koyama Y, Otsuka K, Shimizu N. Optimal compressive force induces bone formation via increasing bone morphogenetic proteins production and decreasing their antagonists production by Saos-2 cells. Life Sci 2006, 78:2697-2706. 10.1016/j.lfs.2005.10.024, 16337660.
    • (2006) Life Sci , vol.78 , pp. 2697-2706
    • Mitsui, N.1    Suzuki, N.2    Maeno, M.3    Yanagisawa, M.4    Koyama, Y.5    Otsuka, K.6    Shimizu, N.7
  • 54
    • 33646902229 scopus 로고    scopus 로고
    • Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear
    • Lau KH, Kapur S, Kesavan C, Baylink DJ. Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear. J Biol Chem 2006, 281:9576-9588.
    • (2006) J Biol Chem , vol.281 , pp. 9576-9588
    • Lau, K.H.1    Kapur, S.2    Kesavan, C.3    Baylink, D.J.4
  • 55
    • 0032970328 scopus 로고    scopus 로고
    • Mechanical tension-stress induces expression of bone morphogenetic protein (BMP)-2 and BMP-4, but not BMP-6, BMP-7, and GDF-5 mRNA, during distraction osteogenesis
    • 10.1359/jbmr.1999.14.7.1084, 10404008
    • Sato M, Ochi T, Nakase T, Hirota S, Kitamura Y, Nomura S, Yasui N. Mechanical tension-stress induces expression of bone morphogenetic protein (BMP)-2 and BMP-4, but not BMP-6, BMP-7, and GDF-5 mRNA, during distraction osteogenesis. J Bone Miner Res 1999, 14:1084-1095. 10.1359/jbmr.1999.14.7.1084, 10404008.
    • (1999) J Bone Miner Res , vol.14 , pp. 1084-1095
    • Sato, M.1    Ochi, T.2    Nakase, T.3    Hirota, S.4    Kitamura, Y.5    Nomura, S.6    Yasui, N.7
  • 56
    • 39149143035 scopus 로고    scopus 로고
    • Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis
    • 10.1177/154405910808700215, 3109437, 18218835
    • Ai-Aql ZS, Alagl AS, Graves DT, Gerstenfeld LC, Einhorn TA. Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis. J Dent Res 2008, 87:107-118. 10.1177/154405910808700215, 3109437, 18218835.
    • (2008) J Dent Res , vol.87 , pp. 107-118
    • Ai-Aql, Z.S.1    Alagl, A.S.2    Graves, D.T.3    Gerstenfeld, L.C.4    Einhorn, T.A.5
  • 58
    • 45849126191 scopus 로고    scopus 로고
    • Mechanical load and BMP signaling during tendon repair: a role for follistatin?
    • 10.1007/s11999-008-0253-0, 2505240, 18421531
    • Eliasson P, Fahlgren A, Aspenberg P. Mechanical load and BMP signaling during tendon repair: a role for follistatin?. Clin Orthop Relat Res 2008, 466:1592-1597. 10.1007/s11999-008-0253-0, 2505240, 18421531.
    • (2008) Clin Orthop Relat Res , vol.466 , pp. 1592-1597
    • Eliasson, P.1    Fahlgren, A.2    Aspenberg, P.3
  • 59
    • 58049211966 scopus 로고    scopus 로고
    • Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus
    • Wang N, Tytell JD, Ingber DE. Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus. Nat Rev Mol Cell Biol 2009, 10:75-82.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 75-82
    • Wang, N.1    Tytell, J.D.2    Ingber, D.E.3
  • 60
    • 18144411595 scopus 로고    scopus 로고
    • The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines
    • 10.1074/jbc.M411234200, 15647271
    • Pan D, Estevez-Salmeron LD, Stroschein SL, Zhu X, He J, Zhou S, Luo K. The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines. J Biol Chem 2005, 280:15992-16001. 10.1074/jbc.M411234200, 15647271.
    • (2005) J Biol Chem , vol.280 , pp. 15992-16001
    • Pan, D.1    Estevez-Salmeron, L.D.2    Stroschein, S.L.3    Zhu, X.4    He, J.5    Zhou, S.6    Luo, K.7
  • 61
    • 76649104718 scopus 로고    scopus 로고
    • Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?
    • 10.1242/jcs.041186, 2816180, 20130138
    • Buxboim A, Ivanovska IL, Discher DE. Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?. J Cell Sci 2010, 123:297-308. 10.1242/jcs.041186, 2816180, 20130138.
    • (2010) J Cell Sci , vol.123 , pp. 297-308
    • Buxboim, A.1    Ivanovska, I.L.2    Discher, D.E.3
  • 64
    • 79954613301 scopus 로고    scopus 로고
    • Inter-species investigation of the mechano-regulation of bone healing: comparison of secondary bone healing in sheep and rat
    • 10.1016/j.jbiomech.2011.02.074, 21419412
    • Checa S, Prendergast PJ, Duda GN. Inter-species investigation of the mechano-regulation of bone healing: comparison of secondary bone healing in sheep and rat. J Biomech 2011, 44:1237-1245. 10.1016/j.jbiomech.2011.02.074, 21419412.
    • (2011) J Biomech , vol.44 , pp. 1237-1245
    • Checa, S.1    Prendergast, P.J.2    Duda, G.N.3
  • 66
    • 0034989649 scopus 로고    scopus 로고
    • Duration and frequency of every day activities in total hip patients
    • 10.1016/S0021-9290(01)00035-5, 11410171
    • Morlock M, Schneider E, Bluhm A, Vollmer M, Bergmann G, Muller V, Honl M. Duration and frequency of every day activities in total hip patients. J Biomech 2001, 34:873-881. 10.1016/S0021-9290(01)00035-5, 11410171.
    • (2001) J Biomech , vol.34 , pp. 873-881
    • Morlock, M.1    Schneider, E.2    Bluhm, A.3    Vollmer, M.4    Bergmann, G.5    Muller, V.6    Honl, M.7
  • 67
    • 0037085441 scopus 로고    scopus 로고
    • Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
    • 10.1074/jbc.M111023200, 11729207
    • Korchynskyi O, ten Dijke P. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J Biol Chem 2002, 277:4883-4891. 10.1074/jbc.M111023200, 11729207.
    • (2002) J Biol Chem , vol.277 , pp. 4883-4891
    • Korchynskyi, O.1    ten Dijke, P.2
  • 69
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • 126239, 12184808
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002, 3:RESEARCH0034. 126239, 12184808.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.