Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 10, 2008, Pages 3927-3932

  Chang, Shun Fu ^a,b   Chang, Cheng Allen ^a   Lee, Ding Yu ^b   Lee, Pei Ling ^b   Yeh, Yu Ming ^b   Yeh, Chiuan Ren ^c   Cheng, Kung ^c   Chien, Shu ^d   Chiu, Jeng Jiann ^b,c  

^a NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

BMP; Differentiation; Mechanical force; Runx2

Indexed keywords

ALKALINE PHOSPHATASE; ANTIBODY; BETA1 INTEGRIN; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; CYCLIN A; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; INTEGRIN; NOGGIN; OSTEOCALCIN; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX2; VITRONECTIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 1; CELL CYCLE PROTEIN; RUNX2 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL DIFFERENTIATION; CELL FUNCTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; METASTASIS; MICROENVIRONMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SHEAR STRESS; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR GROWTH; BIOLOGICAL MODEL; CELL CYCLE; CELL NUCLEUS; MECHANICAL STRESS; METABOLISM; MITOSIS; NEOPLASM; PATHOLOGY; PHOSPHORYLATION; PROTEIN BINDING;

ANTIGENS, CD29; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL NUCLEUS; CORE BINDING FACTOR ALPHA 1 SUBUNIT; G2 PHASE; HUMANS; INTEGRIN ALPHAVBETA3; INTEGRINS; MITOSIS; MODELS, BIOLOGICAL; NEOPLASMS; PHOSPHORYLATION; PROTEIN BINDING; SMAD PROTEINS; SMAD1 PROTEIN; SMAD5 PROTEIN; STRESS, MECHANICAL;

EID: 41649091020     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0712353105     Document Type: Article

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