Biomechanical forces exert anabolic effects on osteoblasts by activation of SMAD 1/5/8 through type 1 BMP receptor

Biorheology

Volumn 48, Issue 1, 2011, Pages 37-48

  Rath, B ^a,b   Deschner, J ^c   Schaumburger, J ^a   Tingart, M ^d   Grassel S ^a   Grifka, J ^a   Agarwal, S ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF BONN   (Germany)

^d UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

BMP; dorsomorphin; mechanical signals; Scaffold; SMAD signaling

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR 1; OSTEOPROTEGERIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; BIOMECHANICS; CELL CULTURE; GENE CONTROL; GENE EXPRESSION; HUMAN; METABOLISM; MONOLAYER CULTURE; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BIOMECHANICS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; MECHANICAL PROCESSES; OSTEOBLASTS; OSTEOGENESIS; PHOSPHORYLATION; PYRAZOLES; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SMAD PROTEINS, RECEPTOR-REGULATED; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; STRESS, MECHANICAL; TRANSCRIPTIONAL ACTIVATION;

EID: 79955422723     PISSN: 0006355X     EISSN: 18785034     Source Type: Journal    
DOI: 10.3233/BIR-2011-0580     Document Type: Article

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