Reduced expression of BMP-3 due to mechanical loading: A link between mechanical stimuli and tissue differentiation

Acta Orthopaedica Scandinavica

Volumn 71, Issue 6, 2000, Pages 558-562

  Aspenberg, P ^a   Basic, N ^a   Tagil, M ^a   Vukicevic, S ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CYTOKINE; OSTEOGENIN; TRANSFORMING GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARTILAGE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; MALE; MECHANICAL STRESS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIBIA; TISSUE DIFFERENTIATION;

EID: 0033674978     PISSN: 00016470     EISSN: None     Source Type: Journal    
DOI: 10.1080/000164700317362172     Document Type: Article

References (12)

1. Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing
2. Enhancement of bone formation in the setting of repeated tissue deformation
3. Mechanobiologic regulation of osteogenesis and arthrogenesis
4. Effects of mechanical factors on the fracture healing process
5. BMP-3 is a negative regulator of osteogenesis in vitro and in vivo
6. Intraosseous BMP implants in rabbits. Inhibitory effect on bone formation
7. Bone morphogenetic proteins in the formation and repair of cartilage bone and joints
8. Morphogenesis of digits in the avian limb is controlled by FGFs, TGFbetas, and noggin through BMP signaling
9. Eine neue theorie uber den einfluss mechanischer reize auf die differenzierung der stutzgewebe
10. Mechanical tension-stress induces expression of bone morphogenetic protein (BMP)-2 and BMP-4, but not BMP-6, BMP-7, and GDF-5 mRNA, during distraction osteogenesis
11. Cartilage induction by controlled mechanical stimulation in vivo
12. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4