Enantioselective β-arylation of ketones enabled by lithiation/borylation/1,4-addition sequence under flow conditions

Angewandte Chemie - International Edition

Volumn 51, Issue 22, 2012, Pages 5355-5358

  Shu, Wei ^a   Buchwald, Stephen L ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

arylation; 1,4 addition; asymmetric catalysis; flow chemistry; multistep reactions

Indexed keywords

1 ,4-ADDITION; ARYLATIONS; ASYMMETRIC CATALYSIS; FLOW CHEMISTRY; MULTISTEP REACTIONS;

CATALYSIS; ENANTIOSELECTIVITY; KETONES;

AROMATIC COMPOUNDS;

AROMATIC HYDROCARBON; BORON DERIVATIVE; KETONE; LITHIUM DERIVATIVE; RHODIUM;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

BORON COMPOUNDS; CATALYSIS; HYDROCARBONS, AROMATIC; KETONES; LITHIUM COMPOUNDS; MOLECULAR STRUCTURE; RHODIUM; STEREOISOMERISM;

EID: 84861488396     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201202221     Document Type: Article

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