5-(Pyrrolidin-2-yl)tetrazole-catalyzed aldol and mannich reactions: Acceleration and lower catalyst loading in a continuous-flow reactor

Angewandte Chemie - International Edition

Volumn 48, Issue 15, 2009, Pages 2699-2702

  Odedra, Arjan ^a   Seeberger, Peter H ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Aldol reaction; Asymmetric catalysis; Continuous flow reactors; Microreactors; Organocatalysis

Indexed keywords

ALDOL REACTION; ASYMMETRIC CATALYSIS; CONTINUOUS-FLOW REACTORS; MICROREACTORS; ORGANOCATALYSIS;

ALDEHYDES; CATALYSTS; CHEMICAL REACTORS; KETONES; RATE CONSTANTS; REACTION KINETICS; SUGAR (SUCROSE);

CATALYSIS;

5-(PYRROLIDIN-2-YL)TETRAZOLE; ALDEHYDE; KETONE; PROLINE; PYRROLIDINE DERIVATIVE; TETRAZOLE DERIVATIVE;

CATALYSIS; CHEMISTRY; STEREOISOMERISM; SYNTHESIS; TEMPERATURE; TIME;

ALDEHYDES; CATALYSIS; KETONES; PROLINE; PYRROLIDINES; STEREOISOMERISM; TEMPERATURE; TETRAZOLES; TIME FACTORS;

EID: 70349785019     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200804407     Document Type: Article

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