Ten key issues in modern flow chemistry

Chemical Communications

Volumn 47, Issue 16, 2011, Pages 4583-4592

  Wegner, Jens ^a   Ceylan, Sascha ^a   Kirschning, Andreas ^a  

^a LEIBNIZ UNIVERSITY HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOREACTOR; CATALYST; FLOW CHEMISTRY; FLOW KINETICS; FLOW RATE; HEAT TRANSFER; MICROFLUIDICS; ORGANIC CHEMISTRY; PARTICLE SIZE; PHOTOCHEMISTRY; PRESSURE; REVIEW; SYNTHESIS;

EID: 79953702549     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c0cc05060a     Document Type: Article

References (84)

1. C. O. Kappe, D. Dallinger, Mol. Diversity, 2009, 13, 71
2. S. Caddick, R. Fitzmaurice, Tetrahedron, 2009, 65, 3325
3. In Microwave-Assisted Organic Synthesis, ed. P. Lidström and J. P. Tierney, Blackwell Publishing, Oxford, UK, 2005
4. In Microwaves in Organic Synthesis, ed. A. Loupy, Wiley-VCH, Weinheim, Germany, 2nd edn, 2006
5. M. P. Dudukovic, F. Larachi, P. L. Mills, Chem. Eng. Sci., 1999, 54, 1975
6. G. M. Whiteside, Nature, 2006, 442, 368
7. V. Hessel, Chem. Eng. Technol., 2009, 32, 1655
8. K. Geyer, T. Gustafson, P. H. Seeberger, Synlett, 2009, 2382
9. R. L. Hartman, K. F. Jensen, Lab Chip, 2009, 9, 2495
10. X. Y. Mak, P. Laurino, P. H. Seeberger, Beilstein J. Org. Chem., 2009, 5, 19
11. C. Wiles, P. Watts, Eur. J. Org. Chem., 2008, 1655
12. T. Fukuyama, M. T. Rahman, M. Sato, I. Ryu, Synlett, 2008, 151
13. B. Ahmed-Omer, J. C. Brandt, T. Wirth, Org. Biomol. Chem., 2007, 5, 733
14. P. Watts, C. Wiles, Chem. Commun., 2007, 433
15. B. P. Mason, K. E. Price, J. L. Steinbacher, A. R. Bogdan, D. T. McQuade, Chem. Rev., 2007, 107, 2300
16. J. Kobayashi, Y. Mori, S. Kobayashi, Chem. Asian J., 2006, 1, 22
17. W. Verboom, Chem. Eng. Technol., 2009, 32, 1695
18. J. P. McMullen, K. F. Jensen, Annu. Rev. Anal. Chem., 2010, 3, 19
19. K. Tanaka, K. Fukase, Org. Process Res. Dev., 2009, 13, 983
20. D. M. Roberge, B. Zimmermann, F. Rainone, M. Gottsponer, M. Eyholzer, N. Kockmann, Org. Process Res. Dev., 2008, 12, 905
21. G. Jas, A. Kirschning, Chem. Eur. J., 2003, 9, 5708
22. A. Kirschning and G. Jas, Immobilized Catalysts, in Top. Curr. Chem., ed. A. Kirschning, 2004, p. 209
23. I. R. Baxendale and S. V. Ley, in New Avenues to Efficient Chemical Synthesis Emerging Technologies, ed. P. H. Seeberger and T. Blume, Springer, Berlin, Heidelberg, 2007, p. 151
24. S. Ceylan and A. Kirschning, in Recoverable and Recyclable Catalysts, ed. M. Benaglia, John Wiley & Sons Ltd., 2009, ch. 13, p. 379
25. J. Yoshida, A. Nagaki, T. Yamada, Chem. Eur. J., 2008, 14, 7450
26. J. P. McMullen, K. F. Jensen, Annu. Rev. Anal. Chem., 2010, 3, 19
27. K. Geyer, J. D. C. Codee, P. H. Seeberger, Chem. Eur. J., 2006, 12, 8434
28. A. Kirschning, W. Solodenko, K. Mennecke, Chem. Eur. J., 2006, 12, 5972
29. Handbook of Micro Reactors, ed. V. Hessel, J. C. Schouten, A. Renken, Y. Wang and J.-i. Yoshida, Wiley-VCH, Weinheim, 2009 in Microreactors in Organic Synthesis and Catalysis, ed. T. Wirth, Wiley-VCH, Weinheim, Germany, 2008, ch. 5, pp. 211-275
30. N. Kockmann, M. Gottsponer, B. Zimmermann, D. M. Roberge, Chem. Eur. J., 2008, 14, 7470
31. J. P. McMullen, M. T. Stone, S. L. Buchwald, K. F. Jensen, Angew. Chem., 2010, 39, 7230
32. Angew. Chem., Int. Ed., 2010, 49, 7076
33. V. Hessel, H. Löwe, Chem. Eng. Technol., 2005, 28, 267
34. T. Razzaq, C. O. Kappe, Chem. Asian J., 2010, 5, 1274
35. U. Kunz, T. Turek, Beilstein J. Org. Chem., 2009, 5, 70
36. T. N. Glasnov, C. O. Kappe, Eur. J. Org. Chem., 2009, 1321
37. G. Anitescu, A. Deshpande, L. L. Tavlarides, Energy Fuels, 2008, 22, 1391
38. C. Yan, J. Fraga-Dubeuil, E. Garcia-Verdugo, P. A. Hamley, M. Poliakoff, I. Pearson, A. Suart Coote, Green Chem., 2008, 10, 98
39. A. Michrowska, K. Mennecke, U. Kunz, A. Kirschning, K. Grela, J. Am. Chem. Soc., 2006, 128, 13261
40. T. N. Glasnov, D. J. Vugts, M. M. Koningstein, B. Desai, W. M. F. Fabian, R. V. A. Orru, C. O. Kappe, QSAR Comb. Sci., 2006, 25, 509
41. G. Shore, W.-J. Yoo, C.-J. Li, M. G. Organ, Chem. Eur. J., 2010, 16, 126
42. S. Ceylan, C. Friese, C. Lammel, K. Mazac, A. Kirschning, Angew. Chem., 2008, 120, 9083
43. Angew. Chem., Int. Ed., 2008, 47, 8950
44. S. Ceylan, L. Coutable, J. Wegner, A. Kirschning, Chem. Eur. J., 2011, 17, 1884
45. J. Wegner, S. Ceylan, C. Friese, A. Kirschning, Eur. J. Org. Chem., 2010, 4372
46. M. Baumann, I. R. Baxendale, S. V. Ley, Synlett, 2008, 2111
47. M. Baumann, I. R. Baxendale, L. J. Martin, S. V. Ley, Tetrahedron, 2009, 65, 6611
48. R. D. Chambers, D. Holling, R. C. H. Spink, G. Sandford, Lab Chip, 2001, 1, 132
49. R. D. Chambers, M. A. Fox, G. Sandford, Lab Chip, 2005, 5, 1132
50. C. B. McPake, C. B. Murray, G. Sandford, Tetrahedron Lett., 2009, 50, 1674
51. S. Hübner, U. Bentrup, U. Budde, K. Lovis, T. Dietrich, A. Freitag, L. Küpper, K. Jähnisch, Org. Process Res. Dev., 2009, 13, 952
52. M. O'Brien, I. R. Baxendale, S. V. Ley, Org. Lett., 2010, 12, 1596
53. A. Nagaki, N. Takabayashi, Y. Tomida, Y.-i. Yoshida, Beilstein J. Org. Chem., 2009, 5, 16
54. C. D. Keith, U.S. Patent 3,441,381, Apparatus for purifying exhaust gases of an internal combustion engine, April 29, 1969
55. F. Svec, J. M. J. Frechet, Science, 1996, 273, 205
56. D. A. Hickman, L. D. Schmidt, Science, 1993, 259, 343
57. A. Kirschning, U. Jas and G. Kunz, Chemistry in flow—new continuous flow reactors in organic synthesis, Innovation and Perspectives, in Solid Phase Synthesis and Combinatorial Libraries, ed. R. Epton, MPG Book Ltd., Kingswindford, UK, 2004
58. F. Svec, C. G. Huber, Anal. Chem., 2006, 78, 2100
59. A. Kirschning, C. Altwicker, G. Dräger, J. Harders, N. Hoffmann, U. Hoffmann, H. Schönfeld, W. Solodenko, U. Kunz, Angew. Chem., Int. Ed., 2001, 40, 3995
60. Angew. Chem., 2001, 113, 4118
61. M. Baumann, I. R. Baxendale, S. V. Ley, N. Nikbin, C. D. Smith, Org. Biomol. Chem., 2008, 6, 1587
62. N. Wang, T. Matsumoto, M. Ueno, H. Miyamura, S. Kobayashi, Angew. Chem., Int. Ed., 2009, 48, 4744
63. D. Popa, R. Marcos, S. Sayalero, A. Vidal-Ferran, M. A. Pericàs, Adv. Synth. Catal., 2009, 351, 1539
64. M. A. Pericàs, C. I. Herrerías, L. Solà, Adv. Synth. Catal., 2008, 350, 927
65. E. Alza, C. Rodríguez-Escrich, S. Sayalero, A. Bastero, M. A. Pericàs, Chem. Eur. J., 2009, 15, 10167
66. J. Rolland, X. C. Cambeiro, C. Rodríguez-Escrich, M. A. Pericàs, Beilstein J. Org. Chem., 2009, 5, 56
67. E. Alza, S. Sayalero, X. C. Cambeiro, R. Martín-Rapún, P. O. Miranda, M. A. Pericàs, Synlett, 2011, 464
68. E. Alza, C. Rodríguez-Escrich, S. Sayalero, A. Bastero, M. A. Pericàs, Chem. Eur. J., 2009, 15, 10167
69. J. E. Biggs-Houk, A. Younai, J. T. Shaw, Curr. Opin. Chem. Biol., 2010, 3, 371
70. B. B Toure, D. G. Hall, Chem. Rev., 2009, 109, 4439
71. L. Kürti and B. Czako, Strategic Applications of Named Reactions in Organic Synthesis, Elsevier Academic Press, Burlington, MA, 2005
72. B. Khanetsky, D. Dallinger, C. O. Kappe, J. Comb. Chem., 2004, 6, 884
73. W. S. Bremner, M. G. Organ, J. Comb. Chem., 2007, 9, 14
74. S.-J. Tu, Y. Zhang, H. Jiang, B. Jiang, J.-Yong Zhang, R.-H. Jia, F. Shi, Eur. J. Org. Chem., 2007, 1522
75. E. E. Coyle, M. Oelgemöller, Photochem. Photobiol. Sci., 2008, 7, 1313
76. Y. Matushita, T. Ichimura, N. Ohba, S. Kumada, K. Sakeda, T. Suzuki, H. Tanibata, T. Murata, Pure Appl. Chem., 2007, 79, 1959
77. A. A. Lapkin, V. M. Boddu, G. N. Aliev, B. Goller, S. Polisski, D. Kovalev, Chem. Eng. J., 2008, 136, 331
78. H. W. Chen, Y. Ku, A. Irawan, Chemosphere, 2007, 69, 184
79. A. Sugimoto, T. Fukuyama, Y. Sumino, M. Takagi, I. Ryu, Tetrahedron, 2009, 65, 1593
80. G. Takei, T. Kitamori, H. B. Kim, Catal. Commun., 2005, 6, 357
81. B. D. A. Hook, W. Dohle, P. R. Hirst, M. Pickworth, M. B. Berry, K. I. Booker-Milburn, J. Org. Chem., 2005, 70, 7558-7564
82. T. P. Petersen, A. Ritzen, T. Ulven, Org. Lett., 2009, 11, 5134
83. I. R. Baxendale, J. Deeley, C. M. Griffiths-Jones, S. V. Ley, S. Saaby, G. K. Tranmer, Chem. Commun., 2006, 2566
84. V. Hessel, presented at the 1st RSC/SCI Symposium on Continuous Processing and Flow Chemistry, 3rd 4th November 2010