A novel approach for stress-induced gastritis based on paradoxical anti-oxidative and anti-inflammatory action of exogenous 8-hydroxydeoxyguanosine

Biochemical Pharmacology

Volumn 81, Issue 1, 2011, Pages 111-122

  Ock, Chan Young ^a   Hong, Kyung Sook ^a   Choi, Ki Seok ^a   Chung, Myung Hee ^b   Kim, Yun soo ^c   Kim, Ju Hyun ^c   Hahm, Ki Baik ^a,c  

^a Gachon University College of Medicine   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c CHA Bundang Medical Center   (South Korea)

Author keywords

8 Hydroxydeoxyguanosine; NADPH oxidase; Oxidative stress; Rac GTP; Water immersion restraint stress

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CD31 ANTIGEN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; PHOSPHATIDYLINOSITOL 3 KINASE; RAC PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ELECTRON SPIN RESONANCE; ENZYME ACTIVATION; GASTRITIS; HUMAN; HUMAN CELL; HYPOXIA; IMMOBILIZATION STRESS; IMMUNOCYTOCHEMISTRY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WATER IMMERSION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CELL LINE; DEOXYGUANOSINE; GASTRITIS; HUMANS; MALE; MICE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SPECIFIC PATHOGEN-FREE ORGANISMS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION, GENETIC;

EID: 78549280110     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.08.023     Document Type: Article

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