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Volumn 90, Issue 3, 2012, Pages 269-278

LF immunomodulatory strategies: Mastering bacterial endotoxin

Author keywords

Immune response; Inflammation; Lactoferrin; Lipopolysaccharide

Indexed keywords

BACTERIAL ENDOTOXINS; BIOLOGICAL FLUIDS; CELLULAR COMPONENTS; COMPLEX INTERACTION; IMMUNE ACTIVATION; IMMUNE RESPONSE; INFLAMMATION; INFLAMMATORY RESPONSE; INNATE IMMUNE SYSTEMS; IRON BINDING; LACTOFERRIN; LIPOPOLYSACCHARIDES; MOLECULAR BASIS; PROINFLAMMATORY; THERAPEUTIC INTERVENTION; TISSUE DAMAGE;

EID: 84861394265     PISSN: 08298211     EISSN: 12086002     Source Type: Journal    
DOI: 10.1139/o11-059     Document Type: Review
Times cited : (36)

References (94)
  • 1
    • 77951225235 scopus 로고    scopus 로고
    • Human lactoferrin activates NF-κB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling
    • 10.1111/j.1742-4658.2010.07620.x 20345905
    • Ando K. Hasegawa K. Shindo K. Furusawa T. Fujino T. Kikugawa K. et al. 2010. Human lactoferrin activates NF-κB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling. FEBS J. 277 (9): 2051-2066. 10.1111/j.1742-4658.2010.07620.x 20345905
    • (2010) FEBS J. , vol.277 , Issue.9 , pp. 2051-2066
    • Ando, K.1    Hasegawa, K.2    Shindo, K.3    Furusawa, T.4    Fujino, T.5    Kikugawa, K.6
  • 2
    • 12744263109 scopus 로고    scopus 로고
    • Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide
    • 10.1042/BJ20041270 15344905
    • Andr J. Lohner K. Blondelle S.E. Jerala R. Moriyon I. Koch M.H. et al. 2005. Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem. J. 385 (1): 135 - 143. 10.1042/BJ20041270 15344905
    • (2005) Biochem. J. , vol.385 , Issue.1 , pp. 135-143
    • Andr, J.1    Lohner, K.2    Blondelle, S.E.3    Jerala, R.4    Moriyon, I.5    Koch, M.H.6
  • 4
    • 2942629621 scopus 로고    scopus 로고
    • Effects of lactoferrin on IL-6 production by peritoneal and alveolar cells in cyclophosphamide-treated mice
    • 15216955
    • Artym J. Zimecki M. Kruzel M.L. 2004. Effects of lactoferrin on IL-6 production by peritoneal and alveolar cells in cyclophosphamide-treated mice. J. Chemother. 16 (2): 187-192. 15216955
    • (2004) J. Chemother. , vol.16 , Issue.2 , pp. 187-192
    • Artym, J.1    Zimecki, M.2    Kruzel, M.L.3
  • 5
    • 0028641617 scopus 로고
    • Three-dimensional structure of lactoferrin in various functional states
    • 10.1007/978-1-4615-2548-6-1 7762421
    • Baker E.N. Anderson B.F. Baker H.M. Day C.L. Haridas M. Norris G.E. et al. 1994. Three-dimensional structure of lactoferrin in various functional states. Adv. Exp. Med. Biol. 357: 1-12. 10.1007/978-1-4615-2548-6-1 7762421
    • (1994) Adv. Exp. Med. Biol. , vol.357 , pp. 1-12
    • Baker, E.N.1    Anderson, B.F.2    Baker, H.M.3    Day, C.L.4    Haridas, M.5    Norris, G.E.6
  • 6
    • 24944504306 scopus 로고    scopus 로고
    • Biological effects of milk proteins and their peptides with emphasis on those related to the gastrointestinal ecosystem
    • 10.1017/S002202990500110X 16180723
    • Baldi A. Ioannis P. Chiara P. Eleonora F. Roubini C. Vittorio D. 2005. Biological effects of milk proteins and their peptides with emphasis on those related to the gastrointestinal ecosystem. J. Dairy Res. 72 (Suppl. 1): 66-72. 10.1017/S002202990500110X 16180723
    • (2005) J. Dairy Res. , vol.72 , Issue.SUPPL. 1 , pp. 66-72
    • Baldi, A.1    Ioannis, P.2    Chiara, P.3    Eleonora, F.4    Roubini, C.5    Vittorio, D.6
  • 7
    • 0034598975 scopus 로고    scopus 로고
    • Lactoferrin inhibits the binding of lipopolysaccharides to L-selectin and subsequent production of reactive oxygen species by neutrophils
    • a. 10.1016/S0014-5793(00)01243-6 10708745
    • Baveye S. Elass E. Mazurier J. Legrand D. 2000 a. Lactoferrin inhibits the binding of lipopolysaccharides to L-selectin and subsequent production of reactive oxygen species by neutrophils. FEBS Lett. 469 (1): 5-8. 10.1016/S0014-5793(00)01243-6 10708745
    • (2000) FEBS Lett. , vol.469 , Issue.1 , pp. 5-8
    • Baveye, S.1    Elass, E.2    Mazurier, J.3    Legrand, D.4
  • 8
    • 0034440799 scopus 로고    scopus 로고
    • Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex
    • b. 10.1128/IAI.68.12.6519-6525.2000 11083760
    • Baveye S. Elass E. Fernig D.G. Blanquart C. Mazurier J. Legrand D. 2000 b. Human lactoferrin interacts with soluble CD14 and inhibits expression of endothelial adhesion molecules, E-selectin and ICAM-1, induced by the CD14-lipopolysaccharide complex. Infect. Immun. 68 (12): 6519-6525. 10.1128/IAI.68.12.6519-6525.2000 11083760
    • (2000) Infect. Immun. , vol.68 , Issue.12 , pp. 6519-6525
    • Baveye, S.1    Elass, E.2    Fernig, D.G.3    Blanquart, C.4    Mazurier, J.5    Legrand, D.6
  • 9
    • 33748418054 scopus 로고    scopus 로고
    • Lactoferrin downregulates pro-inflammatory cytokines upexpressed in intestinal epithelial cells infected with invasive or noninvasive Escherichia coli strains
    • 10.1139/o06-039 16936806
    • Berlutti F. Schippa S. Morea C. Sarli S. Perfetto B. Donnarumma G. Valenti P. 2006. Lactoferrin downregulates pro-inflammatory cytokines upexpressed in intestinal epithelial cells infected with invasive or noninvasive Escherichia coli strains. Biochem. Cell Biol. 84 (3): 351-357. 10.1139/o06-039 16936806
    • (2006) Biochem. Cell Biol. , vol.84 , Issue.3 , pp. 351-357
    • Berlutti, F.1    Schippa, S.2    Morea, C.3    Sarli, S.4    Perfetto, B.5    Donnarumma, G.6    Valenti, P.7
  • 10
    • 0037317763 scopus 로고    scopus 로고
    • Innate immune sensing and its roots: The story of endotoxin
    • 10.1038/nri1004 12563300
    • Beutler B. Rietschel E.T. 2003. Innate immune sensing and its roots: the story of endotoxin. Nat. Rev. Immunol. 3 (2): 169-176. 10.1038/nri1004 12563300
    • (2003) Nat. Rev. Immunol. , vol.3 , Issue.2 , pp. 169-176
    • Beutler, B.1    Rietschel, E.T.2
  • 11
    • 0030712478 scopus 로고    scopus 로고
    • Conformational studies of synthetic lipid A analogues and partial structures by infrared spectroscopy
    • 10.1016/S0005-2736(97)00109-0 9370256
    • Brandenburg K. Kusumoto S. Seydel U. 1997. Conformational studies of synthetic lipid A analogues and partial structures by infrared spectroscopy. Biochim. Biophys. Acta, 1329 (1): 183-201. 10.1016/S0005-2736(97)00109-0 9370256
    • (1997) Biochim. Biophys. Acta , vol.1329 , Issue.1 , pp. 183-201
    • Brandenburg, K.1    Kusumoto, S.2    Seydel, U.3
  • 12
    • 0034834482 scopus 로고    scopus 로고
    • Biophysical characterization of lipopolysaccharide and lipid A inactivation by lactoferrin
    • 10.1515/BC.2001.152 11592403
    • Brandenburg K. Jurgens G. Muller M. Fukuoka S. Koch M.H. 2001. Biophysical characterization of lipopolysaccharide and lipid A inactivation by lactoferrin. Biol. Chem. 382 (8): 1215-1225. 10.1515/BC.2001.152 11592403
    • (2001) Biol. Chem. , vol.382 , Issue.8 , pp. 1215-1225
    • Brandenburg, K.1    Jurgens, G.2    Muller, M.3    Fukuoka, S.4    Koch, M.H.5
  • 13
    • 0020508495 scopus 로고
    • The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum. Unusual resistance of human apolactoferrin to proteolytic digestion
    • 10.1016/0304-4165(83)90317-3 6349699
    • Brines R.D. Brock J.H. 1983. The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum. Unusual resistance of human apolactoferrin to proteolytic digestion. Biochim. Biophys. Acta, 759 (3): 229-235. 10.1016/0304-4165(83)90317-3 6349699
    • (1983) Biochim. Biophys. Acta , vol.759 , Issue.3 , pp. 229-235
    • Brines, R.D.1    Brock, J.H.2
  • 14
    • 0035451425 scopus 로고    scopus 로고
    • Lactoferrin binds CpG-containing oligonucleotides and inhibits their immunostimulatory effects on human B cells
    • 11509640
    • Britigan B.E. Lewis T.S. Waldschmidt M. McCormick M.L. Krieg A.M. 2001. Lactoferrin binds CpG-containing oligonucleotides and inhibits their immunostimulatory effects on human B cells. J. Immunol. 167 (5): 2921-2928. 11509640
    • (2001) J. Immunol. , vol.167 , Issue.5 , pp. 2921-2928
    • Britigan, B.E.1    Lewis, T.S.2    Waldschmidt, M.3    McCormick, M.L.4    Krieg, A.M.5
  • 15
    • 33750183408 scopus 로고    scopus 로고
    • A complex of lactoferrin with monophosphoryl lipid A is an efficient adjuvant of the humoral and cellular immune response in mice
    • 10.1007/s00430-006-0020-3 16838169
    • Chodaczek G. Zimecki M. Lukasiewicz J. Lugowski C. 2006. A complex of lactoferrin with monophosphoryl lipid A is an efficient adjuvant of the humoral and cellular immune response in mice. Med. Microbiol. Immunol. (Berl.), 195 (4): 207-216. 10.1007/s00430-006-0020-3 16838169
    • (2006) Med. Microbiol. Immunol. (Berl.) , vol.195 , Issue.4 , pp. 207-216
    • Chodaczek, G.1    Zimecki, M.2    Lukasiewicz, J.3    Lugowski, C.4
  • 16
    • 0033453189 scopus 로고    scopus 로고
    • Effect of lactoferrin on the production of tumor necrosis factor-alpha and nitric oxide
    • 2000. 10.1002/(SICI)1097-4644(20000101)76:1<30: AID-JCB4>3.0.CO;2-U 10580998
    • Choe Y.-H. Lee S.-W. 2000. Effect of lactoferrin on the production of tumor necrosis factor-alpha and nitric oxide. J. Cell. Biochem. 76 (1): 30-36. 10.1002/(SICI)1097-4644(20000101)76:1<30::AID-JCB4>3.0.CO;2-U 10580998
    • J. Cell. Biochem. , vol.76 , Issue.1 , pp. 30-36
    • Choe, Y.-H.1    Lee, S.-W.2
  • 17
    • 0026463507 scopus 로고
    • Interaction of lactoferrin and lipopolysaccharide (LPS): Effects on the antioxidant property of lactoferrin and the ability of LPS to prime human neutrophils for enhanced superoxide formation
    • 10.1093/infdis/166.6.1375 1331250
    • Cohen M.S. Mao J. Rasmussen G.T. Serody J.S. Britigan B.E. 1992. Interaction of lactoferrin and lipopolysaccharide (LPS): effects on the antioxidant property of lactoferrin and the ability of LPS to prime human neutrophils for enhanced superoxide formation. J. Infect. Dis. 166 (6): 1375-1378. 10.1093/infdis/166.6.1375 1331250
    • (1992) J. Infect. Dis. , vol.166 , Issue.6 , pp. 1375-1378
    • Cohen, M.S.1    Mao, J.2    Rasmussen, G.T.3    Serody, J.S.4    Britigan, B.E.5
  • 18
    • 0034740796 scopus 로고    scopus 로고
    • Antiinflammatory activities of lactoferrin
    • discussion 396S - 397S. 11603648
    • Conneely O.M. 2001. Antiinflammatory activities of lactoferrin. J. Am. Coll. Nutr. 20 (5 Suppl.): 389S-395S; discussion 396S-397S. 11603648
    • (2001) J. Am. Coll. Nutr. , vol.20 , Issue.5 SUPPL.
    • Conneely, O.M.1
  • 19
    • 0025356465 scopus 로고
    • Proteins of iron storage and transport
    • 10.1016/S0065-3233(08)60288-0 2195850
    • Crichton R.R. 1990. Proteins of iron storage and transport. Adv. Protein Chem. 40: 281-363. 10.1016/S0065-3233(08)60288-0 2195850
    • (1990) Adv. Protein Chem. , vol.40 , pp. 281-363
    • Crichton, R.R.1
  • 20
    • 0026716209 scopus 로고
    • Regulation of cytokine release from mononuclear cells by the iron-binding protein lactoferrin
    • 1535239
    • Crouch S.P. Slater K.J. Fletcher J. 1992. Regulation of cytokine release from mononuclear cells by the iron-binding protein lactoferrin. Blood, 80 (1): 235-240. 1535239
    • (1992) Blood , vol.80 , Issue.1 , pp. 235-240
    • Crouch, S.P.1    Slater, K.J.2    Fletcher, J.3
  • 21
    • 33845464963 scopus 로고    scopus 로고
    • Lactoferrin activates macrophages via TLR4-dependent and-independent signaling pathways
    • 10.1016/j.cellimm.2006.08.006 17034774
    • Curran C.S. Demick K.P. Mansfield J.M. 2006. Lactoferrin activates macrophages via TLR4-dependent and-independent signaling pathways. Cell. Immunol. 242 (1): 23-30. 10.1016/j.cellimm.2006.08.006 17034774
    • (2006) Cell. Immunol. , vol.242 , Issue.1 , pp. 23-30
    • Curran, C.S.1    Demick, K.P.2    Mansfield, J.M.3
  • 22
    • 52649097625 scopus 로고    scopus 로고
    • In vitro effects of lactoferrin on lipopolysaccharide-induced proliferation, gene expression, and prostanoid production by bovine peripheral blood mononuclear cells
    • 10.2460/ajvr.69.9.1164 18764689
    • Dawes M.E. Tyler J.W. Marsh A.E. Larson R.L. Steevens B.J. Lakritz J. 2008. In vitro effects of lactoferrin on lipopolysaccharide-induced proliferation, gene expression, and prostanoid production by bovine peripheral blood mononuclear cells. Am. J. Vet. Res. 69 (9): 1164-1170. 10.2460/ajvr.69.9.1164 18764689
    • (2008) Am. J. Vet. Res. , vol.69 , Issue.9 , pp. 1164-1170
    • Dawes, M.E.1    Tyler, J.W.2    Marsh, A.E.3    Larson, R.L.4    Steevens, B.J.5    Lakritz, J.6
  • 23
    • 0036129834 scopus 로고    scopus 로고
    • Lactoferrin inhibits the lipopolysaccharide-induced expression and proteoglycan-binding ability of interleukin-8 in human endothelial cells
    • 10.1128/IAI.70.4.1860-1866.2002 11895948
    • Elass E. Masson M. Mazurier J. Legrand D. 2002. Lactoferrin inhibits the lipopolysaccharide-induced expression and proteoglycan-binding ability of interleukin-8 in human endothelial cells. Infect. Immun. 70 (4): 1860-1866. 10.1128/IAI.70.4.1860-1866.2002 11895948
    • (2002) Infect. Immun. , vol.70 , Issue.4 , pp. 1860-1866
    • Elass, E.1    Masson, M.2    Mazurier, J.3    Legrand, D.4
  • 24
    • 0029620277 scopus 로고
    • Lactoferrin-lipopolysaccharide interaction: Involvement of the 28-34 loop region of human lactoferrin in the high-affinity binding to Escherichia coli 055B5 lipopolysaccharide
    • 8554529
    • Elass-Rochard E. Roseanu A. Legrand D. Trif M. Salmon V. Motas C. et al. 1995. Lactoferrin-lipopolysaccharide interaction: involvement of the 28-34 loop region of human lactoferrin in the high-affinity binding to Escherichia coli 055B5 lipopolysaccharide. Biochem. J. 312 (3): 839-845. 8554529
    • (1995) Biochem. J. , vol.312 , Issue.3 , pp. 839-845
    • Elass-Rochard, E.1    Roseanu, A.2    Legrand, D.3    Trif, M.4    Salmon, V.5    Motas, C.6
  • 25
    • 0031883875 scopus 로고    scopus 로고
    • Lactoferrin inhibits the endotoxin interaction with CD14 by competition with the lipopolysaccharide-binding protein
    • 9453600
    • Elass-Rochard E. Legrand D. Salmon V. Roseanu A. Trif M. Tobias P.S. et al. 1998. Lactoferrin inhibits the endotoxin interaction with CD14 by competition with the lipopolysaccharide-binding protein. Infect. Immun. 66 (2): 486-491. 9453600
    • (1998) Infect. Immun. , vol.66 , Issue.2 , pp. 486-491
    • Elass-Rochard, E.1    Legrand, D.2    Salmon, V.3    Roseanu, A.4    Trif, M.5    Tobias, P.S.6
  • 26
    • 0026095436 scopus 로고
    • Killing of Gram-negative bacteria by lactoferrin and lysozyme
    • 10.1172/JCI115407 1918365
    • Ellison R.T. 3rd Giehl T.J. 1991. Killing of Gram-negative bacteria by lactoferrin and lysozyme. J. Clin. Invest. 88 (4): 1080-1091. 10.1172/JCI115407 1918365
    • (1991) J. Clin. Invest. , vol.88 , Issue.4 , pp. 1080-1091
    • Ellison III, R.T.1    Giehl, T.J.2
  • 27
    • 13944262797 scopus 로고    scopus 로고
    • Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN-gp120 interaction
    • 10.1128/JVI.79.5.3009-3015.2005 15709021
    • Groot F. Geijtenbeek T.B. Sanders R.W. Baldwin C.E. Sanchez-Hernandez M. Floris R. et al. 2005. Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN-gp120 interaction. J. Virol. 79 (5): 3009-3015. 10.1128/JVI.79.5.3009-3015.2005 15709021
    • (2005) J. Virol. , vol.79 , Issue.5 , pp. 3009-3015
    • Groot, F.1    Geijtenbeek, T.B.2    Sanders, R.W.3    Baldwin, C.E.4    Sanchez-Hernandez, M.5    Floris, R.6
  • 28
    • 0031845193 scopus 로고    scopus 로고
    • Protective function of proteins and lipids in human milk
    • 10.1159/000014021 9691157
    • Hamosh M. 1998. Protective function of proteins and lipids in human milk. Biol. Neonate, 74 (2): 163-176. 10.1159/000014021 9691157
    • (1998) Biol. Neonate , vol.74 , Issue.2 , pp. 163-176
    • Hamosh, M.1
  • 29
    • 0028813886 scopus 로고
    • Structure of human diferric lactoferrin refined at 2.2 Åresolution
    • 10.1107/S0907444994013521 15299793
    • Haridas M. Anderson B.F. Baker E.N. 1995. Structure of human diferric lactoferrin refined at 2.2 Åresolution. Acta Crystallogr. D Biol. Crystallogr. 51 (5): 629-646. 10.1107/S0907444994013521 15299793
    • (1995) Acta Crystallogr. D Biol. Crystallogr. , vol.51 , Issue.5 , pp. 629-646
    • Haridas, M.1    Anderson, B.F.2    Baker, E.N.3
  • 30
    • 17744405513 scopus 로고    scopus 로고
    • Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-κ B
    • 10.1016/S0008-8749(03)00006-6 12657243
    • HÄversen L. Ohlsson B.G. Hahn-Zoric M. Hanson L.A. Mattsby-Baltzer I. 2002. Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-κ B. Cell. Immunol. 220 (2): 83-95. 10.1016/S0008-8749(03)00006-6 12657243
    • (2002) Cell. Immunol. , vol.220 , Issue.2 , pp. 83-95
    • Häversen, L.1    Ohlsson, B.G.2    Hahn-Zoric, M.3    Hanson, L.A.4    Mattsby-Baltzer, I.5
  • 31
    • 2342507611 scopus 로고    scopus 로고
    • Oral administration of lactoferrin inhibits inflammation and nociception in rat adjuvant-induced arthritis
    • 10.1292/jvms.66.149 15031542
    • Hayashida K. Kaneko T. Takeuchi T. Shimizu H. Ando K. Harada E. 2004. Oral administration of lactoferrin inhibits inflammation and nociception in rat adjuvant-induced arthritis. J. Vet. Med. Sci. 66 (2): 149-154. 10.1292/jvms.66.149 15031542
    • (2004) J. Vet. Med. Sci. , vol.66 , Issue.2 , pp. 149-154
    • Hayashida, K.1    Kaneko, T.2    Takeuchi, T.3    Shimizu, H.4    Ando, K.5    Harada, E.6
  • 32
    • 0036065342 scopus 로고    scopus 로고
    • Initial responses to endotoxins and Gram-negative bacteria
    • 10.1016/S0009-8981(02)00180-8 12135807
    • Heumann D. Roger T. 2002. Initial responses to endotoxins and Gram-negative bacteria. Clin. Chim. Acta, 323 (1-2): 59-72. 10.1016/S0009- 8981(02)00180-8 12135807
    • (2002) Clin. Chim. Acta , vol.323 , Issue.12 , pp. 59-72
    • Heumann, D.1    Roger, T.2
  • 33
    • 77957999206 scopus 로고    scopus 로고
    • Human trial of liposomal lactoferrin supplementation for periodontal disease
    • 10.1248/bpb.33.1758 20930389
    • Ishikado A. Uesaki S. Suido H. Nomura Y. Sumikawa K. Maeda M. et al. 2010. Human trial of liposomal lactoferrin supplementation for periodontal disease. Biol. Pharm. Bull. 33 (10): 1758-1762. 10.1248/bpb.33.1758 20930389
    • (2010) Biol. Pharm. Bull. , vol.33 , Issue.10 , pp. 1758-1762
    • Ishikado, A.1    Uesaki, S.2    Suido, H.3    Nomura, Y.4    Sumikawa, K.5    Maeda, M.6
  • 34
    • 34948836847 scopus 로고    scopus 로고
    • Effect of lactoferrin in patients with chronic hepatitis C: Combination therapy with interferon and ribavirin
    • 10.1111/j.1440-1746.2007.04858.x 17914966
    • Kaito M. Iwasa M. Fujita N. Kobayashi Y. Kojima Y. Ikoma J. et al. 2007. Effect of lactoferrin in patients with chronic hepatitis C: combination therapy with interferon and ribavirin. J. Gastroenterol. Hepatol. 22 (11): 1894-1897. 10.1111/j.1440-1746.2007.04858.x 17914966
    • (2007) J. Gastroenterol. Hepatol. , vol.22 , Issue.11 , pp. 1894-1897
    • Kaito, M.1    Iwasa, M.2    Fujita, N.3    Kobayashi, Y.4    Kojima, Y.5    Ikoma, J.6
  • 35
    • 0026425505 scopus 로고
    • Specific binding of lactoferrin to Aeromonas hydrophila
    • 10.1111/j.1574-6968.1991.tb04399.x 1778417
    • Kishore A.R. Erdei J. Naidu S.S. Falsen E. Forsgren A. Naidu A.S. 1991. Specific binding of lactoferrin to Aeromonas hydrophila. FEMS Microbiol. Lett. 83 (1): 115-119. 10.1111/j.1574-6968.1991.tb04399.x 1778417
    • (1991) FEMS Microbiol. Lett. , vol.83 , Issue.1 , pp. 115-119
    • Kishore, A.R.1    Erdei, J.2    Naidu, S.S.3    Falsen, E.4    Forsgren, A.5    Naidu, A.S.6
  • 36
    • 0033976996 scopus 로고    scopus 로고
    • Lactoferrin protects gut mucosal integrity during endotoxemia induced by lipopolysaccharide in mice
    • 10.1023/A:1006935908960 10704062
    • Kruzel M.L. Harari Y. Chen C.Y. Castro G.A. 2000. Lactoferrin protects gut mucosal integrity during endotoxemia induced by lipopolysaccharide in mice. Inflammation, 24 (1): 33-44. 10.1023/A:1006935908960 10704062
    • (2000) Inflammation , vol.24 , Issue.1 , pp. 33-44
    • Kruzel, M.L.1    Harari, Y.2    Chen, C.Y.3    Castro, G.A.4
  • 37
    • 0036379733 scopus 로고    scopus 로고
    • Differential effects of prophylactic, concurrent and therapeutic lactoferrin treatment on LPS-induced inflammatory responses in mice
    • 10.1046/j.1365-2249.2002.01956.x 12296849
    • Kruzel M.L. Harari Y. Mailman D. Actor J.K. Zimecki M. 2002. Differential effects of prophylactic, concurrent and therapeutic lactoferrin treatment on LPS-induced inflammatory responses in mice. Clin. Exp. Immunol. 130 (1): 25-31. 10.1046/j.1365-2249.2002.01956.x 12296849
    • (2002) Clin. Exp. Immunol. , vol.130 , Issue.1 , pp. 25-31
    • Kruzel, M.L.1    Harari, Y.2    Mailman, D.3    Actor, J.K.4    Zimecki, M.5
  • 38
    • 77952395053 scopus 로고    scopus 로고
    • Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model
    • 10.1177/1753425909105317 19723832
    • Kruzel M.L. Actor J.K. Radak Z. Bacsi A. Saavedra-Molina A. Boldogh I. 2010. Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model. Innate Immun. 16 (2): 67-79. 10.1177/1753425909105317 19723832
    • (2010) Innate Immun. , vol.16 , Issue.2 , pp. 67-79
    • Kruzel, M.L.1    Actor, J.K.2    Radak, Z.3    Bacsi, A.4    Saavedra-Molina, A.5    Boldogh, I.6
  • 39
    • 0032038664 scopus 로고    scopus 로고
    • The protective effects of lactoferrin feeding against endotoxin lethal shock in germfree piglets
    • 9529062
    • Lee W.J. Farmer J.L. Hilty M. Kim Y.B. 1998. The protective effects of lactoferrin feeding against endotoxin lethal shock in germfree piglets. Infect. Immun. 66 (4): 1421-1426. 9529062
    • (1998) Infect. Immun. , vol.66 , Issue.4 , pp. 1421-1426
    • Lee, W.J.1    Farmer, J.L.2    Hilty, M.3    Kim, Y.B.4
  • 40
    • 77953286718 scopus 로고    scopus 로고
    • A critical review of the roles of host lactoferrin in immunity
    • 10.1007/s10534-010-9297-1 20143251
    • Legrand D. Mazurier J. 2010. A critical review of the roles of host lactoferrin in immunity. Biometals, 23 (3): 365-376. 10.1007/s10534-010-9297-1 20143251
    • (2010) Biometals , vol.23 , Issue.3 , pp. 365-376
    • Legrand, D.1    Mazurier, J.2
  • 41
    • 0030663974 scopus 로고    scopus 로고
    • The N-terminal Arg2, Arg3 and Arg4 of human lactoferrin interact with sulphated molecules but not with the receptor present on Jurkat human lymphoblastic T-cells
    • 9581564
    • Legrand D. van Berkel P.H. Salmon V. van Veen H.A. Slomianny M.C. Nuijens J.H. Spik G. 1997. The N-terminal Arg2, Arg3 and Arg4 of human lactoferrin interact with sulphated molecules but not with the receptor present on Jurkat human lymphoblastic T-cells. Biochem. J. 327 (Pt 3): 841-846. 9581564
    • (1997) Biochem. J. , vol.327 , Issue.PART 3 , pp. 841-846
    • Legrand, D.1    Van Berkel, P.H.2    Salmon, V.3    Van Veen, H.A.4    Slomianny, M.C.5    Nuijens, J.H.6    Spik, G.7
  • 42
    • 28444462150 scopus 로고    scopus 로고
    • Lactoferrin: A modulator of immune and inflammatory responses
    • 10.1007/s00018-005-5370-2 16261255
    • Legrand D. Elass E. Carpentier M. Mazurier J. 2005. Lactoferrin: a modulator of immune and inflammatory responses. Cell. Mol. Life Sci. 62 (22): 2549-2559. 10.1007/s00018-005-5370-2 16261255
    • (2005) Cell. Mol. Life Sci. , vol.62 , Issue.22 , pp. 2549-2559
    • Legrand, D.1    Elass, E.2    Carpentier, M.3    Mazurier, J.4
  • 44
    • 0031684157 scopus 로고    scopus 로고
    • Synergic antistaphylococcal properties of lactoferrin and lysozyme
    • 10.1099/00222615-47-9-837 9736166
    • Leitch E.C. Willcox M.D. 1998. Synergic antistaphylococcal properties of lactoferrin and lysozyme. J. Med. Microbiol. 47 (9): 837-842. 10.1099/00222615-47-9-837 9736166
    • (1998) J. Med. Microbiol. , vol.47 , Issue.9 , pp. 837-842
    • Leitch, E.C.1    Willcox, M.D.2
  • 45
    • 43049179999 scopus 로고    scopus 로고
    • LPS/TLR4 signal transduction pathway
    • 10.1016/j.cyto.2008.01.006 18304834
    • Lu Y.C. Yeh W.C. Ohashi P.S. 2008. LPS/TLR4 signal transduction pathway. Cytokine, 42 (2): 145-151. 10.1016/j.cyto.2008.01.006 18304834
    • (2008) Cytokine , vol.42 , Issue.2 , pp. 145-151
    • Lu, Y.C.1    Yeh, W.C.2    Ohashi, P.S.3
  • 46
    • 0027515007 scopus 로고
    • Lactoferrin regulates the release of tumour necrosis factor alpha and interleukin 6 in vivo
    • 8217778
    • Machnicki M. Zimecki M. Zagulski T. 1993. Lactoferrin regulates the release of tumour necrosis factor alpha and interleukin 6 in vivo. Int. J. Exp. Pathol. 74 (5): 433-439. 8217778
    • (1993) Int. J. Exp. Pathol. , vol.74 , Issue.5 , pp. 433-439
    • MacHnicki, M.1    Zimecki, M.2    Zagulski, T.3
  • 47
    • 0027978954 scopus 로고
    • Delineation of the glycosaminoglycan-binding site in the human inflammatory response protein lactoferrin
    • 8089135
    • Mann D.M. Romm E. Migliorini M. 1994. Delineation of the glycosaminoglycan-binding site in the human inflammatory response protein lactoferrin. J. Biol. Chem. 269 (38): 23661-23667. 8089135
    • (1994) J. Biol. Chem. , vol.269 , Issue.38 , pp. 23661-23667
    • Mann, D.M.1    Romm, E.2    Migliorini, M.3
  • 48
    • 0029888252 scopus 로고    scopus 로고
    • Lactoferrin or a fragment thereof inhibits the endotoxin-induced interleukin-6 response in human monocytic cells
    • 10.1203/00006450-199608000-00011 8827774
    • Mattsby-Baltzer I. Roseanu A. Motas C. Elverfors J. Engberg I. Hanson L.A. 1996. Lactoferrin or a fragment thereof inhibits the endotoxin-induced interleukin-6 response in human monocytic cells. Pediatr. Res. 40 (2): 257-262. 10.1203/00006450-199608000-00011 8827774
    • (1996) Pediatr. Res. , vol.40 , Issue.2 , pp. 257-262
    • Mattsby-Baltzer, I.1    Roseanu, A.2    Motas, C.3    Elverfors, J.4    Engberg, I.5    Hanson, L.A.6
  • 49
    • 0025674182 scopus 로고
    • CDNA and protein sequence of bovine lactoferrin
    • 10.1093/nar/18.23.7167 2263492
    • Mead P.E. Tweedie J.W. 1990. cDNA and protein sequence of bovine lactoferrin. Nucleic Acids Res. 18 (23): 7167. 10.1093/nar/18.23.7167 2263492
    • (1990) Nucleic Acids Res. , vol.18 , Issue.23 , pp. 7167
    • Mead, P.E.1    Tweedie, J.W.2
  • 50
    • 0021677758 scopus 로고
    • Human lactotransferrin: Amino acid sequence and structural comparisons with other transferrins
    • 10.1111/j.1432-1033.1984.tb08607.x 6510420
    • Metz-Boutigue M.H. Jolles J. Mazurier J. Schoentgen F. Legrand D. Spik G. et al. 1984. Human lactotransferrin: amino acid sequence and structural comparisons with other transferrins. Eur. J. Biochem. 145 (3): 659-676. 10.1111/j.1432-1033.1984.tb08607.x 6510420
    • (1984) Eur. J. Biochem. , vol.145 , Issue.3 , pp. 659-676
    • Metz-Boutigue, M.H.1    Jolles, J.2    Mazurier, J.3    Schoentgen, F.4    Legrand, D.5    Spik, G.6
  • 51
    • 0034064838 scopus 로고    scopus 로고
    • Effect of lactoferrin on lipopolysaccharide (LPS) induced preterm delivery in mice
    • 10.1080/j.1600-0412.2000.079005355.x 10830761
    • Mitsuhashi Y. Otsuki K. Yoda A. Shimizu Y. Saito H. Yanaihara T. 2000. Effect of lactoferrin on lipopolysaccharide (LPS) induced preterm delivery in mice. Acta Obstet. Gynecol. Scand. 79 (5): 355-358. 10.1080/j.1600-0412.2000. 079005355.x 10830761
    • (2000) Acta Obstet. Gynecol. Scand. , vol.79 , Issue.5 , pp. 355-358
    • Mitsuhashi, Y.1    Otsuki, K.2    Yoda, A.3    Shimizu, Y.4    Saito, H.5    Yanaihara, T.6
  • 52
    • 0026036144 scopus 로고
    • Lactoferrin-lipopolysaccharide interactions. Effect on lactoferrin binding to monocyte/macrophage-differentiated HL-60 cells
    • 1702815
    • Miyazawa K. Mantel C. Lu L. Morrison D.C. Broxmeyer H.E. 1991. Lactoferrin-lipopolysaccharide interactions. Effect on lactoferrin binding to monocyte/macrophage-differentiated HL-60 cells. J. Immunol. 146 (2): 723-729. 1702815
    • (1991) J. Immunol. , vol.146 , Issue.2 , pp. 723-729
    • Miyazawa, K.1    Mantel, C.2    Lu, L.3    Morrison, D.C.4    Broxmeyer, H.E.5
  • 53
    • 0030719461 scopus 로고    scopus 로고
    • Three-dimensional structure of diferric bovine lactoferrin at 2.8 Å resolution
    • 10.1006/jmbi.1997.1386 9398529
    • Moore S.A. Anderson B.F. Groom C.R. Haridas M. Baker E.N. 1997. Three-dimensional structure of diferric bovine lactoferrin at 2.8 Å resolution. J. Mol. Biol. 274 (2): 222-236. 10.1006/jmbi.1997.1386 9398529
    • (1997) J. Mol. Biol. , vol.274 , Issue.2 , pp. 222-236
    • Moore, S.A.1    Anderson, B.F.2    Groom, C.R.3    Haridas, M.4    Baker, E.N.5
  • 54
    • 19044385630 scopus 로고    scopus 로고
    • Detoxifying endotoxin: Time, place and person
    • 15949133
    • Munford R.S. 2005. Detoxifying endotoxin: time, place and person. J. Endotoxin Res. 11 (2): 69-84. 15949133
    • (2005) J. Endotoxin Res. , vol.11 , Issue.2 , pp. 69-84
    • Munford, R.S.1
  • 55
    • 3142610871 scopus 로고    scopus 로고
    • Lactoferrin works as a new LPS-binding protein in inflammatory activation of macrophages
    • 10.1016/j.intimp.2004.05.009 15251114
    • Na Y.J. Han S.B. Kang J.S. Yoon Y.D. Park S.K. Kim H.M. et al. 2004. Lactoferrin works as a new LPS-binding protein in inflammatory activation of macrophages. Int. Immunopharmacol. 4 (9): 1187-1199. 10.1016/j.intimp.2004.05. 009 15251114
    • (2004) Int. Immunopharmacol. , vol.4 , Issue.9 , pp. 1187-1199
    • Na, Y.J.1    Han, S.B.2    Kang, J.S.3    Yoon, Y.D.4    Park, S.K.5    Kim, H.M.6
  • 56
    • 0026347239 scopus 로고
    • Specific binding of lactoferrin to Escherichia coli isolated from human intestinal infections
    • 10.1111/j.1699-0463.1991.tb01311.x 1772651
    • Naidu S.S. Erdei J. Czirók E. Kalfas S. Gadó I. Thorén A. et al. 1991. Specific binding of lactoferrin to Escherichia coli isolated from human intestinal infections. APMIS, 99 (7-12): 1142-1150. 10.1111/j.1699-0463.1991.tb01311.x 1772651
    • (1991) APMIS , vol.99 , Issue.712 , pp. 1142-1150
    • Naidu, S.S.1    Erdei, J.2    Czirók, E.3    Kalfas, S.4    Gadó, I.5    Thorén, A.6
  • 57
    • 58149105930 scopus 로고    scopus 로고
    • The influence of lactoferrin, orally administered, on systemic iron homeostasis in pregnant women suffering of iron deficiency and iron deficiency anaemia
    • 10.1016/j.biochi.2008.06.004 18601971
    • Paesano R. Pietropaoli M. Gessani S. Valenti P. 2009. The influence of lactoferrin, orally administered, on systemic iron homeostasis in pregnant women suffering of iron deficiency and iron deficiency anaemia. Biochimie, 91 (1): 44-51. 10.1016/j.biochi.2008.06.004 18601971
    • (2009) Biochimie , vol.91 , Issue.1 , pp. 44-51
    • Paesano, R.1    Pietropaoli, M.2    Gessani, S.3    Valenti, P.4
  • 58
    • 0025980055 scopus 로고
    • Molecular cloning and sequence analysis of bovine lactotransferrin
    • 10.1111/j.1432-1033.1991.tb15801.x 2001696
    • Pierce A. Colavizza D. Benaissa M. Maes P. Tartar A. Montreuil J. Spik G. 1991. Molecular cloning and sequence analysis of bovine lactotransferrin. Eur. J. Biochem. 196 (1): 177-184. 10.1111/j.1432-1033.1991.tb15801.x 2001696
    • (1991) Eur. J. Biochem. , vol.196 , Issue.1 , pp. 177-184
    • Pierce, A.1    Colavizza, D.2    Benaissa, M.3    Maes, P.4    Tartar, A.5    Montreuil, J.6    Spik, G.7
  • 59
    • 34547741667 scopus 로고    scopus 로고
    • Role of endogenous interferon and LPS in the immunomodulatory effects of bovine lactoferrin in murine peritoneal macrophages
    • 10.1189/jlb.1106688 17475783
    • Puddu P. Carollo M.G. Belardelli F. Valenti P. Gessani S. 2007. Role of endogenous interferon and LPS in the immunomodulatory effects of bovine lactoferrin in murine peritoneal macrophages. J. Leukoc. Biol. 82 (2): 347-353. 10.1189/jlb.1106688 17475783
    • (2007) J. Leukoc. Biol. , vol.82 , Issue.2 , pp. 347-353
    • Puddu, P.1    Carollo, M.G.2    Belardelli, F.3    Valenti, P.4    Gessani, S.5
  • 60
    • 58149140244 scopus 로고    scopus 로고
    • Immunomodulatory effects of lactoferrin on antigen presenting cells
    • 10.1016/j.biochi.2008.05.005 18539153
    • Puddu P. Valenti P. Gessani S. 2009. Immunomodulatory effects of lactoferrin on antigen presenting cells. Biochimie, 91 (1): 11-18. 10.1016/j.biochi.2008.05.005 18539153
    • (2009) Biochimie , vol.91 , Issue.1 , pp. 11-18
    • Puddu, P.1    Valenti, P.2    Gessani, S.3
  • 61
    • 77953290149 scopus 로고    scopus 로고
    • Immunoregulatory role of lactoferrin-lipopolysaccharide interactions
    • 10.1007/s10534-010-9307-3 20191308
    • Puddu P. Latorre D. Valenti P. Gessani S. 2010. Immunoregulatory role of lactoferrin-lipopolysaccharide interactions. Biometals, 23 (3): 387-397. 10.1007/s10534-010-9307-3 20191308
    • (2010) Biometals , vol.23 , Issue.3 , pp. 387-397
    • Puddu, P.1    Latorre, D.2    Valenti, P.3    Gessani, S.4
  • 62
    • 79960724573 scopus 로고    scopus 로고
    • Bovine lactoferrin counteracts Toll-like receptor mediated activation signals in antigen presenting cells
    • 10.1371/journal.pone.0022504 21799877
    • Puddu P. Latorre D. Carollo M.G. Catizone A. Ricci G. Valenti P. Gessani S. 2011. Bovine lactoferrin counteracts Toll-like receptor mediated activation signals in antigen presenting cells. PLoS ONE, 6 (7): e22504. 10.1371/journal.pone.0022504 21799877
    • (2011) PLoS ONE , vol.6 , Issue.7 , pp. 22504
    • Puddu, P.1    Latorre, D.2    Carollo, M.G.3    Catizone, A.4    Ricci, G.5    Valenti, P.6    Gessani, S.7
  • 63
    • 0027435157 scopus 로고
    • A critical role for monocytes and CD14 in endotoxin-induced endothelial cell activation
    • a. 10.1084/jem.178.6.2193 7504060
    • Pugin J. Ulevitch R.J. Tobias P.S. 1993 a. A critical role for monocytes and CD14 in endotoxin-induced endothelial cell activation. J. Exp. Med. 178 (6): 2193-2200. 10.1084/jem.178.6.2193 7504060
    • (1993) J. Exp. Med. , vol.178 , Issue.6 , pp. 2193-2200
    • Pugin, J.1    Ulevitch, R.J.2    Tobias, P.S.3
  • 64
    • 0027446922 scopus 로고
    • Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14
    • b. 10.1073/pnas.90.7.2744 7681988
    • Pugin J. Schurer-Maly C.C. Leturcq D. Moriarty A. Ulevitch R.J. Tobias P.S. 1993 b. Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc. Natl. Acad. Sci. U.S.A. 90 (7): 2744-2748. 10.1073/pnas.90.7.2744 7681988
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , Issue.7 , pp. 2744-2748
    • Pugin, J.1    Schurer-Maly, C.C.2    Leturcq, D.3    Moriarty, A.4    Ulevitch, R.J.5    Tobias, P.S.6
  • 66
    • 0028609661 scopus 로고
    • Kinetic parameters for the heat denaturation of bovine lactoferrin in milk, and its effect on interaction with monocytes
    • 10.1007/978-1-4615-2548-6-27 7762440
    • Sánchez L. Peiró J.M. Oria R. Castillo H. Brock J.H. Calvo M. 1994. Kinetic parameters for the heat denaturation of bovine lactoferrin in milk, and its effect on interaction with monocytes. Adv. Exp. Med. Biol. 357: 253-257. 10.1007/978-1-4615-2548-6-27 7762440
    • (1994) Adv. Exp. Med. Biol. , vol.357 , pp. 253-257
    • Sánchez, L.1    Peiró, J.M.2    Oria, R.3    Castillo, H.4    Brock, J.H.5    Calvo, M.6
  • 67
    • 7644241949 scopus 로고    scopus 로고
    • Preventive effect of recombinant human lactoferrin on lipopolysaccharide-induced preterm delivery in mice
    • 15488117
    • Sasaki Y. Otsuki K. Hasegawa A. Sawada M. Chiba H. Negishi M. et al. 2004. Preventive effect of recombinant human lactoferrin on lipopolysaccharide- induced preterm delivery in mice. Acta Obstet. Gynecol. Scand. 83 (11): 1035-1038. 15488117
    • (2004) Acta Obstet. Gynecol. Scand. , vol.83 , Issue.11 , pp. 1035-1038
    • Sasaki, Y.1    Otsuki, K.2    Hasegawa, A.3    Sawada, M.4    Chiba, H.5    Negishi, M.6
  • 68
    • 0001654207 scopus 로고    scopus 로고
    • Biological activities of lipopolysaccharides are determined by the shape of their lipid A portion
    • 10.1046/j.1432-1327.2000.01204.x 10727940
    • Schromm A.B. Brandenburg K. Loppnow H. Moran A.P. Koch M.H. Rietschel E.T. Seydel U. 2000. Biological activities of lipopolysaccharides are determined by the shape of their lipid A portion. Eur. J. Biochem. 267 (7): 2008-2013. 10.1046/j.1432-1327.2000.01204.x 10727940
    • (2000) Eur. J. Biochem. , vol.267 , Issue.7 , pp. 2008-2013
    • Schromm, A.B.1    Brandenburg, K.2    Loppnow, H.3    Moran, A.P.4    Koch, M.H.5    Rietschel, E.T.6    Seydel, U.7
  • 69
    • 0025107568 scopus 로고
    • Structure and function of lipopolysaccharide binding protein
    • 10.1126/science.2402637 2402637
    • Schumann R.R. Leong S.R. Flaggs G.W. Gray P.W. Wright S.D. Mathison J.C. et al. 1990. Structure and function of lipopolysaccharide binding protein. Science, 249 (4975): 1429-1431. 10.1126/science.2402637 2402637
    • (1990) Science , vol.249 , Issue.4975 , pp. 1429-1431
    • Schumann, R.R.1    Leong, S.R.2    Flaggs, G.W.3    Gray, P.W.4    Wright, S.D.5    Mathison, J.C.6
  • 70
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
    • 10.1084/jem.189.11.1777 10359581
    • Shimazu R. Akashi S. Ogata H. Nagai Y. Fukudome K. Miyake K. Kimoto M. 1999. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189 (11): 1777-1782. 10.1084/jem.189.11.1777 10359581
    • (1999) J. Exp. Med. , vol.189 , Issue.11 , pp. 1777-1782
    • Shimazu, R.1    Akashi, S.2    Ogata, H.3    Nagai, Y.4    Fukudome, K.5    Miyake, K.6    Kimoto, M.7
  • 71
    • 0024119835 scopus 로고
    • Comparative study of the primary structures of sero-, lacto-and ovotransferrin glycans from different species
    • 10.1016/0300-9084(88)90283-0 3149515
    • Spik G. Coddeville B. Montreuil J. 1988. Comparative study of the primary structures of sero-, lacto-and ovotransferrin glycans from different species. Biochimie, 70 (11): 1459-1469. 10.1016/0300-9084(88)90283-0 3149515
    • (1988) Biochimie , vol.70 , Issue.11 , pp. 1459-1469
    • Spik, G.1    Coddeville, B.2    Montreuil, J.3
  • 72
    • 34249787889 scopus 로고    scopus 로고
    • Bovine lactoferrin protects lipopolysaccharide-induced diarrhea modulating nitric oxide and prostaglandin E2 in mice
    • 10.1139/Y07-004 17487261
    • Talukder M.J. Harada E. 2007. Bovine lactoferrin protects lipopolysaccharide-induced diarrhea modulating nitric oxide and prostaglandin E2 in mice. Can. J. Physiol. Pharmacol. 85 (2): 200-208. 10.1139/Y07-004 17487261
    • (2007) Can. J. Physiol. Pharmacol. , vol.85 , Issue.2 , pp. 200-208
    • Talukder, M.J.1    Harada, E.2
  • 73
    • 77953292320 scopus 로고    scopus 로고
    • Evaluation of the cytoprotective effects of bovine lactoferrin against intestinal toxins using cellular model systems
    • 10.1007/s10534-010-9301-9 20157763
    • Tian H. Maddox I.S. Ferguson L.R. Shu Q. 2010. Evaluation of the cytoprotective effects of bovine lactoferrin against intestinal toxins using cellular model systems. Biometals, 23 (3): 589-592. 10.1007/s10534-010-9301-9 20157763
    • (2010) Biometals , vol.23 , Issue.3 , pp. 589-592
    • Tian, H.1    Maddox, I.S.2    Ferguson, L.R.3    Shu, Q.4
  • 74
    • 58149127827 scopus 로고    scopus 로고
    • Twenty-five years of research on bovine lactoferrin applications
    • 10.1016/j.biochi.2008.05.021 18585434
    • Tomita M. Wakabayashi H. Shin K. Yamauchi K. Yaeshima T. Iwatsuki K. 2009. Twenty-five years of research on bovine lactoferrin applications. Biochimie, 91 (1): 52-57. 10.1016/j.biochi.2008.05.021 18585434
    • (2009) Biochimie , vol.91 , Issue.1 , pp. 52-57
    • Tomita, M.1    Wakabayashi, H.2    Shin, K.3    Yamauchi, K.4    Yaeshima, T.5    Iwatsuki, K.6
  • 75
    • 77953270296 scopus 로고    scopus 로고
    • Cancer prevention by bovine lactoferrin: From animal studies to human trial
    • 10.1007/s10534-010-9331-3 20407806
    • Tsuda H. Kozu T. Iinuma G. Ohashi Y. Saito Y. Saito D. et al. 2010. Cancer prevention by bovine lactoferrin: from animal studies to human trial. Biometals, 23 (3): 399-409. 10.1007/s10534-010-9331-3 20407806
    • (2010) Biometals , vol.23 , Issue.3 , pp. 399-409
    • Tsuda, H.1    Kozu, T.2    Iinuma, G.3    Ohashi, Y.4    Saito, Y.5    Saito, D.6
  • 76
    • 34147170948 scopus 로고    scopus 로고
    • Effect of lactoferrin supplementation on the effectiveness and tolerability of a 7-day quadruple therapy after failure of a first attempt to cure Helicobacter pylori infection
    • 17392649
    • Tursi A. Elisei W. Brandimarte G. Giorgetti G.M. Modeo M.E. Aiello F. 2007. Effect of lactoferrin supplementation on the effectiveness and tolerability of a 7-day quadruple therapy after failure of a first attempt to cure Helicobacter pylori infection. Med. Sci. Monit. 13 (4): CR187-CR190. 17392649
    • (2007) Med. Sci. Monit. , vol.13 , Issue.4
    • Tursi, A.1    Elisei, W.2    Brandimarte, G.3    Giorgetti, G.M.4    Modeo, M.E.5    Aiello, F.6
  • 77
    • 28344457682 scopus 로고    scopus 로고
    • Lactoferrin: An important host defence against microbial and viral attack
    • 10.1007/s00018-005-5372-0 16261253
    • Valenti P. Antonini G. 2005. Lactoferrin: an important host defence against microbial and viral attack. Cell. Mol. Life Sci. 62 (22): 2576-2587. 10.1007/s00018-005-5372-0 16261253
    • (2005) Cell. Mol. Life Sci. , vol.62 , Issue.22 , pp. 2576-2587
    • Valenti, P.1    Antonini, G.2
  • 78
    • 1342322699 scopus 로고    scopus 로고
    • The role of N-linked glycosylation in the protection of human and bovine lactoferrin against tryptic proteolysis
    • 10.1111/j.1432-1033.2003.03965.x 14764083
    • van Veen H.A. Geerts M.E. van Berkel P.H. Nuijens J.H. 2004. The role of N-linked glycosylation in the protection of human and bovine lactoferrin against tryptic proteolysis. Eur. J. Biochem. 271 (4): 678-684. 10.1111/j.1432-1033. 2003.03965.x 14764083
    • (2004) Eur. J. Biochem. , vol.271 , Issue.4 , pp. 678-684
    • Van Veen, H.A.1    Geerts, M.E.2    Van Berkel, P.H.3    Nuijens, J.H.4
  • 79
    • 0032777423 scopus 로고    scopus 로고
    • Lactoferrin inhibits HIV-1 replication in vitro and exhibits synergy when combined with zidovudine
    • 10.1097/00002030-199907090-00018 10416533
    • Viani R.M. Gutteberg T.J. Lathey J.L. Spector S.A. 1999. Lactoferrin inhibits HIV-1 replication in vitro and exhibits synergy when combined with zidovudine. AIDS, 13 (10): 1273-1274. 10.1097/00002030-199907090-00018 10416533
    • (1999) AIDS , vol.13 , Issue.10 , pp. 1273-1274
    • Viani, R.M.1    Gutteberg, T.J.2    Lathey, J.L.3    Spector, S.A.4
  • 80
    • 0021119501 scopus 로고
    • Comparative studies on the chemical and immunochemical properties of human milk, human pancreatic juice and bovine milk lactoferrin
    • 10.1016/0305-0491(84)90100-7 6434227
    • Wang C.S. Chan W.Y. Kloer H.U. 1984. Comparative studies on the chemical and immunochemical properties of human milk, human pancreatic juice and bovine milk lactoferrin. Comp. Biochem. Physiol. B, 78 (3): 575-580. 10.1016/0305-0491(84)90100-7 6434227
    • (1984) Comp. Biochem. Physiol. B , vol.78 , Issue.3 , pp. 575-580
    • Wang, C.S.1    Chan, W.Y.2    Kloer, H.U.3
  • 81
    • 0029009708 scopus 로고
    • Lipopolysaccharide-inactivating activity of neutrophils is due to lactoferrin
    • 7790769
    • Wang D. Pabst K.M. Aida Y. Pabst M.J. 1995. Lipopolysaccharide- inactivating activity of neutrophils is due to lactoferrin. J. Leukoc. Biol. 57 (6): 865-874. 7790769
    • (1995) J. Leukoc. Biol. , vol.57 , Issue.6 , pp. 865-874
    • Wang, D.1    Pabst, K.M.2    Aida, Y.3    Pabst, M.J.4
  • 82
    • 28344447990 scopus 로고    scopus 로고
    • Multifunctional roles of lactoferrin: A critical overview
    • 10.1007/s00018-005-5369-8 16261256
    • Ward P.P. Paz E. Conneely O.M. 2005. Multifunctional roles of lactoferrin: a critical overview. Cell. Mol. Life Sci. 62 (22): 2540-2548. 10.1007/s00018-005-5369-8 16261256
    • (2005) Cell. Mol. Life Sci. , vol.62 , Issue.22 , pp. 2540-2548
    • Ward, P.P.1    Paz, E.2    Conneely, O.M.3
  • 83
    • 0034166581 scopus 로고    scopus 로고
    • Presence of a glycan at a potential N-glycosylation site, Asn-281, of bovine lactoferrin
    • 10.3168/jds.S0022-0302(00)74929-0 10791783
    • Wei Z. Nishimura T. Yoshida S. 2000. Presence of a glycan at a potential N-glycosylation site, Asn-281, of bovine lactoferrin. J. Dairy Sci. 83 (4): 683-689. 10.3168/jds.S0022-0302(00)74929-0 10791783
    • (2000) J. Dairy Sci. , vol.83 , Issue.4 , pp. 683-689
    • Wei, Z.1    Nishimura, T.2    Yoshida, S.3
  • 84
    • 0019496335 scopus 로고
    • Bacterial lipopolysaccharide and its lipid A component: Some historical and some current aspects
    • 7274542
    • Westphal O. Luderitz O. Rietschel E.T. Galanos C. 1981. Bacterial lipopolysaccharide and its lipid A component: some historical and some current aspects. Biochem. Soc. Trans. 9 (3): 191-195. 7274542
    • (1981) Biochem. Soc. Trans. , vol.9 , Issue.3 , pp. 191-195
    • Westphal, O.1    Luderitz, O.2    Rietschel, E.T.3    Galanos, C.4
  • 85
    • 0029053828 scopus 로고
    • CD14 and innate recognition of bacteria
    • 7541427
    • Wright S.D. 1995. CD14 and innate recognition of bacteria. J. Immunol. 155 (1): 6-8. 7541427
    • (1995) J. Immunol. , vol.155 , Issue.1 , pp. 6-8
    • Wright, S.D.1
  • 86
    • 0025166114 scopus 로고
    • CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
    • 10.1126/science.1698311 1698311
    • Wright S.D. Ramos R.A. Tobias P.S. Ulevitch R.J. Mathison J.C. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science, 249 (4975): 1431-1433. 10.1126/science.1698311 1698311
    • (1990) Science , vol.249 , Issue.4975 , pp. 1431-1433
    • Wright, S.D.1    Ramos, R.A.2    Tobias, P.S.3    Ulevitch, R.J.4    Mathison, J.C.5
  • 87
    • 0028901203 scopus 로고
    • Characterization of the glycosaminoglycan-binding region of lactoferrin
    • 10.1006/abbi.1995.1139 7872808
    • Wu H.F. Monroe D.M. Church F.C. 1995. Characterization of the glycosaminoglycan-binding region of lactoferrin. Arch. Biochem. Biophys. 317 (1): 85-92. 10.1006/abbi.1995.1139 7872808
    • (1995) Arch. Biochem. Biophys. , vol.317 , Issue.1 , pp. 85-92
    • Wu, H.F.1    Monroe, D.M.2    Church, F.C.3
  • 88
    • 31344478777 scopus 로고    scopus 로고
    • Intraperitoneal injection of lactoferrin ameliorates severe albumin extravasation and neutrophilia in LPS-induced inflammation in neonatal rats
    • 10.2220/biomedres.26.249 16415506
    • Yajima M. Yajima T. Kuwata T. 2005. Intraperitoneal injection of lactoferrin ameliorates severe albumin extravasation and neutrophilia in LPS-induced inflammation in neonatal rats. Biomed. Res. 26 (6): 249-255. 10.2220/biomedres.26.249 16415506
    • (2005) Biomed. Res. , vol.26 , Issue.6 , pp. 249-255
    • Yajima, M.1    Yajima, T.2    Kuwata, T.3
  • 89
    • 0034767215 scopus 로고    scopus 로고
    • Lactoferrin protects against development of hepatitis caused by sensitization of Kupffer cells by lipopolysaccharide
    • 11687469
    • Yamaguchi M. Matsuura M. Kobayashi K. Sasaki H. Yajima T. Kuwata T. 2001. Lactoferrin protects against development of hepatitis caused by sensitization of Kupffer cells by lipopolysaccharide. Clin. Diagn. Lab. Immunol. 8 (6): 1234-1239. 11687469
    • (2001) Clin. Diagn. Lab. Immunol. , vol.8 , Issue.6 , pp. 1234-1239
    • Yamaguchi, M.1    Matsuura, M.2    Kobayashi, K.3    Sasaki, H.4    Yajima, T.5    Kuwata, T.6
  • 90
    • 77955130666 scopus 로고    scopus 로고
    • Inhibitory effects of orally administrated liposomal bovine lactoferrin on the LPS-induced osteoclastogenesis
    • 10.1038/labinvest.2010.80 20421871
    • Yamano E. Miyauchi M. Furusyo H. Kawazoe A. Ishikado A. Makino T. et al. 2010. Inhibitory effects of orally administrated liposomal bovine lactoferrin on the LPS-induced osteoclastogenesis. Lab. Invest. 90 (8): 1236-1246. 10.1038/labinvest.2010.80 20421871
    • (2010) Lab. Invest. , vol.90 , Issue.8 , pp. 1236-1246
    • Yamano, E.1    Miyauchi, M.2    Furusyo, H.3    Kawazoe, A.4    Ishikado, A.5    Makino, T.6
  • 91
    • 79955934355 scopus 로고    scopus 로고
    • Lactoferrin inhibits the inflammatory and angiogenic activation of bovine aortic endothelial cells
    • 10.1007/s00011-010-0294-1 21161563
    • Yeom M. Park J. Lee B. Choi S.Y. Kim K.S. Lee H. Hahm D.H. 2011. Lactoferrin inhibits the inflammatory and angiogenic activation of bovine aortic endothelial cells. Inflamm. Res. 60 (5): 475-482. 10.1007/s00011-010-0294-1 21161563
    • (2011) Inflamm. Res. , vol.60 , Issue.5 , pp. 475-482
    • Yeom, M.1    Park, J.2    Lee, B.3    Choi, S.Y.4    Kim, K.S.5    Lee, H.6    Hahm, D.H.7
  • 92
    • 0034303264 scopus 로고    scopus 로고
    • Separation of lactoferrin - A and B from bovine colostrum
    • 10.3168/jds.S0022-0302(00)75104-6 11049060
    • Yoshida S. Wei Z. Shinmura Y. Fukunaga N. 2000. Separation of lactoferrin- A and-b from bovine colostrum. J. Dairy Sci. 83 (10): 2211-2215. 10.3168/jds.S0022-0302(00)75104-6 11049060
    • (2000) J. Dairy Sci. , vol.83 , Issue.10 , pp. 2211-2215
    • Yoshida, S.1    Wei, Z.2    Shinmura, Y.3    Fukunaga, N.4
  • 93
    • 0024842051 scopus 로고
    • Lactoferrin can protect mice against a lethal dose of Escherichia coli in experimental infection in vivo
    • 2690922
    • Zagulski T. Lipinski P. Zagulska A. Broniek S. Jarzabek Z. 1989. Lactoferrin can protect mice against a lethal dose of Escherichia coli in experimental infection in vivo. Br. J. Exp. Pathol. 70 (6): 697-704. 2690922
    • (1989) Br. J. Exp. Pathol. , vol.70 , Issue.6 , pp. 697-704
    • Zagulski, T.1    Lipinski, P.2    Zagulska, A.3    Broniek, S.4    Jarzabek, Z.5
  • 94
    • 0032975547 scopus 로고    scopus 로고
    • Neutralization of endotoxin in vitro and in vivo by a human lactoferrin-derived peptide
    • 10024582
    • Zhang G.H. Mann D.M. Tsai C.M. 1999. Neutralization of endotoxin in vitro and in vivo by a human lactoferrin-derived peptide. Infect. Immun. 67 (3): 1353-1358. 10024582
    • (1999) Infect. Immun. , vol.67 , Issue.3 , pp. 1353-1358
    • Zhang, G.H.1    Mann, D.M.2    Tsai, C.M.3


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