Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins

Oncotarget

Volumn 2, Issue 12, 2011, Pages 1176-1190

  Vainio, Paula ^a   Lehtinen, Laura ^a   Mirtti, Tuomas ^b,c,d   Hilvo, Mika ^e   Seppänen Laakso, Tuulikki ^e   Virtanen, Johannes ^a   Sankila, Anna ^d   Nordling, Stig ^d   Lundin, Johan ^c   Rannikko, Antti ^d   Orešič, Matej ^e   Kallioniemi, Olli ^a,c   Iljin, Kristiina ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^e VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

Biomarker; Drug target; PLA2G7; Prostate cancer; Statins

Indexed keywords

ALDEHYDE DEHYDROGENASE; ANTINEOPLASTIC AGENT; CASP3 PROTEIN, HUMAN; CASP7 PROTEIN, HUMAN; CASPASE 3; CASPASE 7; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LYSOPHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A2; PLA2G7 PROTEIN, HUMAN; SMALL INTERFERING RNA; TUMOR MARKER;

APOPTOSIS; ARTICLE; CANCER INVASION; CELL ADHESION; CELL MOTION; CELL PROLIFERATION; DISEASE COURSE; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MALE; METABOLISM; PATHOLOGY; PROSTATE TUMOR; RNA INTERFERENCE; TUMOR CELL LINE;

ALDEHYDE DEHYDROGENASE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 7; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DISEASE PROGRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LYSOPHOSPHATIDYLCHOLINES; MALE; NEOPLASM INVASIVENESS; PHOSPHOLIPASES A2; PROSTATIC NEOPLASMS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TUMOR MARKERS, BIOLOGICAL;

EID: 84861380745     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.397     Document Type: Article

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