-
2
-
-
0344631738
-
Ten-year survey of lung cancer treatment and survival in hospitals in the United States: a national cancer data base report
-
Fry WA, Phillips JL, Menck HR. Ten-year survey of lung cancer treatment and survival in hospitals in the United States: a national cancer data base report. Cancer 1999; 86: 1867-76.
-
(1999)
Cancer
, vol.86
, pp. 1867-1876
-
-
Fry, W.A.1
Phillips, J.L.2
Menck, H.R.3
-
3
-
-
0035951697
-
Molecular analysis of the mitotic checkpoint genes BUB1, BUBR1 and BUB3 in human lung cancers
-
Haruki N, Saito H, Harano T etal. Molecular analysis of the mitotic checkpoint genes BUB1, BUBR1 and BUB3 in human lung cancers. Cancer Lett 2001; 162: 201-5.
-
(2001)
Cancer Lett
, vol.162
, pp. 201-205
-
-
Haruki, N.1
Saito, H.2
Harano, T.3
-
4
-
-
15044341779
-
An overview of lung cancer genomics and proteomics
-
Granville CA, Dennis PA. An overview of lung cancer genomics and proteomics. Am J Respir Cell Mol Biol 2005; 32: 169-76.
-
(2005)
Am J Respir Cell Mol Biol
, vol.32
, pp. 169-176
-
-
Granville, C.A.1
Dennis, P.A.2
-
5
-
-
19844380235
-
Genomic and proteomic profiling of lung cancers: lung cancer classification in the age of targeted therapy
-
Meyerson M, Carbone D. Genomic and proteomic profiling of lung cancers: lung cancer classification in the age of targeted therapy. J Clin Oncol 2005; 23: 3219-26.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3219-3226
-
-
Meyerson, M.1
Carbone, D.2
-
6
-
-
77957970301
-
Epigenetic modifications and human disease
-
Portela A, Esteller M. Epigenetic modifications and human disease. Nat Biotechnol 2010; 28: 1057-68.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1057-1068
-
-
Portela, A.1
Esteller, M.2
-
7
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128: 683-92.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
8
-
-
13844320649
-
Aberrant DNA methylation as a cancer-inducing mechanism
-
Esteller M. Aberrant DNA methylation as a cancer-inducing mechanism. Annu Rev Pharmacol Toxicol 2005; 45: 629-56.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 629-656
-
-
Esteller, M.1
-
9
-
-
0344407016
-
Histone deacetylases: unique players in shaping the epigenetic histone code
-
Thiagalingam S, Cheng KH, Lee HJ etal. Histone deacetylases: unique players in shaping the epigenetic histone code. Ann N Y Acad Sci 2003; 983: 84-100.
-
(2003)
Ann N Y Acad Sci
, vol.983
, pp. 84-100
-
-
Thiagalingam, S.1
Cheng, K.H.2
Lee, H.J.3
-
10
-
-
78049403944
-
DNA methylation and non-small cell lung cancer
-
Zhang Y, Chen L. DNA methylation and non-small cell lung cancer. Zhongguo Fei Ai Za Zhi 2010; 13: 821-6.
-
(2010)
Zhongguo Fei Ai Za Zhi
, vol.13
, pp. 821-826
-
-
Zhang, Y.1
Chen, L.2
-
11
-
-
70449592216
-
Promoter hypermethylation of the p16 and Wif-1 genes as an independent prognostic marker in stage IA non-small cell lung cancers
-
Yoshino M, Suzuki M, Tian L etal. Promoter hypermethylation of the p16 and Wif-1 genes as an independent prognostic marker in stage IA non-small cell lung cancers. Int J Oncol 2009; 35: 1201-9.
-
(2009)
Int J Oncol
, vol.35
, pp. 1201-1209
-
-
Yoshino, M.1
Suzuki, M.2
Tian, L.3
-
12
-
-
77449124527
-
PTEN, RASSF1 and DAPK site-specific hypermethylation and outcome in surgically treated stage I and II nonsmall cell lung cancer patients
-
Buckingham L, Penfield Faber L, Kim A etal. PTEN, RASSF1 and DAPK site-specific hypermethylation and outcome in surgically treated stage I and II nonsmall cell lung cancer patients. Int J Cancer 2010; 126: 1630-9.
-
(2010)
Int J Cancer
, vol.126
, pp. 1630-1639
-
-
Buckingham, L.1
Penfield Faber, L.2
Kim, A.3
-
13
-
-
78049492101
-
Posttranscriptional regulation of PTEN dosage by noncoding RNAs
-
He L. Posttranscriptional regulation of PTEN dosage by noncoding RNAs. Sci Signal 2010; 3: pe39.
-
(2010)
Sci Signal
, vol.3
-
-
He, L.1
-
14
-
-
77956530122
-
Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A
-
Chen M, Voeller D, Marquez VE etal. Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A. Int J Oncol 2010; 37: 963-71.
-
(2010)
Int J Oncol
, vol.37
, pp. 963-971
-
-
Chen, M.1
Voeller, D.2
Marquez, V.E.3
-
16
-
-
77349116360
-
microRNA and lung cancer: tumors and 22-mers
-
Du L, Pertsemlidis A. microRNA and lung cancer: tumors and 22-mers. Cancer Metastasis Rev 2010; 29: 109-22.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 109-122
-
-
Du, L.1
Pertsemlidis, A.2
-
19
-
-
65649152994
-
MicroRNAs and lung cancer: new oncogenes and tumor suppressors, new prognostic factors and potential therapeutic targets
-
Ortholan C, Puissegur MP, Ilie M etal. MicroRNAs and lung cancer: new oncogenes and tumor suppressors, new prognostic factors and potential therapeutic targets. Curr Med Chem 2009; 16: 1047-61.
-
(2009)
Curr Med Chem
, vol.16
, pp. 1047-1061
-
-
Ortholan, C.1
Puissegur, M.P.2
Ilie, M.3
-
20
-
-
78650194092
-
let-7 and miR-17-92: small-sized major players in lung cancer development
-
Osada H, Takahashi T. let-7 and miR-17-92: small-sized major players in lung cancer development. Cancer Sci 2010; 102: 9-17.
-
(2010)
Cancer Sci
, vol.102
, pp. 9-17
-
-
Osada, H.1
Takahashi, T.2
-
21
-
-
33646598656
-
Small RNAs and non-small cell lung cancer
-
Tong AW. Small RNAs and non-small cell lung cancer. Curr Mol Med 2006; 6: 339-49.
-
(2006)
Curr Mol Med
, vol.6
, pp. 339-349
-
-
Tong, A.W.1
-
22
-
-
67649399383
-
Potential uses of microRNA in lung cancer diagnosis, prognosis, and therapy
-
Wang QZ, Xu W, Habib N etal. Potential uses of microRNA in lung cancer diagnosis, prognosis, and therapy. Curr Cancer Drug Targets 2009; 9: 572-94.
-
(2009)
Curr Cancer Drug Targets
, vol.9
, pp. 572-594
-
-
Wang, Q.Z.1
Xu, W.2
Habib, N.3
-
24
-
-
49749126791
-
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
-
Lodygin D, Tarasov V, Epanchintsev A etal. Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle 2008; 7: 2591-600.
-
(2008)
Cell Cycle
, vol.7
, pp. 2591-2600
-
-
Lodygin, D.1
Tarasov, V.2
Epanchintsev, A.3
-
25
-
-
74249123570
-
The miR-34 family in cancer and apoptosis
-
Hermeking H. The miR-34 family in cancer and apoptosis. Cell Death Differ 2010; 17: 193-9.
-
(2010)
Cell Death Differ
, vol.17
, pp. 193-199
-
-
Hermeking, H.1
-
26
-
-
34250868124
-
Differential regulation of microRNA by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest
-
Tarasov V, Jung P, Verdoodt B etal. Differential regulation of microRNA by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 2007; 6: 1586-93.
-
(2007)
Cell Cycle
, vol.6
, pp. 1586-1593
-
-
Tarasov, V.1
Jung, P.2
Verdoodt, B.3
-
27
-
-
34249822779
-
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
-
Raver-Shapira N, Marciano E, Meiri E etal. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol Cell 2007; 26: 731-43.
-
(2007)
Mol Cell
, vol.26
, pp. 731-743
-
-
Raver-Shapira, N.1
Marciano, E.2
Meiri, E.3
-
28
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
Fabbri M, Garzon R, Cimmino A etal. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci U S A 2007; 104: 15805-10.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
-
29
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-33.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
30
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNA
-
Gregory RI, Yan KP, Amuthan G etal. The Microprocessor complex mediates the genesis of microRNA. Nature 2004; 432: 235-40.
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
-
31
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet 2004; 5: 522-31.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
32
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee Y, Kim M, Han J etal. MicroRNA genes are transcribed by RNA polymerase II. EMBO J 2004; 23: 4051-60.
-
(2004)
EMBO J
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
-
35
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Guttinger S, Calado A etal. Nuclear export of microRNA precursors. Science 2004; 303: 95-8.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
-
36
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNA and short hairpin RNAs
-
Yi R, Qin Y, Macara IG etal. Exportin-5 mediates the nuclear export of pre-microRNA and short hairpin RNAs. Genes Dev 2003; 17: 3011-6.
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
-
37
-
-
22144461002
-
miRNA, cancer, and stem cell division
-
Croce CM, Calin GA. miRNA, cancer, and stem cell division. Cell 2005; 122: 6-7.
-
(2005)
Cell
, vol.122
, pp. 6-7
-
-
Croce, C.M.1
Calin, G.A.2
-
38
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
40
-
-
27544495514
-
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
-
Hayashita Y, Osada H, Tatematsu Y etal. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005; 65: 9628-32.
-
(2005)
Cancer Res
, vol.65
, pp. 9628-9632
-
-
Hayashita, Y.1
Osada, H.2
Tatematsu, Y.3
-
41
-
-
70349464806
-
Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers
-
Ebi H, Sato T, Sugito N etal. Counterbalance between RB inactivation and miR-17-92 overexpression in reactive oxygen species and DNA damage induction in lung cancers. Oncogene 2009; 28: 3371-9.
-
(2009)
Oncogene
, vol.28
, pp. 3371-3379
-
-
Ebi, H.1
Sato, T.2
Sugito, N.3
-
42
-
-
34447101200
-
Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92
-
Matsubara H, Takeuchi T, Nishikawa E etal. Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92. Oncogene 2007; 26: 6099-105.
-
(2007)
Oncogene
, vol.26
, pp. 6099-6105
-
-
Matsubara, H.1
Takeuchi, T.2
Nishikawa, E.3
-
43
-
-
78449268612
-
EGFR promotes lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF
-
Chou YT, Lin HH, Lien YC etal. EGFR promotes lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF. Cancer Res 2010; 70: 8822-31.
-
(2010)
Cancer Res
, vol.70
, pp. 8822-8831
-
-
Chou, Y.T.1
Lin, H.H.2
Lien, Y.C.3
-
44
-
-
77956501846
-
Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21
-
Hatley ME, Patrick DM, Garcia MR etal. Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21. Cancer Cell 2010; 18: 282-93.
-
(2010)
Cancer Cell
, vol.18
, pp. 282-293
-
-
Hatley, M.E.1
Patrick, D.M.2
Garcia, M.R.3
-
45
-
-
77956061393
-
MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)
-
Zhang JG, Wang JJ, Zhao F etal. MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC). Clin Chim Acta 2010; 411: 846-52.
-
(2010)
Clin Chim Acta
, vol.411
, pp. 846-852
-
-
Zhang, J.G.1
Wang, J.J.2
Zhao, F.3
-
46
-
-
79951771769
-
miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer
-
Foss KM, Sima C, Ugolini D etal. miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer. J Thorac Oncol 2011; 6: 482-8.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 482-488
-
-
Foss, K.M.1
Sima, C.2
Ugolini, D.3
-
47
-
-
78149463483
-
Cigarette smoke induces C/EBP-beta-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells
-
Xi S, Yang M, Tao Y etal. Cigarette smoke induces C/EBP-beta-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells. PLoS One 2010; 5: e13764.
-
(2010)
PLoS One
, vol.5
-
-
Xi, S.1
Yang, M.2
Tao, Y.3
-
48
-
-
77951154173
-
MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors
-
Liu X, Sempere LF, Ouyang H etal. MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. J Clin Invest 2010; 120: 1298-309.
-
(2010)
J Clin Invest
, vol.120
, pp. 1298-1309
-
-
Liu, X.1
Sempere, L.F.2
Ouyang, H.3
-
49
-
-
77953765642
-
The role of microRNA in human lung squamous cell carcinoma
-
Yang Y, Li X, Yang Q etal. The role of microRNA in human lung squamous cell carcinoma. Cancer Genet Cytogenet 2010; 200: 127-33.
-
(2010)
Cancer Genet Cytogenet
, vol.200
, pp. 127-133
-
-
Yang, Y.1
Li, X.2
Yang, Q.3
-
50
-
-
79953029421
-
MicroRNA-101 Exerts Tumor-Suppressive Functions in Non-small Cell Lung Cancer through Directly Targeting Enhancer of Zeste Homolog 2
-
Epub ahead of print]
-
Zhang JG, Guo JF, Liu DL etal. MicroRNA-101 Exerts Tumor-Suppressive Functions in Non-small Cell Lung Cancer through Directly Targeting Enhancer of Zeste Homolog 2. J Thorac Oncol 2011; [Epub ahead of print].
-
(2011)
J Thorac Oncol
-
-
Zhang, J.G.1
Guo, J.F.2
Liu, D.L.3
-
51
-
-
78549269168
-
miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc
-
Online publication
-
Chen Z, Zeng H, Guo Y etal. miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc. J Exp Clin Cancer Res 2010; 29. Online publication.
-
(2010)
J Exp Clin Cancer Res
, vol.29
-
-
Chen, Z.1
Zeng, H.2
Guo, Y.3
-
52
-
-
78149342035
-
Curcumin promotes apoptosis in human lung adenocarcinoma cells through miR-186* signaling pathway
-
Zhang J, Du Y, Wu C etal. Curcumin promotes apoptosis in human lung adenocarcinoma cells through miR-186* signaling pathway. Oncol Rep 2010; 24: 1217-23.
-
(2010)
Oncol Rep
, vol.24
, pp. 1217-1223
-
-
Zhang, J.1
Du, Y.2
Wu, C.3
-
53
-
-
77958516991
-
MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma
-
Davidson MR, Larsen JE, Yang IA etal. MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma. PLoS One 2010; 5: e12560.
-
(2010)
PLoS One
, vol.5
-
-
Davidson, M.R.1
Larsen, J.E.2
Yang, I.A.3
-
54
-
-
77952879648
-
Hsa-mir-182 suppresses lung tumorigenesis through down regulation of RGS17 expression in vitro
-
Sun Y, Fang R, Li C etal. Hsa-mir-182 suppresses lung tumorigenesis through down regulation of RGS17 expression in vitro. Biochem Biophys Res Commun 2010; 396: 501-7.
-
(2010)
Biochem Biophys Res Commun
, vol.396
, pp. 501-507
-
-
Sun, Y.1
Fang, R.2
Li, C.3
-
55
-
-
77951716642
-
miR-212 increases tumor necrosis factor-related apoptosis-inducing ligand sensitivity in non-small cell lung cancer by targeting the antiapoptotic protein PED
-
Incoronato M, Garofalo M, Urso L etal. miR-212 increases tumor necrosis factor-related apoptosis-inducing ligand sensitivity in non-small cell lung cancer by targeting the antiapoptotic protein PED. Cancer Res 2010; 70: 3638-46.
-
(2010)
Cancer Res
, vol.70
, pp. 3638-3646
-
-
Incoronato, M.1
Garofalo, M.2
Urso, L.3
-
56
-
-
73949116135
-
miR-126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7
-
Sun Y, Bai Y, Zhang F etal. miR-126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7. Biochem Biophys Res Commun 2010; 391: 1483-9.
-
(2010)
Biochem Biophys Res Commun
, vol.391
, pp. 1483-1489
-
-
Sun, Y.1
Bai, Y.2
Zhang, F.3
-
57
-
-
77953232823
-
The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice
-
He XY, Chen JX, Zhang Z etal. The let-7a microRNA protects from growth of lung carcinoma by suppression of k-Ras and c-Myc in nude mice. J Cancer Res Clin Oncol 2010; 136: 1023-8.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 1023-1028
-
-
He, X.Y.1
Chen, J.X.2
Zhang, Z.3
-
58
-
-
77949658280
-
Regression of murine lung tumors by the let-7 microRNA
-
Trang P, Medina PP, Wiggins JF etal. Regression of murine lung tumors by the let-7 microRNA. Oncogene 2010; 29: 1580-7.
-
(2010)
Oncogene
, vol.29
, pp. 1580-1587
-
-
Trang, P.1
Medina, P.P.2
Wiggins, J.F.3
-
59
-
-
77957280345
-
Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer
-
Ceppi P, Mudduluru G, Kumarswamy R etal. Loss of miR-200c expression induces an aggressive, invasive, and chemoresistant phenotype in non-small cell lung cancer. Mol Cancer Res 2010; 8: 1207-16.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 1207-1216
-
-
Ceppi, P.1
Mudduluru, G.2
Kumarswamy, R.3
-
60
-
-
78149462073
-
Use of microRNA expression levels to predict outcomes in resected stage I non-small cell lung cancer
-
Duncavage E, Goodgame B, Sezhiyan A etal. Use of microRNA expression levels to predict outcomes in resected stage I non-small cell lung cancer. J Thorac Oncol 2010; 5: 1755-63.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1755-1763
-
-
Duncavage, E.1
Goodgame, B.2
Sezhiyan, A.3
-
61
-
-
77955516533
-
Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers
-
Yu L, Todd NW, Xing L etal. Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers. Int J Cancer 2010; 12: 2870-8.
-
(2010)
Int J Cancer
, vol.12
, pp. 2870-2878
-
-
Yu, L.1
Todd, N.W.2
Xing, L.3
-
62
-
-
77950498821
-
Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer
-
Hu Z, Chen X, Zhao Y etal. Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J Clin Oncol 2010; 28: 1721-6.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1721-1726
-
-
Hu, Z.1
Chen, X.2
Zhao, Y.3
-
63
-
-
74549118209
-
Accurate classification of non-small cell lung carcinoma using a novel microRNA-based approach
-
Bishop JA, Benjamin H, Cholakh H etal. Accurate classification of non-small cell lung carcinoma using a novel microRNA-based approach. Clin Cancer Res 2010; 16: 610-9.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 610-619
-
-
Bishop, J.A.1
Benjamin, H.2
Cholakh, H.3
-
64
-
-
77955175327
-
Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers
-
Xing L, Todd NW, Yu L etal. Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers. Mod Pathol 2010; 23: 1157-64.
-
(2010)
Mod Pathol
, vol.23
, pp. 1157-1164
-
-
Xing, L.1
Todd, N.W.2
Yu, L.3
-
65
-
-
75149130928
-
Evaluation of microRNA expression profiles that may predict recurrence of localized stage I non-small cell lung cancer after surgical resection
-
Patnaik SK, Kannisto E, Knudsen S etal. Evaluation of microRNA expression profiles that may predict recurrence of localized stage I non-small cell lung cancer after surgical resection. Cancer Res 2010; 70: 36-45.
-
(2010)
Cancer Res
, vol.70
, pp. 36-45
-
-
Patnaik, S.K.1
Kannisto, E.2
Knudsen, S.3
-
66
-
-
77954316346
-
MicroRNA expression differentiates between primary lung tumors and metastases to the lung
-
Barshack I, Lithwick-Yanai G, Afek A etal. MicroRNA expression differentiates between primary lung tumors and metastases to the lung. Pathol Res Pract 2010; 206: 578-84.
-
(2010)
Pathol Res Pract
, vol.206
, pp. 578-584
-
-
Barshack, I.1
Lithwick-Yanai, G.2
Afek, A.3
-
67
-
-
78449296222
-
MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma
-
Voortman J, Goto A, Mendiboure J etal. MicroRNA expression and clinical outcomes in patients treated with adjuvant chemotherapy after complete resection of non-small cell lung carcinoma. Cancer Res 2010; 70: 8288-98.
-
(2010)
Cancer Res
, vol.70
, pp. 8288-8298
-
-
Voortman, J.1
Goto, A.2
Mendiboure, J.3
-
68
-
-
34748837455
-
Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples
-
Xi Y, Nakajima G, Gavin E etal. Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples. RNA 2007; 13: 1668-74.
-
(2007)
RNA
, vol.13
, pp. 1668-1674
-
-
Xi, Y.1
Nakajima, G.2
Gavin, E.3
-
69
-
-
75249103831
-
A personalized microRNA microarray normalization method using a logistic regression model
-
Wang B, Wang XF, Howell P etal. A personalized microRNA microarray normalization method using a logistic regression model. Bioinformatics 2010; 26: 228-34.
-
(2010)
Bioinformatics
, vol.26
, pp. 228-234
-
-
Wang, B.1
Wang, X.F.2
Howell, P.3
-
70
-
-
77957355926
-
Epigenetics and miRNA in human cancer
-
Fabbri M, Calin GA. Epigenetics and miRNA in human cancer. Adv Genet 2010; 70: 87-99.
-
(2010)
Adv Genet
, vol.70
, pp. 87-99
-
-
Fabbri, M.1
Calin, G.A.2
-
71
-
-
72849147757
-
Epigenetics, miRNA, and human cancer: a new chapter in human gene regulation
-
Valeri N, Vannini I, Fanini F etal. Epigenetics, miRNA, and human cancer: a new chapter in human gene regulation. Mamm Genome 2009; 20: 573-80.
-
(2009)
Mamm Genome
, vol.20
, pp. 573-580
-
-
Valeri, N.1
Vannini, I.2
Fanini, F.3
-
72
-
-
33947310031
-
Environmental epigenomics and disease susceptibility
-
Jirtle RL, Skinner MK. Environmental epigenomics and disease susceptibility. Nat Rev Genet 2007; 8: 253-62.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 253-262
-
-
Jirtle, R.L.1
Skinner, M.K.2
-
73
-
-
68949217876
-
Potential of DNMT and its epigenetic regulation for lung cancer therapy
-
Tang M, Xu W, Wang Q etal. Potential of DNMT and its epigenetic regulation for lung cancer therapy. Curr Genomics 2009; 10: 336-52.
-
(2009)
Curr Genomics
, vol.10
, pp. 336-352
-
-
Tang, M.1
Xu, W.2
Wang, Q.3
-
74
-
-
16044371662
-
Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M
-
Plass C, Shibata H, Kalcheva I etal. Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M. Nat Genet 1996; 14: 106-9.
-
(1996)
Nat Genet
, vol.14
, pp. 106-109
-
-
Plass, C.1
Shibata, H.2
Kalcheva, I.3
-
76
-
-
0037007175
-
Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases
-
Jeltsch A. Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases. Chembiochem 2002; 3: 274-93.
-
(2002)
Chembiochem
, vol.3
, pp. 274-293
-
-
Jeltsch, A.1
-
77
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003; 349: 2042-54.
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
78
-
-
34248217444
-
Methylation of human microRNA genes in normal and neoplastic cells
-
Weber B, Stresemann C, Brueckner B etal. Methylation of human microRNA genes in normal and neoplastic cells. Cell Cycle 2007; 6: 1001-5.
-
(2007)
Cell Cycle
, vol.6
, pp. 1001-1005
-
-
Weber, B.1
Stresemann, C.2
Brueckner, B.3
-
79
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA etal. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999; 99: 247-57.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
-
80
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992; 69: 915-26.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
81
-
-
31944448123
-
p16INK4A and CDH13 hypermethylation in tumor and serum of non-small cell lung cancer patients
-
Ulivi P, Zoli W, Calistri D etal. p16INK4A and CDH13 hypermethylation in tumor and serum of non-small cell lung cancer patients. J Cell Physiol 2006; 206: 611-5.
-
(2006)
J Cell Physiol
, vol.206
, pp. 611-615
-
-
Ulivi, P.1
Zoli, W.2
Calistri, D.3
-
82
-
-
20144372911
-
Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer
-
Iliopoulos D, Guler G, Han SY etal. Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer. Oncogene 2005; 24: 1625-33.
-
(2005)
Oncogene
, vol.24
, pp. 1625-1633
-
-
Iliopoulos, D.1
Guler, G.2
Han, S.Y.3
-
83
-
-
33847748913
-
The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function
-
Brueckner B, Stresemann C, Kuner R etal. The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function. Cancer Res 2007; 67: 1419-23.
-
(2007)
Cancer Res
, vol.67
, pp. 1419-1423
-
-
Brueckner, B.1
Stresemann, C.2
Kuner, R.3
-
84
-
-
44449149903
-
Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression
-
Bueno MJ, Perez de Castro I, Gomez de Cedron M etal. Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression. Cancer Cell 2008; 13: 496-506.
-
(2008)
Cancer Cell
, vol.13
, pp. 496-506
-
-
Bueno, M.J.1
Perez de Castro, I.2
Gomez de Cedron, M.3
-
85
-
-
35748979703
-
Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein
-
Fazi F, Racanicchi S, Zardo G etal. Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein. Cancer Cell 2007; 12: 457-66.
-
(2007)
Cancer Cell
, vol.12
, pp. 457-466
-
-
Fazi, F.1
Racanicchi, S.2
Zardo, G.3
-
86
-
-
33847763576
-
Genetic unmasking of an epigenetically silenced microRNA in human cancer cells
-
Lujambio A, Ropero S, Ballestar E etal. Genetic unmasking of an epigenetically silenced microRNA in human cancer cells. Cancer Res 2007; 67: 1424-9.
-
(2007)
Cancer Res
, vol.67
, pp. 1424-1429
-
-
Lujambio, A.1
Ropero, S.2
Ballestar, E.3
-
87
-
-
70849087385
-
miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer
-
Gallardo E, Navarro A, Vinolas N etal. miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer. Carcinogenesis 2009; 30: 1903-9.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1903-1909
-
-
Gallardo, E.1
Navarro, A.2
Vinolas, N.3
-
88
-
-
77955755505
-
Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumors
-
Sempere LF, Preis M, Yezefski T etal. Fluorescence-based codetection with protein markers reveals distinct cellular compartments for altered MicroRNA expression in solid tumors. Clin Cancer Res 2010; 16: 4246-55.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4246-4255
-
-
Sempere, L.F.1
Preis, M.2
Yezefski, T.3
-
89
-
-
77952292883
-
Regulating A549 cells growth by ASO inhibiting miRNA expression
-
Wang PY, Li YJ, Zhang S etal. Regulating A549 cells growth by ASO inhibiting miRNA expression. Mol Cell Biochem 2010; 339: 163-71.
-
(2010)
Mol Cell Biochem
, vol.339
, pp. 163-171
-
-
Wang, P.Y.1
Li, Y.J.2
Zhang, S.3
-
90
-
-
77955022405
-
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
-
Wiggins JF, Ruffino L, Kelnar K etal. Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res 2010; 70: 5923-30.
-
(2010)
Cancer Res
, vol.70
, pp. 5923-5930
-
-
Wiggins, J.F.1
Ruffino, L.2
Kelnar, K.3
-
91
-
-
44649163918
-
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
-
Burk U, Schubert J, Wellner U etal. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008; 9: 582-9.
-
(2008)
EMBO Rep
, vol.9
, pp. 582-589
-
-
Burk, U.1
Schubert, J.2
Wellner, U.3
-
92
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Gregory PA, Bert AG, Paterson EL etal. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10: 593-601.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
-
93
-
-
47249091921
-
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
-
Korpal M, Lee ES, Hu G etal. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 2008; 283: 14910-4.
-
(2008)
J Biol Chem
, vol.283
, pp. 14910-14914
-
-
Korpal, M.1
Lee, E.S.2
Hu, G.3
-
94
-
-
41649091906
-
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
-
Park SM, Gaur AB, Lengyel E etal. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 2008; 22: 894-907.
-
(2008)
Genes Dev
, vol.22
, pp. 894-907
-
-
Park, S.M.1
Gaur, A.B.2
Lengyel, E.3
-
95
-
-
33747891190
-
Elevated mRNA levels of DNA methyltransferase-1 as an independent prognostic factor in primary nonsmall cell lung cancer
-
Kim H, Kwon YM, Kim JS etal. Elevated mRNA levels of DNA methyltransferase-1 as an independent prognostic factor in primary nonsmall cell lung cancer. Cancer 2006; 107: 1042-9.
-
(2006)
Cancer
, vol.107
, pp. 1042-1049
-
-
Kim, H.1
Kwon, Y.M.2
Kim, J.S.3
-
96
-
-
33846111256
-
Alteration of DNA methyltransferases contributes to 5′CpG methylation and poor prognosis in lung cancer
-
Lin RK, Hsu HS, Chang JW etal. Alteration of DNA methyltransferases contributes to 5′CpG methylation and poor prognosis in lung cancer. Lung Cancer 2007; 55: 205-13.
-
(2007)
Lung Cancer
, vol.55
, pp. 205-213
-
-
Lin, R.K.1
Hsu, H.S.2
Chang, J.W.3
-
97
-
-
33748373149
-
DNA methyltransferases messenger RNA expression and aberrant methylation of CpG islands in non-small-cell lung cancer: association and prognostic value
-
Vallbohmer D, Brabender J, Yang D etal. DNA methyltransferases messenger RNA expression and aberrant methylation of CpG islands in non-small-cell lung cancer: association and prognostic value. Clin Lung Cancer 2006; 8: 39-44.
-
(2006)
Clin Lung Cancer
, vol.8
, pp. 39-44
-
-
Vallbohmer, D.1
Brabender, J.2
Yang, D.3
-
98
-
-
73449113904
-
Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
-
Hervouet E, Vallette FM, Cartron PF. Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation. Epigenetics 2009; 4: 487-99.
-
(2009)
Epigenetics
, vol.4
, pp. 487-499
-
-
Hervouet, E.1
Vallette, F.M.2
Cartron, P.F.3
-
99
-
-
0036735345
-
A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer
-
Shen H, Wang L, Spitz MR etal. A novel polymorphism in human cytosine DNA-methyltransferase-3B promoter is associated with an increased risk of lung cancer. Cancer Res 2002; 62: 4992-5.
-
(2002)
Cancer Res
, vol.62
, pp. 4992-4995
-
-
Shen, H.1
Wang, L.2
Spitz, M.R.3
-
100
-
-
77955015091
-
Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer
-
Lin RK, Wu CY, Chang JW etal. Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer. Cancer Res 2010; 70: 5807-17.
-
(2010)
Cancer Res
, vol.70
, pp. 5807-5817
-
-
Lin, R.K.1
Wu, C.Y.2
Chang, J.W.3
-
101
-
-
67650588646
-
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
-
Garzon R, Liu S, Fabbri M etal. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 2009; 113: 6411-8.
-
(2009)
Blood
, vol.113
, pp. 6411-6418
-
-
Garzon, R.1
Liu, S.2
Fabbri, M.3
-
102
-
-
79952421239
-
Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma
-
Nguyen T, Kuo C, Nicholl MB etal. Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma. Epigenetics 2011; 6: 388-94.
-
(2011)
Epigenetics
, vol.6
, pp. 388-394
-
-
Nguyen, T.1
Kuo, C.2
Nicholl, M.B.3
-
103
-
-
34548480199
-
DNA methylation and histone modifications in patients with cancer potential prognostic and therapeutic targets
-
Sioud M (ed.). Humana Press Inc., Totowa, NJ
-
Herranz M, Esteller M. DNA methylation and histone modifications in patients with cancer potential prognostic and therapeutic targets. In: Sioud M (ed.). Target Discovery and Validation Reviews and Protocolsed. Vol. 2. Humana Press Inc., Totowa, NJ 2007; 25-62.
-
(2007)
Target Discovery and Validation Reviews and Protocolsed
, vol.2
, pp. 25-62
-
-
Herranz, M.1
Esteller, M.2
-
104
-
-
34248649731
-
The molecular mechanism of HDAC inhibitors in anticancer effects
-
Bi G, Jiang G. The molecular mechanism of HDAC inhibitors in anticancer effects. Cell Mol Immunol 2006; 3: 285-90.
-
(2006)
Cell Mol Immunol
, vol.3
, pp. 285-290
-
-
Bi, G.1
Jiang, G.2
-
105
-
-
39049093364
-
[Tumor-suppressing role of cellular senescence and chromatin structure]
-
Funayama R, Ishikawa F. [Tumor-suppressing role of cellular senescence and chromatin structure]. Nippon Ronen Igakkai Zasshi 2007; 44: 546-50.
-
(2007)
Nippon Ronen Igakkai Zasshi
, vol.44
, pp. 546-550
-
-
Funayama, R.1
Ishikawa, F.2
-
106
-
-
73749085370
-
Epigenetic factors in aging and longevity
-
Gravina S, Vijg J. Epigenetic factors in aging and longevity. Pflugers Arch 2010; 459: 247-58.
-
(2010)
Pflugers Arch
, vol.459
, pp. 247-258
-
-
Gravina, S.1
Vijg, J.2
-
107
-
-
33646153307
-
Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation
-
Munoz-Najar UM, Neurath KM, Vumbaca F etal. Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation. Oncogene 2006; 25: 2379-92.
-
(2006)
Oncogene
, vol.25
, pp. 2379-2392
-
-
Munoz-Najar, U.M.1
Neurath, K.M.2
Vumbaca, F.3
-
108
-
-
34249033131
-
Histone deacetylase inhibitors: molecular and biological activity as a premise to clinical application
-
Santini V, Gozzini A, Ferrari G. Histone deacetylase inhibitors: molecular and biological activity as a premise to clinical application. Curr Drug Metab 2007; 8: 383-93.
-
(2007)
Curr Drug Metab
, vol.8
, pp. 383-393
-
-
Santini, V.1
Gozzini, A.2
Ferrari, G.3
-
109
-
-
69249132204
-
Pathogenesis of lung cancer signalling pathways: roadmap for therapies
-
Brambilla E, Gazdar A. Pathogenesis of lung cancer signalling pathways: roadmap for therapies. Eur Respir J 2009; 33: 1485-97.
-
(2009)
Eur Respir J
, vol.33
, pp. 1485-1497
-
-
Brambilla, E.1
Gazdar, A.2
-
110
-
-
58149329023
-
Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer
-
Van Den Broeck A, Brambilla E, Moro-Sibilot D etal. Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer. Clin Cancer Res 2008; 14: 7237-45.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7237-7245
-
-
Van Den Broeck, A.1
Brambilla, E.2
Moro-Sibilot, D.3
-
111
-
-
32944462300
-
Rapid alteration of microRNA levels by histone deacetylase inhibition
-
Scott GK, Mattie MD, Berger CE etal. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res 2006; 66: 1277-81.
-
(2006)
Cancer Res
, vol.66
, pp. 1277-1281
-
-
Scott, G.K.1
Mattie, M.D.2
Berger, C.E.3
-
112
-
-
77956592888
-
microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia
-
Roccaro AM, Sacco A, Jia X etal. microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia. Blood 2010; 116: 1506-14.
-
(2010)
Blood
, vol.116
, pp. 1506-1514
-
-
Roccaro, A.M.1
Sacco, A.2
Jia, X.3
-
113
-
-
77957982588
-
microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity
-
Zhang J, Yang Y, Yang T etal. microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity. Br J Cancer 2010; 103: 1215-20.
-
(2010)
Br J Cancer
, vol.103
, pp. 1215-1220
-
-
Zhang, J.1
Yang, Y.2
Yang, T.3
-
114
-
-
33745813856
-
The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells
-
Tuddenham L, Wheeler G, Ntounia-Fousara S etal. The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells. FEBS Lett 2006; 580: 4214-7.
-
(2006)
FEBS Lett
, vol.580
, pp. 4214-4217
-
-
Tuddenham, L.1
Wheeler, G.2
Ntounia-Fousara, S.3
-
115
-
-
70450237022
-
Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells
-
Song B, Wang Y, Xi Y etal. Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. Oncogene 2009; 28: 4065-74.
-
(2009)
Oncogene
, vol.28
, pp. 4065-4074
-
-
Song, B.1
Wang, Y.2
Xi, Y.3
|