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Volumn 29, Issue 5-6, 2012, Pages 863-874

Angiotensin II induces angiogenic factors production partly via AT1/JAK2/STAT3/SOCS3 signaling pathway in MHCC97H cells

Author keywords

Angiogenesis; Angiotensin II; Hepatocellular carcinoma; Janus kinase 2; Suppressor of cytokine signaling 3

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOGENIC FACTOR; ANGIOPOIETIN RECEPTOR; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; JANUS KINASE 2; LOSARTAN; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; SMALL INTERFERING RNA; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; VASCULOTROPIN;

EID: 84861366277     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000171034     Document Type: Article
Times cited : (38)

References (53)
  • 1
    • 0141491273 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • DOI 10.1016/S0140-6736(03)14964-1
    • Llovet JM, Burroughs A, Bruix J: Hepatocellular carcinoma. Lancet 2003;362:1907-1917. (Pubitemid 37518510)
    • (2003) Lancet , vol.362 , Issue.9399 , pp. 1907-1917
    • Llovet, J.M.1    Burroughs, A.2    Bruix, J.3
  • 2
    • 0035281547 scopus 로고    scopus 로고
    • Risk factors for distant recurrence of hepatocellular carcinoma in the liver after complete coagulation by microwave or radiofrequency ablation
    • Izumi N, Asahina Y, Noguchi O, Uchihara M, Kanazawa N, Itakura J, Himeno Y, Miyake S, Sakai T, Enomoto N: Risk factors for distant recurrence of hepatocellular carcinoma in the liver after complete coagulation by microwave or radiofrequency ablation. Cancer 2001;91:949-956.
    • (2001) Cancer , vol.91 , pp. 949-956
    • Izumi, N.1    Asahina, Y.2    Noguchi, O.3    Uchihara, M.4    Kanazawa, N.5    Itakura, J.6    Himeno, Y.7    Miyake, S.8    Sakai, T.9    Enomoto, N.10
  • 4
    • 77950654038 scopus 로고    scopus 로고
    • Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth human hepatocellular carcinoma cells
    • Ke Z, Li HY, Su XL, Wang XY, Tian T, Li F, Ren GS: Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth human hepatocellular carcinoma cells. J Exp Clin Cancer Res 2010;29:31.
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 31
    • Ke, Z.1    Li, H.Y.2    Su, X.L.3    Wang, X.Y.4    Tian, T.5    Li, F.6    Ren, G.S.7
  • 5
    • 55549120187 scopus 로고    scopus 로고
    • SiRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo
    • Raskopf E, Vogt A, Sauerbruch T, Schmitz V: siRNA targeting VEGF inhibits hepatocellular carcinoma growth and tumor angiogenesis in vivo. J Hepatol 2008;49:977-984.
    • (2008) J Hepatol , vol.49 , pp. 977-984
    • Raskopf, E.1    Vogt, A.2    Sauerbruch, T.3    Schmitz, V.4
  • 6
    • 33748630200 scopus 로고    scopus 로고
    • Expression of angiopoietins, Tie2 and vascular endothelial growth factor in angiogenesis and progression of hepatocellular carcinoma
    • Zhang ZL, Liu ZS, Sun Q: Expression of angiopoietins, Tie2 and vascular endothelial growth factor in angiogenesis and progression of hepatocellular carcinoma. World J Gastroenterol 2006;12:4241-4245. (Pubitemid 44376912)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.26 , pp. 4241-4245
    • Zhang, Z.-L.1    Liu, Z.-S.2    Sun, Q.3
  • 10
    • 77956507930 scopus 로고    scopus 로고
    • Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway
    • Zhao Y, Chen X, Cai L, Yang Y, Sui G, Fu S: Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway. J Cell Physiol 2010;225:168-173.
    • (2010) J Cell Physiol , vol.225 , pp. 168-173
    • Zhao, Y.1    Chen, X.2    Cai, L.3    Yang, Y.4    Sui, G.5    Fu, S.6
  • 11
    • 23944434473 scopus 로고    scopus 로고
    • Angiotensin receptors: A new role in cancer?
    • DOI 10.1016/j.tem.2005.07.009, PII S1043276005001566
    • Deshayes F, Nahmias C: Angiotensin receptors: a new role in cancer? Trends Endocrinol Metab 2005;16:293-299. (Pubitemid 41206635)
    • (2005) Trends in Endocrinology and Metabolism , vol.16 , Issue.7 , pp. 293-299
    • Deshayes, F.1    Nahmias, C.2
  • 12
    • 77950637731 scopus 로고    scopus 로고
    • Change in the renin angiotensin system during the development of colorectal cancer liver metastases
    • Neo JH, Ager EI, Angus PW, Zhu J, Herath CB, Christophi C: Change in the renin angiotensin system during the development of colorectal cancer liver metastases. BMC Cancer 2010;10:134.
    • (2010) BMC Cancer , vol.10 , pp. 134
    • Neo, J.H.1    Ager, E.I.2    Angus, P.W.3    Zhu, J.4    Herath, C.B.5    Christophi, C.6
  • 16
    • 77649318669 scopus 로고    scopus 로고
    • RAAS inhibitors as therapeutic alternatives in the treatment of chronic liver diseases
    • Yoshiji H, Noguchi R, Fukui H: RAAS inhibitors as therapeutic alternatives in the treatment of chronic liver diseases. Nippon Rinsho 2009;67:799-806.
    • (2009) Nippon Rinsho , vol.67 , pp. 799-806
    • Yoshiji, H.1    Noguchi, R.2    Fukui, H.3
  • 17
    • 0035142665 scopus 로고    scopus 로고
    • Activation of STAT proteins and growth control
    • DOI 10.1002/1521-1878(200102)23:2<161::AID-BIES1023>3.0.CO;2-0
    • Bromberg JF: Activation of STAT proteins and growth control. Bioessays 2001;23:161-169. (Pubitemid 32116649)
    • (2001) BioEssays , vol.23 , Issue.2 , pp. 161-169
    • Bromberg, J.F.1
  • 18
    • 0037138370 scopus 로고    scopus 로고
    • Signaling through the JAK/STAT pathway, recent advances and future challenges
    • DOI 10.1016/S0378-1119(02)00398-0, PII S0378111902003980
    • Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW: Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 2002;285:1-24. (Pubitemid 34246317)
    • (2002) Gene , vol.285 , Issue.1-2 , pp. 1-24
    • Kisseleva, T.1    Bhattacharya, S.2    Braunstein, J.3    Schindler, C.W.4
  • 19
    • 1042302005 scopus 로고    scopus 로고
    • The stats of cancer - New molecular targets come of age
    • Yu H, Jove R: The STATs of cancer-new molecular target come of age. Nat Rev Cancer 2004;4:97-105. (Pubitemid 38198738)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 97-105
    • Yu, H.1    Jove, R.2
  • 20
    • 77954218447 scopus 로고    scopus 로고
    • Molecularly targeted therapy in hepatocellular carcinoma
    • Huynh H: Molecularly targeted therapy in hepatocellular carcinoma. Biochem Pharmacol 2010;80:550-560.
    • (2010) Biochem Pharmacol , vol.80 , pp. 550-560
    • Huynh, H.1
  • 21
    • 52949090018 scopus 로고    scopus 로고
    • SOCS regulation of the JAK/STAT signalling pathway
    • Croker BA, Kiu H, Nicholson SE: SOCS regulation of the JAK/STAT signalling pathway. Semin Cell Dev Biol 2008;19:414-422.
    • (2008) Semin Cell Dev Biol , vol.19 , pp. 414-422
    • Croker, B.A.1    Kiu, H.2    Nicholson, S.E.3
  • 22
    • 0344440953 scopus 로고    scopus 로고
    • Regulation of cytokine signaling by SOCS family molecules
    • DOI 10.1016/j.it.2003.10.008
    • Fujimoto M, Naka T: Regulation of cytokine signaling by SOCS family molecules. Trends Immunol 2003;24:659-666. (Pubitemid 37485916)
    • (2003) Trends in Immunology , vol.24 , Issue.12 , pp. 659-666
    • Fujimoto, M.1    Naka, T.2
  • 24
    • 40849113088 scopus 로고    scopus 로고
    • SOCS3 in liver regeneration and hepatocarcinoma
    • DOI 10.1124/mi.8.1.5
    • Elliott J: SOCS3 in liver regeneration and hepatocarcinoma. Mol Interv 2008;8:19-21. (Pubitemid 351398448)
    • (2008) Molecular Interventions , vol.8 , Issue.1 , pp. 19-21
    • Elliott, J.1
  • 25
    • 56449112678 scopus 로고    scopus 로고
    • Does the renin-angiotensin system participate in regulation of human vasculogenesis and angiogenesis?
    • Khakoo AY, Sidman RL, Pasqualini R, Arap W: Does the renin-angiotensin system participate in regulation of human vasculogenesis and angiogenesis? Cancer Res 2008;68:9112-9115.
    • (2008) Cancer Res , vol.68 , pp. 9112-9115
    • Khakoo, A.Y.1    Sidman, R.L.2    Pasqualini, R.3    Arap, W.4
  • 27
    • 14644410403 scopus 로고    scopus 로고
    • Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-κB: Implications for angioprevention and antiangiogenic therapy
    • DOI 10.1038/sj.onc.1208276
    • Singh RP, Dhanalakshmi S, Agarwal C, Agarwal R: Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NFkappaB: implications for angioprevention and antiangiogenic therapy. Oncogene 2005;24:1188-1202. (Pubitemid 40313920)
    • (2005) Oncogene , vol.24 , Issue.7 , pp. 1188-1202
    • Singh, R.P.1    Dhanalakshmi, S.2    Agarwal, C.3    Agarwal, R.4
  • 28
    • 66749097204 scopus 로고    scopus 로고
    • Angiotensin II induces inflammatory response partly via toll-like receptor 4-dependent signaling pathway in vascular smooth muscle cells
    • Ji YY, Liu JT, Wang ZD, Liu N: Angiotensin II induces inflammatory response partly via toll-like receptor 4-dependent signaling pathway in vascular smooth muscle cells. Cell Physiol Biochem 2009;23:265-276.
    • (2009) Cell Physiol Biochem , vol.23 , pp. 265-276
    • Ji, Y.Y.1    Liu, J.T.2    Wang, Z.D.3    Liu, N.4
  • 29
    • 33947370773 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) signaling in tumor progression
    • DOI 10.1016/j.critrevonc.2007.01.006, PII S1040842807000182
    • Roskoski R Jr: Vascular endothelial growth factor (VEGF) signaling in tumor progression. Crit Rev Oncol Hematol 2007;62:179-213. (Pubitemid 46679285)
    • (2007) Critical Reviews in Oncology/Hematology , vol.62 , Issue.3 , pp. 179-213
    • Roskoski Jr., R.1
  • 30
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • DOI 10.1016/S0092-8674(00)80108-7
    • Hanahan D, Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996;86:353-364. (Pubitemid 26272076)
    • (1996) Cell , vol.86 , Issue.3 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 32
    • 0036254553 scopus 로고    scopus 로고
    • Requisite role of VEGF receptors in angiogenesis of hepatocellular carcinoma: A comparison with angiopoietin/Tie pathway
    • Dhar DK, Naora H, Yamanoi A, Ono T, Kohno H, Otani H, Nagasue N: Requisite role of VEGF receptors in angiogenesis of hepatocellular carcinoma: a comparison with angiopoietin/Tie pathway. Anticancer Res 2002;22:379-386. (Pubitemid 34475326)
    • (2002) Anticancer Research , vol.22 , Issue.1 A , pp. 379-386
    • Dhar, D.K.1    Naora, H.2    Yamanoi, A.3    Ono, T.4    Kohno, H.5    Otani, H.6    Nagasue, N.7
  • 33
    • 0031690845 scopus 로고    scopus 로고
    • Increased expression of vascular endothelial growth factor is associated with tumor progression in hepatocellular carcinoma
    • DOI 10.1016/S0046-8177(98)90205-2
    • Torimura T, Sata M, Ueno T, Kin M, Tsuji R, Suzaku K, Hashimoto O, Sugawara H, Tanikawa K: Increased expression of vascular endothelial growth factor is associated with tumor progression in hepatocellular carcinoma. Hum Pathol 1998;29:986-991. (Pubitemid 28422048)
    • (1998) Human Pathology , vol.29 , Issue.9 , pp. 986-991
    • Torimura, T.1    Sata, M.2    Ueno, T.3    Kin, M.4    Tsuji, R.5    Suzaku, K.6    Hashimoto, O.7    Sugawara, H.8    Tanikawa, K.9
  • 34
    • 70350507211 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in the management of hepatocellular carcinoma: A review of literature
    • Kaseb AO, Hanbali A, Cotant M, Hassan MM, Wollner I, Philip PA: Vascular endothelial growth factor in the management of hepatocellular carcinoma: a review of literature. Cancer 2009;115:4895-4906.
    • (2009) Cancer , vol.115 , pp. 4895-4906
    • Kaseb, A.O.1    Hanbali, A.2    Cotant, M.3    Hassan, M.M.4    Wollner, I.5    Philip, P.A.6
  • 40
    • 33744802895 scopus 로고    scopus 로고
    • Angiopoietin-4 inhibits angiogenesis and reduces interstitial fluid pressure
    • DOI 10.1593/neo.06127
    • Olsen MW, Ley CD, Junker N, Hansen AJ, Lund EL, Kristjansen PE: Angiopoietin-4 inhibits angiogenesis and reduces interstitial Xuid pressure. Neoplasia 2006;8:364-372. (Pubitemid 43830743)
    • (2006) Neoplasia , vol.8 , Issue.5 , pp. 364-372
    • Olsen, M.W.B.1    Ley, C.D.2    Junker, N.3    Hansen, A.J.4    Lund, E.L.5    Kristjansen, P.E.G.6
  • 42
    • 64649084437 scopus 로고    scopus 로고
    • Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium
    • Yuan HT, Khankin EV, Karumanchi SA, Parikh SM: Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium. Mol Cell Biol 2009;29:2011-2022.
    • (2009) Mol Cell Biol , vol.29 , pp. 2011-2022
    • Yuan, H.T.1    Khankin, E.V.2    Karumanchi, S.A.3    Parikh, S.M.4
  • 43
    • 34248345563 scopus 로고    scopus 로고
    • The renin angiotensin system in the regulation of angiogenesis
    • DOI 10.2174/138161207780618858
    • Heffelfinger SC: The renin angiotensin system in the regulation of angiogenesis. Curr Pharm Des 2007;13:1215-1229. (Pubitemid 46739330)
    • (2007) Current Pharmaceutical Design , vol.13 , Issue.12 , pp. 1215-1229
    • Heffelfinger, S.C.1
  • 44
    • 79952189114 scopus 로고    scopus 로고
    • Immunohistochemical detection of phosphorylated JAK-2 and STAT-5 proteins and correlation with erythropoietin receptor (EpoR) expression status in human brain tumors
    • Kondyli M, Gatzounis G, Kyritsis A, Varakis J, Assimakopoulou M: Immunohistochemical detection of phosphorylated JAK-2 and STAT-5 proteins and correlation with erythropoietin receptor (EpoR) expression status in human brain tumors. J Neurooncol 2010;100:157-164.
    • (2010) J Neurooncol , vol.100 , pp. 157-164
    • Kondyli, M.1    Gatzounis, G.2    Kyritsis, A.3    Varakis, J.4    Assimakopoulou, M.5
  • 45
    • 0030046753 scopus 로고    scopus 로고
    • STATs: Signal transducers and activators of transcription
    • DOI 10.1016/S0092-8674(00)81277-5
    • Ihle JN: STATs: signal transducers and activators of transcription. Cell 1996;84:331-334. (Pubitemid 26058558)
    • (1996) Cell , vol.84 , Issue.3 , pp. 331-334
    • Ihle, J.N.1
  • 47
    • 34247600538 scopus 로고    scopus 로고
    • STAT3 as a central mediator of neoplastic cellular transformation
    • DOI 10.1016/j.canlet.2006.10.017, PII S0304383506005763
    • Frank DA: STAT3 as a central mediator of neoplastic cellular transformation. Cancer Lett 2007;251:199-210. (Pubitemid 46680370)
    • (2007) Cancer Letters , vol.251 , Issue.2 , pp. 199-210
    • Frank, D.A.1
  • 48
    • 40449129817 scopus 로고    scopus 로고
    • JAK kinases overexpression promotes in vitro cell transformation
    • DOI 10.1038/sj.onc.1210800, PII 1210800
    • Knoops L, Hornakova T, Royer Y, Constantinescu SN, Renauld JC: JAK kinases overexpression promotes in vitro cell transformation. Oncogene 2008;27:1511-1519. (Pubitemid 351347883)
    • (2008) Oncogene , vol.27 , Issue.11 , pp. 1511-1519
    • Knoops, L.1    Hornakova, T.2    Royer, Y.3    Constantinescu, S.N.4    Renauld, J.-C.5
  • 49
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, Jove R: Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 2002;8:945-954. (Pubitemid 35177340)
    • (2002) Clinical Cancer Research , vol.8 , Issue.4 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 51
    • 13844255555 scopus 로고    scopus 로고
    • Angiotensin type 1a receptor signaling-dependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor growth
    • DOI 10.1093/carcin/bgh324
    • Fujita M, Hayashi I, Yamashina S, Fukamizu A, Itoman M, Majima M: Angiotensin type 1a receptor signalingdependent induction of vascular endothelial growth factor in stroma is relevant to tumor-associated angiogenesis and tumor growth. Carcinogenesis 2005;26:271-279. (Pubitemid 40253497)
    • (2005) Carcinogenesis , vol.26 , Issue.2 , pp. 271-279
    • Fujita, M.1    Hayashi, I.2    Yamashina, S.3    Fukamizu, A.4    Itoman, M.5    Majima, M.6
  • 52
    • 71349083403 scopus 로고    scopus 로고
    • Angiotensin II activates JAK2/STAT3 pathway and induces interleukin-6 production in cultured rat brainstem astrocytes
    • Kandalam U, Clark MA: Angiotensin II activates JAK2/STAT3 pathway and induces interleukin-6 production in cultured rat brainstem astrocytes. Regul Pept 2010;159:110-116.
    • (2010) Regul Pept , vol.159 , pp. 110-116
    • Kandalam, U.1    Clark, M.A.2


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