-
1
-
-
79952040579
-
Prevalence and perceived health associated with insomnia based on DSM-IV-TR; international statistical classification of diseases and related health problems, tenth revision; and research diagnostic criteria/ international classification of sleep disorders, second edition criteria: Results from the america insomnia survey
-
Roth T, Coulouvrat C, Hajak G, et al. Prevalence and perceived health associated with insomnia based on DSM-IV-TR; International Statistical Classification of Diseases and Related Health Problems, Tenth Revision; and Research Diagnostic Criteria/ International Classification of Sleep Disorders, Second Edition criteria: results from the America Insomnia Survey. Biol Psychiatry 2011;69:592-600
-
(2011)
Biol. Psychiatry
, vol.69
, pp. 592-600
-
-
Roth, T.1
Coulouvrat, C.2
Hajak, G.3
-
2
-
-
79953667924
-
The association between insomnia severity and healthcare and productivity costs in a health plan sample
-
Sarsour K, Kalsekar A, Swindle R, et al. The association between insomnia severity and healthcare and productivity costs in a health plan sample. Sleep 2011;34:443-50
-
(2011)
Sleep
, vol.34
, pp. 443-450
-
-
Sarsour, K.1
Kalsekar, A.2
Swindle, R.3
-
3
-
-
0036526075
-
Epidemiology of insomnia: What we know and what we still need to learn
-
Ohayon MM. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Medicine Reviews 2002;6:97-111
-
(2002)
Sleep Med.icine Reviews
, vol.6
, pp. 97-111
-
-
Ohayon, M.M.1
-
4
-
-
0028034714
-
Sleep onset insomnia, sleep maintaining insomnia and insomnia with early morning awakening-temporal stability of subtypes in a longitudinal study on general practice attenders
-
Hohagen F, Kappler C, Schramm E, et al. Sleep onset insomnia, sleep maintaining insomnia and insomnia with early morning awakening-temporal stability of subtypes in a longitudinal study on general practice attenders. Sleep 1994;17:551-4
-
(1994)
Sleep
, vol.17
, pp. 551-554
-
-
Hohagen, F.1
Kappler, C.2
Schramm, E.3
-
5
-
-
33745779677
-
Defining insomnia: The role of quantitative criteria
-
Roth T, Drake C. Defining insomnia: the role of quantitative criteria. Sleep 2006;29:424-5
-
(2006)
Sleep
, vol.29
, pp. 424-425
-
-
Roth, T.1
Drake, C.2
-
6
-
-
33751548687
-
Sleep problems, comorbid mental disorders, and role functioning in the national comorbidity survey replication
-
Roth T, Jaeger S, Jin R, et al. Sleep problems, comorbid mental disorders, and role functioning in the national comorbidity survey replication. Biological Psychiatry 2006;60:1364-71
-
(2006)
Biological Psychiatry
, vol.60
, pp. 1364-1371
-
-
Roth, T.1
Jaeger, S.2
Jin, R.3
-
7
-
-
40949094337
-
A bidirectional relationship between anxiety and depression, and insomnia A prospective study in the general population
-
Jansson-Frojmark M, Lindblom K. A bidirectional relationship between anxiety and depression, and insomnia? A prospective study in the general population. Journal of Psychosomatic Research 2008;64:443-9
-
(2008)
Journal of Psychosomatic Research
, vol.64
, pp. 443-449
-
-
Jansson-Frojmark, M.1
Lindblom, K.2
-
8
-
-
62349100214
-
The natural history of insomnia: A population-based 3-year longitudinal study
-
Morin CM, Belanger L, LeBlanc M, et al. The natural history of insomnia: a population-based 3-year longitudinal study. Arch Intern Med 2009;169:447-53
-
(2009)
Arch. Intern. Med.
, vol.169
, pp. 447-453
-
-
Morin, C.M.1
Belanger, L.2
LeBlanc, M.3
-
9
-
-
34548487159
-
Insomnia: Definition, prevalence, etiology, and consequences
-
Roth T. Insomnia: definition, prevalence, etiology, and consequences. J Clin Sleep Med 2007;3:S7-10
-
(2007)
J. Clin. Sleep Med.
, vol.3
-
-
Roth, T.1
-
10
-
-
0030725377
-
How a general population perceives its sleep and how this relates to the complaint of insomnia
-
Ohayon MM, Caulet M, Guilleminault C. How a general population perceives its sleep and how this relates to the complaint of insomnia. Sleep 1997;20:715-23
-
(1997)
Sleep
, vol.20
, pp. 715-723
-
-
Ohayon, M.M.1
Caulet, M.2
Guilleminault, C.3
-
12
-
-
0036347861
-
Gender differences in insomnia - A study in the hong kong chinese population
-
Li RH, Wing YK, Ho SC, Fong SY. Gender differences in insomnia-a study in the Hong Kong Chinese population. J Psychosom Res 2002;53:601-9
-
(2002)
J. Psychosom. Res.
, vol.53
, pp. 601-609
-
-
Li, R.H.1
Wing, Y.K.2
Ho, S.C.3
Fong, S.Y.4
-
14
-
-
43749096378
-
Insomnia and depression
-
Taylor DJ. Insomnia and depression. Sleep 2008;31:447-8
-
(2008)
Sleep
, vol.31
, pp. 447-448
-
-
Taylor, D.J.1
-
15
-
-
43749096376
-
Prevalence, course, and comorbidity of insomnia and depression in young adults
-
Buysse DJ, Angst J, Gamma A, et al. Prevalence, course, and comorbidity of insomnia and depression in young adults. Sleep 2008;31:473-80
-
(2008)
Sleep
, vol.31
, pp. 473-480
-
-
Buysse, D.J.1
Angst, J.2
Gamma, A.3
-
16
-
-
43749117988
-
Is insomnia a perpetuating factor for late-life depression in the IMPACT cohort
-
Pigeon WR, Hegel M, Unutzer J, et al. Is insomnia a perpetuating factor for late-life depression in the IMPACT cohort? Sleep 2008;31:481-8
-
(2008)
Sleep
, vol.31
, pp. 481-488
-
-
Pigeon, W.R.1
Hegel, M.2
Unutzer, J.3
-
17
-
-
16644363477
-
Sleep and adolescent suicidal behavior
-
Liu X. Sleep and adolescent suicidal behavior. Sleep 2004;27:1351-8
-
(2004)
Sleep
, vol.27
, pp. 1351-358
-
-
Liu, X.1
-
18
-
-
80053525479
-
Insomnia as a predictor of depression: A meta-analytic evaluation of longitudinal epidemiological studies
-
Baglioni C, Battagliese G, Feige B, et al. Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies. Journal of Affective Disorders 2011;135:10-19
-
(2011)
Journal of Affective Disorders
, vol.135
, pp. 10-19
-
-
Baglioni, C.1
Battagliese, G.2
Feige, B.3
-
19
-
-
84873073633
-
-
Available from: [Accessed January 2012]
-
Available from: http://www. sleepfoundation.org/sites/default/files/ sleepinamericapoll/ SIAP-2011-Summary-of-Findings.pdf [Accessed January 2012] 2011
-
(2011)
-
-
-
20
-
-
0025768253
-
The beneficial and adverse effects of hypnotics
-
Balter MB, Uhlenhuth EH. The beneficial and adverse effects of hypnotics. J Clin Psychiatry 1991;52(Suppl):16-23
-
(1991)
J. Clin. Psychiatry
, vol.52
, Issue.SUPPL.
, pp. 16-23
-
-
Balter, M.B.1
Uhlenhuth, E.H.2
-
21
-
-
0033136218
-
Daytime consequences and correlates of insomnia in the United States: Results of the 1991 national sleep foundation survey II
-
Roth T, Ancoli-Israel S. Daytime consequences and correlates of insomnia in the United States: results of the 1991 National Sleep Foundation Survey. II. Sleep 1999;22(Suppl 2):S354-8
-
(1999)
Sleep
, vol.22
, Issue.SUPPL. 2
-
-
Roth, T.1
Ancoli-Israel, S.2
-
23
-
-
33947695769
-
The direct and indirect costs of untreated insomnia in adults in the United States
-
Ozminkowski RJ, Wang S, Walsh JK. The direct and indirect costs of untreated insomnia in adults in the United States. Sleep 2007;30:263-73
-
(2007)
Sleep
, vol.30
, pp. 263-273
-
-
Ozminkowski, R.J.1
Wang, S.2
Walsh, J.K.3
-
24
-
-
0033136181
-
The direct economic costs of insomnia in the United States for 1995
-
Walsh JK, Engelhardt CL. The direct economic costs of insomnia in the United States for 1995. Sleep 1999;22(Suppl 2):S386-93
-
(1999)
Sleep
, Issue.22 SUPPL. 2
-
-
Walsh, J.K.1
Engelhardt, C.L.2
-
25
-
-
0036120907
-
The relationship between insomnia and health-related quality of life in patients with chronic illness
-
Katz DA, McHorney CA. The relationship between insomnia and health-related quality of life in patients with chronic illness. J Fam Pract 2002;51:229-35
-
(2002)
J. Fam. Pract.
, vol.51
, pp. 229-235
-
-
Katz, D.A.1
McHorney, C.A.2
-
26
-
-
77956495216
-
-
American Psychiatry Association. Available from: Last accessed January 2012]
-
American Psychiatry Association. DSM-5 development Sleep-wake disorders. Available from: http://www. dsm5.org/proposedrevision/pages/ sleep-wakedisorders.aspx [Last accessed January 2012] 2010
-
(2010)
DSM-5 Development Sleep-Wake Disorders
-
-
-
27
-
-
72649097113
-
Hyperarousal and insomnia
-
Bonnet MH. Hyperarousal and insomnia. Sleep Med Rev 2010;14:33
-
(2010)
Sleep Med.. Rev.
, vol.14
, pp. 33
-
-
Bonnet, M.H.1
-
29
-
-
1542269240
-
A systematic review of non-pharmacological therapies for sleep problems in later life
-
Montgomery P, Dennis J. A systematic review of non-pharmacological therapies for sleep problems in later life. Sleep Med Rev 2004;8:47-62
-
(2004)
Sleep Med.. Rev.
, vol.8
, pp. 47-62
-
-
Montgomery, P.1
Dennis, J.2
-
30
-
-
0036357639
-
Comparative meta-analysis of pharmacotherapy and behavior therapy for persistent insomnia
-
Smith MT, Perlis ML, Park A, et al. Comparative meta-analysis of pharmacotherapy and behavior therapy for persistent insomnia. Am J Psychiatry 2002;159:5-11
-
(2002)
Am. J. Psychiatry
, vol.159
, pp. 5-11
-
-
Smith, M.T.1
Perlis, M.L.2
Park, A.3
-
31
-
-
0033577293
-
Behavioral and pharmacological therapies for late-life insomnia: A randomized controlled trial
-
Morin CM, Colecchi C, Stone J, et al. Behavioral and pharmacological therapies for late-life insomnia: a randomized controlled trial. JAMA 1999;281:991-9
-
(1999)
JAMA
, vol.281
, pp. 991-999
-
-
Morin, C.M.1
Colecchi, C.2
Stone, J.3
-
32
-
-
33751083841
-
Psychological and behavioral treatment of insomnia: Update of the recent evidence 1998 - 2004
-
Morin CM, Bootzin RR, Buysse DJ, et al. Psychological and behavioral treatment of insomnia: update of the recent evidence (1998 - 2004). Sleep 2006;29:1398-414
-
(2006)
Sleep
, vol.29
, pp. 1398-1414
-
-
Morin, C.M.1
Bootzin, R.R.2
Buysse, D.J.3
-
33
-
-
0037665273
-
Use of sleep hygiene in the treatment of insomnia
-
Stepanski EJ, Wyatt JK. Use of sleep hygiene in the treatment of insomnia. Sleep Med Rev 2003;7:215-25
-
(2003)
Sleep Med.. Rev.
, vol.7
, pp. 215-225
-
-
Stepanski, E.J.1
Wyatt, J.K.2
-
34
-
-
84861413350
-
National Institutes of Health state of the science conference statement on manifestations and management of chronic insomnia in adults
-
Health NIo. National Institutes of Health state of the science conference statement on manifestations and management of chronic insomnia in adults. Sleep 2005;28:59
-
(2005)
Sleep
, vol.28
, pp. 59
-
-
Health, N.1
-
35
-
-
55349132739
-
Clinical guideline for the evaluation and management of chronic insomnia in adults
-
Schutte-Rodin S, Broch L, Buysse D, et al. Clinical guideline for the evaluation and management of chronic insomnia in adults. J Clin Sleep Med 2008;4:487-504
-
(2008)
J. Clin. Sleep Med.
, vol.4
, pp. 487-504
-
-
Schutte-Rodin, S.1
Broch, L.2
Buysse, D.3
-
37
-
-
0035282713
-
Structure and function of GABA(C) receptors: A comparison of native versus recombinant receptors
-
Zhang D, Pan ZH, Awobuluyi M, Lipton SA. Structure and function of GABA(C) receptors: a comparison of native versus recombinant receptors. Trends Pharmacol Sci 2001;22:121-32
-
(2001)
Trends. Pharmacol. Sci.
, vol.22
, pp. 121-132
-
-
Zhang, D.1
Pan, Z.H.2
Awobuluyi, M.3
Lipton, S.A.4
-
38
-
-
54049137689
-
International union of pharmacology LXX Subtypes of gamma-aminobutyric acid(A) receptors: Classification on the basis of subunit composition, pharmacology, and function Update
-
Olsen RW, Sieghart W. International union of pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update. Pharmacol Rev 2008;60:243-60
-
(2008)
Pharmacol. Rev.
, vol.60
, pp. 243-260
-
-
Olsen, R.W.1
Sieghart, W.2
-
39
-
-
0042347457
-
Reducing GABA receptors
-
Burt DR. Reducing GABA receptors. Life Sci 2003;73:1741-58
-
(2003)
Life Sci.
, vol.73
, pp. 1741-1758
-
-
Burt, D.R.1
-
40
-
-
0035039871
-
Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux
-
Smith AJ, Alder L, Silk J, et al. Effect of alpha subunit on allosteric modulation of ion channel function in stably expressed human recombinant gamma-aminobutyric acid(A) receptors determined using (36)Cl ion flux. Mol Pharmacol 2001;59:1108-18
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1108-1118
-
-
Smith, A.J.1
Alder, L.2
Silk, J.3
-
41
-
-
0033592682
-
Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes
-
Rudolph U, Crestani F, Benke D, et al. Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes. Nature 1999;401:796-800
-
(1999)
Nature
, vol.401
, pp. 796-800
-
-
Rudolph, U.1
Crestani, F.2
Benke, D.3
-
42
-
-
1342344806
-
Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics
-
Rudolph U, Mohler H. Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics. Annu Rev Pharmacol Toxicol 2004;44:475-98
-
(2004)
Annu. Rev. Pharmacol. Toxicol.
, vol.44
, pp. 475-498
-
-
Rudolph, U.1
Mohler, H.2
-
44
-
-
0033626427
-
GABAB receptors: A new paradigm in G protein signaling
-
Couve A, Moss SJ, Pangalos MN. GABAB receptors: a new paradigm in G protein signaling. Mol Cell Neurosci 2000;16:296-312
-
(2000)
Mol. Cell Neurosci.
, vol.16
, pp. 296-312
-
-
Couve, A.1
Moss, S.J.2
Pangalos, M.N.3
-
45
-
-
0033582820
-
Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity
-
Ng GY, Clark J, Coulombe N, et al. Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity. J Biol Chem 1999;274:7607-10
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7607-7610
-
-
Ng, G.Y.1
Clark, J.2
Coulombe, N.3
-
46
-
-
0027082480
-
Gamma-aminobutyric acid a or c receptor gamma-aminobutyric acid rho 1 receptor RNA induces bicuculline-, barbiturate-, and benzodiazepine-insensitive gammaaminobutyric acid responses in Xenopus oocytes
-
Shimada S, Cutting G, Uhl GR. gamma-Aminobutyric acid A or C receptor? gamma-Aminobutyric acid rho 1 receptor RNA induces bicuculline-, barbiturate-, and benzodiazepine-insensitive gammaaminobutyric acid responses in Xenopus oocytes. Mol Pharmacol 1992;41:683-7
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 683-687
-
-
Shimada, S.1
Cutting, G.2
Uhl, G.R.3
-
47
-
-
0031469929
-
Benzodiazepines and zolpidem for chronic insomnia: A meta-analysis of treatment efficacy
-
Nowell PD, Mazumdar S, Buysse DJ, et al. Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy. JAMA 1997;278:2170-7
-
(1997)
JAMA
, vol.278
, pp. 2170-177
-
-
Nowell, P.D.1
Mazumdar, S.2
Buysse, D.J.3
-
48
-
-
0034711768
-
Meta-analysis of benzodiazepine use in the treatment of insomnia
-
Holbrook AM, Crowther R, Lotter A, et al. Meta-analysis of benzodiazepine use in the treatment of insomnia. CMAJ 2000;162:225-33
-
(2000)
CMAJ
, vol.162
, pp. 225-233
-
-
Holbrook, A.M.1
Crowther, R.2
Lotter, A.3
-
49
-
-
0026014236
-
A review of the safety profiles of benzodiazepine hypnotics
-
Roth T, Roehrs TA. A review of the safety profiles of benzodiazepine hypnotics. J Clin Psychiatry 1991;52(Suppl):38-41
-
(1991)
J. Clin. Psychiatry
, vol.52
, Issue.SUPPL.
, pp. 38-41
-
-
Roth, T.1
Roehrs, T.A.2
-
50
-
-
0027052696
-
Clinical distinctions between long-acting and short-acting benzodiazepines
-
Mendelson W. Clinical distinctions between long-acting and short-acting benzodiazepines. J Clin Psychiatry 1992;53(Suppl):2
-
(1992)
J. Clin. Psychiatry
, vol.53
, Issue.SUPPL.
, pp. 2
-
-
Mendelson, W.1
-
51
-
-
0026687682
-
Rebound insomnia in normals and patients with insomnia after abrupt and tapered discontinuation
-
Roehrs T, Merlotti L, Zorick F, Roth T. Rebound insomnia in normals and patients with insomnia after abrupt and tapered discontinuation. Psychopharmacology 1992;108:67-71
-
(1992)
Psychopharmacology
, vol.108
, pp. 67-71
-
-
Roehrs, T.1
Merlotti, L.2
Zorick, F.3
Roth, T.4
-
52
-
-
0023190754
-
Effect of gradual withdrawal on the rebound sleep disorder after discontinuation of triazolam
-
Greenblatt DJ, Harmatz JS, Zinny MA, Shader RI. Effect of gradual withdrawal on the rebound sleep disorder after discontinuation of triazolam. N Engl J Med 1987;317:722-8
-
(1987)
N. Engl. J. Med.
, vol.317
, pp. 722-728
-
-
Greenblatt, D.J.1
Harmatz, J.S.2
Zinny, M.A.3
Shader, R.I.4
-
54
-
-
0036107859
-
Long-term benzodiazepine use and cognitive decline in the elderly: The epidemiology of vascular aging study
-
Paterniti S, Dufouil C, Alperovitch A. Long-term benzodiazepine use and cognitive decline in the elderly: the Epidemiology of Vascular Aging Study. J Clin Psychopharmacol 2002;22:285-93
-
(2002)
J. Clin. Psychopharmacol.
, vol.22
, pp. 285-293
-
-
Paterniti, S.1
Dufouil, C.2
Alperovitch, A.3
-
55
-
-
23444461628
-
Insomnia and hypnotic use, recorded in the minimum data set, as predictors of falls and hip fractures in michigan nursing homes
-
Avidan AY, Fries BE, James ML, et al. Insomnia and hypnotic use, recorded in the minimum data set, as predictors of falls and hip fractures in michigan nursing homes. J Am Geriatr Soc 2005;53:955-62
-
(2005)
J. Am. Geriatr. Soc.
, vol.53
, pp. 955-962
-
-
Avidan, A.Y.1
Fries, B.E.2
James, M.L.3
-
56
-
-
0141892625
-
Medication use and falls in community-dwelling older persons
-
Kelly KD, Pickett W, Yiannakoulias N, et al. Medication use and falls in community-dwelling older persons. Age Ageing 2003;32:503-9
-
(2003)
Age Ageing
, vol.32
, pp. 503-509
-
-
Kelly, K.D.1
Pickett, W.2
Yiannakoulias, N.3
-
57
-
-
0024793608
-
Benzodiazepines of long and short elimination half-life and the risk of hip fracture
-
Ray WA, Griffin MR, Downey W. Benzodiazepines of long and short elimination half-life and the risk of hip fracture. JAMA 1989;262:3303-7
-
(1989)
JAMA
, vol.262
, pp. 3303-307
-
-
Ray, W.A.1
Griffin, M.R.2
Downey, W.3
-
58
-
-
84861359544
-
-
Ambien [package insert].New York NY:
-
Ambien [package insert]. Sanofi- Synthelabo, Inc.; New York, NY: 2004
-
(2004)
Sanofi-Synthelabo Inc
-
-
-
59
-
-
14944350787
-
Sleep terrors/ sleepwalking-not REM behavior disorder
-
Pressman MR, Mahowald MW, Schenck CH. Sleep terrors/ sleepwalking-not REM behavior disorder. Sleep 2005;28:278-9
-
(2005)
Sleep
, vol.28
, pp. 278-279
-
-
Pressman, M.R.1
Mahowald, M.W.2
Schenck, C.H.3
-
60
-
-
84873062375
-
-
Available from: Last accessed January 2012]
-
Micromedex 2.0. Available from: http://www.thomsonhc.com/micromedex2/ librarian [Last accessed January 2012] 2012
-
(2012)
Micromedex 20
-
-
-
61
-
-
33750720598
-
Dynamics and kinetics of a modified-release formulation of zolpidem: Comparison with immediate-release standard zolpidem and placebo
-
Greenblatt DJ, Legangneux E, Harmatz JS, et al. Dynamics and kinetics of a modified-release formulation of zolpidem: comparison with immediate-release standard zolpidem and placebo. J Clin Pharmacol 2006;46:1469-80
-
(2006)
J. Clin. Pharmacol.
, vol.46
, pp. 1469-1480
-
-
Greenblatt, D.J.1
Legangneux, E.2
Harmatz, J.S.3
-
63
-
-
0028360224
-
A multicenter, placebo-controlled study evaluating zolpidem in the treatment of chronic insomnia
-
Scharf MB, Roth T, Vogel GW, Walsh JK. A multicenter, placebo-controlled study evaluating zolpidem in the treatment of chronic insomnia. J Clin Psychiatry 1994;55:192-9
-
(1994)
J. Clin. Psychiatry
, vol.55
, pp. 192-199
-
-
Scharf, M.B.1
Roth, T.2
Vogel, G.W.3
Walsh, J.K.4
-
64
-
-
79851483617
-
Twelve months of nightly zolpidem does not lead to dose escalation: A prospective placebo-controlled study
-
Roehrs TA, Randall S, Harris E, et al. Twelve months of nightly zolpidem does not lead to dose escalation: a prospective placebo-controlled study. Sleep 2011;34:207-12
-
(2011)
Sleep
, vol.34
, pp. 207-212
-
-
Roehrs, T.A.1
Randall, S.2
Harris, E.3
-
65
-
-
37549026159
-
Long-term efficacy and safety of zolpidem extended-release 12.5 mg, administered 3 to 7 nights per week for 24 weeks, in patients with chronic primary insomnia: A 6-month, randomized, double-blind, placebo-controlled, parallel-group, multicenter study
-
Krystal AD, Erman M, Zammit GK, et al. Long-term efficacy and safety of zolpidem extended-release 12.5 mg, administered 3 to 7 nights per week for 24 weeks, in patients with chronic primary insomnia: a 6-month, randomized, double-blind, placebo-controlled, parallel-group, multicenter study. Sleep 2008;31:79-90
-
(2008)
Sleep
, vol.31
, pp. 79-90
-
-
Krystal, A.D.1
Erman, M.2
Zammit, G.K.3
-
66
-
-
54349128723
-
Zolpidem extended-release 12.5 mg associated with improvements in work performance in a 6-month randomized, placebo-controlled trial
-
Erman M, Guiraud A, Joish VN, Lerner D. Zolpidem extended-release 12.5 mg associated with improvements in work performance in a 6-month randomized, placebo-controlled trial. Sleep 2008;31:1371-8
-
(2008)
Sleep
, vol.31
, pp. 1371-378
-
-
Erman, M.1
Guiraud, A.2
Joish, V.N.3
Lerner, D.4
-
67
-
-
84861416020
-
-
Zolpimist [package insert].Richmond VA:
-
Zolpimist [package insert]. ECR Pharmaceuticals; Richmond, VA: 2010
-
(2010)
ECR Pharmaceuticals
-
-
-
68
-
-
84861354351
-
-
Intermezzo [package insert]. Inc.Pt. Richmond CA:
-
Intermezzo [package insert]. Transcept Pharmaceuticals, Inc.; Pt. Richmond, CA: 2011
-
(2011)
Transcept Pharmaceuticals
-
-
-
69
-
-
0034011740
-
Zolpidem: An update of its pharmacology, therapeutic efficacy and tolerability in the treatment of insomnia
-
Holm KJ, Goa KL. Zolpidem: an update of its pharmacology, therapeutic efficacy and tolerability in the treatment of insomnia. Drugs 2000;59:865-89
-
(2000)
Drugs
, vol.59
, pp. 865-889
-
-
Holm, K.J.1
Goa, K.L.2
-
70
-
-
0344631569
-
Sleep latency is shortened during 4 weeks of treatment with zaleplon, a novel nonbenzodiazepine hypnotic zaleplon clinical study group
-
Elie R, Ruther E, Farr I, et al. Sleep latency is shortened during 4 weeks of treatment with zaleplon, a novel nonbenzodiazepine hypnotic. Zaleplon Clinical Study Group. J Clin Psychiatry 1999;60:536-44
-
(1999)
J. Clin. Psychiatry
, vol.60
, pp. 536-544
-
-
Elie, R.1
Ruther, E.2
Farr, I.3
-
71
-
-
0028272986
-
Sleepwalking associated with zolpidem
-
Mendelson WB. Sleepwalking associated with zolpidem. J Clin Psychopharmacol 1994;14:150
-
(1994)
J. Clin. Psychopharmacol.
, vol.14
, pp. 150
-
-
Mendelson, W.B.1
-
72
-
-
0029797245
-
Amnesia possibly associated with zolpidem administration
-
Canaday BR. Amnesia possibly associated with zolpidem administration. Pharmacotherapy 1996;16:687-9
-
(1996)
Pharmacotherapy
, vol.16
, pp. 687-689
-
-
Canaday, B.R.1
-
74
-
-
0036053514
-
Amnestic sleep-related eating disorder associated with zolpidem
-
Morgenthaler TI, Silber MH. Amnestic sleep-related eating disorder associated with zolpidem. Sleep Med 2002;3:323-7
-
(2002)
Sleep Med..
, vol.3
, pp. 323-327
-
-
Morgenthaler, T.I.1
Silber, M.H.2
-
77
-
-
67349208203
-
Sublingual zolpidem is more effective than oral zolpidem in initiating early onset of sleep in the post-nap model of transient insomnia: A polysomnographic study
-
Staner L, Eriksson M, Cornette F, et al. Sublingual zolpidem is more effective than oral zolpidem in initiating early onset of sleep in the post-nap model of transient insomnia: a polysomnographic study. Sleep Med 2009;10:616-20
-
(2009)
Sleep Med..
, vol.10
, pp. 616-620
-
-
Staner, L.1
Eriksson, M.2
Cornette, F.3
-
78
-
-
77952478448
-
Sublingual zolpidem in early onset of sleep compared to oral zolpidem: Polysomnographic study in patients with primary insomnia
-
Staner C, Joly F, Jacquot N, et al. Sublingual zolpidem in early onset of sleep compared to oral zolpidem: polysomnographic study in patients with primary insomnia. Curr Med Res Opin 2010;26:1423-31
-
(2010)
Curr. Med. Res. Opin.
, vol.26
, pp. 1423-1431
-
-
Staner, C.1
Joly, F.2
Jacquot, N.3
-
79
-
-
51349086765
-
Low-dose sublingual zolpidem tartrate is associated with dose-related improvement in sleep onset and duration in insomnia characterized by middle-of-the - Night (MOTN) awakenings
-
Roth T, Hull SG, Lankford DA, et al. Low-dose sublingual zolpidem tartrate is associated with dose-related improvement in sleep onset and duration in insomnia characterized by middle-of-the-night (MOTN) awakenings. Sleep 2008;31:1277-84
-
(2008)
Sleep
, vol.31
, pp. 1277-1284
-
-
Roth, T.1
Hull, S.G.2
Lankford, D.A.3
-
80
-
-
84861359545
-
-
Sonata [package insert]. PA:
-
Sonata [package insert]. Wyeth; Philadelphia, PA: 2004
-
(2004)
-
-
Wyeth1
Philadelphia2
-
81
-
-
0033386952
-
Zaleplon displays selectivity to recombinant GABA-A receptors different from zolpidem, zopiclone and benzodiazepines
-
Damgen K, Luddens H. Zaleplon displays selectivity to recombinant GABA-A receptors different from zolpidem, zopiclone and benzodiazepines. Neurosci Res Commun 1999;25:10
-
(1999)
Neurosci. Res. Commun.
, vol.25
, pp. 10
-
-
Damgen, K.1
Luddens, H.2
-
82
-
-
0037072577
-
Comparison of the effects of zaleplon, zolpidem, and triazolam at various GABA(A) receptor subtypes
-
Sanna E, Busonero F, Talani G, et al. Comparison of the effects of zaleplon, zolpidem, and triazolam at various GABA(A) receptor subtypes. Eur J Pharmacol 2002;451:103-10
-
(2002)
Eur. J. Pharmacol.
, vol.451
, pp. 103-110
-
-
Sanna, E.1
Busonero, F.2
Talani, G.3
-
83
-
-
0033974316
-
Lack of residual sedation following middle-of-the - Night zaleplon administration in sleep maintenance insomnia
-
Walsh JK, Pollak CP, Scharf MB, et al. Lack of residual sedation following middle-of-the-night zaleplon administration in sleep maintenance insomnia. Clin Neuropharmacol 2000;23:17-21
-
(2000)
Clin. Neuropharmacol.
, vol.23
, pp. 17-21
-
-
Walsh, J.K.1
Pollak, C.P.2
Scharf, M.B.3
-
84
-
-
33751118748
-
Sleep and residual sedation after administration of zaleplon, zolpidem, and placebo during experimental middle-ofthe- night awakening
-
Zammit GK, Corser B, Doghramji K, et al. Sleep and residual sedation after administration of zaleplon, zolpidem, and placebo during experimental middle-ofthe- night awakening. J Clin Sleep Med 2006;2:417-23
-
(2006)
J. Clin. Sleep Med.
, vol.2
, pp. 417-423
-
-
Zammit, G.K.1
Corser, B.2
Doghramji, K.3
-
85
-
-
79952835153
-
A double-blind, randomized, comparative study to evaluate the efficacy and safety of zaleplon versus zolpidem in shortening sleep latency in primary insomnia
-
Huang YS, Hsu SC, Liu SI, Chen CK. A double-blind, randomized, comparative study to evaluate the efficacy and safety of zaleplon versus zolpidem in shortening sleep latency in primary insomnia. Chang Gung Med J 2011;34:50-6
-
(2011)
Chang. Gung. Med. J.
, vol.34
, pp. 50-6
-
-
Huang, Y.S.1
Hsu, S.C.2
Liu, S.I.3
Chen, C.K.4
-
86
-
-
0000248586
-
Zaleplon, a novel nonbenzodiazepine hypnotic, effectively treats insomnia in elderly patients without causing rebound effects
-
Ancoli-Israel S, Walsh JK, Mangano RM, Fujimori M. Zaleplon, a novel nonbenzodiazepine hypnotic, effectively treats insomnia in elderly patients without causing rebound effects. Prim Care Companion J Clin Psychiatry 1999;1:114-20
-
(1999)
Prim. Care Companion. J. Clin. Psychiatry
, vol.1
, pp. 114-120
-
-
Ancoli-Israel, S.1
Walsh, J.K.2
Mangano, R.M.3
Fujimori, M.4
-
87
-
-
0030910577
-
Minimal rebound insomnia after treatment with 10-mg zolpidem
-
Ware JC, Walsh JK, Scharf MB, et al. Minimal rebound insomnia after treatment with 10-mg zolpidem. Clin Neuropharmacol 1997;20:116-25
-
(1997)
Clin. Neuropharmacol.
, vol.20
, pp. 116-125
-
-
Ware, J.C.1
Walsh, J.K.2
Scharf, M.B.3
-
88
-
-
84858827460
-
Twelve months of nightly zolpidem does not lead to rebound insomnia or withdrawal symptoms: A prospective placebo-controlled study
-
Epub ahead of print]
-
Roehrs TA, Randall S, Harris E, et al. Twelve months of nightly zolpidem does not lead to rebound insomnia or withdrawal symptoms: a prospective placebo-controlled study. J Psychopharmacol 2011. [Epub ahead of print]
-
(2011)
J. Psychopharmacol.
-
-
Roehrs, T.A.1
Randall, S.2
Harris, E.3
-
89
-
-
84861395317
-
-
Lunesta [package insert]. MA:
-
Lunesta [package insert]. Sepracor; Marlborough, MA: 2005
-
(2005)
Sepracor; Marlborough
-
-
-
90
-
-
1842463058
-
Sustained efficacy of eszopiclone over 6 months of nightly treatment: Results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia
-
Krystal AD, Walsh JK, Laska E, et al. Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia. Sleep 2003;26:793-9
-
(2003)
Sleep
, vol.26
, pp. 793-799
-
-
Krystal, A.D.1
Walsh, J.K.2
Laska, E.3
-
91
-
-
13144294025
-
Efficacy and safety of eszopiclone across 6-weeks of treatment for primary insomnia
-
Zammit GK, McNabb LJ, Caron J, et al. Efficacy and safety of eszopiclone across 6-weeks of treatment for primary insomnia. Curr Med Res Opin 2004;20:1979-91
-
(2004)
Curr. Med. Res. Opin.
, vol.20
, pp. 1979-1991
-
-
Zammit, G.K.1
McNabb, L.J.2
Caron, J.3
-
92
-
-
34547677719
-
Nightly treatment of primary insomnia with eszopiclone for six months: Effect on sleep, quality of life, and work limitations
-
Walsh JK, Krystal AD, Amato DA, et al. Nightly treatment of primary insomnia with eszopiclone for six months: effect on sleep, quality of life, and work limitations. Sleep 2007;30:959-68
-
(2007)
Sleep
, vol.30
, pp. 959-968
-
-
Walsh, J.K.1
Krystal, A.D.2
Amato, D.A.3
-
93
-
-
20444417371
-
A 2-week efficacy and safety study of eszopiclone in elderly patients with primary insomnia
-
Scharf M, Erman M, Rosenberg R, et al. A 2-week efficacy and safety study of eszopiclone in elderly patients with primary insomnia. Sleep 2005;28:720-7
-
(2005)
Sleep
, vol.28
, pp. 720-727
-
-
Scharf, M.1
Erman, M.2
Rosenberg, R.3
-
94
-
-
33749005689
-
A polysomnography study of eszopiclone in elderly patients withinsomnia
-
McCall WV, Erman M, Krystal AD, et al. A polysomnography study of eszopiclone in elderly patients withinsomnia. Curr Med Res Opin 2006;22:1633-42
-
(2006)
Curr. Med. Res. Opin.
, vol.22
, pp. 1633-1642
-
-
McCall, W.V.1
Erman, M.2
Krystal, A.D.3
-
95
-
-
33845406163
-
Eszopiclone in patients with insomnia during perimenopause and early postmenopause: A randomized controlled trial
-
Soares CN, Joffe H, Rubens R, et al. Eszopiclone in patients with insomnia during perimenopause and early postmenopause: a randomized controlled trial. Obstet Gynecol 2006;108:1402-10
-
(2006)
Obstet. Gynecol.
, vol.108
, pp. 1402-1410
-
-
Soares, C.N.1
Joffe, H.2
Rubens, R.3
-
96
-
-
33744905209
-
Eszopiclone co-administered with fluoxetine in patients with insomnia coexisting with major depressive disorder
-
Fava M, McCall WV, Krystal A, et al. Eszopiclone co-administered with fluoxetine in patients with insomnia coexisting with major depressive disorder. Biol Psychiatry 2006;59:1052-60
-
(2006)
Biol. Psychiatry
, vol.59
, pp. 1052-1060
-
-
Fava, M.1
McCall, W.V.2
Krystal, A.3
-
97
-
-
43149106481
-
Eszopiclone coadministered with escitalopram in patients with insomnia and comorbid generalized anxiety disorder
-
Pollack M, Kinrys G, Krystal A, et al. Eszopiclone coadministered with escitalopram in patients with insomnia and comorbid generalized anxiety disorder. Arch Gen Psychiatry 2008;65:551-62
-
(2008)
Arch. Gen. Psychiatry
, vol.65
, pp. 551-562
-
-
Pollack, M.1
Kinrys, G.2
Krystal, A.3
-
98
-
-
74749107685
-
Eszopiclone improves insomnia and depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: A randomized, double-blinded, placebo-controlled crossover trial
-
Joffe H, Petrillo L, Viguera A, et al. Eszopiclone improves insomnia and depressive and anxious symptoms in perimenopausal and postmenopausal women with hot flashes: a randomized, double-blinded, placebo-controlled crossover trial. Am J Obstet Gynecol 2010;202:171; e171-171 e111
-
(2010)
Am. J. Obstet. Gynecol.
, vol.202
, Issue.171
-
-
Joffe, H.1
Petrillo, L.2
Viguera, A.3
-
99
-
-
79960725559
-
Improved insomnia symptoms and sleep-related next-day functioning in patients with comorbid major depressive disorder and insomnia following concomitant zolpidem extended-release 12.5 mg and escitalopram treatment: A randomized controlled trial
-
Fava M, Asnis GM, Shrivastava RK, et al. Improved insomnia symptoms and sleep-related next-day functioning in patients with comorbid major depressive disorder and insomnia following concomitant zolpidem extended-release 12.5 mg and escitalopram treatment: a randomized controlled trial. J Clin Psychiatry 2011;72:914-28
-
(2011)
J. Clin. Psychiatry
, vol.72
, pp. 914-928
-
-
Fava, M.1
Asnis, G.M.2
Shrivastava, R.K.3
-
100
-
-
79960728972
-
Eszopiclone for the treatment of posttraumatic stress disorder and associated insomnia: A randomized, double-blind, placebo-controlled trial
-
Pollack MH, Hoge EA, Worthington JJ, et al. Eszopiclone for the treatment of posttraumatic stress disorder and associated insomnia: a randomized, double-blind, placebo-controlled trial. J Clin Psychiatry 2011;72:892-7
-
(2011)
J. Clin. Psychiatry
, vol.72
, pp. 892-897
-
-
Pollack, M.H.1
Hoge, E.A.2
Worthington, J.J.3
-
101
-
-
79955510041
-
A post hoc analysis of the effect of nightly administration of eszopiclone and a selective serotonin reuptake inhibitor in patients with insomnia and anxious depression
-
Fava M, Schaefer K, Huang H, et al. A post hoc analysis of the effect of nightly administration of eszopiclone and a selective serotonin reuptake inhibitor in patients with insomnia and anxious depression. J Clin Psychiatry 2011;72:473-9
-
(2011)
J. Clin. Psychiatry
, vol.72
, pp. 473-479
-
-
Fava, M.1
Schaefer, K.2
Huang, H.3
-
102
-
-
27944440927
-
An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia
-
Roth T, Walsh JK, Krystal A, et al. An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia. Sleep Med 2005;6:487-95
-
(2005)
Sleep Med..
, vol.6
, pp. 487-495
-
-
Roth, T.1
Walsh, J.K.2
Krystal, A.3
-
103
-
-
79955597670
-
Are hypnotic benzodiazepine receptor agonists teratogenic in humans
-
Wikner BN, Kallen B. Are hypnotic benzodiazepine receptor agonists teratogenic in humans? J Clin Psychopharmacol 2011;31:356-9
-
(2011)
J. Clin. Psychopharmacol.
, vol.31
, pp. 356-359
-
-
Wikner, B.N.1
Kallen, B.2
-
104
-
-
67549122376
-
A compendium of placebo-controlled trials of the risks/ benefits of pharmacological treatments for insomnia: The empirical basis for US clinical practice
-
Krystal AD. A compendium of placebo-controlled trials of the risks/ benefits of pharmacological treatments for insomnia: the empirical basis for U.S. clinical practice. Sleep Med Rev 2009;13:265-74
-
(2009)
Sleep Med.. Rev.
, vol.13
, pp. 265-274
-
-
Krystal, A.D.1
-
105
-
-
12244286055
-
Ramelteon (TAK-375) accelerates reentrainment of circadian rhythm after a phase advance of the light-dark cycle in rats
-
Hirai K, Kita M, Ohta H, et al. Ramelteon (TAK-375) accelerates reentrainment of circadian rhythm after a phase advance of the light-dark cycle in rats. J Biol Rhythms 2005;20:27-37
-
(2005)
J. Biol. Rhythms.
, vol.20
, pp. 27-37
-
-
Hirai, K.1
Kita, M.2
Ohta, H.3
-
106
-
-
12244294179
-
The sleep-promoting action of ramelteon (TAK-375) in freely moving cats
-
Miyamoto M, Nishikawa H, Doken Y, et al. The sleep-promoting action of ramelteon (TAK-375) in freely moving cats. Sleep 2004;27:1319-25
-
(2004)
Sleep
, vol.27
, pp. 1319-1325
-
-
Miyamoto, M.1
Nishikawa, H.2
Doken, Y.3
-
107
-
-
0031886418
-
The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: Assessment in a clinical trial of melatonin replacement
-
Hughes RJ, Sack RL, Lewy AJ. The role of melatonin and circadian phase in age-related sleep-maintenance insomnia: assessment in a clinical trial of melatonin replacement. Sleep 1998;21:52-68
-
(1998)
Sleep
, vol.21
, pp. 52-68
-
-
Hughes, R.J.1
Sack, R.L.2
Lewy, A.J.3
-
108
-
-
0029090156
-
Melatonin replacement therapy of elderly insomniacs
-
Haimov I, Lavie P, Laudon M, et al. Melatonin replacement therapy of elderly insomniacs. Sleep 1995;18:598-603
-
(1995)
Sleep
, vol.18
, pp. 598-603
-
-
Haimov, I.1
Lavie, P.2
Laudon, M.3
-
109
-
-
0025878649
-
The effects of exogenous melatonin on the total sleep time and daytime alertness of chronic insomniacs: A preliminary study
-
MacFarlane JG, Cleghorn JM, Brown GM, Streiner DL. The effects of exogenous melatonin on the total sleep time and daytime alertness of chronic insomniacs: a preliminary study. Biol Psychiatry 1991;30:371-6
-
(1991)
Biol. Psychiatry
, vol.30
, pp. 371-376
-
-
MacFarlane, J.G.1
Cleghorn, J.M.2
Brown, G.M.3
Streiner, D.L.4
-
110
-
-
0037831118
-
Treatment of primary insomnia with melatonin: A double-blind, placebo-controlled, cross-over study
-
Montes LGA, Ontiveros Uribe MP, Cortes Sotres J. Treatment of primary insomnia with melatonin: a double-blind, placebo-controlled, cross-over study. J Psychiatry Neurosci 2003;28:6
-
(2003)
J. Psychiatry Neurosci.
, vol.28
, pp. 6
-
-
Montes, L.G.A.1
Ontiveros Uribe, M.P.2
Cortes Sotres, J.3
-
112
-
-
0346727185
-
Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy
-
Leger D, Laudon M, Zisapel N. Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy. Am J Med 2004;116:91-5
-
(2004)
Am. J. Med.
, vol.116
, pp. 91-95
-
-
Leger, D.1
Laudon, M.2
Zisapel, N.3
-
113
-
-
0028105342
-
Sleep disorders and melatonin rhythms in elderly people
-
Haimov I, Laudon M, Zisapel N, et al. Sleep disorders and melatonin rhythms in elderly people. BMJ 1994;309:167
-
(1994)
BMJ
, vol.309
, pp. 167
-
-
Haimov, I.1
Laudon, M.2
Zisapel, N.3
-
114
-
-
0034642063
-
Entrainment of free-running circadian rhythms by melatonin in blind people
-
Sack RL, Brandes RW, Kendall AR, Lewy AJ. Entrainment of free-running circadian rhythms by melatonin in blind people. N Engl J Med 2000;343:1070-7
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1070-077
-
-
Sack, R.L.1
Brandes, R.W.2
Kendall, A.R.3
Lewy, A.J.4
-
115
-
-
70449704975
-
New approaches in the management of insomnia: Weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists
-
Hardeland R. New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists. Neuropsychiatr Dis Treat 2009;5:341-54
-
(2009)
Neuropsychiatr. Dis. Treat.
, vol.5
, pp. 341-354
-
-
Hardeland, R.1
-
116
-
-
78651399199
-
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: A double-blind, placebo-controlled clinical trial
-
Rondanelli M, Opizzi A, Monteferrario F, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc 2011;59:82-90
-
(2011)
J. Am. Geriatr. Soc.
, vol.59
, pp. 82-90
-
-
Rondanelli, M.1
Opizzi, A.2
Monteferrario, F.3
-
117
-
-
84861354363
-
-
Rozerem [package insert]. Lincolnshire Ill:
-
Rozerem [package insert]. Takeda Laboratories; Lincolnshire, Ill: 2005
-
(2005)
-
-
Takeda Laboratories1
-
118
-
-
33645402334
-
Melatonin receptors in humans: Biological role and clinical relevance
-
Ekmekcioglu C. Melatonin receptors in humans: biological role and clinical relevance. Biomed Pharmacother 2006;60:97-108
-
(2006)
Biomed. Pharmacother.
, vol.60
, pp. 97-108
-
-
Ekmekcioglu, C.1
-
119
-
-
19544392986
-
Study of the absorbtion, metabolism and excretion of ramelteon (TAK-375) [abstract
-
Stevenson S, Cornelissen K, Clarke E. Study of the absorbtion, metabolism and excretion of ramelteon (TAK-375) [abstract]. Clin Pharmacol Ther 2004;75:1
-
(2004)
Clin. Pharmacol. Ther.
, vol.75
, pp. 1
-
-
Stevenson, S.1
Cornelissen, K.2
Clarke, E.3
-
120
-
-
19544366192
-
Evaluation of the single and multiple doses pharmacokinetics of ramelteon (TAK-375) in subjects with and without renal impairment [abstract
-
Tolbert DK, Karim A, Zhao Z. Evaluation of the single and multiple doses pharmacokinetics of ramelteon (TAK-375) in subjects with and without renal impairment [abstract]. J Clin Pharmacol 2004;44:1
-
(2004)
J. Clin. Pharmacol.
, vol.44
, pp. 1
-
-
Tolbert, D.K.1
Karim, A.2
Zhao, Z.3
-
121
-
-
19544363895
-
Effects of multiple doses of fluoxetine on the systemic exposure of a single dose of ramelteon (TAK-375) in healthy adults [abstract
-
Sainati SMK, A, Tolbert D. Effects of multiple doses of fluoxetine on the systemic exposure of a single dose of ramelteon (TAK-375) in healthy adults [abstract]. Sleep 2004;27
-
(2004)
Sleep
, vol.27
-
-
Sainati, S.M.K.A.1
Tolbert, D.2
-
122
-
-
19544373072
-
Effects of fluconazole and ketoconazole on the pharmacokinetics of ramelteon (TAK-376) in normal healthy male and female subjects [abstract
-
Karim AT, Tolbert D, Cao C. Effects of fluconazole and ketoconazole on the pharmacokinetics of ramelteon (TAK-376) in normal healthy male and female subjects [abstract]. Sleep 2004;27:2
-
(2004)
Sleep
, vol.27
, pp. 2
-
-
Karim, A.T.1
Tolbert, D.2
Cao, C.3
-
123
-
-
14644426021
-
Ramelteon (TAK-375), a selective MT1/MT2- receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment
-
Roth T, Stubbs C, Walsh JK. Ramelteon (TAK-375), a selective MT1/MT2- receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment. Sleep 2005;28:303-7
-
(2005)
Sleep
, vol.28
, pp. 303-307
-
-
Roth, T.1
Stubbs, C.2
Walsh, J.K.3
-
124
-
-
29844447353
-
An efficacy, safety, and dose-response study of Ramelteon in patients with chronic primary insomnia
-
Erman M, Seiden D, Zammit G, et al. An efficacy, safety, and dose-response study of Ramelteon in patients with chronic primary insomnia. Sleep Med 2006;7:17-24
-
(2006)
Sleep Med..
, vol.7
, pp. 17-24
-
-
Erman, M.1
Seiden, D.2
Zammit, G.3
-
125
-
-
84861414294
-
Double-blind placebo-controlled polysomnography and outpatient trial to evaluate the efficacy of ramelteon in adult patients with chronic insomnia [abstract
-
Zammit GR, Roth T, Erman M. Double-blind placebo-controlled polysomnography and outpatient trial to evaluate the efficacy of ramelteon in adult patients with chronic insomnia [abstract]. Sleep 2006;28:1
-
(2006)
Sleep
, vol.28
, pp. 1
-
-
Zammit, G.R.1
Roth, T.2
Erman, M.3
-
126
-
-
33646925615
-
Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia
-
Roth T, Seiden D, Sainati S, et al. Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia. Sleep Med 2006;7:312-18
-
(2006)
Sleep Med.
, vol.7
, pp. 312-318
-
-
Roth, T.1
Seiden, D.2
Sainati, S.3
-
127
-
-
33947519670
-
Age and gender effects on the pharmacokinetics and pharmacodynamics of ramelteon, a hypnotic agent acting via melatonin receptors MT1 and MT2
-
Greenblatt DJ, Harmatz JS, Karim A. Age and gender effects on the pharmacokinetics and pharmacodynamics of ramelteon, a hypnotic agent acting via melatonin receptors MT1 and MT2. J Clin Pharmacol 2007;47:485-96
-
(2007)
J. Clin. Pharmacol.
, vol.47
, pp. 485-496
-
-
Greenblatt, D.J.1
Harmatz, J.S.2
Karim, A.3
-
128
-
-
0346452179
-
A safety, tolerance and pharmacokinetic study of five single doses of TAK-375 in healthy adults
-
Stubbs C, Karim A. A safety, tolerance and pharmacokinetic study of five single doses of TAK-375 in healthy adults. Sleep 2003;26:1
-
(2003)
Sleep
, vol.26
, pp. 1
-
-
Stubbs, C.1
Karim, A.2
-
129
-
-
33749390304
-
Ramelteon: A novel hypnotic lacking abuse liability and sedative adverse effects
-
Johnson MW, Suess PE, Griffiths RR. Ramelteon: a novel hypnotic lacking abuse liability and sedative adverse effects. Arch Gen Psychiatry 2006;63:1149-57
-
(2006)
Arch. Gen. Psychiatry
, vol.63
, pp. 1149-1157
-
-
Johnson, M.W.1
Suess, P.E.2
Griffiths, R.R.3
-
131
-
-
13444259587
-
Neurochemical properties of ramelteon (TAK-375), a selective MT1/ MT2 receptor agonist
-
Kato K, Hirai K, Nishiyama K, et al. Neurochemical properties of ramelteon (TAK-375), a selective MT1/ MT2 receptor agonist. Neuropharmacology 2005;48:301-10
-
(2005)
Neuropharmacology
, vol.48
, pp. 301-310
-
-
Kato, K.1
Hirai, K.2
Nishiyama, K.3
-
134
-
-
59249087280
-
Melatonin agonist tasimelteon (VEC-162) for transient insomnia after sleep-time shift: Two randomised controlled multicentre trials
-
Rajaratnam SM, Polymeropoulos MH, Fisher DM, et al. Melatonin agonist tasimelteon (VEC-162) for transient insomnia after sleep-time shift: two randomised controlled multicentre trials. Lancet 2009;373:482-91
-
(2009)
Lancet
, vol.373
, pp. 482-491
-
-
Rajaratnam, S.M.1
Polymeropoulos, M.H.2
Fisher, D.M.3
-
135
-
-
68249105543
-
Tasimelteon, a melatonin agonist for the treatment of insomnia and circadian rhythm sleep disorders
-
Hardeland R. Tasimelteon, a melatonin agonist for the treatment of insomnia and circadian rhythm sleep disorders. Curr Opin Investig Drugs 2009;10:691-701
-
(2009)
Curr. Opin. Investig. Drugs
, vol.10
, pp. 691-701
-
-
Hardeland, R.1
-
136
-
-
80052849856
-
Agomelatine: A narrative review
-
Demyttenaere K. Agomelatine: a narrative review. Eur Neuropsychopharmacol 2011;21(Suppl 4):S703-9
-
(2011)
Eur. Neuropsychopharmacol.
, vol.21
, Issue.SUPPL. 4
-
-
Demyttenaere, K.1
-
137
-
-
67649418003
-
Influence of the novel antidepressant and melatonin agonist/ serotonin2C receptor antagonist, agomelatine, on the rat sleep-wake cycle architecture
-
Descamps A, Rousset C, Millan MJ, et al. Influence of the novel antidepressant and melatonin agonist/ serotonin2C receptor antagonist, agomelatine, on the rat sleep-wake cycle architecture. Psychopharmacology 2009;205:93-106
-
(2009)
Psychopharmacology
, vol.205
, pp. 93-106
-
-
Descamps, A.1
Rousset, C.2
Millan, M.J.3
-
138
-
-
24144461633
-
Phase-shifts of 24-h rhythms of hormonal release and body temperature following early evening administration of the melatonin agonist agomelatine in healthy older men
-
Leproult R, Van Onderbergen A, L'Hermite-Baleriaux M, et al. Phase-shifts of 24-h rhythms of hormonal release and body temperature following early evening administration of the melatonin agonist agomelatine in healthy older men. Clin Endocrinol 2005;63:298-304
-
(2005)
Clin. Endocrinol.
, vol.63
, pp. 298-304
-
-
Leproult, R.1
Van Onderbergen, A.2
L'Hermite-Baleriaux, M.3
-
139
-
-
11144334174
-
Drugs used to treat insomnia in 2002: Regulatory-based rather than evidence-based medicine
-
Walsh JK. Drugs used to treat insomnia in 2002: regulatory-based rather than evidence-based medicine. Sleep 2004;27:1441-2
-
(2004)
Sleep
, vol.27
, pp. 1441-442
-
-
Walsh, J.K.1
-
140
-
-
17844392614
-
A review of the evidence for the efficacy and safety of trazodone in insomnia
-
Mendelson WB. A review of the evidence for the efficacy and safety of trazodone in insomnia. J Clin Psychiatry 2005;66:469-76
-
(2005)
J. Clin. Psychiatry
, vol.66
, pp. 469-476
-
-
Mendelson, W.B.1
-
141
-
-
7144226575
-
Subjective hypnotic efficacy of trazodone and zolpidem in DSM-III-R primary insomnia
-
Walsh JKE, Erman M, Erwin CW. Subjective hypnotic efficacy of trazodone and zolpidem in DSM-III-R primary insomnia. Hum Psychopharmacol 1998;13:8
-
(1998)
Hum. Psychopharmacol.
, vol.13
, pp. 8
-
-
Walsh, J.K.E.1
Erman, M.2
Erwin, C.W.3
-
142
-
-
0031659471
-
Effects of trazodone hydrochloride and imipramine on polysomnography in healthy subjects
-
Yamadera H, Nakamura S, Suzuki H, Endo S. Effects of trazodone hydrochloride and imipramine on polysomnography in healthy subjects. Psychiatry Clin Neurosci 1998;52:439-43
-
(1998)
Psychiatry Clin. Neurosci.
, vol.52
, pp. 439-443
-
-
Yamadera, H.1
Nakamura, S.2
Suzuki, H.3
Endo, S.4
-
143
-
-
0020556153
-
Trazodone enhances sleep in subjective quality but not in objective duration
-
Montgomery I, Oswald I, Morgan K, Adam K. Trazodone enhances sleep in subjective quality but not in objective duration. Br J Clin Pharmacol 1983;16:139-44
-
(1983)
Br. J. Clin. Pharmacol.
, vol.16
, pp. 139-144
-
-
Montgomery, I.1
Oswald, I.2
Morgan, K.3
Adam, K.4
-
144
-
-
0023840023
-
Priapism associated with trazodone therapy
-
Carson CC III, Mino RD. Priapism associated with trazodone therapy. The Journal of Urology 1988;139:369-70
-
(1988)
Journal of Urology
, vol.139
, pp. 369-370
-
-
Carson III, C.C.1
Mino, R.D.2
-
145
-
-
39749195271
-
Most commonly used drugs to treat insomnia in 2002
-
Compton-Mcbride SS, Schweitzer PK, Walsh JK. Most commonly used drugs to treat insomnia in 2002. Sleep 2004;27(Suppl):1
-
(2004)
Sleep
, vol.27
, Issue.SUPPL.
, pp. 1
-
-
Compton-Mcbride, S.S.1
Schweitzer, P.K.2
Walsh, J.K.3
-
146
-
-
18644379522
-
Trimipramine in primary insomnia: Results of a polysomnographic double-blind controlled study
-
Riemann D, Voderholzer U, Cohrs S, et al. Trimipramine in primary insomnia: results of a polysomnographic double-blind controlled study. Pharmacopsychiatry 2002;35:165-74
-
(2002)
Pharmacopsychiatry
, vol.35
, pp. 165-174
-
-
Riemann, D.1
Voderholzer, U.2
Cohrs, S.3
-
147
-
-
0028070902
-
Treatment of primary insomnia with trimipramine: An alternative to benzodiazepine hypnotics
-
Hohagen F, Montero RF, Weiss E, et al. Treatment of primary insomnia with trimipramine: an alternative to benzodiazepine hypnotics? Eur Arch Psychiatry Clin Neurosci 1994;244:65-72
-
(1994)
Eur. Arch. Psychiatry Clin. Neurosci.
, vol.244
, pp. 65-72
-
-
Hohagen, F.1
Montero, R.F.2
Weiss, E.3
-
148
-
-
3543069021
-
Comparative effects of mirtazapine and fluoxetine on sleep physiology measures in patients with major depression and insomnia
-
Winokur A, DeMartinis NA III, McNally DP, et al. Comparative effects of mirtazapine and fluoxetine on sleep physiology measures in patients with major depression and insomnia. J Clin Psychiatry 2003;64:1224-9
-
(2003)
J. Clin. Psychiatry
, vol.64
, pp. 1224-229
-
-
Winokur, A.1
DeMartinis III, N.A.2
McNally, D.P.3
-
149
-
-
0036977524
-
Effects of mirtazapine on sleep polygraphic variables in major depression
-
Schittecatte M, Dumont F, Machowski R, et al. Effects of mirtazapine on sleep polygraphic variables in major depression. Neuropsychobiology 2002;46:197-201
-
(2002)
Neuropsychobiology
, vol.46
, pp. 197-201
-
-
Schittecatte, M.1
Dumont, F.2
Machowski, R.3
-
150
-
-
0034237749
-
Acute effects of mirtazapine on sleep continuity and sleep architecture in depressed patients: A pilot study
-
Winokur A, Sateia MJ, Hayes JB, et al. Acute effects of mirtazapine on sleep continuity and sleep architecture in depressed patients: a pilot study. Biol Psychiatry 2000;48:75-8
-
(2000)
Biol. Psychiatry
, vol.48
, pp. 75-78
-
-
Winokur, A.1
Sateia, M.J.2
Hayes, J.B.3
-
151
-
-
0021963570
-
A double-blind group comparative study using the new anti-depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery
-
Sorensen M, Jorgensen J, Viby-Mogensen J, et al. A double-blind group comparative study using the new anti-depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery. Acta Psychiatr Scand 1985;71:339-46
-
(1985)
Acta. Psychiatr. Scand.
, vol.71
, pp. 339-346
-
-
Sorensen, M.1
Jorgensen, J.2
Viby-Mogensen, J.3
-
152
-
-
0346973887
-
The sleep-improving effects of doxepin are paralleled by a normalized plasma cortisol secretion in primary insomnia A placebo-controlled, double-blind, randomized, cross-over study followed by an open treatment over 3 weeks
-
Rodenbeck A, Cohrs S, Jordan W, et al. The sleep-improving effects of doxepin are paralleled by a normalized plasma cortisol secretion in primary insomnia. A placebo-controlled, double-blind, randomized, cross-over study followed by an open treatment over 3 weeks. Psychopharmacology (Berl) 2003;170:423-8
-
(2003)
Psychopharmacology (Berl.
, vol.170
, pp. 423-428
-
-
Rodenbeck, A.1
Cohrs, S.2
Jordan, W.3
-
153
-
-
0029811453
-
Nocturnal melatonin secretion and sleep after doxepin administration in chronic primary insomnia
-
Hajak G, Rodenbeck A, Adler L, et al. Nocturnal melatonin secretion and sleep after doxepin administration in chronic primary insomnia. Pharmacopsychiatry 1996;29:187-92
-
(1996)
Pharmacopsychiatry
, vol.29
, pp. 187-192
-
-
Hajak, G.1
Rodenbeck, A.2
Adler, L.3
-
154
-
-
0034905737
-
Doxepin in the treatment of primary insomnia: A placebo-controlled, double-blind, polysomnographic study
-
Hajak G, Rodenbeck A, Voderholzer U, et al. Doxepin in the treatment of primary insomnia: a placebo-controlled, double-blind, polysomnographic study. J Clin Psychiatry 2001;62:453-63
-
(2001)
J. Clin. Psychiatry
, vol.62
, pp. 453-463
-
-
Hajak, G.1
Rodenbeck, A.2
Voderholzer, U.3
-
156
-
-
78649842406
-
Efficacy and safety of doxepin 1 mg and 3 mg in a 12-week sleep laboratory and outpatient trial of elderly subjects with chronic primary insomnia
-
Krystal AD, Durrence HH, Scharf M, et al. Efficacy and safety of doxepin 1 mg and 3 mg in a 12-week sleep laboratory and outpatient trial of elderly subjects with chronic primary insomnia. Sleep 2010;33:1553-61
-
(2010)
Sleep
, vol.33
, pp. 1553-1561
-
-
Krystal, A.D.1
Durrence, H.H.2
Scharf, M.3
-
157
-
-
0033029111
-
Olanzapine acute administration in schizophrenic patients increases delta sleep and sleep efficiency
-
Salin-Pascual RJ, Herrera-Estrella M, Galicia Polo L. Olanzapine acute administration in schizophrenic patients increases delta sleep and sleep efficiency. Biol Psychiatry 1999;46:3
-
(1999)
Biol. Psychiatry
, vol.46
, pp. 3
-
-
Salin-Pascual, R.J.1
Herrera-Estrella, M.2
Galicia Polo, L.3
-
158
-
-
33644659911
-
Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia
-
Walsh JK, Perlis M, Rosenthal M, et al. Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia. J Clin Sleep Med 2006;2:35-41
-
(2006)
J. Clin. Sleep Med.
, vol.2
, pp. 35-41
-
-
Walsh, J.K.1
Perlis, M.2
Rosenthal, M.3
-
159
-
-
33745793049
-
Effect of tiagabine on sleep in elderly subjectswith primary insomnia: A randomized, double-blind, placebo-controlled study
-
Roth T, Wright KP Jr, Walsh J. Effect of tiagabine on sleep in elderly subjectswith primary insomnia: a randomized, double-blind, placebo-controlled study. Sleep 2006;29:335-41
-
(2006)
Sleep
, vol.29
, pp. 335-341
-
-
Roth, T.1
Wright Jr., K.P.2
Walsh, J.3
-
160
-
-
33947695768
-
Effect of short-term treatment with gaboxadol on sleep maintenance and initiation in patients with primary insomnia
-
Deacon S, Staner L, Staner C, et al. Effect of short-term treatment with gaboxadol on sleep maintenance and initiation in patients with primary insomnia. Sleep 2007;30:281-7
-
(2007)
Sleep
, vol.30
, pp. 281-287
-
-
Deacon, S.1
Staner, L.2
Staner, C.3
-
161
-
-
35248886132
-
Short-term treatment with gaboxadol improves sleep maintenance and enhances slow wave sleep in adult patients with primary insomnia
-
Lundahl J, Staner L, Staner C, et al. Short-term treatment with gaboxadol improves sleep maintenance and enhances slow wave sleep in adult patients with primary insomnia. Psychopharmacology (Berl) 2007;195:139-46
-
(2007)
Psychopharmacology (Berl.
, vol.195
, pp. 139-146
-
-
Lundahl, J.1
Staner, L.2
Staner, C.3
-
162
-
-
0033799076
-
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors
-
Herrick-Davis K, Grinde E, Teitler M. Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors. J Pharmacol Exp Ther 2000;295:226-32
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 226-232
-
-
Herrick-Davis, K.1
Grinde, E.2
Teitler, M.3
-
163
-
-
80053146959
-
Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo
-
Yadav PN, Kroeze WK, Farrell MS, Roth BL. Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo. J Pharmacol Exp Ther 2011;339:99-105
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.339
, pp. 99-105
-
-
Yadav, P.N.1
Kroeze, W.K.2
Farrell, M.S.3
Roth, B.L.4
-
164
-
-
79251616591
-
Pimavanserin tartrate, a 5-HT(2A) receptor inverse agonist, increases slow wave sleep as measured by polysomnography in healthy adult volunteers
-
Ancoli-Israel S, Vanover KE, Weiner DM, et al. Pimavanserin tartrate, a 5-HT(2A) receptor inverse agonist, increases slow wave sleep as measured by polysomnography in healthy adult volunteers. Sleep Med 2011;12:134-41
-
(2011)
Sleep Med.
, vol.12
, pp. 134-141
-
-
Ancoli-Israel, S.1
Vanover, K.E.2
Weiner, D.M.3
-
165
-
-
73949098111
-
Nelotanserin, a novel selective human 5-hydroxytryptamine2A inverse agonist for the treatment of insomnia
-
Al-Shamma HA, Anderson C, Chuang E, et al. Nelotanserin, a novel selective human 5-hydroxytryptamine2A inverse agonist for the treatment of insomnia. J Pharmacol Exp Ther 2010;332:281-90
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.332
, pp. 281-290
-
-
Al-Shamma, H.A.1
Anderson, C.2
Chuang, E.3
-
166
-
-
20444450115
-
Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs
-
Abrams JK, Johnson PL, Hay-Schmidt A, et al. Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs. Neuroscience 2005;133:983-97
-
(2005)
Neuroscience
, vol.133
, pp. 983-997
-
-
Abrams, J.K.1
Johnson, P.L.2
Hay-Schmidt, A.3
-
167
-
-
35748966419
-
GABA A/Bz receptor subtypes as targets for selective drugs
-
Da Settimo F, Taliani S, Trincavelli ML, et al. GABA A/Bz receptor subtypes as targets for selective drugs. Curr Med Chem 2007;14:2680-701
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 2680-701
-
-
Da Settimo, F.1
Taliani, S.2
Trincavelli, M.L.3
-
168
-
-
79951994324
-
Orexin receptors: Pharmacology and therapeutic opportunities
-
Scammell TE, Winrow CJ. Orexin receptors: pharmacology and therapeutic opportunities. Annu Rev Pharmacol Toxicol 2011;51:243-66
-
(2011)
Annu. Rev. Pharmacol. Toxicol.
, vol.51
, pp. 243-266
-
-
Scammell, T.E.1
Winrow, C.J.2
-
169
-
-
77649157819
-
Orexin receptor antagonists: A review of promising compounds patented since 2006
-
Coleman PJ, Renger JJ. Orexin receptor antagonists: a review of promising compounds patented since 2006. Expert Opinion Ther Patents 2010;20:307-24
-
(2010)
Expert Opinion Ther. Patents.
, vol.20
, pp. 307-324
-
-
Coleman, P.J.1
Renger, J.J.2
-
171
-
-
48249109864
-
Orexin receptor antagonists: Medicinal chemistry and therapeutic potential
-
Roecker AJ, Coleman PJ. Orexin receptor antagonists: medicinal chemistry and therapeutic potential. Curr Top Med Chem 2008;8:977-87
-
(2008)
Curr. Top. Med. Chem.
, vol.8
, pp. 977-987
-
-
Roecker, A.J.1
Coleman, P.J.2
-
172
-
-
64349107463
-
Biomedical application of orexin/ hypocretin receptor ligands in neuroscience
-
Boss C, Brisbare-Roch C, Jenck F. Biomedical application of Orexin/ Hypocretin receptor ligands in neuroscience. J Med Chem 2009;52:891-903
-
(2009)
J. Med. Chem.
, vol.52
, pp. 891-903
-
-
Boss, C.1
Brisbare-Roch, C.2
Jenck, F.3
-
173
-
-
84873067212
-
Efficacy and tolerability of the dual orexin receptor antagonist MK-4305 in patients with primary insomnia: Randomized, controlled, adaptive crossover polysomnography study
-
5 - 9 June; San Antonio, Texas; 2010
-
Herring W.J.B.Budd K.S.Hutzelmann J.et al. Efficacy and tolerability of the dual orexin receptor antagonist MK-4305 in patients with primary insomnia: Randomized, controlled, adaptive crossover polysomnography study Presented at SLEEP 2010, 24th Assoc. Prof. Sleep Soc.; 5 - 9 June; San Antonio, Texas; 2010
-
Presented at SLEEP 2010 24th Assoc. Prof. Sleep Soc.
-
-
Herring, W.J.B.1
Budd, K.S.2
Hutzelmann, J.3
-
174
-
-
58149379222
-
Proof-of-concept study in primary insomnia patients with almorexant (ACT-078573), a dual orexin receptor antagonist
-
2 - 6 September; Cairns, Austria;
-
Dingemanse JD, Dorffner G, Hajak G, et al. Proof-of-concept study in primary insomnia patients with almorexant (ACT-078573), a dual orexin receptor antagonist. Presented at WorldSleep 07, 5th International Congress of the World Federation of Sleep Research and Sleep Medicine Societies; 2 - 6 September; Cairns, Austria; 2007
-
(2007)
Presented at WorldSleep 07, 5th International Congress of the World Federation of Sleep Research and Sleep Medicine Societies
-
-
Dingemanse, J.D.1
Dorffner, G.2
Hajak, G.3
-
175
-
-
79952978794
-
Bis-amido piperidine derivatives as in vitro and in vivo potent dual orexin receptor antagonists
-
16 - 20 August; Washington, D.C;
-
Di Fabio RG, Gerrard P, Porter R, et al. Bis-amido piperidine derivatives as in vitro and in vivo potent dual orexin receptor antagonists. Presented at 238th ACS Natl. Meeting; 16 - 20 August; Washington, D.C; 2009
-
(2009)
Presented at 238th ACS Natl. Meeting
-
-
Di Fabio, R.G.1
Gerrard, P.2
Porter, R.3
-
176
-
-
84858337352
-
Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist
-
Epub ahead of print]
-
Bettica P, Nucci G, Pyke C, et al. Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist. J Psychopharmacol 2011. [Epub ahead of print]
-
(2011)
J. Psychopharmacol.
-
-
Bettica, P.1
Nucci, G.2
Pyke, C.3
-
178
-
-
79951991696
-
Discovery of MK-4305: A novel orexin receptor antagonist for the treatment of insomnia
-
21 - 25 March; San Francisco, CA;
-
Di Fabio RG, Gerrard P, Porter R, et al. Bis-amido piperidine derivatives as in vitro and in vivo potent dual orexin receptor antagonists. Presented at 238th ACS Natl. Meeting; 16 - 20 August; Washington, D.C; 2009
-
(2010)
Presented at 239th ACS National Meeting
-
-
Coleman, P.C.1
Cox, C.2
Breslin, M.3
-
182
-
-
0027070394
-
New epidemiologic findings about insomnia and its treatment
-
34-39; discussion
-
Balter MB, Uhlenhuth EH. New epidemiologic findings about insomnia and its treatment. J Clin Psychiatry 1992;53(Suppl):34-39; discussion 40-32
-
(1992)
J. Clin. Psychiatry
, vol.53
, Issue.SUPPL.
, pp. 40-32
-
-
Balter, M.B.1
Uhlenhuth, E.H.2
-
183
-
-
0031663348
-
Heart rate variability in insomniacs and matched normal sleepers
-
Bonnet MH, Arand DL. Heart rate variability in insomniacs and matched normal sleepers. Psychosom Med 1998;60:610-15
-
(1998)
Psychosom. Med.
, vol.60
, pp. 610-615
-
-
Bonnet, M.H.1
Arand, D.L.2
|