메뉴 건너뛰기




Volumn 10, Issue 2, 2010, Pages 305-318

Melatonin agonists and insomnia

Author keywords

Circadian rhythm sleep disorders; Insomnia; Melatonin; Melatonin agonists; Sleep

Indexed keywords

AGOMELATINE; BENZODIAZEPINE; HYPNOTIC AGENT; MELATONIN; MELATONIN DERIVATIVE; MELATONIN RECEPTOR; N[[2 (2,3 DIHYDRO 4 BENZOFURANYL)CYCLOPROPOYL]METHYL]PROPANAMIDE; PLACEBO; PROPIONAMIDE DERIVATIVE; RAMELTEON; UNCLASSIFIED DRUG;

EID: 76249120626     PISSN: 14737175     EISSN: 17448360     Source Type: Journal    
DOI: 10.1586/ern.10.1     Document Type: Review
Times cited : (56)

References (119)
  • 2
    • 0028018966 scopus 로고
    • Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses
    • Reppert SM, Weaver DR, Ebisawa T. Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron 13(5), 1177-1185 (1994).
    • (1994) Neuron , vol.13 , Issue.5 , pp. 1177-1185
    • Reppert, S.M.1    Weaver, D.R.2    Ebisawa, T.3
  • 3
    • 59249098005 scopus 로고    scopus 로고
    • Let there be sleep - on time
    • Cardinali DP, Golombek DA. Let there be sleep - on time. Lancet 373, 438-440 (2009).
    • (2009) Lancet , vol.373 , pp. 438-440
    • Cardinali, D.P.1    Golombek, D.A.2
  • 4
    • 0024673582 scopus 로고
    • The mammalian circadian system: Models and physiology
    • Rusak B. The mammalian circadian system: models and physiology. J. Biol. Rhythms 4(2), 121-134 (1989).
    • (1989) J. Biol. Rhythms , vol.4 , Issue.2 , pp. 121-134
    • Rusak, B.1
  • 5
    • 0018713686 scopus 로고
    • Persistence of circadian rhythmicity in a mammalian hypothalamic "island" containing the suprachiasmatic nucleus
    • Inouye S-I, Kawamura H. Persistence of circadian rhythmicity in a mammalian hypothalamic "island" containing the suprachiasmatic nucleus. Proc. Natl Acad. Sci. USA 76(11), 5962-5966 (1979).
    • (1979) Proc. Natl Acad. Sci. USA , vol.76 , Issue.11 , pp. 5962-5966
    • Inouye, S.-I.1    Kawamura, H.2
  • 6
    • 36348971784 scopus 로고    scopus 로고
    • The circadian clockwork of the suprachiasmatic nuclei - analysis of a cellular oscillator that drives endocrine rhythms
    • Maywood ES, O'Neill JS, Chesham JE, Hastings MH. The circadian clockwork of the suprachiasmatic nuclei - analysis of a cellular oscillator that drives endocrine rhythms. Endocrinology 148(12), 5624-5634 (2007).
    • (2007) Endocrinology , vol.148 , Issue.12 , pp. 5624-5634
    • Maywood, E.S.1    O'Neill, J.S.2    Chesham, J.E.3    Hastings, M.H.4
  • 7
    • 0034423409 scopus 로고    scopus 로고
    • Life's 24-hour clock: Molecular control of circadian rhythms in animal cells
    • Young MY. Life's 24-hour clock: molecular control of circadian rhythms in animal cells. Trends Biochem. Sci. 25, 601-606 (2000).
    • (2000) Trends Biochem. Sci , vol.25 , pp. 601-606
    • Young, M.Y.1
  • 10
    • 0035923723 scopus 로고    scopus 로고
    • Intrinsic near-24-h pacemaker period determines limits of circadian entrainment to a weak synchronizer in humans
    • Wright KP, Hughes RJ, Kronauer RE, Dijk D, Czeisler CA. Intrinsic near-24-h pacemaker period determines limits of circadian entrainment to a weak synchronizer in humans. Proc. Natl Acad. Sci. USA 98(24), 14027-14032 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , Issue.24 , pp. 14027-14032
    • Wright, K.P.1    Hughes, R.J.2    Kronauer, R.E.3    Dijk, D.4    Czeisler, C.A.5
  • 11
    • 0023748529 scopus 로고
    • Melatonin
    • Arendt J. Melatonin. Clin. Endocrinol. 29, 205-229 (1988).
    • (1988) Clin. Endocrinol , vol.29 , pp. 205-229
    • Arendt, J.1
  • 13
    • 0030069491 scopus 로고    scopus 로고
    • Chronobiotics - drugs that shift rhythms
    • Dawson D, Armstrong SM. Chronobiotics - drugs that shift rhythms. Pharmacol. Ther. 69(1), 15-36 (1996).
    • (1996) Pharmacol. Ther , vol.69 , Issue.1 , pp. 15-36
    • Dawson, D.1    Armstrong, S.M.2
  • 14
    • 11844293488 scopus 로고    scopus 로고
    • Melatonin as a chronobiotic
    • Arendt J, Skene DJ. Melatonin as a chronobiotic. Sleep Med. Rev. 9, 25-39 (2005).
    • (2005) Sleep Med. Rev , vol.9 , pp. 25-39
    • Arendt, J.1    Skene, D.J.2
  • 15
    • 0030784666 scopus 로고    scopus 로고
    • Melatonin: A sleep-promoting hormone
    • Zhdanova IV, Lynch HJ, Wurtman RJ. Melatonin: a sleep-promoting hormone. Sleep 20, 899-907 (1997).
    • (1997) Sleep , vol.20 , pp. 899-907
    • Zhdanova, I.V.1    Lynch, H.J.2    Wurtman, R.J.3
  • 16
    • 0029972613 scopus 로고    scopus 로고
    • Melatonin receptors step into the light: Cloning and classification of subtypes
    • Reppert SM, Weaver DR, Godson C. Melatonin receptors step into the light: cloning and classification of subtypes. Trends Pharmacol. Sci. 17(3), 100-102 (1996).
    • (1996) Trends Pharmacol. Sci , vol.17 , Issue.3 , pp. 100-102
    • Reppert, S.M.1    Weaver, D.R.2    Godson, C.3
  • 17
    • 36248957048 scopus 로고    scopus 로고
    • Melatonin receptors: Role on sleep and circadian rhythm regulation
    • Dubocovich ML. Melatonin receptors: role on sleep and circadian rhythm regulation. Sleep Med. 8(Suppl. 3), 34-42 (2007).
    • (2007) Sleep Med , vol.8 , Issue.SUPPL. 3 , pp. 34-42
    • Dubocovich, M.L.1
  • 18
    • 59249087280 scopus 로고    scopus 로고
    • Melatonin agonist tasimelteon (VEC-192) for transient insomnia after sleep-time shift: Two randomised controlled multicentre trials
    • Rajaratnam SMW, Polymeropolous MH, Fisher DM et al. Melatonin agonist tasimelteon (VEC-192) for transient insomnia after sleep-time shift: two randomised controlled multicentre trials. Lancet 373(9662), 482-491 (2009).
    • (2009) Lancet , vol.373 , Issue.9662 , pp. 482-491
    • Rajaratnam, S.M.W.1    Polymeropolous, M.H.2    Fisher, D.M.3
  • 19
    • 13444259587 scopus 로고    scopus 로고
    • Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist
    • Kato K, Hirai K, Nishiyama K et al. Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist. Neuropharmacology 48(2), 301-310 (2005).
    • (2005) Neuropharmacology , vol.48 , Issue.2 , pp. 301-310
    • Kato, K.1    Hirai, K.2    Nishiyama, K.3
  • 20
    • 0031054011 scopus 로고    scopus 로고
    • Melatonin action and signal transduction in the rat suprachiasmatic circadian clock: Activation of protein kinase C at dusk and dawn
    • McArthur AJ, Hunt AE, Gillette MU. Melatonin action and signal transduction in the rat suprachiasmatic circadian clock: activation of protein kinase C at dusk and dawn. Endocrinology 138(2), 627-634 (1997).
    • (1997) Endocrinology , vol.138 , Issue.2 , pp. 627-634
    • McArthur, A.J.1    Hunt, A.E.2    Gillette, M.U.3
  • 21
    • 0032161469 scopus 로고    scopus 로고
    • Selective MT2 melatonin receptor anatagonists block melatonin-mediated phase advances of circadian rhythms
    • Dubocovich ML, Yun K, Alghoul WM, Benloucif S, Masana MI. Selective MT2 melatonin receptor anatagonists block melatonin-mediated phase advances of circadian rhythms. FASEBJ. 12(12), 1211-1220 (1998).
    • (1998) FASEBJ , vol.12 , Issue.12 , pp. 1211-1220
    • Dubocovich, M.L.1    Yun, K.2    Alghoul, W.M.3    Benloucif, S.4    Masana, M.I.5
  • 22
    • 23744445174 scopus 로고    scopus 로고
    • Effect of MT1 melatonin receptor deletion on melatonin-mediated phase shift of circadian rhythms in the c57BL/6 mouse
    • Dubocovich ML, Hudson RL, Sumaya IC, Masan MI, Manna E. Effect of MT1 melatonin receptor deletion on melatonin-mediated phase shift of circadian rhythms in the c57BL/6 mouse. J. Pineal Res. 39(2), 113-120 (2005).
    • (2005) J. Pineal Res , vol.39 , Issue.2 , pp. 113-120
    • Dubocovich, M.L.1    Hudson, R.L.2    Sumaya, I.C.3    Masan, M.I.4    Manna, E.5
  • 23
    • 0031299111 scopus 로고    scopus 로고
    • Circadian entrainment and phase shifting in mammals with melatonin
    • Redman JR. Circadian entrainment and phase shifting in mammals with melatonin. J. Biol. Rhythms 12(6), 581-587 (1997).
    • (1997) J. Biol. Rhythms , vol.12 , Issue.6 , pp. 581-587
    • Redman, J.R.1
  • 24
    • 66449112190 scopus 로고    scopus 로고
    • Rajaratnam SMW, Cohen DA, Rogers NL. Melatonin and melatonin analogues. Sleep Med. Clin. 4(2), 179-193 (2009).
    • Rajaratnam SMW, Cohen DA, Rogers NL. Melatonin and melatonin analogues. Sleep Med. Clin. 4(2), 179-193 (2009).
  • 25
    • 33846239400 scopus 로고    scopus 로고
    • The brain's master circadian clock: Implications and opportunities for therapy of sleep disorders
    • Zee P, Manthena P. The brain's master circadian clock: Implications and opportunities for therapy of sleep disorders. Sleep Med. Rev. 11, 59-70 (2007).
    • (2007) Sleep Med. Rev , vol.11 , pp. 59-70
    • Zee, P.1    Manthena, P.2
  • 26
    • 0033179129 scopus 로고    scopus 로고
    • Complex effects of melatonin: Evidence for photoperiodic responses in humans?
    • Arendt J, Middleton B, Stone B, Skene DJ. Complex effects of melatonin: Evidence for photoperiodic responses in humans? Sleep 22(5), 625-635 (1999).
    • (1999) Sleep , vol.22 , Issue.5 , pp. 625-635
    • Arendt, J.1    Middleton, B.2    Stone, B.3    Skene, D.J.4
  • 27
    • 38149086823 scopus 로고    scopus 로고
    • A three pulse phase response curve to three milligrams of melatonin in humans
    • Burgess HJ, Revell VL, Eastman CI. A three pulse phase response curve to three milligrams of melatonin in humans. J. Physiol. 586(2), 639-647 (2008).
    • (2008) J. Physiol , vol.586 , Issue.2 , pp. 639-647
    • Burgess, H.J.1    Revell, V.L.2    Eastman, C.I.3
  • 28
    • 0031911537 scopus 로고    scopus 로고
    • The human phase response curve (PRC) to melatonin is about 12 hours out of phase with the PRC to light
    • Lewy AJ, Bauer VK, Ahmed S et al. The human phase response curve (PRC) to melatonin is about 12 hours out of phase with the PRC to light. Chronobiol. Int. 15(1), 71-83 (1998).
    • (1998) Chronobiol. Int , vol.15 , Issue.1 , pp. 71-83
    • Lewy, A.J.1    Bauer, V.K.2    Ahmed, S.3
  • 29
    • 0003036978 scopus 로고
    • Free-running melatonin rhythms in blind people: Phase shifts with melatonin and triazolam administration
    • Rensing, L, an der Heiden, U, Mackey, MC Eds, Springer-Verlag, Heidelberg, Germany
    • Sack RL, Lewy AJ, Hoban TM. Free-running melatonin rhythms in blind people: phase shifts with melatonin and triazolam administration. In: Temporal Disorder in Human Oscillatory Systems. Rensing, L, an der Heiden, U, Mackey, MC (Eds). Springer-Verlag, Heidelberg, Germany 219-224 (1987).
    • (1987) Temporal Disorder in Human Oscillatory Systems , pp. 219-224
    • Sack, R.L.1    Lewy, A.J.2    Hoban, T.M.3
  • 30
    • 0027999153 scopus 로고
    • Acute phase-shifting effects of melatonin associated with suppression of core body temperature in humans
    • Deacon S, English J, Arendt J. Acute phase-shifting effects of melatonin associated with suppression of core body temperature in humans. Neurosci. Lett. 178, 32-34 (1994).
    • (1994) Neurosci. Lett , vol.178 , pp. 32-34
    • Deacon, S.1    English, J.2    Arendt, J.3
  • 31
    • 0030910807 scopus 로고    scopus 로고
    • Early evening melatonin and S-20098 advance circadian phase and nocturnal regulation of core body temperature
    • Krauchi K, Cajochen C, Mori D, Graw P, Wirz-Justice A. Early evening melatonin and S-20098 advance circadian phase and nocturnal regulation of core body temperature. Am. J. Physiol. 272(4 Pt 2), R1178-R1188 (1997).
    • (1997) Am. J. Physiol , vol.272 , Issue.4 PART 2
    • Krauchi, K.1    Cajochen, C.2    Mori, D.3    Graw, P.4    Wirz-Justice, A.5
  • 32
    • 0141787946 scopus 로고    scopus 로고
    • Melatonin phase-shifts human circadian rhythms with no evidence of changes in the duration of endogenous melatonin secretion ot the 24-hour production of reproductive hormones
    • Rajaratnam SMW, Dijk D, Middleton B, Stone BM, Arendt J. Melatonin phase-shifts human circadian rhythms with no evidence of changes in the duration of endogenous melatonin secretion ot the 24-hour production of reproductive hormones. J. Clin. Endocrinol. Metabol. 88(9), 4303-4309 (2003).
    • (2003) J. Clin. Endocrinol. Metabol , vol.88 , Issue.9 , pp. 4303-4309
    • Rajaratnam, S.M.W.1    Dijk, D.2    Middleton, B.3    Stone, B.M.4    Arendt, J.5
  • 33
    • 33749515245 scopus 로고    scopus 로고
    • Human circadian rhythms: Physiological and therapeutic relevance of light and melatonin
    • Skene DJ, Arendt J. Human circadian rhythms: physiological and therapeutic relevance of light and melatonin. Ann. Clin. Biochem. 43(Pt 5), 344-353 (2006).
    • (2006) Ann. Clin. Biochem , vol.43 , Issue.PART 5 , pp. 344-353
    • Skene, D.J.1    Arendt, J.2
  • 34
    • 0023834995 scopus 로고    scopus 로고
    • Reentrainmnet of rat circadian activity rhythms: Effects of melatonin
    • Redman JR, Armstrong SM. Reentrainmnet of rat circadian activity rhythms: effects of melatonin. J. Pineal Res. 5(2), 203-215 (1998).
    • (1998) J. Pineal Res , vol.5 , Issue.2 , pp. 203-215
    • Redman, J.R.1    Armstrong, S.M.2
  • 35
    • 12244286055 scopus 로고    scopus 로고
    • Ramelteon (TAK-375) accelerates reentrainment of circadian rhythm after a phase advance of the light-dark cycle in rats
    • Hirai K, Kita M, Ohta H et al. Ramelteon (TAK-375) accelerates reentrainment of circadian rhythm after a phase advance of the light-dark cycle in rats. J. Biol. Rhythms 20(1), 27-37 (2005).
    • (2005) J. Biol. Rhythms , vol.20 , Issue.1 , pp. 27-37
    • Hirai, K.1    Kita, M.2    Ohta, H.3
  • 36
    • 55349134900 scopus 로고    scopus 로고
    • Circadian phase-shifting effects of repeated ramelteon administration in healthy adults
    • Richardson GS, Zee PC, Wang-Weigand S, Rodriguez L, Peng X. Circadian phase-shifting effects of repeated ramelteon administration in healthy adults. J. Clin. Sleep Med. 4(5), 456-461 (2008).
    • (2008) J. Clin. Sleep Med , vol.4 , Issue.5 , pp. 456-461
    • Richardson, G.S.1    Zee, P.C.2    Wang-Weigand, S.3    Rodriguez, L.4    Peng, X.5
  • 37
    • 0037382825 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics and metabolism of BMS-214778, a novel melatonin receptor agonist
    • Vachharajani NN, Yeleswaram K, Boutlon DW. Preclinical pharmacokinetics and metabolism of BMS-214778, a novel melatonin receptor agonist. J. Pharm. Sci. 92(4), 760-772 (2003).
    • (2003) J. Pharm. Sci , vol.92 , Issue.4 , pp. 760-772
    • Vachharajani, N.N.1    Yeleswaram, K.2    Boutlon, D.W.3
  • 38
    • 0030218832 scopus 로고    scopus 로고
    • Entrainment of circadian rhythms by S-20098, a melatonin agonist, is dose and plasma concentration dependent
    • Martinet L, Guardiola-Lemaitre B, Mocaer E. Entrainment of circadian rhythms by S-20098, a melatonin agonist, is dose and plasma concentration dependent. Pharmacol. Biochem. Behav. 54(4), 713-718 (1996).
    • (1996) Pharmacol. Biochem. Behav , vol.54 , Issue.4 , pp. 713-718
    • Martinet, L.1    Guardiola-Lemaitre, B.2    Mocaer, E.3
  • 39
    • 0032834067 scopus 로고    scopus 로고
    • Organization of rat circadian rhythms during daily infusion of melatonin or S20098, a melatonin agonist
    • Pitrosky B, Kirsch R, Malan A, Mocaer E, Pevet P. Organization of rat circadian rhythms during daily infusion of melatonin or S20098, a melatonin agonist. Am. J. Physiol. 277(3 Pt 2), R812-R828 (1999).
    • (1999) Am. J. Physiol , vol.277 , Issue.3 PART 2
    • Pitrosky, B.1    Kirsch, R.2    Malan, A.3    Mocaer, E.4    Pevet, P.5
  • 40
    • 0027362397 scopus 로고
    • Successful use of S20098 and melatonin in an animal model of delayed sleep-phase syndrome (DSPS)
    • Armstrong SM, McNulty OM, Guardiola-Lemaitre B, Redman JR. Successful use of S20098 and melatonin in an animal model of delayed sleep-phase syndrome (DSPS). Pharmacol. Biochem. Behav. 46(1), 45-49 (1993).
    • (1993) Pharmacol. Biochem. Behav , vol.46 , Issue.1 , pp. 45-49
    • Armstrong, S.M.1    McNulty, O.M.2    Guardiola-Lemaitre, B.3    Redman, J.R.4
  • 41
    • 0028916266 scopus 로고
    • Dose dependent effects of S-20098, a melatonin agonist, on direction of re-entrainment of rat circadian activity rhythms
    • Redman JR, Guardiola-Lemaitre B, Brown M, Delagrange P, Armstrong SM. Dose dependent effects of S-20098, a melatonin agonist, on direction of re-entrainment of rat circadian activity rhythms. Psychopharmacology 118(4), 358-390 (1995).
    • (1995) Psychopharmacology , vol.118 , Issue.4 , pp. 358-390
    • Redman, J.R.1    Guardiola-Lemaitre, B.2    Brown, M.3    Delagrange, P.4    Armstrong, S.M.5
  • 42
    • 24144461633 scopus 로고    scopus 로고
    • Phase-shifts of 24-h rhythms of hormonal release and body temperature following early evening administration of the melatonin agonist agomelatine in healthy older men
    • Leproult R, Van Onderbergen A, L'Hermite-Baleriaux M, Van Cauter E, Copinschi G. Phase-shifts of 24-h rhythms of hormonal release and body temperature following early evening administration of the melatonin agonist agomelatine in healthy older men. Clin. Endocrinol. 63, 298-304 (2005).
    • (2005) Clin. Endocrinol , vol.63 , pp. 298-304
    • Leproult, R.1    Van Onderbergen, A.2    L'Hermite-Baleriaux, M.3    Van Cauter, E.4    Copinschi, G.5
  • 43
    • 0037379973 scopus 로고    scopus 로고
    • Importance and relevance of melatonin to human biological rhythms
    • Arendt J. Importance and relevance of melatonin to human biological rhythms. J. Neuroendocrinol. 15(4), 427-431 (2003).
    • (2003) J. Neuroendocrinol , vol.15 , Issue.4 , pp. 427-431
    • Arendt, J.1
  • 44
    • 11844250002 scopus 로고    scopus 로고
    • Melatonin as a hypnotic: Pro
    • Zhdanova IV. Melatonin as a hypnotic: pro. Sleep Med. Rev. 9(1), 51-65 (2005).
    • (2005) Sleep Med. Rev , vol.9 , Issue.1 , pp. 51-65
    • Zhdanova, I.V.1
  • 45
    • 31944452165 scopus 로고    scopus 로고
    • Reduced sleep efficiency in cervical spinal cord injury: Association with abolished night time melatonin secretion
    • Scheer FA, Zeitzer JM, Ayas NT, R. B, Czeisler CA, Shea JA. Reduced sleep efficiency in cervical spinal cord injury: association with abolished night time melatonin secretion. Spinal Cord 44(2), 78-81 (2006).
    • (2006) Spinal Cord , vol.44 , Issue.2 , pp. 78-81
    • Scheer, F.A.1    Zeitzer, J.M.2    Ayas3    NT, R.B.4    Czeisler, C.A.5    Shea, J.A.6
  • 46
    • 0024494277 scopus 로고
    • Effects of melatonin on neuronal activity in the rat suprachiasmatic nucleus invitro
    • Shibata S, Cassone VM, Moore RY. Effects of melatonin on neuronal activity in the rat suprachiasmatic nucleus invitro. Neurosci. Lett. 97(1-2), 140-144 (1989).
    • (1989) Neurosci. Lett , vol.97 , Issue.1-2 , pp. 140-144
    • Shibata, S.1    Cassone, V.M.2    Moore, R.Y.3
  • 47
    • 4744369413 scopus 로고    scopus 로고
    • Sleep propensity of modulated by circadian and behavior-induced changes in cutaneous temperature
    • Van Someren EJ. Sleep propensity of modulated by circadian and behavior-induced changes in cutaneous temperature. J. Therm. Biol. 29, 437-444 (2004).
    • (2004) J. Therm. Biol , vol.29 , pp. 437-444
    • Van Someren, E.J.1
  • 48
    • 0031666310 scopus 로고    scopus 로고
    • Changes in sleepiness and body temperature precede nocturnal sleep onset: Evidence from a polysomnography study in young men
    • van den Heuvel C, Noone J, Lushington K, Dawson D. Changes in sleepiness and body temperature precede nocturnal sleep onset: evidence from a polysomnography study in young men. J. Sleep Res. 7, 159-166 (1998).
    • (1998) J. Sleep Res , vol.7 , pp. 159-166
    • van den Heuvel, C.1    Noone, J.2    Lushington, K.3    Dawson, D.4
  • 50
    • 0343527709 scopus 로고    scopus 로고
    • Warm feet promote the rapid onset of sleep
    • Krauchi K, Cajochen C, Werth E, Wirz-Justice A. Warm feet promote the rapid onset of sleep. Nature 401(6748), 36-37 (1999).
    • (1999) Nature , vol.401 , Issue.6748 , pp. 36-37
    • Krauchi, K.1    Cajochen, C.2    Werth, E.3    Wirz-Justice, A.4
  • 52
    • 0033049908 scopus 로고    scopus 로고
    • Thermoregulatory and soporific effects of very low dose melatonin injection
    • van den Heuvel C, Kennaway D, Dawson D. Thermoregulatory and soporific effects of very low dose melatonin injection. Am. J. Physiol. 276, E249-E254 (1999).
    • (1999) Am. J. Physiol , vol.276
    • van den Heuvel, C.1    Kennaway, D.2    Dawson, D.3
  • 53
    • 0033082096 scopus 로고    scopus 로고
    • Daytime melatonin and tempazepam in young adult humans: Equivalent effects on sleep latency and body temperature
    • Gilbert S, van den Heuvel C, Dawson D. Daytime melatonin and tempazepam in young adult humans: equivalent effects on sleep latency and body temperature. J. Physiol. 514(3), 905-914 (1999).
    • (1999) J. Physiol , vol.514 , Issue.3 , pp. 905-914
    • Gilbert, S.1    van den Heuvel, C.2    Dawson, D.3
  • 54
    • 0034045158 scopus 로고    scopus 로고
    • More than a marker: Interaction between the circadian regulation of temperature and sleep, age-related changes, and treatment possibilities
    • Van Someren EJ. More than a marker: interaction between the circadian regulation of temperature and sleep, age-related changes, and treatment possibilities. Chronobiol. Int. 17(3), 313-354 (2000).
    • (2000) Chronobiol. Int , vol.17 , Issue.3 , pp. 313-354
    • Van Someren, E.J.1
  • 55
    • 65649123794 scopus 로고    scopus 로고
    • Melatonin and melatonergic drugs on sleep: Possible mechanisms of action
    • Srinivasan V, Pandi-Perumal SR, Trahkt I et al. Melatonin and melatonergic drugs on sleep: Possible mechanisms of action. Int. J. Neurosci. 119(6), 821-846 (2009).
    • (2009) Int. J. Neurosci , vol.119 , Issue.6 , pp. 821-846
    • Srinivasan, V.1    Pandi-Perumal, S.R.2    Trahkt, I.3
  • 57
    • 58249084605 scopus 로고    scopus 로고
    • A practical approach to circadian rhythm sleep disorders
    • Bjorvatn B, Pallesen S. A practical approach to circadian rhythm sleep disorders. Sleep Med. Rev. 13, 47-60 (2009).
    • (2009) Sleep Med. Rev , vol.13 , pp. 47-60
    • Bjorvatn, B.1    Pallesen, S.2
  • 58
    • 53949107676 scopus 로고    scopus 로고
    • Melatonin and its agonists: An update
    • Arendt J, Rajaratnam SMW. Melatonin and its agonists: an update. Br. J. Psychiatry 193, 267-269 (2008).
    • (2008) Br. J. Psychiatry , vol.193 , pp. 267-269
    • Arendt, J.1    Rajaratnam, S.M.W.2
  • 59
    • 0033004393 scopus 로고    scopus 로고
    • Peripheral heat loss: A predictor of the hypothermic response to melatonin administration in young and older women
    • Gilbert S, van den Heuvel C, Kennaway D, Dawson D. Peripheral heat loss: a predictor of the hypothermic response to melatonin administration in young and older women. Physiol. Behav. 66(2), 365-370 (1999).
    • (1999) Physiol. Behav , vol.66 , Issue.2 , pp. 365-370
    • Gilbert, S.1    van den Heuvel, C.2    Kennaway, D.3    Dawson, D.4
  • 60
    • 0032238871 scopus 로고    scopus 로고
    • Effect of sustained nocturnal transbuccal melatonin administration on sleep and temperature in elderly insomniacs
    • Dawson D, Rogers N, van den Heuvel CJ, Kennaway DJ, Lushington K. Effect of sustained nocturnal transbuccal melatonin administration on sleep and temperature in elderly insomniacs. J. Biol. Rhythms 13(6), 532-538 (1998).
    • (1998) J. Biol. Rhythms , vol.13 , Issue.6 , pp. 532-538
    • Dawson, D.1    Rogers, N.2    van den Heuvel, C.J.3    Kennaway, D.J.4    Lushington, K.5
  • 61
    • 0028990931 scopus 로고
    • Improvement of sleep quality in elderly people by controlled-release melatonin
    • Garfinkel D, Laudon M, Nof D, Zisapel N. Improvement of sleep quality in elderly people by controlled-release melatonin. Lancet 346(8974), 541-544 (1995).
    • (1995) Lancet , vol.346 , Issue.8974 , pp. 541-544
    • Garfinkel, D.1    Laudon, M.2    Nof, D.3    Zisapel, N.4
  • 62
    • 52949138639 scopus 로고    scopus 로고
    • Effects of prolonged-release melatonin, zolpidem, and their combination on psychomotor functions, memory recall, and driving skills in healthy middle aged and elderly volunteers
    • Otmani S, Demazieres A, Staner C et al. Effects of prolonged-release melatonin, zolpidem, and their combination on psychomotor functions, memory recall, and driving skills in healthy middle aged and elderly volunteers. Hum. Psychopharmacol. 23(8), 693-705 (2008).
    • (2008) Hum. Psychopharmacol , vol.23 , Issue.8 , pp. 693-705
    • Otmani, S.1    Demazieres, A.2    Staner, C.3
  • 63
    • 0023201917 scopus 로고    scopus 로고
    • Strogatz SH, Kronauer RE, Czeisler CA. Circadian pacemaker interferes with sleep onset at specific times each day: role in insomnia. Am. J. Physiol. 252(1Pt2), R172-R178 (1987).
    • Strogatz SH, Kronauer RE, Czeisler CA. Circadian pacemaker interferes with sleep onset at specific times each day: role in insomnia. Am. J. Physiol. 252(1Pt2), R172-R178 (1987).
  • 64
    • 0022640123 scopus 로고
    • Ultrashort sleep-waking schedule. III. 'Gates' and 'forbidden zones' for sleep
    • Lavie P. Ultrashort sleep-waking schedule. III. 'Gates' and 'forbidden zones' for sleep. Electroencephalogr. Clin. Neurophysiol. 63, 414-425 (1986).
    • (1986) Electroencephalogr. Clin. Neurophysiol , vol.63 , pp. 414-425
    • Lavie, P.1
  • 65
    • 9344242983 scopus 로고    scopus 로고
    • Melatonin advances the circadian timing of EEG sleep and directly facilitates sleep without altering its duration in extended sleep opportunties in humans
    • Rajaratnam SMW, Middleton B, Stone BM, Arendt J, Dijk D. Melatonin advances the circadian timing of EEG sleep and directly facilitates sleep without altering its duration in extended sleep opportunties in humans. J. Physiol. 561(Pt1), 339-351 (2004).
    • (2004) J. Physiol , vol.561 , Issue.PT1 , pp. 339-351
    • Rajaratnam, S.M.W.1    Middleton, B.2    Stone, B.M.3    Arendt, J.4    Dijk, D.5
  • 66
    • 33646746401 scopus 로고    scopus 로고
    • Sleep-faciltating effect of exogenous melatonin in healthy young men and women is circadian-phase dependent
    • Wyatt JK, Dijk DJ, Ritz-de Cecco A, Ronda JM, Czeisler CA. Sleep-faciltating effect of exogenous melatonin in healthy young men and women is circadian-phase dependent. Sleep 29(5), 609-618 (2006).
    • (2006) Sleep , vol.29 , Issue.5 , pp. 609-618
    • Wyatt, J.K.1    Dijk, D.J.2    Ritz-de Cecco, A.3    Ronda, J.M.4    Czeisler, C.A.5
  • 67
    • 33644869714 scopus 로고    scopus 로고
    • Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restricton: A meta-analysis
    • Buscemi N, Vandermeer B, Hooton N et al. Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restricton: a meta-analysis. Br. Med. J. 332(7538), 385-393 (2006).
    • (2006) Br. Med. J , vol.332 , Issue.7538 , pp. 385-393
    • Buscemi, N.1    Vandermeer, B.2    Hooton, N.3
  • 68
    • 0036051470 scopus 로고    scopus 로고
    • Herxheimer A, Petrie KJ. Melatonin for the prevention and treatment of jet lag (Cochrane Review). Cochrance Database Syst. Rev. 2, CD001520 (2002).
    • Herxheimer A, Petrie KJ. Melatonin for the prevention and treatment of jet lag (Cochrane Review). Cochrance Database Syst. Rev. 2, CD001520 (2002).
  • 69
    • 30944449193 scopus 로고    scopus 로고
    • The efficacy and safety of exogenous melatonin for primary sleep disorders: A meta-analysis
    • Buscemi N, Vandermeer B, Hooton N et al. The efficacy and safety of exogenous melatonin for primary sleep disorders: a meta-analysis. J. Gen. Int. Med. 20(12), 1151-1158 (2005).
    • (2005) J. Gen. Int. Med , vol.20 , Issue.12 , pp. 1151-1158
    • Buscemi, N.1    Vandermeer, B.2    Hooton, N.3
  • 70
    • 7044263197 scopus 로고    scopus 로고
    • Melatonin, sleep, and circadian rhythms: Rationale for development of specific melatonin agonists
    • Turek FW, Gillette MU. Melatonin, sleep, and circadian rhythms: rationale for development of specific melatonin agonists. Sleep Med. 5, 523-532 (2004).
    • (2004) Sleep Med , vol.5 , pp. 523-532
    • Turek, F.W.1    Gillette, M.U.2
  • 71
    • 0030914787 scopus 로고    scopus 로고
    • Effect of atenolol on nocturnal sleep and temperature in young men: Reversal by pharmacological doses of melatonin
    • van den Heuvel CJ, Reid KJ, Dawson D. Effect of atenolol on nocturnal sleep and temperature in young men: reversal by pharmacological doses of melatonin. Physiol. Behav. 61(6), 795-802 (1997).
    • (1997) Physiol. Behav , vol.61 , Issue.6 , pp. 795-802
    • van den Heuvel, C.J.1    Reid, K.J.2    Dawson, D.3
  • 72
    • 12244294179 scopus 로고    scopus 로고
    • The sleep-promoting action of ramelteon (TAK-375) in freely moving cats
    • Miyamoto M, Nishikawa H, Doken Y, Hirai K, Uchikawa O, Ohkawa S. The sleep-promoting action of ramelteon (TAK-375) in freely moving cats. Sleep 27(7), 1319-1325 (2004).
    • (2004) Sleep , vol.27 , Issue.7 , pp. 1319-1325
    • Miyamoto, M.1    Nishikawa, H.2    Doken, Y.3    Hirai, K.4    Uchikawa, O.5    Ohkawa, S.6
  • 73
  • 74
    • 67649418003 scopus 로고    scopus 로고
    • Influence of the novel antidepressant and melatonin agonist/serotonin2C receptor antagonist, agomelatine, on the rat sleep-wake cycle architecture
    • Descamps A, Rousset C, Millan MJ, Spedding M, Delagrange P, Cespuglio R. Influence of the novel antidepressant and melatonin agonist/serotonin2C receptor antagonist, agomelatine, on the rat sleep-wake cycle architecture. Psychopharmacology 205(1), 93-106 (2009).
    • (2009) Psychopharmacology , vol.205 , Issue.1 , pp. 93-106
    • Descamps, A.1    Rousset, C.2    Millan, M.J.3    Spedding, M.4    Delagrange, P.5    Cespuglio, R.6
  • 75
    • 14644426021 scopus 로고    scopus 로고
    • Ramelteon (TAK-375), a selective MT1/MT2-receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment
    • Roth T, Stubbs C, Wash JK. Ramelteon (TAK-375), a selective MT1/MT2-receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment. Sleep 28(3), 303-307 (2005).
    • (2005) Sleep , vol.28 , Issue.3 , pp. 303-307
    • Roth, T.1    Stubbs, C.2    Wash, J.K.3
  • 77
    • 20344399217 scopus 로고    scopus 로고
    • Winkelman J, Kotagal S, Olson E, Scammel T, Schenck C, Spielman A Eds, 2nd Edition, American Academy of Sleep Medicine, IL, USA
    • Winkelman J, Kotagal S, Olson E, Scammel T, Schenck C, Spielman A (Eds). The International Classification of Sleep Disorders: Diagnostic and Coding Manual (2nd Edition). American Academy of Sleep Medicine, IL, USA (2005).
    • (2005) The International Classification of Sleep Disorders: Diagnostic and Coding Manual
  • 78
    • 0026217050 scopus 로고
    • Melatonin administration to blind people: Phase advances and entrainment
    • Sack RL, Lewy AJ, Blood ML, Stevenson J, Keith LD. Melatonin administration to blind people: phase advances and entrainment. J. Biol. Rhythms 6(3), 249-261 (1991).
    • (1991) J. Biol. Rhythms , vol.6 , Issue.3 , pp. 249-261
    • Sack, R.L.1    Lewy, A.J.2    Blood, M.L.3    Stevenson, J.4    Keith, L.D.5
  • 79
    • 0025331377 scopus 로고
    • Melatonin stabilises sleep onset time in a blind man without entrainment of cortisol or temperature rhythms
    • Folkard S, Arendt J, Aldhous M, Kennett H. Melatonin stabilises sleep onset time in a blind man without entrainment of cortisol or temperature rhythms. Neurosci. Lett. 113(2), 193-198 (1990).
    • (1990) Neurosci. Lett , vol.113 , Issue.2 , pp. 193-198
    • Folkard, S.1    Arendt, J.2    Aldhous, M.3    Kennett, H.4
  • 80
    • 0034840010 scopus 로고    scopus 로고
    • Effects of melatonin administration on daytime sleep after simulated night shift work
    • Sharkey KM, Fogg LF, Eastman CI. Effects of melatonin administration on daytime sleep after simulated night shift work. J. Sleep Res. 10(3), 181-192 (2001).
    • (2001) J. Sleep Res , vol.10 , Issue.3 , pp. 181-192
    • Sharkey, K.M.1    Fogg, L.F.2    Eastman, C.I.3
  • 82
  • 83
    • 0031817812 scopus 로고    scopus 로고
    • Delayed sleep phase syndrome: A placebo-controlled cross-over study on the effects of melatonin administered five hours before the individual dim light melatonin onset
    • Nagtegall JE, Kerkhof GA, Smits MG, Swart AC, Van Der Meer YG. Delayed sleep phase syndrome: A placebo-controlled cross-over study on the effects of melatonin administered five hours before the individual dim light melatonin onset. J. Sleep Res. 7(2), 135-143 (1998).
    • (1998) J. Sleep Res , vol.7 , Issue.2 , pp. 135-143
    • Nagtegall, J.E.1    Kerkhof, G.A.2    Smits, M.G.3    Swart, A.C.4    Van Der Meer, Y.G.5
  • 84
    • 0031786860 scopus 로고    scopus 로고
    • Comparitive study to determine the optimal melatonin dosage form for the alleviation of jet lag
    • Suhner A, Schlagenhauf P, Johnson R, Tschopp A, Steffen R. Comparitive study to determine the optimal melatonin dosage form for the alleviation of jet lag. Chronobiol. Int. 15(6), 655-666 (1998).
    • (1998) Chronobiol. Int , vol.15 , Issue.6 , pp. 655-666
    • Suhner, A.1    Schlagenhauf, P.2    Johnson, R.3    Tschopp, A.4    Steffen, R.5
  • 85
    • 0035140797 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled crossover study of the effect of exogenous melatonin on delayed sleep phase syndrome
    • Kayumov L, Brown G, Jindal R, Buttoo K, Shapiro CM. A randomized, double-blind, placebo-controlled crossover study of the effect of exogenous melatonin on delayed sleep phase syndrome. Psychosom. Med. 63(1), 40-48 (2001).
    • (2001) Psychosom. Med , vol.63 , Issue.1 , pp. 40-48
    • Kayumov, L.1    Brown, G.2    Jindal, R.3    Buttoo, K.4    Shapiro, C.M.5
  • 86
    • 33644895410 scopus 로고    scopus 로고
    • Does melatonin improve sleep? Efficacy of melatonin
    • Arendt J. Does melatonin improve sleep? Efficacy of melatonin. Br. Med. J. 332(7540), 550 (2006).
    • (2006) Br. Med. J , vol.332 , Issue.7540 , pp. 550
    • Arendt, J.1
  • 87
    • 0022622356 scopus 로고
    • Alleviation of jet lag by melatonin: Preliminary results of controlled double blind trial
    • Arendt J, Aldhous M, Marks V. Alleviation of jet lag by melatonin: preliminary results of controlled double blind trial. Br. Med. J. 292(6529), 1170 (1986).
    • (1986) Br. Med. J , vol.292 , Issue.6529 , pp. 1170
    • Arendt, J.1    Aldhous, M.2    Marks, V.3
  • 88
    • 0031966325 scopus 로고    scopus 로고
    • Evaluating the role of melatonin in the long-term treatment of delayed sleep phase syndrome (DSPS)
    • Dagan Y, Yovel I, Hallis D, Eisenstein M, Raichik I. Evaluating the role of melatonin in the long-term treatment of delayed sleep phase syndrome (DSPS). Chronobiol. Int. 15(2), 181-190 (1998).
    • (1998) Chronobiol. Int , vol.15 , Issue.2 , pp. 181-190
    • Dagan, Y.1    Yovel, I.2    Hallis, D.3    Eisenstein, M.4    Raichik, I.5
  • 89
    • 0033986476 scopus 로고    scopus 로고
    • Melatonin administration can entrain the free-running circadian system of blind subjects
    • Lockley SW, Skene DJ, James K, Thapan K, Wright J, Arendt J. Melatonin administration can entrain the free-running circadian system of blind subjects. J. Endocrinol. 164(1), R1-R6 (2000).
    • (2000) J. Endocrinol , vol.164 , Issue.1
    • Lockley, S.W.1    Skene, D.J.2    James, K.3    Thapan, K.4    Wright, J.5    Arendt, J.6
  • 90
    • 0034642063 scopus 로고    scopus 로고
    • Entrainment of free-running circadian rhythms by melatonin in blind people
    • Sack RL, Brandes RW, Kendall AR, LewyAJ. Entrainment of free-running circadian rhythms by melatonin in blind people. N. Engl. J. Med. 343(15), 1070-1077 (2000).
    • (2000) N. Engl. J. Med , vol.343 , Issue.15 , pp. 1070-1077
    • Sack, R.L.1    Brandes, R.W.2    Kendall, A.R.3    LewyAJ4
  • 93
    • 0028895201 scopus 로고
    • Improvement of sleep quality by melatonin
    • Wurtman RJ, Zhdanova IV. Improvement of sleep quality by melatonin. Lancet 346(8988), 1491 (1995).
    • (1995) Lancet , vol.346 , Issue.8988 , pp. 1491
    • Wurtman, R.J.1    Zhdanova, I.V.2
  • 94
    • 0031886418 scopus 로고    scopus 로고
    • The role of melatonin and circadain phase in age-related sleep-maintenance insomnia: Assessment in a clinical trial of melatonin replacement
    • Hughes RJ, Sack RL, Lewy AJ. The role of melatonin and circadain phase in age-related sleep-maintenance insomnia: assessment in a clinical trial of melatonin replacement. Sleep 21(1), 52-68 (1998).
    • (1998) Sleep , vol.21 , Issue.1 , pp. 52-68
    • Hughes, R.J.1    Sack, R.L.2    Lewy, A.J.3
  • 96
    • 36349021288 scopus 로고    scopus 로고
    • Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects
    • Lemoine P, Nir T, Laudon M, Zisapel N. Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects. J. Sleep Res. 16(4), 372-380 (2007).
    • (2007) J. Sleep Res , vol.16 , Issue.4 , pp. 372-380
    • Lemoine, P.1    Nir, T.2    Laudon, M.3    Zisapel, N.4
  • 97
    • 46049106523 scopus 로고    scopus 로고
    • Efficacy and clinical safety of ramelteon: An evidence-based review
    • Sateia MJ, Kirby-Long P, Taylor JL. Efficacy and clinical safety of ramelteon: an evidence-based review. Sleep Med. Rev. 12, 319-332 (2008).
    • (2008) Sleep Med. Rev , vol.12 , pp. 319-332
    • Sateia, M.J.1    Kirby-Long, P.2    Taylor, J.L.3
  • 98
    • 29844447353 scopus 로고    scopus 로고
    • An efficacy, safety, and dose-response study of ramelteon in patients with chronic primary insomnia
    • Erman M, Seiden D, Zammit G, Sainati S, Zhang J. An efficacy, safety, and dose-response study of ramelteon in patients with chronic primary insomnia. Sleep Med. 7, 17-24 (2006).
    • (2006) Sleep Med , vol.7 , pp. 17-24
    • Erman, M.1    Seiden, D.2    Zammit, G.3    Sainati, S.4    Zhang, J.5
  • 99
    • 33646925615 scopus 로고    scopus 로고
    • Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia
    • Roth T, Seiden D, Sainati S, Wang-Weigand S, Zhang J, Zee P. Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia. Sleep Med. 7(4), 312-318 (2006).
    • (2006) Sleep Med , vol.7 , Issue.4 , pp. 312-318
    • Roth, T.1    Seiden, D.2    Sainati, S.3    Wang-Weigand, S.4    Zhang, J.5    Zee, P.6
  • 100
    • 34249104541 scopus 로고    scopus 로고
    • A 2-night, 3-period, crossover study of ramelteon's efficacy and safety in older adults with chronic insomnia
    • Roth T, Seiden D, Wang-Weigand S, Zhang J. A 2-night, 3-period, crossover study of ramelteon's efficacy and safety in older adults with chronic insomnia. Curr. Med. Res. Opin. 23(5), 1005-1014 (2007).
    • (2007) Curr. Med. Res. Opin , vol.23 , Issue.5 , pp. 1005-1014
    • Roth, T.1    Seiden, D.2    Wang-Weigand, S.3    Zhang, J.4
  • 101
    • 35148863674 scopus 로고    scopus 로고
    • Efficacy and tolerability of indiplon in older adults with primary insomnia
    • Walsh JK, Moscovitch A, Burke J, FarberR, Roth T. Efficacy and tolerability of indiplon in older adults with primary insomnia. Sleep Med. 8(7-8), 753-759 (2007).
    • (2007) Sleep Med , vol.8 , Issue.7-8 , pp. 753-759
    • Walsh, J.K.1    Moscovitch, A.2    Burke, J.3    Farber, R.4    Roth, T.5
  • 102
    • 34249790867 scopus 로고    scopus 로고
    • Long-term nightly treatment with indiplon in adults with primary insomnia: Results of a double-blind, placebo-controlled, 3-month study
    • Scharf MB, Black J, Hull S, Landin R, Farber R. Long-term nightly treatment with indiplon in adults with primary insomnia: results of a double-blind, placebo-controlled, 3-month study. Sleep 30(6), 743-752 (2007).
    • (2007) Sleep , vol.30 , Issue.6 , pp. 743-752
    • Scharf, M.B.1    Black, J.2    Hull, S.3    Landin, R.4    Farber, R.5
  • 103
    • 41549115007 scopus 로고    scopus 로고
    • A review of ramelteon in the treatment of sleep disorders
    • Neubauer DN. A review of ramelteon in the treatment of sleep disorders. Neuropsychiatr. Dis. Treat. 4(1), 69-79 (2008).
    • (2008) Neuropsychiatr. Dis. Treat , vol.4 , Issue.1 , pp. 69-79
    • Neubauer, D.N.1
  • 104
    • 33749390304 scopus 로고    scopus 로고
    • Ramelteon: A novel hypnotic lacking abuse liability and sedative adverse effects
    • Johnson MW, Suess PE, Griffiths RR. Ramelteon: a novel hypnotic lacking abuse liability and sedative adverse effects. Arch. Gen. Psychiatry 63(10), 1149-1157 (2006).
    • (2006) Arch. Gen. Psychiatry , vol.63 , Issue.10 , pp. 1149-1157
    • Johnson, M.W.1    Suess, P.E.2    Griffiths, R.R.3
  • 107
    • 0031870926 scopus 로고    scopus 로고
    • Melatonin for the treatment of sleep disturbances in major depressive disorder
    • Dolberg OT, Hirschmann S, Grunhaus L. Melatonin for the treatment of sleep disturbances in major depressive disorder. Am. J. Psychiatry 155(8), 1119-1121 (1998).
    • (1998) Am. J. Psychiatry , vol.155 , Issue.8 , pp. 1119-1121
    • Dolberg, O.T.1    Hirschmann, S.2    Grunhaus, L.3
  • 108
    • 2342459611 scopus 로고    scopus 로고
    • Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: Involvement of melatonin and serotonin receptors
    • Bourin M, Mocaer E, Porsolt R. Antidepressant-like activity of S 20098 (agomelatine) in the forced swimming test in rodents: involvement of melatonin and serotonin receptors. J. Psychiatry Neurosci. 29(2), 126-133 (2004).
    • (2004) J. Psychiatry Neurosci , vol.29 , Issue.2 , pp. 126-133
    • Bourin, M.1    Mocaer, E.2    Porsolt, R.3
  • 110
    • 0036738228 scopus 로고    scopus 로고
    • Determination of the dose of agoemlatine, a melatonergic agonist and selective 5HT-(2C) antagonist, in the treatment of major depressive disorder: A placebo-controlled dose range study
    • Loo H, Hale A, D'Haenen H. Determination of the dose of agoemlatine, a melatonergic agonist and selective 5HT-(2C) antagonist, in the treatment of major depressive disorder: a placebo-controlled dose range study. Int. Clin. Psychopharmacol. 17(5), 239-247 (2002).
    • (2002) Int. Clin. Psychopharmacol , vol.17 , Issue.5 , pp. 239-247
    • Loo, H.1    Hale, A.2    D'Haenen, H.3
  • 111
    • 31344471423 scopus 로고    scopus 로고
    • Placebo-controlled trial of agomelatine in the treatment of major depressive disorder
    • Kennedy SH, Emsley R. Placebo-controlled trial of agomelatine in the treatment of major depressive disorder. Eur. Neuropsychpharmacol. 16(2), 93-100 (2006).
    • (2006) Eur. Neuropsychpharmacol , vol.16 , Issue.2 , pp. 93-100
    • Kennedy, S.H.1    Emsley, R.2
  • 112
    • 33646712414 scopus 로고    scopus 로고
    • Confirmed clinical efficacy of agomelatinin (25-50mg) in major depression: Two randomized, doubel-blind placebo controlled studies
    • S
    • Olie JP, Emsley R. Confirmed clinical efficacy of agomelatinin (25-50mg) in major depression: two randomized, doubel-blind placebo controlled studies. Eur. Neuropsychpharmacol. 15(Suppl. 3), S416 (2005).
    • (2005) Eur. Neuropsychpharmacol , vol.15 , Issue.SUPPL. 3 , pp. 416
    • Olie, J.P.1    Emsley, R.2
  • 113
    • 37049039648 scopus 로고    scopus 로고
    • Improvement in subjective sleep in major depressive disorder with a novel antidperessant, agomelatine: Randomised, double-blind comparison with venlafaxine
    • Lemoine P, Guilleminault C, Alvarez E. Improvement in subjective sleep in major depressive disorder with a novel antidperessant, agomelatine: Randomised, double-blind comparison with venlafaxine. J. Clin. Psychiatry, 68(11), 1723-1732 (2007).
    • (2007) J. Clin. Psychiatry , vol.68 , Issue.11 , pp. 1723-1732
    • Lemoine, P.1    Guilleminault, C.2    Alvarez, E.3
  • 114
    • 51449124059 scopus 로고    scopus 로고
    • Agomelatine: A novel mechanism of antidepressant action involving the melatonergic and the serotonergic system
    • San L, Arranz B. Agomelatine: a novel mechanism of antidepressant action involving the melatonergic and the serotonergic system. Eur. Psychiatry 23, 396-402 (2008).
    • (2008) Eur. Psychiatry , vol.23 , pp. 396-402
    • San, L.1    Arranz, B.2
  • 115
    • 33646686569 scopus 로고    scopus 로고
    • Efficacy and tolerance profile of agomelatine and practical use in depressed patients
    • Rouillon F. Efficacy and tolerance profile of agomelatine and practical use in depressed patients. Int. Clin. Psychopharmacol. 21(Suppl. 1) S31-S35 (2006).
    • (2006) Int. Clin. Psychopharmacol , vol.21 , Issue.SUPPL. 1
    • Rouillon, F.1
  • 116
    • 33745386856 scopus 로고    scopus 로고
    • Early evening melatonin and S-20098 advance circadian phase and nocturnal regulation of core body temperature
    • Kräuchi K , Cajochen C, Möri D, Graw P, Wirz-Justice A. Early evening melatonin and S-20098 advance circadian phase and nocturnal regulation of core body temperature. Am. J. Physiol. 272(4 Pt 2), R1178-R1188 (1997).
    • (1997) Am. J. Physiol , vol.272 , Issue.4 PART 2
    • Kräuchi, K.1    Cajochen, C.2    Möri, D.3    Graw, P.4    Wirz-Justice, A.5
  • 117
    • 0038050606 scopus 로고    scopus 로고
    • Effect of agomelatine in the chronic mild stress model of depression in the rat
    • Papp M, Gruca P, Boyer PA, Mocaer E. Effect of agomelatine in the chronic mild stress model of depression in the rat. Neuropsychopharmacology 28(4), 694-703 (2003).
    • (2003) Neuropsychopharmacology , vol.28 , Issue.4 , pp. 694-703
    • Papp, M.1    Gruca, P.2    Boyer, P.A.3    Mocaer, E.4
  • 118
    • 34948878022 scopus 로고    scopus 로고
    • Major depressive disorder, sleep EEG and agomelatine: An open-label study
    • Quera-Salva MA, Vanier B, Laredo J et al. Major depressive disorder, sleep EEG and agomelatine: an open-label study. Int. J. Neuropsychopharmacol. 10(5), 691-696 (2007).
    • (2007) Int. J. Neuropsychopharmacol , vol.10 , Issue.5 , pp. 691-696
    • Quera-Salva, M.A.1    Vanier, B.2    Laredo, J.3
  • 119
    • 76249114489 scopus 로고    scopus 로고
    • chemBlinkwww.chemblink.com


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.