Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs

Neuroscience

Volumn 133, Issue 4, 2005, Pages 983-997

  Abrams, J K ^a   Johnson, P L ^a   Hay Schmidt, A ^b   Mikkelsen, J D ^b,c   Shekhar, A ^d   Lowry, C A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c NEUROSEARCH A S   (Denmark)

^d INDIANA UNIVERSITY   (United States)

Author keywords

Anxiety; Basolateral amygdala; c Fos; Dorsal raphe nucleus; Retrograde tracing; Serotonin

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; CAFFEINE; N METHYL BETA CARBOLINE 3 CARBOXAMIDE; PROTEIN C FOS; SEROTONIN 2A ANTAGONIST; YOHIMBINE;

ALERTNESS; AMYGDALOID NUCLEUS; ANIMAL MODEL; ANXIETY; AROUSAL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; DRUG EFFECT; FOREBRAIN; IMMUNOHISTOCHEMISTRY; MALE; MOTOR CONTROL; MOTOR SYSTEM; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEROTONINERGIC SYSTEM; TOPOGRAPHY;

ADRENERGIC ALPHA-ANTAGONISTS; ANALYSIS OF VARIANCE; ANIMALS; ANTI-ANXIETY AGENTS; AROUSAL; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BRAIN; BRAIN MAPPING; CAFFEINE; CARBOLINES; CELL COUNT; CENTRAL NERVOUS SYSTEM STIMULANTS; FEEDING BEHAVIOR; GABA ANTAGONISTS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MALE; NEURAL PATHWAYS; NEURONS; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-FOS; RAPHE NUCLEI; RATS; RATS, WISTAR; SEROTONIN; SEROTONIN AGONISTS; STILBAMIDINES; TIME FACTORS; TRYPTOPHAN HYDROXYLASE; VIDEO RECORDING; YOHIMBINE;

EID: 20444450115     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2005.03.025     Document Type: Article

References (67)

1. J.K. Abrams, P.L. Johnson, J.H. Hollis, C.A. Lowry Anatomic and functional topography of the dorsal raphe nucleus Ann N Y Acad Sci 1018 2004 46 57
2. R.E. Adamec Evidence that long-lasting potentiation in limbic circuits mediating defensive behaviour in the right hemisphere underlies pharmacological stressor (FG-7142) induced lasting increases in anxiety-like behaviour role of benzodiazepine receptors J Psychopharmacol 14 2000 307 322
3. J. Amat, P. Matus-Amat, L.R. Watkins, S.F. Maier Escapable and inescapable stress differentially alter extracellular levels of 5-HT in the basolateral amygdala of the rat Brain Res 812 1998 113 120
4. J.M. Arthur, S.J. Casanas, J.R. Raymond Partial agonist properties of rauwolscine and yohimbine for the inhibition of adenylyl cyclase by recombinant human 5-HT1A receptors Biochem Pharmacol 45 1993 2337 2341
5. C.S. Aulakh, K.M. Wozniak, J.L. Hill, C.L. Devane, T.J. Tolliver, D.L. Murphy Differential neuroendocrine responses to the 5-HT agonist m-chlorophenylpiperazine in Fawn-Hooded rats relative to Wistar and Sprague-Dawley rats Neuroendocrinology 48 1988 401 406
6. R.J. Blanchard, D.C. Blanchard Attack and defense in rodents as ethoexperimental models for the study of emotion Prog Neuropsychopharmacol Biol Psychiatry 13 Suppl 1989 S3 S14
7. P.D. Butler, J.M. Weiss, J.C. Stout, C.B. Nemeroff Corticotropin- releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus coeruleus J Neurosci 10 1990 176 183
8. B.M. Campbell, K.M. Merchant Serotonin 2C receptors within the basolateral amygdala induce acute fear-like responses in an open-field environment Brain Res 993 2003 1 9
9. S. Ceccatelli, M.J. Villar, M. Goldstein, T. Hokfelt Expression of c-Fos immunoreactivity in transmitter-characterized neurons after stress Proc Natl Acad Sci USA 86 1989 9569 9573
10. F. Chamas, L. Serova, E.L. Sabban Tryptophan hydroxylase mRNA levels are elevated by repeated immobilization stress in rat raphe nuclei but not in pineal gland Neurosci Lett 267 1999 157 160
11. D.S. Charney, A. Deutch A functional neuroanatomy of anxiety and fear implications for the pathophysiology and treatment of anxiety disorders Crit Rev Neurobiol 10 1996 419 446
12. D.S. Charney, G.R. Heninger, D.E. Redmond Jr Yohimbine induced anxiety and increased noradrenergic function in humans effects of diazepam and clonidine Life Sci 33 1983 19 29
13. K.G. Commons, K.R. Connolley, R.J. Valentino A neurochemically distinct dorsal raphe-limbic circuit with a potential role in affective disorders Neuropsychopharmacology 28 2003 206 215
14. M.A. Critchley, K. Njung'e, S.L. Handley Actions and some interactions of 5-HT1A ligands in the elevated X-maze and effects of dorsal raphe lesions Psychopharmacology (Berl) 106 1992 484 490
15. M. Davis Are different parts of the extended amygdala involved in fear versus anxiety? Biol Psychiatry 44 1998 1239 1247
16. R. Dorow, R. Horowski, G. Paschelke, M. Amin Severe anxiety induced by FG 7142, a beta-carboline ligand for benzodiazepine receptors Lancet 2 1983 98 99
17. S. Erzegovesi, L. Martucci, M. Henin, L. Bellodi Low versus standard dose mCPP challenge in obsessive-compulsive patients Neuropsychopharmacology 24 2001 31 36
18. J.C. Gewirtz, K.A. McNish, M. Davis Lesions of the bed nucleus of the stria terminalis block sensitization of the acoustic startle reflex produced by repeated stress, but not fear-potentiated startle Prog Neuropsychopharmacol Biol Psychiatry 22 1998 625 648
19. L.E. Gonzalez, N. Andrews, S.E. File 5-HT1A and benzodiazepine receptors in the basolateral amygdala modulate anxiety in the social interaction test, but not in the elevated plus-maze Brain Res 732 1996 145 153
20. F.G. Graeff, F.S. Guimaraes, T.G. De Andrade, J.F. Deakin Role of 5-HT in stress, anxiety, and depression Pharmacol Biochem Behav 54 1996 129 141
21. F.G. Graeff, C.F. Netto, H. Zangrossi Jr The elevated T-maze as an experimental model of anxiety Neurosci Biobehav Rev 23 1998 237 246
22. F.G. Graeff, M.B. Viana, P.O. Mora Opposed regulation by dorsal raphe nucleus 5-HT pathways of two types of fear in the elevated T-maze Pharmacol Biochem Behav 53 1996 171 177
23. R.E. Grahn, M.J. Will, S.E. Hammack, S. Maswood, M.B. McQueen, L.R. Watkins, S.F. Maier Activation of serotonin-immunoreactive cells in the dorsal raphe nucleus in rats exposed to an uncontrollable stressor Brain Res 826 1999 35 43
24. H.J. Groenewegen, S. Ahlenius, S.N. Haber, N.W. Kowall, W.J. Nauta Cytoarchitecture, fiber connections, and some histochemical aspects of the interpeduncular nucleus in the rat J Comp Neurol 249 1986 65 102
25. S.E. Hammack, K.J. Richey, M.J. Schmid, M.L. LoPresti, L.R. Watkins, S.F. Maier The role of corticotropin-releasing hormone in the dorsal raphe nucleus in mediating the behavioral consequences of uncontrollable stress J Neurosci 22 2002 1020 1026
26. G.A. Higgins, B.J. Jones, N.R. Oakley Effect of 5-HT1A receptor agonists in two models of anxiety after dorsal raphe injection Psychopharmacology (Berl) 106 1992 261 267
27. H. Hodges, S. Green, B. Glenn Evidence that the amygdala is involved in benzodiazepine and serotonergic effects on punished responding but not on discrimination Psychopharmacology (Berl) 92 1987 491 504
28. H. Imai, D.A. Steindler, S.T. Kitai The organization of divergent axonal projections from the midbrain raphe nuclei in the rat J Comp Neurol 243 1986 363 380
29. Y. Ishida, H. Hashiguchi, R. Takeda, Y. Ishizuka, Y. Mitsuyama, H. Kannan, T. Nishimori, D. Nakahara Conditioned-fear stress increases Fos expression in monoaminergic and GABAergic neurons of the locus coeruleus and dorsal raphe nuclei Synapse 45 2002 46 51
30. B.L. Jacobs, E.C. Azmitia Structure and function of the brain serotonin system Physiol Rev 72 1992 165 229
31. T. Jolas, G.K. Aghajanian Opioids suppress spontaneous and NMDA-induced inhibitory postsynaptic currents in the dorsal raphe nucleus of the rat in vitro Brain Res 755 1997 229 245
32. K.A. Keay, R. Bandler Parallel circuits mediating distinct emotional coping reactions to different types of stress Neurosci Biobehav Rev 25 2001 669 678
33. A.E. Kelley Ventral striatal control of appetitive motivation role in ingestive behavior and reward-related learning Neurosci Biobehav Rev 27 2004 765 776
34. L.G. Kirby, K.C. Rice, R.J. Valentino Effects of corticotropin-releasing factor on neuronal activity in the serotonergic dorsal raphe nucleus Neuropsychopharmacology 22 2000 148 162
35. L. Levita, S.E. Hammack, I. Mania, X.Y. Li, M. Davis, D.G. Rainnie 5-Hydroxytryptamine1A-like receptor activation in the bed nucleus of the stria terminalis electrophysiological and behavioral studies Neuroscience 128 2004 583 596
36. A.S. Lin, T.W. Uhde, S.O. Slate, U.D. McCann Effects of intravenous caffeine administered to healthy males during sleep Depress Anxiety 5 1997 21 28
37. C.A. Lowry, J.E. Rodda, S.L. Lightman, C.D. Ingram Corticotropin- releasing factor increases in vitro firing rates of serotonergic neurons in the rat dorsal raphe nucleus evidence for activation of a topographically organized mesolimbocortical serotonergic system J Neurosci 20 2000 7728 7736
38. S.F. Maier, C.R. Busch, S. Maswood, R.E. Grahn, L.R. Watkins The dorsal raphe nucleus is a site of action mediating the behavioral effects of the benzodiazepine receptor inverse agonist DMCM Behav Neurosci 109 1995 759 766
39. S.F. Maier, R.E. Grahn, L.R. Watkins 8-OH-DPAT microinjected in the region of the dorsal raphe nucleus blocks and reverses the enhancement of fear conditioning and interference with escape produced by exposure to inescapable shock Behav Neurosci 109 1995 404 412
40. S.F. Maier, L.R. Watkins Stressor controllability, anxiety and serotonin Cogn Ther Res 22 1998 595 613
41. P. Martin, P. Bateson Measuring behaviour an introductory guide 1986 Cambridge University Press Cambridge
42. S. Matsuda, H. Peng, H. Yoshimura, T.C. Wen, T. Fukuda, M. Sakanaka Persistent c-fos expression in the brains of mice with chronic social stress Neurosci Res 26 1996 157 170
43. M.J. Millan The neurobiology and control of anxious states Prog Neurobiol 70 2003 83 244
44. T.R. Minor, M.K. Rowe, R.F. Soames Job, E.C. Ferguson Escape deficits induced by inescapable shock and metabolic stress are reversed by adenosine receptor antagonists Behav Brain Res 120 2001 203 212
45. M.E. Molliver Serotonergic neuronal systems what their anatomic organization tells us about function J Clin Psychopharmacol 7 1987 3S 23S
46. J.I. Morgan, T. Curran Stimulus-transcription coupling in neurons role of cellular immediate-early genes Trends Neurosci 12 1989 459 462
47. S.A. Nicholson Stimulatory effect of caffeine on the hypothalamo- pituitary-adrenocortical axis in the rat J Endocrinol 122 1989 535 543
48. G. Paxinos, C. Watson The rat brain in stereotaxic coordinates 4th edition 1998 Academic Press San Diego
49. S. Pellow, S.E. File The effects of putative anxiogenic compounds (FG 7142, CGS 8216 and Ro 15-1788) on the rat corticosterone response Physiol Behav 35 1985 587 590
50. R.G. Petersen Design and analysis of experiments 1985 Marcel Dekker, Inc New York 43 56
51. T. Petrov, T.L. Krukoff, J.H. Jhamandas The hypothalamic paraventricular and lateral parabrachial nuclei receive collaterals from raphe nucleus neurons a combined double retrograde and immunocytochemical study J Comp Neurol 318 1992 18 26
52. T. Petrov, T.L. Krukoff, J.H. Jhamandas Chemically defined collateral projections from the pons to the central nucleus of the amygdala and hypothalamic paraventricular nucleus in the rat Cell Tissue Res 277 1994 289 295
53. C. Peyron, J.M. Petit, C. Rampon, M. Jouvet, P.H. Luppi Forebrain afferents to the rat dorsal raphe nucleus demonstrated by retrograde and anterograde tracing methods Neuroscience 82 1998 443 468
54. D.G. Rainnie Serotonergic modulation of neurotransmission in the rat basolateral amygdala J Neurophysiol 82 1999 69 85
55. T.J. Sajdyk, A. Shekhar Excitatory amino acid receptors in the basolateral amygdala regulate anxiety responses in the social interaction test Brain Res 764 1997 262 264
56. S.K. Sanders, A. Shekhar Anxiolytic effects of chlordiazepoxide blocked by injection of GABAA and benzodiazepine receptor antagonists in the region of the anterior basolateral amygdala of rats Biol Psychiatry 37 1995 473 476
57. L.M. Sena, C. Bueno, R.L. Pobbe, T.G. Andrade, H. Zangrossi Jr, M.B. Viana The dorsal raphe nucleus exerts opposed control on generalized anxiety and panic-related defensive responses in rats Behav Brain Res 142 2003 125 133
58. N. Singewald, P. Salchner, T. Sharp Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs Biol Psychiatry 53 2003 275 283
59. N. Singewald, T. Sharp Neuroanatomical targets of anxiogenic drugs in the hindbrain as revealed by Fos immunocytochemistry Neuroscience 98 2000 759 770
60. H.W. Steinbusch Serotonin-immunoreactive neurons and their projections in the CNS A. Bjorklund T. Hokfelt Handbook of chemical neuroanatomy Vol. 3 1984 Elsevier New York 68 125
61. H.W. Steinbusch, R. Nieuwenhuys, A.A. Verhofstad, K.D. van der The nucleus raphe dorsalis of the rat and its projection upon the caudatoputamen A combined cytoarchitectonic, immunohistochemical and retrograde transport study. J Physiol (Paris) 77 1981 157 174
62. N.R. Swerdlow, F.J. Vaccarino, M. Amalric, G.F. Koob The neural substrates for the motor-activating properties of psychostimulants a review of recent findings Pharmacol Biochem Behav 25 1986 233 248
63. L.J. Teppema, J.G. Veening, A. Kranenburg, A. Dahan, A. Berkenbosch, C. Olievier Expression of c-fos in the rat brainstem after exposure to hypoxia and to normoxic and hyperoxic hypercapnia J Comp Neurol 388 1997 169 190
64. R.J. Valentino, L. Liouterman, E.J. Van Bockstaele Evidence for regional heterogeneity in corticotropin-releasing factor interactions in the dorsal raphe nucleus J Comp Neurol 435 2001 450 463
65. D.L. Walker, D.J. Toufexis, M. Davis Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety Eur J Pharmacol 463 2003 199 216
66. P. Whitton, G. Curzon Anxiogenic-like effect of infusing 1-(3-chlorophenyl) piperazine (mCPP) into the hippocampus Psychopharmacology (Berl) 100 1990 138 140
67. C.D. Wise, B.D. Berger, L. Stein Benzodiazepines anxiety-reducing activity by reduction of serotonin turnover in the brain Science 177 1972 180 183