Association between FTO 1st intron tagging variant and telomere length in middle aged females. 3PMFs study

Clinica Chimica Acta

Volumn 413, Issue 15-16, 2012, Pages 1222-1225

  Dlouha, D ^a   Pitha, J ^a   Lanska, V ^a   Hubacek, J A ^a  

^a INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

FTO gene; Polymorphism; Telomere length; Telomeres

Indexed keywords

ADULT; AGE DISTRIBUTION; ALLELE; ARTICLE; BODY MASS; BODY WEIGHT; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; CHROMOSOME SIZE; CLINICAL STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA SEQUENCE; EUKARYOTE; FEMALE; FTO GENE; GENE; GENE DOSAGE; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; INTRON; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MALIGNANT NEOPLASTIC DISEASE; MORTALITY; PRIORITY JOURNAL; SOMATIC CELL; SUBCUTANEOUS FAT; TELOMERE HOMEOSTASIS; WAIST CIRCUMFERENCE;

BODY MASS INDEX; FEMALE; GENE FREQUENCY; HUMANS; INTRONS; MENOPAUSE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; SUBCUTANEOUS FAT; TELOMERE;

EUKARYOTA;

EID: 84861335848     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2012.03.025     Document Type: Article

References (39)

1. Angelopoulos T.J., Lowndes J. ApoE genotype: impact on health, fitness and nutrition. World Rev Nutr Diet 2008, 98:77-93.
2. Poledne R., Hubacek J.A., Stanek V., et al. Why we are not able to find the coronary heart disease gene - apoE as an example. Fol Biol 2010, 56:218-222.
3. Hubacek J.A., Adamkova V., Vrablik M., et al. Apolipoprotein A5 in health and disease. Physiol Res 2009, 58:101-109.
4. Fawcett K.A., Barroso I. The genetics of obesity: FTO leads the way. Trends Genet 2010, 26:266-274.
5. Doney A.S., Dannfald J., Kimber C.H., et al. The FTO gene is associated with an atherogenic lipid profile and myocardial infarction in patients with type 2 diabetes: a Genetics of Diabetes Audit and Research Study in Tayside Scotland (Go-DARTS) study. Circ Cardiovasc Genet 2009, 2:255-259.
6. Hubacek J.A., Stanek V., Gebauerova M., et al. FTO variant and risk of acute coronary syndrome. Clin Chim Acta 2010, 411:1069-1072.
7. De Meyer T., Rietzschel E.R., De Buyzere M.L., et al. Telomere length and cardiovascular ageing: the means to the ends?. Ageing Res Rev 2011, 10:297-303.
8. Blackburn E.H. Switching and signaling at the telomere. Cell 2001, 106:661-673.
9. Saliques S., Zeller M., Lorin J., et al. Telomere length and cardiovascular disease. Arch Cardiovasc Dis 2010, 103:454-459.
10. Edo M.D., Andres V. Ageing, telomeres, and atherosclerosis. Cardiovasc Res 2005, 66:213-221.
11. Harley C.B., Futcher A.B., Greider C.W. Telomeres shorten during ageing of human fibroblasts. Nature 1990, 345:458-460.
12. Allsopp R.C., Vaziri H., Patterson C., et al. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci U S A 1992, 89:10114-10118.
13. Ishikawa N., Nakamura K.I., Izumiyama N., et al. Telomere length dynamics in the human pituitary gland: robust preservation throughout adult life to centenarian age. Age (Dordr) 2011, in press.
14. Wong L.S., van der Harst P., de Boer R.A., et al. Ageing, telomeres and heart failure. Heart Fail Rev 2010, 15:479-486.
15. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for DNA extraction from human nucleated cells. Nucleic Acid Res 1988, 16:1215.
16. Hubacek J.A., Bohuslavova R., Kuthanova L., et al. The FTO gene and obesity in a large Eastern European population sample: the HAPIEE study. Obesity 2008, 16:2764-2766.
17. Cawthon R.M. Telomere measurement by quantitative PCR. Nucleic Acids Res 2002, 30:e47.
18. Salpea K.D., Nicaud V., Tiret L., et al. The association of telomere length with paternal history of premature myocardial infarction in the European Atherosclerosis Research Study II. J Mol Med (Berl) 2008, 86:815-824.
19. Frayling T.M., Timpson N.J., Weedon M.N., et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007, 316:889-894.
20. Hubacek J.A., Pitha J., Adamkova V., et al. A common variant in the FTO gene is associated with body mass index in males and postmenopausal females but not in premenopausal females. Czech post-MONICA and 3PMFs studies. Clin Chem Lab Med 2009, 47:387-390.
21. Hubacek J.A., Pikhart H., Peasey A., et al. FTO variant, energy intake, physical activity and basal metabolic rate in Caucasians. The HAPIEE study. Physiol Res 2011, 60:175-183.
22. Lappalainen T., Kolehmainen M., Schwab U.S., et al. Finnish Diabetes Prevention Study Group. Association of the FTO gene variant (rs9939609) with cardiovascular disease in men with abnormal glucose metabolism - the Finnish Diabetes Prevention Study. Nutr Metab Cardiovasc Dis 2011, 21:691-698.
23. Brennan P., McKay J., Moore L., et al. Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype. Int J Epidemiol 2009, 38:971-975.
24. Nock N.L., Plummer S.J., Thompson C.L., et al. FTO polymorphisms are associated with adult body mass index (BMI) and colorectal adenomas in African-Americans. Carcinogenesis 2011, 32:748-756.
25. Scott L.J., Mohlke K.L., Bonnycastle L.L., et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007, 316:1341-1345.
26. Legry V., Cottel D., Ferrières J., et al. Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study. Metabolism 2009, 58:971-975.
27. Hubacek J.A., Viklicky O., Dlouha D., et al. The FTO gene polymorphism is associated with end-stage renal disease: two large independent case-control studies in a general population. Nephrol Dial Transplant 2012, 27:1030-1035.
28. Sonestedt E., Gullberg B., Ericson U., et al. Association between fat intake, physical activity and mortality depending on genetic variation in FTO. Int J Obes (Lond) 2011, 35:1041-1049.
29. Zimmermann E., Kring S.I., Berentzen T.L., et al. Fatness-associated FTO gene variant increases mortality independent of fatness - in cohorts of Danish men. PLoS One 2009, 4:e4428.
30. Dlouha D., Suchanek P., Lanska V., et al. Body mass index change in females after short-time life style intervention is not dependent on the FTO polymorphisms. Physiol Res 2011, 60:199-202.
31. Jia G., Yang C.G., Yang S., et al. Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett 2008, 582:3313-3319.
32. Wu Q., Saunders R.A., Szkudlarek-Mikho M., et al. The obesity-associated Fto gene is a transcriptional coactivator. Biochem Biophys Res Commun 2010, 401:390-395.
33. Samani N.J., Boultby R., Butler R., et al. Telomere shortening in atherosclerosis. Lancet 2001, 358:472-473.
34. Brouilette S.W., Whittaker A., Stevens S.E., et al. Telomere length is shorter in healthy offspring of subjects with coronary artery disease: support for the telomere hypothesis. Heart 2008, 94:422-425.
35. Bacchetti S., Counter C.M. Telomere and telomerase in human cancer. Int J Oncol 1995, 7:423-432.
36. Wang Y., Meeker A.K., Kowalski J., et al. Telomere length is related to alternative splice patterns of telomerase in thyroid tumors. Am J Pathol 2011, 179:1415-1424.
37. Wills L.P., Schnellmann R.G. Telomeres and telomerase in renal health. J Am Soc Nephrol 2011, 22:39-41.
38. Murillo-Ortiz B., Albarrán-Tamayo F., Arenas-Aranda D., et al. Telomere length and type 2 diabetes in males, a premature aging syndrome. Aging Male 2012, 15(1):54-58.
39. Wensley F., Gao P., Burgess S., et al. Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ 2011, 342:d548.