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Volumn 401, Issue 3, 2010, Pages 390-395

The obesity-associated Fto gene is a transcriptional coactivator

Author keywords

Adipogenesis; CCAAT enhancer binding protein; DNA methylation; Fto; Obesity; Transcriptional coactivator

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; NUCLEASE;

EID: 77958150921     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.09.064     Document Type: Article
Times cited : (85)

References (41)
  • 1
    • 70349207410 scopus 로고    scopus 로고
    • Annual medical spending attributable to obesity: payer-and service-specific estimates
    • Finkelstein E.A., Trogdon J.G., Cohen J.W., Dietz W. Annual medical spending attributable to obesity: payer-and service-specific estimates. Health Aff. (Millwood) 2009, 28:w822-w831.
    • (2009) Health Aff. (Millwood) , vol.28
    • Finkelstein, E.A.1    Trogdon, J.G.2    Cohen, J.W.3    Dietz, W.4
  • 2
    • 0035436344 scopus 로고    scopus 로고
    • Dietary and genetic influences on susceptibility or resistance to weight gain on a high fat diet
    • Mercer J.G. Dietary and genetic influences on susceptibility or resistance to weight gain on a high fat diet. Nutr. Metab. Cardiovasc. Dis. 2001, 11:114-117.
    • (2001) Nutr. Metab. Cardiovasc. Dis. , vol.11 , pp. 114-117
    • Mercer, J.G.1
  • 4
    • 33646877246 scopus 로고    scopus 로고
    • Epidemiology, trends, and morbidities of obesity and the metabolic syndrome
    • Bray G.A., Bellanger T. Epidemiology, trends, and morbidities of obesity and the metabolic syndrome. Endocrine 2006, 29:109-117.
    • (2006) Endocrine , vol.29 , pp. 109-117
    • Bray, G.A.1    Bellanger, T.2
  • 6
    • 33746377553 scopus 로고    scopus 로고
    • Obesity-related derangements in metabolic regulation
    • Muoio D.M., Newgard C.B. Obesity-related derangements in metabolic regulation. Annu. Rev. Biochem. 2006, 75:367-401.
    • (2006) Annu. Rev. Biochem. , vol.75 , pp. 367-401
    • Muoio, D.M.1    Newgard, C.B.2
  • 7
    • 69249208526 scopus 로고    scopus 로고
    • Gene-environment interactions and obesity - further aspects of genomewide association studies
    • Andreasen C.H., Andersen G. Gene-environment interactions and obesity - further aspects of genomewide association studies. Nutrition 2009, 25:998-1003.
    • (2009) Nutrition , vol.25 , pp. 998-1003
    • Andreasen, C.H.1    Andersen, G.2
  • 9
    • 50949104331 scopus 로고    scopus 로고
    • Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population
    • Chang Y.C., Liu P.H., Lee W.J., Chang T.J., Jiang Y.D., Li H.Y., Kuo S.S., Lee K.C., Chuang L.M. Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population. Diabetes 2008, 57:2245-2252.
    • (2008) Diabetes , vol.57 , pp. 2245-2252
    • Chang, Y.C.1    Liu, P.H.2    Lee, W.J.3    Chang, T.J.4    Jiang, Y.D.5    Li, H.Y.6    Kuo, S.S.7    Lee, K.C.8    Chuang, L.M.9
  • 10
    • 34249777814 scopus 로고    scopus 로고
    • Variation in FTO contributes to childhood obesity and severe adult obesity
    • Dina C., Meyre D., Gallina S., et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat. Genet. 2007, 39:724-726.
    • (2007) Nat. Genet. , vol.39 , pp. 724-726
    • Dina, C.1    Meyre, D.2    Gallina, S.3
  • 11
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling T.M., Timpson N.J., Weedon M.N., et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007, 316:889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3
  • 12
    • 44349142294 scopus 로고    scopus 로고
    • Common variants near MC4R are associated with fat mass, weight and risk of obesity
    • Loos R.J., Lindgren C.M., Li S., et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat. Genet. 2008, 40:768-775.
    • (2008) Nat. Genet. , vol.40 , pp. 768-775
    • Loos, R.J.1    Lindgren, C.M.2    Li, S.3
  • 13
    • 36749041363 scopus 로고    scopus 로고
    • The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
    • Gerken T., Girard C.A., Tung Y.C., et al. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 2007, 318:1469-1472.
    • (2007) Science , vol.318 , pp. 1469-1472
    • Gerken, T.1    Girard, C.A.2    Tung, Y.C.3
  • 14
    • 39049154918 scopus 로고    scopus 로고
    • The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily
    • Sanchez-Pulido L., Andrade-Navarro M.A. The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily. BMC Biochem. 2007, 8:23.
    • (2007) BMC Biochem. , vol.8 , pp. 23
    • Sanchez-Pulido, L.1    Andrade-Navarro, M.A.2
  • 15
    • 0034664066 scopus 로고    scopus 로고
    • Defective processing of methylated single-stranded DNA by E. coli AlkB mutants
    • Dinglay S., Trewick S.C., Lindahl T., Sedgwick B. Defective processing of methylated single-stranded DNA by E. coli AlkB mutants. Genes Dev. 2000, 14:2097-2105.
    • (2000) Genes Dev. , vol.14 , pp. 2097-2105
    • Dinglay, S.1    Trewick, S.C.2    Lindahl, T.3    Sedgwick, B.4
  • 17
    • 0742305875 scopus 로고    scopus 로고
    • Repairing DNA-methylation damage
    • Sedgwick B. Repairing DNA-methylation damage. Nat. Rev. Mol. Cell Biol. 2004, 5:148-157.
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 148-157
    • Sedgwick, B.1
  • 18
    • 54849381000 scopus 로고    scopus 로고
    • Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
    • Jia G., Yang C.G., Yang S., Jian X., Yi C., Zhou Z., He C. Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett. 2008, 582:3313-3319.
    • (2008) FEBS Lett. , vol.582 , pp. 3313-3319
    • Jia, G.1    Yang, C.G.2    Yang, S.3    Jian, X.4    Yi, C.5    Zhou, Z.6    He, C.7
  • 20
    • 34249727164 scopus 로고    scopus 로고
    • Transcriptional coregulators in the control of energy homeostasis
    • Feige J.N., Auwerx J. Transcriptional coregulators in the control of energy homeostasis. Trends Cell Biol. 2007, 17:292-301.
    • (2007) Trends Cell Biol. , vol.17 , pp. 292-301
    • Feige, J.N.1    Auwerx, J.2
  • 23
    • 0032732788 scopus 로고    scopus 로고
    • Relationships between chromatin organization and DNA methylation in determining gene expression
    • Jones P.L., Wolffe A.P. Relationships between chromatin organization and DNA methylation in determining gene expression. Semin. Cancer Biol. 1999, 9:339-347.
    • (1999) Semin. Cancer Biol. , vol.9 , pp. 339-347
    • Jones, P.L.1    Wolffe, A.P.2
  • 26
    • 43749098985 scopus 로고    scopus 로고
    • DNA methylation landscapes: provocative insights from epigenomics
    • Suzuki M.M., Bird A. DNA methylation landscapes: provocative insights from epigenomics. Nat. Rev. Genet. 2008, 9:465-476.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 465-476
    • Suzuki, M.M.1    Bird, A.2
  • 27
    • 0034623007 scopus 로고    scopus 로고
    • Gilbert's conjecture: the search for DNA (cytosine-5) demethylases and the emergence of new functions for eukaryotic DNA (cytosine-5) methyltransferases
    • Smith S.S. Gilbert's conjecture: the search for DNA (cytosine-5) demethylases and the emergence of new functions for eukaryotic DNA (cytosine-5) methyltransferases. J. Mol. Biol. 2000, 302:1-7.
    • (2000) J. Mol. Biol. , vol.302 , pp. 1-7
    • Smith, S.S.1
  • 29
    • 33244483352 scopus 로고    scopus 로고
    • OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis
    • Wolins N.E., Quaynor B.K., Skinner J.R., Tzekov A., Park C., Choi K., Bickel P.E. OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis. J. Lipid Res. 2006, 47:450-460.
    • (2006) J. Lipid Res. , vol.47 , pp. 450-460
    • Wolins, N.E.1    Quaynor, B.K.2    Skinner, J.R.3    Tzekov, A.4    Park, C.5    Choi, K.6    Bickel, P.E.7
  • 30
    • 0029094037 scopus 로고
    • A single amino acid change in the mouse peroxisome proliferator-activated receptor alpha alters transcriptional responses to peroxisome proliferators
    • Hsu M.H., Palmer C.N., Griffin K.J., Johnson E.F. A single amino acid change in the mouse peroxisome proliferator-activated receptor alpha alters transcriptional responses to peroxisome proliferators. Mol. Pharmacol. 1995, 48:559-567.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 559-567
    • Hsu, M.H.1    Palmer, C.N.2    Griffin, K.J.3    Johnson, E.F.4
  • 31
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer S.A., Umesono K., Noonan D.J., Heyman R.A., Evans R.M. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 1992, 358:771-774.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 32
    • 0141480198 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation
    • Kovacs K.A., Steinmann M., Magistretti P.J., Halfon O., Cardinaux J.R. CCAAT/enhancer-binding protein family members recruit the coactivator CREB-binding protein and trigger its phosphorylation. J. Biol. Chem. 2003, 278:36959-36965.
    • (2003) J. Biol. Chem. , vol.278 , pp. 36959-36965
    • Kovacs, K.A.1    Steinmann, M.2    Magistretti, P.J.3    Halfon, O.4    Cardinaux, J.R.5
  • 33
    • 73349104113 scopus 로고    scopus 로고
    • Active DNA demethylation mediated by DNA glycosylases
    • Zhu J.K. Active DNA demethylation mediated by DNA glycosylases. Annu. Rev. Genet. 2009, 43:143-166.
    • (2009) Annu. Rev. Genet. , vol.43 , pp. 143-166
    • Zhu, J.K.1
  • 34
    • 0033083803 scopus 로고    scopus 로고
    • Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity
    • Wu Z., Rosen E.D., Brun R., Hauser S., Adelmant G., Troy A.E., McKeon C., Darlington G.J., Spiegelman B.M. Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol. Cell 1999, 3:151-158.
    • (1999) Mol. Cell , vol.3 , pp. 151-158
    • Wu, Z.1    Rosen, E.D.2    Brun, R.3    Hauser, S.4    Adelmant, G.5    Troy, A.E.6    McKeon, C.7    Darlington, G.J.8    Spiegelman, B.M.9
  • 35
    • 56749157389 scopus 로고    scopus 로고
    • Transcription-coupled DNA repair: two decades of progress and surprises
    • Hanawalt P.C., Spivak G. Transcription-coupled DNA repair: two decades of progress and surprises. Nat. Rev. Mol. Cell Biol. 2008, 9:958-970.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 958-970
    • Hanawalt, P.C.1    Spivak, G.2
  • 36
    • 45449114804 scopus 로고    scopus 로고
    • The colorful history of active DNA demethylation
    • Ooi S.K., Bestor T.H. The colorful history of active DNA demethylation. Cell 2008, 133:1145-1148.
    • (2008) Cell , vol.133 , pp. 1145-1148
    • Ooi, S.K.1    Bestor, T.H.2
  • 39
    • 0031025997 scopus 로고    scopus 로고
    • Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G
    • Cooper P.K., Nouspikel T., Clarkson S.G., Leadon S.A. Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G. Science 1997, 275:990-993.
    • (1997) Science , vol.275 , pp. 990-993
    • Cooper, P.K.1    Nouspikel, T.2    Clarkson, S.G.3    Leadon, S.A.4
  • 40
    • 0030256151 scopus 로고    scopus 로고
    • Effects of perturbations of the hypothalamic-pituitary-adrenal axis on the acute phase response: altered C/EBP and acute phase response gene expression in lipopolysaccharide-treated rats
    • Eastman H.B., Fawcett T.W., Udelsman R., Holbrook N.J. Effects of perturbations of the hypothalamic-pituitary-adrenal axis on the acute phase response: altered C/EBP and acute phase response gene expression in lipopolysaccharide-treated rats. Shock 1996, 6:286-292.
    • (1996) Shock , vol.6 , pp. 286-292
    • Eastman, H.B.1    Fawcett, T.W.2    Udelsman, R.3    Holbrook, N.J.4
  • 41
    • 0037707799 scopus 로고    scopus 로고
    • Categorically distinct acute stressors elicit dissimilar transcriptional profiles in the paraventricular nucleus of the hypothalamus
    • Reyes T.M., Walker J.R., DeCino C., Hogenesch J.B., Sawchenko P.E. Categorically distinct acute stressors elicit dissimilar transcriptional profiles in the paraventricular nucleus of the hypothalamus. J. Neurosci. 2003, 23:5607-5616.
    • (2003) J. Neurosci. , vol.23 , pp. 5607-5616
    • Reyes, T.M.1    Walker, J.R.2    DeCino, C.3    Hogenesch, J.B.4    Sawchenko, P.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.