Suppression of tumor growth in xenograft model mice by small interfering RNA targeting osteopontin delivery using biocompatible poly(amino ester)

International Journal of Pharmaceutics

Volumn 431, Issue 1-2, 2012, Pages 197-203

  Minai Tehrani, Arash ^a   Jiang, Hu Lin ^a,b   Kim, You Kyoung ^a,b   Chung, Youn Sun ^a   Yu, Kyeong Nam ^a   Kim, Ji Eun ^a   Shin, Ji Young ^a   Hong, Seong Ho ^a   Lee, Jae Ho ^a   Kim, Hye Joon ^a   Chang, Seung Hee ^a   Park, Sungjin ^a   Kang, Bit Na ^a   Cho, Chong Su ^a   Cho, Myung Haing ^a,c  

^a Seoul National University   (South Korea)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c Seoul National University   (South Korea)

Author keywords

Cancer gene therapy; Osteopontin; Poly(amino ester); siRNA

Indexed keywords

DRUG CARRIER; FIBROBLAST GROWTH FACTOR 2; GELATINASE B; GLYCEROL PROPOXYLATE TRIACRYLATE; OSTEOPONTIN; POLYMER; RIBONUCLEASE; SMALL INTERFERING RNA; SPERMINE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER GENE THERAPY; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME DEGRADATION; GENE SILENCING; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

ACRYLATES; ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; FIBROBLAST GROWTH FACTOR 2; GENETIC THERAPY; HUMANS; MATRIX METALLOPROTEINASE 9; MICE; MICE, NUDE; OSTEOPONTIN; PROLIFERATING CELL NUCLEAR ANTIGEN; RNA, SMALL INTERFERING; SPERMINE; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84861334417     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.04.028     Document Type: Article

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