Involvement of endothelial PECAM-1/CD31 in angiogenesis

American Journal of Pathology

Volumn 151, Issue 3, 1997, Pages 671-677

  DeLisser, Horace M ^a   Christofidou Solomidou, Melpo ^a   Strieter, Robert M ^b   Burdick, Marie D ^b   Robinson, Candy S ^c   Wexler, Roseanne S ^c   Kerr, Janet S ^c   Garlanda, Cecilia ^d   Merwin, June R ^e   Madri, Joseph A ^e   Albelda, Steven M ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c DUPONT COMPANY   (United States)

^d MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^e YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CD31 ANTIGEN;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CULTURE; CELL INTERACTION; CELL JUNCTION; CELL MIGRATION; CORNEA NEOVASCULARIZATION; ENDOTHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD31; CELLS, CULTURED; COLLAGEN; CORNEA; DRUG COMBINATIONS; ENDOTHELIUM; FIBROBLAST GROWTH FACTOR 2; HUMANS; LAMININ; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030953387     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Arnold F, West DC: Angiogenesis in wound healing. Pharmacol Ther 1991, 52:407-422
2. Folkman J: Clinical applications of research on angiogenesis. N Engl J Med 1995, 333:1757-1763
3. Folkman J, Shing Y: Angiogenesis. J Biol Chem 1992, 267:10931-10934
4. McCormick BA, Zetter BR: Adhesive interactions in angiogenesis and metastasis. Pharmacol Ther 1992, 53:239-260
5. Polverini PJ: Cellular adhesion molecules: newly identified mediators of angiogenesis. Am J Pathol 1996, 148:1023-1029
6. Bischoff J: Cell adhesion and angiogenesis. J Clin Invest 1997, 99: 373-376
7. Albelda SM, Buck CA: Integrins and other cell adhesion molecules. FASEB J 1990, 4:2868-2880
8. Hynes RO: Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992, 69:11-25
9. Albelda SM: Differential expression of integrin cell-substratum adhesion receptors on endothelium. Angiogenesis Key Principles-Science-Technology-Medicine. Edited by R Steiner, PB Weisz, R Langer. Basel, Birkhauser Verlag, 1992, pp 188-192
10. Luscinskas FW, Lawler J: Integrins as dynamic regulators of vascular function. FASEB J 1994, 8:929-938
11. Brooks PC, Clark RAF, Cheresh DA: Requirement of integrin αvβ3 for angiogenesis. Science 1994, 264:569-571
12. Brooks PC, Montgomery AMP, Rosenfeld M, Reisfeld RA, Hu T, Klier G, Cheresh DA: Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994 79: 1157-1164
13. Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA, Cheresh DA: Definition of two angiogenic pathways by distinct av integrins. Science 1995, 270:1500-1502
14. Hammes P, Brownlee M, Jonczyk A, Sutter A, Preissner K: Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibit retinal neovascularization. Nature Medicine 1996, 2:529-533
15. Lampugnani MG, Resnati M, Raiteri M, Pigott R, Pisacane A, Houen G, Ruco LP, Dejana E: A novel endothelial-specific membrane protein is a marker of cell-cell contacts. J Cell Biol 1992, 118:1511-1522
16. Aylon O, Sabanai H, Lampugnani M, DeJana E, Geiger B: Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells. J Cell Biol 1994, 126:247-258
17. Breviario F, Caveda L, Corada M, Martin-Padura I, Navarro P, Golay J, Introna M, Gulino D, Lampugnani MG, Dejana E: Functional properties of human vascular endothelial cadherin (7B4/cadherin-5), an endothelium-specific cadherin. Arterioscler Thromb Vasc Biol 1995, 15:1229-1239
18. Muller WA, Ratti CM, McDonnell SL, Cohn ZA: A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions. J Exp Med 1989, 170:399-414
19. Albelda SM, Oliver PD, Romer LH, Buck CA: Endo-CAM: a novel endothelial cell-cell adhesion molecule. J Cell Biol 1990, 110:1227-1237
20. Newman PJ, Berndt MC, Gorski J, White GC, II, Lyman S, Paddock C, Muller WA: PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 1990, 247: 1219-1222
21. DeLisser HM, Newman PJ, Albelda SM: Molecular and functional aspects of PECAM-1/CD31. Immunol Today 1994, 15:490-495
22. Romer LH, McLean NV, Yan H-C, Daise M, Sun J, DeLisser HM: IFN-γ, and TNF-α induce redistribution of PECAM-1 (CD31) on human endothelial cells. J Immunol 1995, 154:6582-6592
23. Matsumura T, Wolff K, Petzelbauer P: Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actin. J Immunol 1997, 158:3408-3416
24. Albelda SM, Muller WA, Buck CA, Newman PJ: Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule. J Cell Biol 1991, 114:1059-1068
25. Vecchi A, Garlanda C, Lampugnani MG, Resnati M, Matteucci C, Stoppacciaro A, Schnurch H, Risau W, Ruco L, Mantovani A, Dejana E: Monoclonal antibodies specific for endothelial cells of mouse blood vessels: their application in the identification of adult and embryonic endothelium. Eur J Cell Biol 1994, 63:247-254
26. Baldwin HS, Shen HM, Yan H-C, DeLisser HM, Chung A, Mickanin C, Trask T, Kirschbaum NE, Newman PJ, Albelda SM, Buck CA: Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development 1994, 120:2539-2553
27. Burns AR, Takei F, Doerschuk CM: Quantitation of ICAM-1 expression in mouse during pneumonia. J Immunol 1994, 153:3189-3198
28. Basson CT, Knowles WJ, Bell L, Albelda SM, Castronovo V, Liotta L, Madri JA: Spatiotemperal segregation of endothelial cell integrin and non-integrin extracellular matrix binding proteins during adhresion events. J Cell Biol 1990, 110:789-801
29. Madri JA, Williams SK: Capillary endothelial cell cultures: phenotypic modulation by matrix components. J Cell Biol 1983, 97:153-165
30. Merwin JR, Madri JA, Lynch M: Colon carcinoma cell binding to ELAM-1 transfected endothelia. Biochem Biophys Res Commun 1992, 189:315-323
31. Romanic A, Madri JA: The induction of 72 kDa gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent. J Cell Biol 1994, 125:1165-1178
32. Madri JA, Pratt BM, Tucker AM: Phenotypic modulation of endothelial cells by transforming growth factor-β depends upon the composition and organization of the extracellular matrix. J Cell Biol 1988, 106: 1375-1384
33. Arenberg DA, Kunkel SL, Polverini PJ, Glass M, Burdick MD, Strieter RM: Inhibition of interlukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice. J Clin Invest 1995, 97:2792-2802
34. Arenberg DA, Kunkel SL, Polverini PJ, Morris SB, Burdick MD, Glass M, Taub DT, Iannettoni MD, Whyte RI, Strieter RM: Interferon-ginducible protein 10 (IP-10) is an angiostatic factor that inhibits human non-small cell lung cancer (NSCLC) tumorigenesis and spontaneous metastases. J Exp Med 1996, 184:981-992
35. Passaniti A, Taylor RM, Pili R, Guo Y, Long PV, Haney JA, Pauly RR, Grant DS, Martin GR: A simple, quantitative method for assessing angiogenesis, and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor. Lab Invest 1992, 67:519-528
36. Merwin JR, Anderson JM, Kocher O, Van Itallie CM, Madri JA: Transforming growth factor-β 1 modulates extracellular matrix organization and cell-cell junctional complex formation during in vitro angiogenesis. J Cell Physiol 1990, 142:117-128
37. Vaporciyan AA, DeLisser HM, Yan H-C, Mendiguren II, Thom SR, Jones ML, Ward PA, Albelda SM: Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science 1993, 262:1580-1582
38. Wakelin MW, Sanz M-J, Dewar A, Albelda SM, Larkin SW, Williams TJ, Boughton-Smith N, Nourshargh S: An anti-PECAM-1 antibody (CD31) antibody inhibits leukocyte extravasation across mesenteric microvessels in vivo by blocking the passage through the basement membrane. J Exp Med 1996, 184:229-239
39. Berger R, Albelda SM, Berd D, Ioffreda M, Whitaker D, Murphy GF: Expression of platelet-endothelial cell adhesion molecule (PECAM-1) during melanoma-induced angiogenesis in vivo. J Cutan Pathol 1993, 20:399-406
40. Yan H-C, Baldwin HS, Sun J, Buck CA, Albelda SM, DeLisser HM: Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1). J Biol Chem 1995, 270:23672-23680
41. Hanahan D, Folkman J: Patterns, and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996, 86:353-364
42. Tanaka Y, Albelda SM, Horgan KJ, van Seventer GA, Shimizu Y, Newman W, Hallam J, Newman P, Buck CA, Shaw S: CD31 expressed on distinctive T cell subsets is a preferential amplifier of b1 integrin-mediated adhesion. J Exp Med 1992, 176:245-253
43. Piali L, Albelda SM, Baldwin HS, Hammel P, Gisler RH, Imhof BA: Murine platelet endothelial cell adhesion molecule (PECAM-1)/CD31 modulates β2 integrins on lymphokine-activated killer cells. Eur J Immunol 1993, 23:2464-2471
44. + haematopoietic progenitor cells. J Immunol 1994, 153:4673-4683
45. Berman ME, Muller WA: Ligation of platelet/endothelial cell adhesion molecule 1 (PECAM/DC31) on monocytes and neutrophils increases the binding capacity of leukocyte CR3 (CD11D/CD18). J Immunol 1995, 154:299-307
46. Berman ME, Xie Y, Muller WA: Roles of platelet/endothelial cell adhesion molecule-1 (PECAM-1, CD31) in natural killer cell transendothelial migration and β2 integrin activation. J Immunol 1996, 156: 1515-1524
47. + hematopoietic precursor cells with early myeloid and B-lymphoid cell phenotypes. Blood 1993, 82: 2649-2663
48. Lastres P, Almendro N, Bellón T, López-Guerrero JA, Eritja R, Bernabéu C: Functional regulation of platelet/endothelial cell adhesion molecule-1 by TGF-b1 in promonocytic U-937 cells. J Immunol 1994, 153:4206-4218
49. Sun Q-H, DeLisser HM, Zukowski MM, Paddock C, Albelda SM, Newman PJ: Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity. J Biol Chem 1996, 271:11090-11098
50. Sun J, Williams J, Yan H-C, Amin KM, Albelda SM, DeLisser HM: Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression. J Biol Chem 1996, 271:18561-18570
51. 3 integrin involved in adhesion of leukocytes to endothelium. J Cell Biol 1995, 130:451-460
52. 3 as a heterotypic ligand for CD31/PECAM-1. J Cell Sci 1996, 109:437-445
53. DeLisser HM, Yan H-C, Newman PJ, Muller WA, Buck CA, Albelda SM: Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans. J Biol Chem 1993, 268:16037-16046
54. Prager E, Sunder-Plassmann R, Hansmann C, Koch C, Holter W, Knapp W, Stockinger H: Interaction of CD31 with a heterophilic counterreceptor involved in downregulation of human T cell responses. J Exp Med 1996, 184:41-50
55. Liao F, Huynh HK, Eiroa A, Greene T, Polizzi E, Muller WA: Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1. J Exp Med 1995, 182:1337-1343
56. Bogan S, Pak J, Garifallou M, Deng X, Muller WA: Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivo. J Exp Med 1994, 179:1059-1064
57. Murohara T, Delyani JA, Albelda SM, Lefer AM: Blockade of platelet endothelial cell adhesion molecule-1 protects against myocardial ischemia and reperfusion injury. J Immunol 1996, 156:3550-3557
58. Torimoto Y, Rothstein DM, Dang NH, Schlossman SF, Morimoto C: CD31, a novel cell surface marker for CD4 cells of supressor lineage, unaltered by state of activation. J Immunol 1992, 148:388-396
59. Zehnder JL, Shatsky M, Leung LLK, Butcher EC, McGregor JL, Levitt LJ: Involvement of CD31 in lymphocyte-mediated immune responses: importance of the membrane proximal immunoglobin domain and indentification of an inhibiting CD31 peptide. Blood 1995, 85:1282-1288