Mechanism of prostacyclin-induced potentiation of glucose-induced insulin secretion

Endocrinology

Volumn 153, Issue 6, 2012, Pages 2612-2622

  Gurgul Convey, Ewa ^a   Hanzelka, Katarzyna ^a   Lenzen, Sigurd ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATE; ARACHIDONIC ACID DERIVATIVE; CASPASE 3; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCOSE; ICOSANOID; INSULIN; PROSTACYCLIN; PROSTACYCLIN RECEPTOR; PROSTACYCLIN SYNTHASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; EXOCYTOSIS; GENE; GENE OVEREXPRESSION; INFLAMMATION; INSULIN RELEASE; INSULIN SYNTHESIS; MALE; METABOLITE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUTRIENT; PANCREAS FUNCTION; PANCREAS ISLET BETA CELL; PGIS GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; REGULATORY MECHANISM;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CYCLIC AMP; CYTOCHROME P-450 ENZYME SYSTEM; DRUG SYNERGISM; EPOPROSTENOL; GLUCOSE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INSULIN; INSULIN-SECRETING CELLS; INTRAMOLECULAR OXIDOREDUCTASES; ISLETS OF LANGERHANS; MALE; RATS; RATS, INBRED LEW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 84861325113     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-2027     Document Type: Article

References (56)

1. McDaniel ML, Kwon G, Hill JR, Marshall CA, Corbett JA 1996 Cytokines and nitric oxide in islet inflammation and diabetes. Proc Soc Exp Biol Med 211:24-32
2. Wellen KE, Hotamisligil GS 2005 Inflammation, stress, and diabetes. J Clin Invest 115:1111-1119 (Pubitemid 40629025)
3. Corbett JA, Kwon G, Turk J, McDaniel ML 1993 IL-1β induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of Langerhans: activation of cyclooxygenase by nitric oxide. Biochemistry 32:13767-13770
4. Tran PO, Gleason CE, Robertson RP 2002 Inhibition of interleukin-1beta- induced COX-2and EP3 gene expression by sodium salicylate enhances pancreatic islet β-cell function. Diabetes 51:1772-1778 (Pubitemid 34564289)
5. Robertson RP 1986 Arachidonic acid metabolite regulation of insulin secretion. Diabetes Metab Rev 2:261-296 (Pubitemid 16009510)
6. Robertson RP 1988 Eicosanoids as pluripotential modulators of pancreatic islet function. Diabetes 37:367-370 (Pubitemid 18096370)
7. Kelly KL, Laychock SG 1984 Activity of prostaglandin biosynthetic pathways in rat pancreatic islets. Prostaglandins 27:925-938 (Pubitemid 14069195)
8. Robertson RP, Tsai P, Little SA, Zhang HJ, Walseth TF 1987 Receptor-mediated adenylate cyclase-coupled mechanism for PGE2 inhibition of insulin secretion in HIT cells. Diabetes 36:1047-1053
9. Metz SA, Fujimoto WY, Robertson RP 1984 Oxygenation products of arachidonic acid: third messengers for insulin release. J Allergy Clin Immunol 74:391-402 (Pubitemid 14047480)
10. Metz S, VanRollins M, Strife R, Fujimoto W, Robertson RP 1983 Lipoxygenase pathway in islet endocrine cells. Oxidative metabolism of arachidonic acid promotes insulin release. J Clin Invest 71:1191-1205 (Pubitemid 13098905)
11. Landgraf R, Landgraf-Leurs MM 1979 The prostaglandins system and insulin release. Studies with the isolated perfused rat pancreas. Prostaglandins 17:599-613 (Pubitemid 9173774)
12. Haeggström JZ, Rinaldo-Matthis A, Wheelock CE, Wetterholm A 2010 Advances in eicosanoid research, novel therapeutic implications. Biochem Biophys Res Commun 396:135-139
13. Wu KK, Liou JY 2005 Cellular and molecular biology of prostacyclin synthase. Biochem Biophys Res Commun 338:45-52 (Pubitemid 41540535)
14. Arita S, Une S, Ohtsuka S, Kawahara T, Kasraie A, Smith CV, Mullen Y 2001 Increased islet viability by addition of beraprost sodium to collagenase solution. Pancreas 23:62-67 (Pubitemid 32592077)
15. Sieradzki J, Wolan H, Szczeklik A 1984 Effects of prostacyclin and its stable analog, iloprost, upon insulin secretion in isolated pancreatic islets. Prostaglandins 28:289-296 (Pubitemid 14023446)
16. Sato N, Kaneko M, Tamura M, Kurumatani H 2010 The prostacyclin analog beraprost sodium ameliorates characteristics of metabolic syndrome in obese Zucker (fatty) rats. Diabetes 59:1092-1100
17. Patrono C, Pugliese F, Ciabattoni G, Di Blasi S, Pierucci A, Cinotti GA, Maseri A, Chierchia S 1981 Prostacyclin does not affect insulin secretion in humans. Prostaglandins 21:379-385 (Pubitemid 11065227)
18. Ximenes HM, Lortz S, Jörns A, Lenzen S 2007 Triiodothyronine (T3)-mediated toxicity and induction of apoptosis in insulin-producing INS-1 cells. Life Sci 80:2045-2050 (Pubitemid 46678064)
19. Mosmann T 1983 Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63 (Pubitemid 14203433)
20. Gurgul E, Lortz S, Tiedge M, Jörns A, Lenzen S 2004 Mitochondrial catalase overexpression protects insulin-producing cells against toxicity of reactive oxygen species and proinflammatory cytokines. Diabetes 53:2271-2280 (Pubitemid 39145580)
21. Gurgul-Convey E, Lenzen S 2010 Protection against cytokine toxicity through endoplasmic reticulum and mitochondrial stress prevention by prostacyclin synthase overexpression in insulin-producing cells. J Biol Chem 285:11121-11128
22. Tiedge M, Höhne M, Lenzen S 1993 Insulin secretion, insulin content and glucose phosphorylation in RINm5F insulinoma cells after transfection with human GLUT2 glucose-transporter cDNA. Biochem J 296:113-118 (Pubitemid 23344737)
23. Baltrusch S, Langer S, Massa L, Tiedge M, Lenzen S 2006 Improved metabolic stimulus for glucose-induced insulin secretion through GK and PFK-2/FBPase-2 coexpression in insulin-producing RINm5F cells. Endocrinology 147:5768-5776 (Pubitemid 44833493)
24. Robertson RP 1995 Molecular regulation of prostaglandin synthesis: implications for endocrine systems. Trends Endocrinol Metab 6:293-297 (Pubitemid 26003818)
25. Robertson RP 1998 Dominance of cyclooxygenase-2 in the regulation of pancreatic islet prostaglandin synthesis. Diabetes 47:1379-1383
26. Kelly KL, Laychock SG 1981 Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. Prostaglandins 21:759-769
27. Metz SA, Robertson RP, Fujimoto WY 1981 Inhibition of prostaglandin E synthesis augments glucose-induced insulin secretion is cultured pancreas. Diabetes 30:551-557 (Pubitemid 11026625)
28. Robertson RP, Chen M, McRae JR, Metz SA 1979 Improvement of insulin secretion in diabetics by a prostaglandin synthesis inhibitor. Adv Exp Med Biol 119:227-231
29. Gerrard JM, Stuart MJ, Rao GH, Steffes MW, Mauer SM, Brown DM, White JG 1980 Alteration in the balance of prostaglandin and thromboxane synthesis in diabetic rats. J Lab Clin Med 95:950-958 (Pubitemid 10116968)
30. Giacco F, Brownlee M 2010 Oxidative stress and diabetic complications. Circ Res 107:1058-1070
31. Nie H, Wu JL, Zhang M, Xu J, Zou MH 2006 Endothelial nitric oxide synthase-dependent tyrosine nitration of prostacyclin synthase in diabetes in vivo. Diabetes 55:3133-3141 (Pubitemid 44923653)
32. Sprague RS, Bowles EA, Hanson MS, DuFaux EA, Sridharan M, Adderley S, Ellsworth ML, Stephenson AH 2008 Prostacyclin analogs stimulate receptor-mediated cAMP synthesis and ATP release from rabbit and human erythrocytes. Microcirculation 15:461-471 (Pubitemid 351927733)
33. MacDonald PE, Obermüller S, Vikman J, Galvanovskis J, Rorsman P, Eliasson L 2005 Regulated exocytosis and kiss-and-run of synaptic-like microvesicles in INS-1 and primary rat β-cells. Diabetes 54:736-743 (Pubitemid 40322076)
34. Eliasson L, Ma X, Renström E, Barg S, Berggren PO, Galvanovskis J, Gromada J, Jing X, Lundquist I, Salehi A, Sewing S, Rorsman P 2003 SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic β-cells. J Gen Physiol 121:181-197
35. Gromada J, Ding WG, Barg S, Renström E, Rorsman P 1997 Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors. Pflugers Arch 434:515-524 (Pubitemid 27355170)
36. Renström E, Eliasson L, Rorsman P 1997 Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic β-cells. J Physiol 502:105-118 (Pubitemid 27322979)
37. Ammälä C, Ashcroft FM, Rorsman P 1993 Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells. Nature 363:356-358 (Pubitemid 23161532)
38. Hanna ST, Pigeau GM, Galvanovskis J, Clark A, Rorsman P, MacDonald PE 2009 Kiss-and-run exocytosis and fusion pores of secretory vesicles in human β-cells. Pflugers Arch 457:1343-1350
39. Idevall-Hagren O, Barg S, Gylfe E, Tengholm A 2010 cAMP mediators of pulsatile insulin secretion from glucose-stimulated single β-cells. J Biol Chem 285:23007-23018
40. Fujimoto K, Shibasaki T, Yokoi N, Kashima Y, Matsumoto M, Sasaki T, Tajima N, Iwanaga T, Seino S 2002 Piccolo, a Ca2+sensor in pancreatic β-cells. Involvement of cAMP-GEFII. Rim2. Piccolo complex in cAMP-dependent exocytosis. J Biol Chem 277:50497-50502 (Pubitemid 36042206)
41. Shibasaki T, Takahashi H, Miki T, Sunaga Y, Matsumura K, Yamanaka M, Zhang C, Tamamoto A, Satoh T, Miyazaki J, Seino S 2007 Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP. Proc Natl Acad Sci USA 104:19333-19338
42. Vikman J, Svensson H, Huang YC, Kang Y, Andersson SA, Gaisano HY, Eliasson L 2009 Truncation of SNAP-25 reduces the stimulatory action of cAMP on rapid exocytosis in insulin-secreting cells. Am J Physiol Endocrinol Metab 297:E452-E461
43. Kwan EP, Gao X, Leung YM, Gaisano HY 2007 Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase A regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet β cells. Pancreas 35:e45-e54 (Pubitemid 47482535)
44. Dzhura I, Chepurny OG, Kelley GG, Leech CA, Roe MW, Dzhura E, Afshari P, Malik S, Rindler MJ, Xu X, Lu Y, Smrcka AV, Holz GG 2010 Epac2-dependent mobilization of intracellular Ca2+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice. J Physiol 588:4871-4889
45. Cunha DA, Ladrière L, Ortis F, Igoillo-Esteve M, Gurzov EN, Lupi R, Marchetti P, Eizirik DL, Cnop M 2009 Glucagon-like peptide-1 agonists protect pancreatic β-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB. Diabetes 58:2851-2862
46. Eizirik DL, Cnop M 2010 ER stress in pancreatic β cells: the thin red line between adaptation and failure. Sci Signal 3:pe7
47. Hotamisligil GS 2010 Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140:900-917
48. Rabinovitch A, Blondel B, Murray T, Mintz DH 1980 Cyclic adenosine-3′,5′-monophosphate stimulates islet B cell replication in neonatal rat pancreatic monolayer cultures. J Clin Invest 66:1065-1071 (Pubitemid 11233808)
49. Kunugiza Y, Tomita N, Taniyama Y, Tomita T, Osako MK, Tamai K, Tanabe T, Kaneda Y, Yoshikawa H, Morishita R 2006 Acceleration of wound healing by combined gene transfer of hepatocyte growth factor and prostacyclin synthase with Shima Jet. Gene Therapy 13:1143-1152 (Pubitemid 44084073)
50. Dalle S, Quoyer J, Varin E, Costes S 2011 Roles and regulation of the transcription factor CREB in pancreatic β-cells. Curr Mol Pharmacol 4:187-195
51. Lizcano JM, Morrice N, Cohen P 2000 Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155. Biochem J 349:547-557 (Pubitemid 30465790)
52. Ashcroft SJ, Weerasinghe LC, Randle PJ 1973 Interrelationship of islet metabolism, adenosine triphosphate content and insulin release. Biochem J 132:223-231
53. McTaggart JS, Clark RH, Ashcroft FM 2010 The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet. J Physiol 588:3201-3209
54. Lang J 1999 Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion. Eur J Biochem 259:3-17 (Pubitemid 29030812)
55. Eliasson L, Renström E, Ding WG, Proks P, Rorsman P 1997 Rapid ATP-dependent priming of secretory granules precedes Ca(2+)-induced exocytosis in mouse pancreatic B-cells. J Physiol 503:399-412 (Pubitemid 27423364)
56. Otsuki M, Goya K, Kasayama S 2005 Vascular endothelium as a target of beraprost sodium and fenofibrate for antiatherosclerotic therapy in type 2 diabetes mellitus. Vasc Health Risk Manag 1:209-215