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Volumn 59, Issue 4, 2010, Pages 1092-1100

The prostacyclin analog beraprost sodium ameliorates characteristics of metabolic syndrome in obese zucker (fatty) rats

Author keywords

[No Author keywords available]

Indexed keywords

BERAPROST; CHOLESTEROL; GLUCOSE; INSULIN; N ACETYL BETA GLUCOSAMINIDASE; TRIACYLGLYCEROL;

EID: 77951166668     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db09-1432     Document Type: Article
Times cited : (49)

References (48)
  • 1
    • 0027512732 scopus 로고
    • Role of insulin resistance in human disease (syndrome X): An expanded definition
    • Reaven GM. Role of insulin resistance in human disease (syndrome X): an expanded definition. Annu Rev Med 1993;44:121-131
    • (1993) Annu Rev Med , vol.44 , pp. 121-131
    • Reaven, G.M.1
  • 2
    • 0033942001 scopus 로고    scopus 로고
    • Insulin action and insulin resistance in human skeletal muscle
    • Zierath JR, Krook A, Wallberg-Henriksson H. Insulin action and insulin resistance in human skeletal muscle. Diabetologia 2000;43:821-835
    • (2000) Diabetologia , vol.43 , pp. 821-835
    • Zierath, J.R.1    Krook, A.2    Wallberg-Henriksson, H.3
  • 3
    • 0018822167 scopus 로고
    • Insulin resistance in soleus muscle from obese Zucker rats: Involvement of several defective sites
    • Crettaz M, Prentki M, Zaninetti D, Jeanrenaud B. Insulin resistance in soleus muscle from obese Zucker rats: involvement of several defective sites. Biochem J 1980;186:525-534
    • (1980) Biochem J , vol.186 , pp. 525-534
    • Crettaz, M.1    Prentki, M.2    Zaninetti, D.3    Jeanrenaud, B.4
  • 4
    • 26944445630 scopus 로고    scopus 로고
    • Advances in diabetes for the millennium: Diabetes and the endothelium
    • Dandona P, Aljada A. Advances in diabetes for the millennium: diabetes and the endothelium. Med Genet Med 2004;6(Suppl.):6
    • (2004) Med Genet Med , vol.6 , Issue.SUPPL. , pp. 6
    • Dandona, P.1    Aljada, A.2
  • 5
    • 33645509709 scopus 로고    scopus 로고
    • Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation
    • Du X, Edelstein D, Obici S, Higham N, Zou MH, Brownlee M. Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation. J Clin Invest 2006;116:1071-1080
    • (2006) J Clin Invest , vol.116 , pp. 1071-1080
    • Du, X.1    Edelstein, D.2    Obici, S.3    Higham, N.4    Zou, M.H.5    Brownlee, M.6
  • 7
    • 67650896212 scopus 로고    scopus 로고
    • Attenuation of renoinflammatory cascade in experimental model of diabetic nephropathy by sesamol
    • Kuhad A, Sachdeva AK, Chopra K. Attenuation of renoinflammatory cascade in experimental model of diabetic nephropathy by sesamol. J Agric Food Chem 2009;57:6123-6128
    • (2009) J Agric Food Chem , vol.57 , pp. 6123-6128
    • Kuhad, A.1    Sachdeva, A.K.2    Chopra, K.3
  • 8
    • 77951186860 scopus 로고    scopus 로고
    • Peroxynitrite-induced protein nitration is responsible for renal mitochondrial damage in diabetic rat
    • 11 September [Epub ahead of print]
    • Liang JH, Li YN, Qi JS, Jia XX. Peroxynitrite-induced protein nitration is responsible for renal mitochondrial damage in diabetic rat. J Endocrinol Invest. 11 September 2009 [Epub ahead of print]
    • (2009) J Endocrinol Invest
    • Liang, J.H.1    Li, Y.N.2    Qi, J.S.3    Jia, X.X.4
  • 9
    • 0034850904 scopus 로고    scopus 로고
    • Effect of insulin on nitric oxide synthase-like immunostaining of arteries in various organs in Zucker diabetic fatty rats
    • Kawaguchi M, Koshimura K, Sohmiya M, Murakami Y, Gonda T, Kato Y. Effect of insulin on nitric oxide synthase-like immunostaining of arteries in various organs in Zucker diabetic fatty rats. Eur J Endocrinol 2001;145: 343-349
    • (2001) Eur J Endocrinol , vol.145 , pp. 343-349
    • Kawaguchi, M.1    Koshimura, K.2    Sohmiya, M.3    Murakami, Y.4    Gonda, T.5    Kato, Y.6
  • 10
    • 37549053729 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase depresses cardiac contractile function in Zucker diabetic fatty rats
    • Song D, Kuo KH, Yao R, Hutchings SR, Pang CC. Inducible nitric oxide synthase depresses cardiac contractile function in Zucker diabetic fatty rats. Eur J Pharmacol 2008;579:253-259
    • (2008) Eur J Pharmacol , vol.579 , pp. 253-259
    • Song, D.1    Kuo, K.H.2    Yao, R.3    Hutchings, S.R.4    Pang, C.C.5
  • 11
    • 0141831989 scopus 로고    scopus 로고
    • Transcriptional stimulation of the eNOS gene by the stable prostacyclin analogue beraprost is mediated through cAMP-responsive element in vascular endothelial cells: Close link between PGI2 signal and NO pathways
    • Niwano K, Arai M, Tomaru K, Uchiyama T, Ohyama Y, Kurabayashi M. Transcriptional stimulation of the eNOS gene by the stable prostacyclin analogue beraprost is mediated through cAMP-responsive element in vascular endothelial cells: close link between PGI2 signal and NO pathways. Circ Res 2003;93:523-530
    • (2003) Circ Res , vol.93 , pp. 523-530
    • Niwano, K.1    Arai, M.2    Tomaru, K.3    Uchiyama, T.4    Ohyama, Y.5    Kurabayashi, M.6
  • 13
    • 0030297438 scopus 로고    scopus 로고
    • Acute effect of beraprost sodium on lower limb circulation in patients with non-insulin-dependent diabetes mellitus-evaluation by color Doppler ultrasonography and laser cutaneous blood flowmetry
    • Okuda Y, Sone H, Mizutani S, Asano M, Tsurushima Y, Ogawa M, Tada K, Asakura Y, Kawakami Y, Suzuki S, Yamashita K. Acute effect of beraprost sodium on lower limb circulation in patients with non-insulin-dependent diabetes mellitus-evaluation by color Doppler ultrasonography and laser cutaneous blood flowmetry. Prostaglandins 1996;52:375-384
    • (1996) Prostaglandins , vol.52 , pp. 375-384
    • Okuda, Y.1    Sone, H.2    Mizutani, S.3    Asano, M.4    Tsurushima, Y.5    Ogawa, M.6    Tada, K.7    Asakura, Y.8    Kawakami, Y.9    Suzuki, S.10    Yamashita, K.11
  • 14
    • 0035340014 scopus 로고    scopus 로고
    • Changes in skin blood flow in type 2 diabetes induced by prostacyclin: Association with ankle brachial index and plasma thrombomodulin levels
    • Aso Y, Tayama K, Takanashi K, Inukai T, Takemura Y. Changes in skin blood flow in type 2 diabetes induced by prostacyclin: association with ankle brachial index and plasma thrombomodulin levels. Metabolism 2001;50:568-572
    • (2001) Metabolism , vol.50 , pp. 568-572
    • Aso, Y.1    Tayama, K.2    Takanashi, K.3    Inukai, T.4    Takemura, Y.5
  • 15
    • 0026512081 scopus 로고
    • The Zucker rat model of obesity, insulin resistance, hyperlipidemia, and renal injury
    • Kasiske BL, O'Donnell MP, Keane WF. The Zucker rat model of obesity, insulin resistance, hyperlipidemia, and renal injury. Hypertension 1992; 19(Suppl.):I110-I115
    • (1992) Hypertension , vol.19 , Issue.SUPPL.
    • Kasiske, B.L.1    O'Donnell, M.P.2    Keane, W.F.3
  • 16
    • 1642475578 scopus 로고
    • Abnormal oral glucose torelance in genetically obese (fa/fa) rats
    • Ionescu E, Sauter JF, Jeanrenaud B. Abnormal oral glucose torelance in genetically obese (fa/fa) rats. Am J Physiol 1985;248:E500-E506
    • (1985) Am J Physiol , vol.248
    • Ionescu, E.1    Sauter, J.F.2    Jeanrenaud, B.3
  • 17
    • 0024405776 scopus 로고
    • The Zucker fatty rat as a genetic model of obesity and hypertension
    • Kurtz TW, Morris RC, Pershadsingh HA. The Zucker fatty rat as a genetic model of obesity and hypertension. Hypertension 1989;13(Pt. 2):896-901
    • (1989) Hypertension , vol.13 , Issue.PART 2 , pp. 896-901
    • Kurtz, T.W.1    Morris, R.C.2    Pershadsingh, H.A.3
  • 18
    • 0035487317 scopus 로고    scopus 로고
    • Intramyocellular lipid is associated with resistance to in vivo insulin actions on glucose uptake, antilipolysis, and early insulin signaling pathways in human skeletal muscle
    • Virkamäki A, Korsheninnikova E, Seppälä-Lindroos A, Vehkavaara S, Goto T, Halavaara J, Häkkinen AM, Yki-Järvinen H. Intramyocellular lipid is associated with resistance to in vivo insulin actions on glucose uptake, antilipolysis, and early insulin signaling pathways in human skeletal muscle. Diabetes 2001;50:2337-2343
    • (2001) Diabetes , vol.50 , pp. 2337-2343
    • Virkamäki, A.1    Korsheninnikova, E.2    Seppälä-Lindroos, A.3    Vehkavaara, S.4    Goto, T.5    Halavaara, J.6    Häkkinen, A.M.7    Yki-Järvinen, H.8
  • 19
    • 15744403834 scopus 로고    scopus 로고
    • Age and muscle-type modulated role of intramyocellular lipids in the progression of insulin resistance in nondiabetic Zucker rats
    • Korach-André M, Gounarides J, Deacon R, Beil M, Sun D, Gao J, Laurent D. Age and muscle-type modulated role of intramyocellular lipids in the progression of insulin resistance in nondiabetic Zucker rats. Metabolism 2005;54:522-528
    • (2005) Metabolism , vol.54 , pp. 522-528
    • Korach-André, M.1    Gounarides, J.2    Deacon, R.3    Beil, M.4    Sun, D.5    Gao, J.6    Laurent, D.7
  • 22
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
    • Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 1997;389:610-614
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 23
    • 0038809142 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein 1 in obesity and insulin resistance
    • Sartipy P, Loskutoff DJ. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci U S A 2003;100:7265-7270
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7265-7270
    • Sartipy, P.1    Loskutoff, D.J.2
  • 25
    • 0033867239 scopus 로고    scopus 로고
    • Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression
    • Ding Y, Vaziri ND, Coulson R, Kamanna VS, Roh DD. Effects of simulated hyperglycemia, insulin, and glucagon on endothelial nitric oxide synthase expression. Am J Physiol Endocrinol Metab 2000;279:E11-E17
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Ding, Y.1    Vaziri, N.D.2    Coulson, R.3    Kamanna, V.S.4    Roh, D.D.5
  • 26
    • 34548419551 scopus 로고    scopus 로고
    • Vascular function in the metabolic syndrome and the effects on skeletal muscle perfusion: Lessons from the obese Zucker rat
    • Frisbee JC, Delp MD. Vascular function in the metabolic syndrome and the effects on skeletal muscle perfusion: lessons from the obese Zucker rat. Essays Biochem 2006;42:145-161
    • (2006) Essays Biochem , vol.42 , pp. 145-161
    • Frisbee, J.C.1    Delp, M.D.2
  • 27
    • 0031962949 scopus 로고    scopus 로고
    • Evidence for altered sensitivity of the nitric oxide/cGMP signalling cascade in insulin-resistant skeletal muscle
    • Young ME, Leighton B. Evidence for altered sensitivity of the nitric oxide/cGMP signalling cascade in insulin-resistant skeletal muscle. Biochem J 1998;329:73-79
    • (1998) Biochem J , vol.329 , pp. 73-79
    • Young, M.E.1    Leighton, B.2
  • 29
    • 0036067729 scopus 로고    scopus 로고
    • Beraprost sodium, prostacyclin analogue, attenuates glomerular hyperfiltration and glomerular macrophage infiltration by modulating ecNOS expression in diabetic rats
    • Yamashita T, Shikata K, Matsuda M, Okada S, Ogawa D, Sugimoto H, Wada J, Makino H. Beraprost sodium, prostacyclin analogue, attenuates glomerular hyperfiltration and glomerular macrophage infiltration by modulating ecNOS expression in diabetic rats. Diabetes Res Clin Pract 2002;57:149-161
    • (2002) Diabetes Res Clin Pract , vol.57 , pp. 149-161
    • Yamashita, T.1    Shikata, K.2    Matsuda, M.3    Okada, S.4    Ogawa, D.5    Sugimoto, H.6    Wada, J.7    Makino, H.8
  • 31
    • 0033794249 scopus 로고    scopus 로고
    • Effects of pioglitazone on promoting energy storage, not expenditure, in brown adipose tissue of obese fa/fa Zucker rats: Comparison to CL 316,243
    • Burkey BF, Dong M, Gagen K, Eckhardt M, Dragonas N, Chen W, Grosenstein P, Argentieri G, de Souza CJ. Effects of pioglitazone on promoting energy storage, not expenditure, in brown adipose tissue of obese fa/fa Zucker rats: comparison to CL 316,243. Metabolism 2000;49: 1301-1308
    • (2000) Metabolism , vol.49 , pp. 1301-1308
    • Burkey, B.F.1    Dong, M.2    Gagen, K.3    Eckhardt, M.4    Dragonas, N.5    Chen, W.6    Grosenstein, P.7    Argentieri, G.8    De Souza, C.J.9
  • 33
    • 46249129403 scopus 로고    scopus 로고
    • The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats
    • Schäfer A, Pfrang J, Neumüller J, Fiedler S, Ertl G, Bauersachs J. The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats. Br J Pharmacol 2008;154:1047-1054
    • (2008) Br J Pharmacol , vol.154 , pp. 1047-1054
    • Schäfer, A.1    Pfrang, J.2    Neumüller, J.3    Fiedler, S.4    Ertl, G.5    Bauersachs, J.6
  • 35
    • 0037008267 scopus 로고    scopus 로고
    • Amelioration by beraprost sodium, a prostacyclin analogue, of established renal dysfunction in rat glomerulonephritis model
    • Yamada M, Sasaki R, Sato N, Suzuki M, Tamura M, Matsushita T, Kurumatani H. Amelioration by beraprost sodium, a prostacyclin analogue, of established renal dysfunction in rat glomerulonephritis model. Eur J Pharmacol 2002;449:167-176
    • (2002) Eur J Pharmacol , vol.449 , pp. 167-176
    • Yamada, M.1    Sasaki, R.2    Sato, N.3    Suzuki, M.4    Tamura, M.5    Matsushita, T.6    Kurumatani, H.7
  • 36
    • 0026755248 scopus 로고
    • Coordinate control of lipolysis by prostaglandin E2 and prostacyclin in rat adipose tissue
    • Chatzipanteli K, Rudolph S, Axelrod L. Coordinate control of lipolysis by prostaglandin E2 and prostacyclin in rat adipose tissue. Diabetes 1992;41: 927-935
    • (1992) Diabetes , vol.41 , pp. 927-935
    • Chatzipanteli, K.1    Rudolph, S.2    Axelrod, L.3
  • 37
    • 37349112477 scopus 로고    scopus 로고
    • Molecular mechanisms of the antiproliferative effect of beraprost, a prostacyclin agonist, in murine vascular smooth muscle cells
    • Lin H, Lee JL, Hou HH, Chung CP, Hsu SP, Juan SH. Molecular mechanisms of the antiproliferative effect of beraprost, a prostacyclin agonist, in murine vascular smooth muscle cells. J Cell Physiol 2008;214:434-441
    • (2008) J Cell Physiol , vol.214 , pp. 434-441
    • Lin, H.1    Lee, J.L.2    Hou, H.H.3    Chung, C.P.4    Hsu, S.P.5    Juan, S.H.6
  • 38
    • 0028984805 scopus 로고
    • Use of prostaglandin I2 analog in treatment of massive hepatic necrosis associated with endothelial cell injury and diffuse sinusoidal fibrin deposition
    • Fujiwara K, Mochida S, Ohno A, Arai M, Matsui A, Masaki N, Hirata K, Tomiya T, Yamaoka M, Nagoshi S. Use of prostaglandin I2 analog in treatment of massive hepatic necrosis associated with endothelial cell injury and diffuse sinusoidal fibrin deposition. Dig Dis Sci 1995;40:41-47
    • (1995) Dig Dis Sci , vol.40 , pp. 41-47
    • Fujiwara, K.1    Mochida, S.2    Ohno, A.3    Arai, M.4    Matsui, A.5    Masaki, N.6    Hirata, K.7    Tomiya, T.8    Yamaoka, M.9    Nagoshi, S.10
  • 39
    • 32844463192 scopus 로고    scopus 로고
    • Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin
    • Li Z, Rodríguez-Iturbe B, Ni Z, Shahkarami A, Sepassi L, Vaziri ND. Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin. Kidney Int 2005;68:2766-2772
    • (2005) Kidney Int , vol.68 , pp. 2766-2772
    • Li, Z.1    Rodríguez-Iturbe, B.2    Ni, Z.3    Shahkarami, A.4    Sepassi, L.5    Vaziri, N.D.6
  • 40
    • 0026667091 scopus 로고
    • Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage
    • Baylis C, Mitruka B, Deng A. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J Clin Invest 1992;90:278-281
    • (1992) J Clin Invest , vol.90 , pp. 278-281
    • Baylis, C.1    Mitruka, B.2    Deng, A.3
  • 44
    • 58149149350 scopus 로고    scopus 로고
    • Diabetic patients and kidney protection: An attainable target
    • Barit D, Cooper M E. Diabetic patients and kidney protection: an attainable target. J Hypertens 2008;26:S3-S7
    • (2008) J Hypertens , vol.26
    • Barit, D.1    Cooper, M.E.2
  • 45
    • 59849087336 scopus 로고    scopus 로고
    • Protective role of angiotensin II subtype 2 receptor in blood pressure increase in obese Zucker rats
    • Siddiqui AH, Ali Q, Hussain T. Protective role of angiotensin II subtype 2 receptor in blood pressure increase in obese Zucker rats. Hypertension 2009;53:256-261
    • (2009) Hypertension , vol.53 , pp. 256-261
    • Siddiqui, A.H.1    Ali, Q.2    Hussain, T.3
  • 46
    • 45149118530 scopus 로고    scopus 로고
    • PPAR-alpha agonist fenofibrate induces renal CYP enzymes and reduces blood pressure and glomerular hypertrophy in Zucker diabetic fatty rats
    • Zhao X, Li LY. PPAR-alpha agonist fenofibrate induces renal CYP enzymes and reduces blood pressure and glomerular hypertrophy in Zucker diabetic fatty rats. Am J Nephrol 2008;28:598-606
    • (2008) Am J Nephrol , vol.28 , pp. 598-606
    • Zhao, X.1    Li, L.Y.2
  • 47
    • 0035430576 scopus 로고    scopus 로고
    • Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
    • de Souza CJ, Eckhardt M, Gagen K, Dong M, Chen W, Laurent D, Burkey BF. Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance. Diabetes 2001;50:1863-1871
    • (2001) Diabetes , vol.50 , pp. 1863-1871
    • De Souza, C.J.1    Eckhardt, M.2    Gagen, K.3    Dong, M.4    Chen, W.5    Laurent, D.6    Burkey, B.F.7
  • 48
    • 0031850906 scopus 로고    scopus 로고
    • Beginning insulin treatment of obese patients with evening 70/30 insulin plus glimepiride versus insulin alone
    • Glimepiride Combination Group
    • Riddle MC, Schneider J, Glimepiride Combination Group. Beginning insulin treatment of obese patients with evening 70/30 insulin plus glimepiride versus insulin alone. Diabetes Care 1998;21:1052-1057
    • (1998) Diabetes Care , vol.21 , pp. 1052-1057
    • Riddle, M.C.1    Schneider, J.2


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