Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase a regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet β cells

Pancreas

Volumn 35, Issue 3, 2007, Pages

  Kwan, Edwin P ^a   Gao, Xiaodong ^a   Leung, Yuk M ^a   Gaisano, Herbert Y ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

EPAC; Exocytosis; Fluorescence imaging; Insulin granules; PKA

Indexed keywords

8 (4 CHLOROPHENYLTHIO) 2' O METHYLADENOSINE CYCLIC AMP; ADENOSINE DERIVATIVE; ANTIPORTER; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CYCLIC AMP; FORSKOLIN; GLUCAGON LIKE PEPTIDE 1; N 6 BENZOYLADENOSINE CYCLIC AMP; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FUSION; CELL MEMBRANE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME SUBSTRATE; EPIFLUORESCENCE MICROSCOPY; EXOCYTOSIS; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SECRETORY GRANULE;

ANIMALS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; EXOCYTOSIS; FORSKOLIN; GLUCAGON-LIKE PEPTIDE 1; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INSULIN; ISLETS OF LANGERHANS; ISOQUINOLINES; MALE; MEMBRANE FUSION; MICROSCOPY, FLUORESCENCE; RATS; RATS, SPRAGUE-DAWLEY; SECOND MESSENGER SYSTEMS; SECRETORY VESICLES; SULFONAMIDES;

EID: 34748859183     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/mpa.0b013e318073d1c9     Document Type: Article

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