The impact of Ca 2+/calmodulin-dependent protein kinase II on insulin gene expression in MIN6 cells

Biochemical and Biophysical Research Communications

Volumn 421, Issue 4, 2012, Pages 801-807

  Suefuji, Mihoshi ^a   Furukawa, Noboru ^a   Matsumoto, Kazuya ^a,b   Oiso, Hiroshi ^a   Shimoda, Seiya ^a   Yoshinaga, Tomoaki ^a   Matsuyama, Rina ^a   Miyagawa, Katsutoshi ^a   Kondo, Tatsuya ^a   Kawashima, Junji ^a   Tsuruzoe, Kaku ^a,c   Araki, Eiichi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b Medical Juridical Person Eikikai New Amakusa Hospital   (Japan)

^c Amakusa City Sumoto Hospital   (Japan)

Author keywords

CaMKII 2; CREB; CREB binding protein; CREB Ser142; Insulin gene promoter; Phosphorylation

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ADENOSINE TRIPHOSPHATE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; GLUCOSE; INSULIN; SYNAPSIN I;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL MEMBRANE DEPOLARIZATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE OVEREXPRESSION; INSULIN SYNTHESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; UPREGULATION; WILD TYPE;

ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL LINE, TUMOR; CREB-BINDING PROTEIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOWN-REGULATION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; INSULIN; MICE; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; SERINE;

EID: 84861225810     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.04.091     Document Type: Article

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