Spatial and temporal regulation of Ca2+/calmodulin-dependent protein kinase II activity in developing neurons

Journal of Neuroscience

Volumn 22, Issue 16, 2002, Pages 7016-7026

  Menegon, Andrea ^a   Verderio, Claudia ^b   Leoni, Chiara ^a   Benfenati, Fabio ^c   Czernik, Andrew J ^d   Greengard, Paul ^d   Matteoli, Michela ^b   Valtorta, Flavia ^a,e  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

^d ROCKEFELLER UNIVERSITY   (United States)

^e SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

Hippocampal neurons; Neuronal differentiation; Phosphospecific antibodies; Protein phosphorylation; Synapse; Synapsin

Indexed keywords

PROTEIN KINASE (CALCIUM,CALMODULIN) II; SYNAPSIN I;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DEPOLARIZATION; EMBRYO; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBUNIT; HIPPOCAMPUS; NERVE CELL GROWTH; NERVE ENDING; NERVE FIBER; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; SYNAPTOGENESIS;

EID: 0037104729     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-16-07016.2002     Document Type: Article

References (44)

1. Banker G, Cowan W (1977) Rat hippocampal neurons in dispersed cell culture. Science 209:809-811.
2. Barria A, Muller D, Derkach V, Griffith LC, Soderling TR (1997) Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation. Science 276:2042-2045.
3. 2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I. Nature 359:417-420.
4. 2+/calmodulin-dependent protein kinase II. Brain Res Mol Brain Res 40:297-309.
5. Booher J, Sensenbrenner M (1972) Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask cultures. Neurobiology 2:97-105.
6. Braun AP, Schulman H (1995) The multifunctional calcium/calmodulin-dependent protein kinase: From form to function. Annu Rev Physiol 57:417-445.
7. Czernik AJ, Girault JA, Nairn AC, Chen J, Snyder G, Kebabian J, Greengard P (1991) Production of phosphorylation state-specific antibodies. Methods Enzymol 201:264-283.
8. Dzhura I, Wu Y, Colbran RJ, Balser JR, Anderson ME (2000) Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat Cell Biol 2:173-177.
9. Favre B, Turowski P, Hemmings BA (1997) Differential inhibition and posttranslational modification of protein phosphatase 1 and 2A in MCF7 cells treated with caliculin-A, okadaic acid, and tautomycin. J Biol Chem 272:13856-13863.
10. Gallo V, Suergiu R, Giovannini C, Levi G (1987) Glutamate receptor subtypes in cultured cerebellar neurons: Modulation of glutamate and gamma-aminobutyric acid release. J Neurochem 49:1801-1809.
11. 2+/calmodulin-dependent protein kinase II and postsynaptic density 95 for binding to the NR2A subunit of the NMDA receptor. J Neurosci 21:1501-1509.
12. Greengard P, Valtorta F, Czernik AJ, Benfenati F (1993) Synaptic vesicle phosphoproteins and regulation of synaptic function. Science 259:780-785.
13. 2+/calmodulin-dependent protein kinases. Annu Rev Biochem 61:559-601.
14. Harris MK (1999) Structure, development, and plasticity of dendritic spines. Curr Opin Neurobiol 9:343-348.
15. Janssens V, Goris J (2001) Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signaling. Biochem J 353:417-439.
16. 2+/calmodulin-dependent protein kinases in cultured rat hippocampal neurons. J Biol Chem 274:9061-9067.
17. 2+/calmodulin-dependent protein kinase. Proc Natl Acad Sci USA 81:945-949.
18. Kennedy M (2000) Signal-processing machines at the postsynaptic density. Science 290:750-754.
19. Kennedy MB, Bennett MK, Erondu NE (1983) Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase. Proc Natl Acad Sci USA 80:7357-7361.
20. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
21. 2+/calmodulin-dependent protein kinase II. Proc Natl Acad Sci USA 83:4253-4257.
22. Lisman J (1994) Tha CaM kinase II hypothesis for the storage of synaptic memory. Trends Neurosci 17:406-412.
23. Lisman J, Malenka RC, Nicoll RA, Malinow R (1997) Learning mechanisms: The case for CaMKII. Science 276:2001-2002.
24. Maletic-Savatic M, Koothan T, Malinow R (1998) Calcium-evoked dendritic exocytosis in cultured hippocampal neurons. Part II: Mediation by calcium/calmodulin-dependent protein kinase II. J Neurosci 18:6814-6821.
25. Mayford MJ, Wang ER, Kandel TJ, O'Dell TJ (1995) CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell 81:891-904.
26. 2+/calmodulin-dependent protein kinase II isozymic forms from rat forebrain and cerebellum. J Biol Chem 260:1696-1704.
27. Menegon A, Leoni C, Benfenati F, Valtorta F (1997) Tat protein from HIV-1 activates MAP kinase in granule neurons and glial cells from the rat cerebellum. Biochem Biophys Res Commun 238:800-805.
28. Menegon A, Dunlap DD, Castano F, Benfenati F, Czernik AJ, Greengard P, Valtorta F (2000) Use of phosphosynapsin I-specific antibodies for image analysis of signal transduction in single nerve terminals. J Cell Sci 113:3573-3582.
29. 2+-triggered molecular switch. Cell 44:861-870.
30. Pravettoni E, Bacci A, Coco S, Forbicini P, Matteoli M, Verderio C (2000) Different localizations and functions of L-type and N-type calcium channels during development of hippocampal neurons. Dev Biol 227:581-594.
31. Rongo C, Kaplan JM (1999) CaMKII regulates the density of central glutamatergic synapses in vivo. Nature 402:195-199.
32. 2+/calmodulin-dependent protein kinase II in cultures of hippocampal pyramidal neurons and astrocytes. J Neurosci 8:1039-1051.
33. Shen K, Meyer T (1999) Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulation. Science 284:162-166.
34. Soderling TR (2000) CaM-kinases: Modulators of synaptic plasticity. Curr Opin Neurobiol 10:375-380.
35. Stevens CF, Tonegawa S, Wang Y (1994) The role of calcium-calmodulin kinase II in three forms of synaptic plasticity. Curr Biol 4:687-693.
36. Strack S, Barban MA, Wadzinski BE, Colbran RJ (1997) Differential inactivation of postsynaptic density-associated and soluble Ca2+/calmodulin-dependent protein kinase II by protein phosphatases 1 and 2A. J Neurochem 68:2119-2128.
37. Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Natl Acad Sci USA 76:4350-4353.
38. Vaccaro P, Dente L, Onofri F, Zucconi A, Martinelli S, Valtorta F, Greengard P, Cesareni G, Benfenati F (1997) Epitope mapping on mammalian synapsins using phage display libraries. Brain Res Mol Brain Res 52:1-16.
39. Valtorta F, Iezzi N, Benfenati F, Lu B, Poo M-M, Greengard P (1995) Accelerated structural maturation induced by synapsin I at developing neuromuscular synapses of Xenopus laevis. Eur J Neurosci 7:261-270.
40. Verderio C, Coco S, Pravettoni E, Bacci A, Matteoli M (1999a) Synaptogenesis in hippocampal cultures. Cell Mol Life Sci 55:1448-1462.
41. Verderio C, Coco S, Bacci A, Rossetto O, De Camilli P, Montecucco C, Matteoli M (1999b) Tetanus toxin blocks the exocytosis of synaptic vesicles clustered at synapses but not of synaptic vesicles in isolated axons. J Neurosci 19:6723-6732.
42. Wu G-Y, Cline HT (1998) Stabilization of dendritic arbor structure in vivo by CaMKII. Science 279:222-226.
43. Wu G-Y, Malinow R, Cline HT (1996) Maturation of a central glutamatergic synapse. Science 274:972-976.
44. Zou D-J, Cline HT (1996) Expression of constitutively active CaMKII in target tissue modifies presynaptic axon arbor growth. Neuron 16:529-539.