Regulation of insulin secretion by overexpression of Ca2+/calmodulin-dependent protein kinase II in insulinoma MIN6 cells

Endocrinology

Volumn 141, Issue 7, 2000, Pages 2350-2360

  Tabuchi, Hirotaka ^a   Yamamoto, Hideyuki ^a   Matsumoto, Kazuya ^a   Ebihara, Kenji ^a   Takeuchi, Yusuke ^a   Fukunaga, Kohji ^a   Hiraoka, Hideji ^b   Sasaki, Yasuharu ^b   Shichiri, Motoaki ^a   Miyamoto, Eishichi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b ASAHI CHEMICAL INDUSTRY CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GLUCOSE; INSULIN; PROTEIN KINASE (CALCIUM,CALMODULIN) II; SYNAPSIN I; TOLBUTAMIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HORMONAL REGULATION; IMMUNOBLOTTING; INSULIN RELEASE; INSULINOMA; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 17744381763     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.7.7553     Document Type: Article

References (49)

1. 2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion
2. Control of cytosolic free calcium in cultured human pancreatic β-cells occurs by external calcium-dependent and independent mechanism
3. Voltage-dependent intracellular calcium release from mouse islets stimulated by glucose
4. 2+/calmodulin-dependent protein kinase II in neuronal regulation
5. 2+/calmodulin-dependent protein kinases
6. CaM kinase II: A protein kinase with extraordinary talents germane to insulin exocytosis
7. 2+/calmodulin-dependent protein kinase II and synapsin I-like protein in mouse insulinoma MIN6 cells
8. 2+/calmodulin-dependent protein kinase II in isolated rat pancreatic islets
9. Cyclosporin A stimulation of glucose-induced insulin secretion in MIN6 cells
10. 2+/calmodulin-dependent protein kinase in rat pancreatic islets
11. Presence and possible involvement of Ca/calmodulin dependent protein kinases in insulin release from the rat pancreatic β cell
12. A novel pancreatic β-cell isoform of calcium/calmodulin-dependent protein kinase (β3 isoform) contains a proline-rich tandem repeat In the association domain
13. 2+/calmodulin-dependent protein kinase II δ associated with insulin secretion vesicles
14. 2+/calmodulin and cyclic 3,5′-adenosine monophosphate control movement of secretory granules through protein phosphorylation/dephosphorylation in the pancreatic β-cell
15. 2+/calmodulin-dependent protein kinase II
16. Calcium/calmodulin-dependent protein kinase II
17. 2+/calmodulin-dependent protein kinases
18. Amino acid sequences surrounding the cAMP-dependent and calcium/calmodulin-dependent phosphorylation sites in rat and bovine synapsin I
19. Calcium-stimulated phosphorylation of MAP-2 in pancreatic β-cells is mediated by CaM kinase II
20. Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases
21. Phosphorylation of synaptic vesicle proteins: Modulation of the α-SNAP interaction with the core complex
22. 2+/calmodulin protein kinase II in synaptic vesicles
23. Structure and function of the synapsins
24. Cloning from insulmoma cells of synapsin I associated with insulin secretory granules
25. 2+-induced hydrophobic site on calmodulin: Application for purification of calmodulin by phenyl-sepharose affinity chromatography
26. 2+/calmodulin-dependent protein kinase II and protein kinase C by glutamate in cultured rat hippocampal neurons
27. 2+/calmodulin-dependent protein kinase II in rat brain and various tissues
28. 2+/calmodulin-dependent protein kinase II in rat cerebellar granule cells
29. Assays of protein kinase
30. 2+/calmodulin-dependent protein kinase II inhibits neurite outgrowth of PC12 cells
31. Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase
32. 2+/calmodulin-dependent protein kinase determined by molecular cloning
33. Molecular cloning of the cDNA encoding the third polypeptide (γ) of brain calmodulin-dependent protein kinase II
34. Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs
35. 2+/calmodulin-dependent protein-kinase II by inter- and intrasubunit-catalyzed autophosphorylations
36. Establishment of a pancreatic β cell line that retains glucose-inducible Insulin secretion: Special reference to expression of glucose transporter isoforms
37. Cyclosporin-Induced inhibition of insulin secretion in isolated rat islets and HIT cells
38. Immunoassay of insulin: Two antibody system
39. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
40. Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic β cells
41. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
42. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
43. 2+/calmodulin-dependent protein kinase isoforms in rat brain
44. Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II
45. Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions
46. The mitogen-activated prorein kinase pathway in rat islets of Langerhans: Studies on the regulation of insulin secretion
47. Coupling calcium to SNARE-mediated synaptic vesicle fusion
48. 2+ sensor for transmitter release at a central synapse
49. Localization and functional role of synaptotagmin III in insulin secretory vesicles in pancreatic β-cells