Dependence of insulin secretion from permeabilized pancreatic β-cells on the activation of Ca2+/calmodulin-dependent protein kinase II: A re-evaluation of inhibitor studies

Biochemical Pharmacology

Volumn 60, Issue 11, 2000, Pages 1655-1663

  Bhatt, Harshika S ^a   Conner, Barry P ^a   Prasanna, Ganesh ^a   Yorio, Thomas ^a   Easom, Richard A ^a  

^a UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

Calcium; Calmodulin; Exocytosis; Insulin secretion; Protein kinase; Protein phosphorylation

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; 2 [N (4 METHOXY BENZENESULFONYL)] AMINO N (4 CHLOROCINNAMYL) N METHYLBENZYLAMINE; AUTOCAMTIDE 2 RELATED INHIBITORY PEPTIDE; CALCIUM CALMODULIN KINASE INHIBITOR 281 302; KN 92; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INSULIN RELEASE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; BENZYLAMINES; BIOLOGICAL TRANSPORT; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; ENZYME ACTIVATION; ENZYME INHIBITORS; INSULIN; ISLETS OF LANGERHANS; MALE; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; SULFONAMIDES;

EID: 0034575679     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00483-4     Document Type: Article

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