Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection

PLoS Pathogens

Volumn 8, Issue 4, 2012, Pages

  Mock, David J ^a   Hollenbaugh, Joseph A ^a   Daddacha, Waaqo ^a   Overstreet, Michael G ^a   Lazarski, Chris A ^b   Fowell, Deborah J ^a   Kim, Baek ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b GENVEC INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; DEOXYNUCLEOSIDE TRIPHOSPHATE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MESSENGER RNA; NUCLEOSIDE TRIPHOSPHATE; RIBONUCLEOTIDE REDUCTASE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DEOXYRIBONUCLEOTIDE; RRM2B PROTEIN, HUMAN;

ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL COUNT; CELL DEATH; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELL SUBPOPULATION; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; LEISHMANIA; LEISHMANIASIS; MIXED INFECTION; MONOCYTE; NONHUMAN; S PHASE CELL CYCLE CHECKPOINT; VIRUS REPLICATION; BIOSYNTHESIS; CELL CYCLE S PHASE; FEMALE; GENE EXPRESSION REGULATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LEISHMANIA MAJOR; MACROPHAGE; MALE; METABOLISM; PARASITOLOGY; SKIN LEISHMANIASIS; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1; LEISHMANIA MAJOR;

CELL CYCLE PROTEINS; DEOXYRIBONUCLEOTIDES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, VIRAL; HIV INFECTIONS; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MACROPHAGES; MALE; MONOCYTES; RIBONUCLEOTIDE REDUCTASES; S PHASE;

EID: 84861214279     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002635     Document Type: Article

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