Enhanced hematopoietic activity accompanies parasite expansion in the spleen and bone marrow of mice infected with Leishmania donovani

Infection and Immunity

Volumn 68, Issue 4, 2000, Pages 1840-1848

  Cotterell, Sara E J ^a   Engwerda, Christian R ^a   Kaye, Paul M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; COLONY FORMING UNIT GM; CONTROLLED STUDY; FEMALE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; LEISHMANIA DONOVANI; LEISHMANIASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN;

ANIMALS; BLOOD; BONE MARROW; CELL COUNT; CHEMOKINES; COLONY-FORMING UNITS ASSAY; CYTOKINES; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MACROPHAGE INFLAMMATORY PROTEIN-1; MICE; MICE, INBRED BALB C; MICE, SCID; RNA, MESSENGER; SPLEEN; TIME FACTORS;

EID: 0034073438     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.4.1840-1848.2000     Document Type: Article

References (57)

1. Baker, R., P. Chiodini, and P. M. Kaye. 1999. Leishmaniasis, p. 212-234. In D. Geraint James and A. Zumla (ed.), The granulomatous disorders. Cambridge University Press, Cambridge, United Kingdom.
2. Behringer, D., V. Kresin, R. Henschler, R. Mertelsmann, and A. Lindemann. 1997. Cytokine and chemokine production by CD34+ haemopoietic progenitor cells: detection in single cells. Br. J. Haematol. 97:9-14.
3. Blackwell, J. M., C. Hale, M. B. Roberts, O. M. Ulczak, F. Y. Liew, and J. G. Howard. 1985. An H-11-linked gene has a parallel effect on Leishmania major and L. donovani infections in mice. Immunogenetics 21:385-395.
4. Bosma, G. C., R. P. Custer, and M. J. Bosma. 1983. A severe combined immunodeficiency mutation in the mouse. Nature 301:527-530.
5. Briddell, R. A., C. A. Hartley, K. A. Smith, and I. K. McNiece. 1993. Recombinant rat stem cell factor synergizes with recombinant human granulocyte colony-stimulating factor in vivo in mice to mobilize peripheral blood progenitor cells that have enhanced repopulating potential. Blood 82:1720-1723.
6. Broxmeyer, H. E., C. R. Mantel, and S. M. Aronica. 1997. Biology and mechanisms of action of synergistically stimulated myeloid progenitor cell proliferation and suppression by chemokines. Stem Cells 15:69-77.
7. Clark, B. R., J. T. Gallagher, and T. M. Dexter. 1992. Cell adhesion in the stromal regulation of haemopoiesis. Baillieres Clin. Haematol. 5:619-652.
8. Cotterell, S., C. Engwerda, and P. Kaye. Leishmania donovani infection of bone marrow stromal marcrophages selectively enhances myelopoiesis, by a mechanism involving GM-CSF and TNF-alpha. Blood, in press.
9. Cotterell, S. E., C. R. Engwerda, and P. M. Kaye. 1999. Leishmania donovani infection initiates T cell-independent chemokine responses, which are subsequently amplified in a T cell-independent manner. Eur. J. Immunol. 29: 203-214.
10. Crocker, P. R., and S. Gordon. 1985. Isolation and characterization of resident stromal macrophages and hematopoietic cell clusters from mouse bone marrow. J. Exp. Med. 162:993-1014.
11. Davies, E. V., A. M. Singleton, and J. M. Blackwell. 1988. Differences in Lsh gene control over systemic Leishmania major and Leishmania donovani or Leishmania mexicana mexicana infections are caused by differential targeting to infiltrating and resident liver macrophage populations. Infect. Immun. 56:1128-1134.
12. Dexter, T. M., T. D. Allen, and L. G. Lajtha. 1977. Conditions controlling the proliferation of haemopoietic stem cells in vitro. J. Cell. Physiol. 91:335-344.
13. Djoko-Tamnou, J., C. Leclerc, F. Modabber, and L. Chedid. 1981. Studies on visceral Leishmania tropica infection in BALB/c mice. I. Clinical features and cellular changes. Clin. Exp. Immunol. 46:493-498.
14. Dorshkind, K., G. M. Keller, R. A. Phillips, R. G. Miller, G. C. Bosma, M. O'Toole, and M. J. Bosma. 1984. Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease. J. Immunol. 132:1804-1808.
15. Engwerda, C. R., M. L. Murphy, S. E. Cotterell, S. C. Smelt, and P. M. Kaye. 1998. Neutralization of IL-12 demonstrates the existence of discrete organ-specific phases in the control of Leishmania donovani. Eur. J. Immunol. 28:669-680.
16. Engwerda, C. R., S. C. Smelt, and P. M. Kaye. 1996. An in vivo analysis of cytokine production during Leishmania donovani infection in seid mice. Exp. Parasitol. 84:195-202.
17. Feng, Z. Y., J. Louis, V. Kindler, T. Pedrazzini, J. F. Eliason, R. Behin, and P. Vassalli. 1988. Aggravation of experimental cutaneous leishmaniasis in mice by administration of interleukin 3. Eur. J. Immunol. 18:1245-1251.
18. Gao, J. L., T. A. Wynn, Y. Chang, E. J. Lee, H. E. Broxmeyer, S. Cooper, H. L. Tiffany, H. Westphal, J. Kwon-Chung, and P. M. Murphy. 1997. Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1. J. Exp. Med. 185:1959-1968.
19. Greil, J., B. Bodendorfer, M. Rollinghoff, and W. Solbach. 1988. Application of recombinant granulocyte-macrophage colony-stimulating factor has a detrimental effect in experimental murine leishmaniasis. Eur. J. Immunol. 18: 1527-1533.
20. Jackson, J. D., Y. Yan, M. J. Brunda, L. S. Kelsey, and J. E. Talmadge. 1995. Interleukin-12 enhances peripheral hematopoiesis in vivo. Blood 85:2371-2376.
21. Kaye, P. M., A. J. Curry, and J. M. Blackwell. 1991. Differential production of Th1- and Th2-derived cytokines does not determine the genetically controlled or vaccine-induced rate of cure in murine visceral leishmaniasis. J. Immunol. 146:2763-2770.
22. Laterveer, L., I. J. Lindley, M. S. Hamilton, R. Willemze, and W. E. Fibbe. 1995. Interleukin-8 induces rapid mobilization of hematopoietic stem cells with radioprotective capacity and long-term myelolymphoid repopulating ability. Blood 85:2269-2275.
23. Leclercq, V., M. Lebastard, Y. Belkaid, J. Louis, and G. Milon. 1996. The outcome of the parasitic process initiated by Leishmania infantum in laboratory mice: a tissue-dependent pattern controlled by the Lsh and MHC loci. J. Immunol. 157:4537-4545.
24. Lelchuk, R., R. Graveley, and F. Y. Liew. 1988. Susceptibility to murine cutaneous leishmaniasis correlates with the capacity to generate interleukin 3 in response to leishmania antigen in vitro. Cell Immunol. 111:66-76.
25. Marchal, G., and G. Milon. 1986. Control of hemopoiesis in mice by sensitized L3T4 + Lyt2-lymphocytes during infection with bacillus Calmette-Guerin. Proc. Natl. Acad. Sci. USA 83:3977-3981.
26. Marchal, G., and G. Milon. 1981. Decreased erythropoiesis: the origin of the BCG induced anaemia in mice. Br. J. Haematol. 48:551-560.
27. Marchal, G., and G. Milon. 1984. Numeration of DTH-mediating T lymphocytes in mice under optimal titration conditions. Ann. Immunol. (Paris). 135C:353-364.
28. Metcalf, D. 1991. Control of granulocytes and macrophages: molecular, cellular, and clinical aspects. Science 254:529-533.
29. Milon, G., G. Marchal, and M. Lebastard. 1984. BDG infection in mice: a model for in vivo analysis of T lymphocytes as regulators of haemopoiesis. Ann. Immunol. 135C:291-294.
30. Milon, G., P. Goossens, and G. Marchal. 1985. Role of T lymphocytes during murine BCG infection, p. 553-559. In R. van Furth (ed.), Mononuclear piagocytes - characteristics, physiology and function. Martinus Nijhoff Publishers, Boston, Mass.
31. Milon, G., M. Gheorghiu, M. Lagranderie, M. Lebastard, and G. Marchal. 1984. BCG-induced anaemia in mice: no direct effect of the growth of bacilli. Ann. Immunol. (Paris) 135C:195-204.
32. Miralles, G. D., M. Y. Stoeckle, D. F. McDermott, F. D. Finkelman, and H. W. Murray. 1994. Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis. Infect. Immun. 62:1058-1063.
33. Mirkovich, A. M., A. Galelli, A. C. Allison, and F. Z. Modabber. 1986. Increased myelopoiesis during Leishmania major infection in mice: generation of 'safe targets,' a possible way to evade the effector immune mechanism. Clin. Exp. Immunol. 64:1-7.
34. Molineux, G., Z. Pojda, and T. M. Dexter. 1990. A comparison of hematopoiesis in normal and splenectomized mice treated with granulocyte colony-stimulating factor. Blood 75:563-569.
35. Murray, H. W., J. S. Cervia, J. Hariprashad, A. P. Taylor, M. Y. Stoeckle, and H. Hockman. 1995. Effect of granulocyte-macrophage colony-stimulating factor in experimental visceral leishmaniasis. J. Clin. Investig. 95:1183-1192.
36. Neben, S., K. Marcus, and P. Mauch. 1993. Mobilization of hematopoietic stem and progenitor cell subpopulations from the marrow to the blood of mice following cyclophosphamide and/or granulocyte colony-stimulating factor. Blood 81:1960-1967.
37. Nilsson, S. K., G. J. Lieschke, C. C. Garcia-Wijnen, B. Williams, D. Tzelepis, G. Hodgson, D. Grail, A. R. Dunn, and I. Bertoncello. 1995. Granulocyte-macrophage colony-stimulating factor is not responsible for the correction of hematopoietic deficiencies in the maturing op/op mouse. Blood 86:66-72.
38. Nishinakamura, R., A. Miyajima, P. J. Mee, V. L. Tybulewicz, and R. Murray. 1996. Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 functions. Blood 88: 2458-2464.
39. O'Garra, A., G. Stapleton, V. Dhar, M. Pearce, J. Schumacher, H. Rugo, D. Barbis, A. Stall, J. Cupp, K. Moore, et al. 1990. Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10. Int. Immunol. 2:821-832.
40. Papayannopoulou, T., C. Craddock, B. Nakamoto, G. V. Priestley, and N. S. Wolf. 1995. The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen. Proc. Natl. Acad. Sci. USA 92:9647-9651.
41. Peterson, V. M., J. J. Adamovicz, T. B. Elliott, M. M. Moore, G. S. Madonna, W. E. Jackson, III, G. D. Ledney, and W. C. Gause. 1994. Gene expression of hematoregulatory cytokines is elevated endogenously after sublethal gamma irradiation and is differentially enhanced by therapeutic administration of biologic response modifiers. J. Immunol. 153:2321-2330.
42. Pojda, Z., G. Molineux, and T. M. Dexter. 1989. Effects of long-term in vivo treatment of mice with purified murine recombinant GM-CSF. Exp. Hematol. 17:1100-1104.
43. Pruijt, J. F., Y. van Kooyk, C. G. Figdor, I. J. Lindley, R. Willemze, and W. E. Fibbe. 1998. Anti-LFA-1 blocking antibodies prevent mobilization of hematopoietic progenitor cells induced by interleukin-8. Blood 91:4099-4105.
44. Quesenberry, P., E. McElrath, E. Buxton, E. Kittler, R. Crittendon, and D. Temeles. 1990. Constitutive production of multiple hemopoietic growth factors by murine Dexter stroma. Blood 76:161a.
45. Rhoades, E. R., A. M. Cooper, and I. M. Orme. 1995. Chemokine response in mice infected with Mycobacterium tuberculosis. Infect. Immun. 63:3871-3877.
46. Saha, B., H. Nanda-Roy, A. Pakrashi, R. N. Chakrabarti, and S. Roy. 1991. Immunobiological studies on experimental visceral leishmaniasis. I. Changes in lymphoid organs and their possible role in pathogenesis. Eur. J. Immunol. 21:577-581.
47. Simmons, P. J., J. P. Levesque, and A. C. Zannettino. 1997. Adhesion molecules in haemopoiesis. Baillieres Clin. Haematol. 10:485-505.
48. Smelt, S. C., C. R. Engwerda, M. McCrossen, and P. M. Kaye. 1997. Destruction of follicular dendritic cells during chronic visceral leishmaniasis. J. Immunol. 158:3813-3821.
49. Stauber, L. A. 1958. Host resistance to the Khartoum strain of Leishmania donovani. Rice Institute Pamphlet. 45:80-86.
50. Taswell, C. 1981. Limiting dilution assays for the determination of immuno-competent cell frequencies. I. Data analysis. J. Immunol. 126:1614-1619.
51. Testa, N. J., and T. M. Dexter. 1999. The regulation of haematopoietic cell production, p. 1-12. In L. V. A. Hoffbrand, S. M. Lewis, and E. G. D. Tuddenham, (ed.), Postgraduate hematology. Butterworth/Heinemann, Oxford, United Kingdom.
52. Valledor, A. F., F. E. Borras, M. Cullell-Young, and A. Celada. 1998. Transcription factors that regulate monocyte/macrophage differentiation. J. Leukoc. Biol. 63:405-417.
53. Vermeulen, M., F. Le Pesteur, M. C. Gagnerault, J. Y. Mary, F. Sainteny, and F. Lepault. 1998. Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells. Blood 92:894-900.
54. Weiss, L. 1989. Mechanisms of splenic control of murine malaria: cellular reactions of the spleen in lethal (strain 17XL) Plasmodium yoelii malaria in BALB/c mice, and the consequences of pre-infective splenectomy. Am. J. Trop. Med. Hyg. 41:144-160.
55. Wilson, M. E., M. Sandor, A. M. Blum, B. M. Young, A. Metwali, D. Elliott, R. G. Lynch, and J. V. Weinstock. 1996. Local suppression of IFN-gamma in hepatic granulomas correlates with tissue-specific replication of Leishmania chagasi. J. Immunol. 156:2231-2239.
56. Young, A. M., and C. Cheers. 1986. Colony-forming cells and colony-stimulating activity during listeriosis in genetically resistant or susceptible mice. Cell Immunol. 97:227-237.
57. Zhan, Y., G. J. Lieschke, D. Grail, A. R. Dunn, and C. Cheers. 1998. Essential roles for granulocyte-macrophage colony-stimulating factor (GM-CSF) and G-CSF in the sustained hematopoietic response of Listeria monocytogenes-infected mice. Blood 91:863-869.