Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication

Journal of Biological Chemistry

Volumn 277, Issue 46, 2002, Pages 44376-44384

  Angus, Steven P ^a   Wheeler, Linda J ^b   Ranmal, Sejal A ^a   Zhang, Xiaoping ^a   Markey, Michael P ^a   Mathews, Christopher K ^b   Knudsen, Erik S ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b OREGON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; ENZYMES; METABOLISM; METABOLITES;

TUMOR SUPPRESSORS;

TUMORS;

CYCLIN DEPENDENT KINASE; CYCLINE; DIHYDROFOLATE REDUCTASE; DNA; RIBONUCLEOTIDE REDUCTASE; THYMIDYLATE SYNTHASE;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; DNA REPLICATION; GENE DISRUPTION; METABOLIC REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINOBLASTOMA; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ADENOVIRIDAE; ANIMALS; CDC2-CDC28 KINASES; CELL CYCLE; CELL DIVISION; CELL LINE; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; DNA; FLOW CYTOMETRY; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RATS; RETINOBLASTOMA PROTEIN; S PHASE; TIME FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0346106146     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205911200     Document Type: Article

References (53)

1. Wang, J. Y., Knudsen, E. S., and Welch, P. J. (1994) Adv. Cancer Res. 64, 25-85
2. Sherr, C. J. (1996) Science 274, 1672-1677
3. Harbour, J. W., and Dean, D. C. (2000) Genes Dev. 14, 2393-2409
4. Bartek, J., Bartkova, J., and Lukas, J. (1997) Exp. Cell Res. 237, 1-6
5. Kaelin, W. G., Jr. (1997) Cancer Invest. 15, 243-254
6. Dyson, N. (1998) Genes Dev. 12, 2245-2262
7. Strobeck, M. W., Knudsen, K. E., Fribourg, A. F., DeCristofaro, M. F., Weissman, B. E., Imbalzano, A. N., and Knudsen, E. S. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7748-7753
8. Zhang, H. S., Gavin, M., Dahiya, A., Postigo, A. A., Ma, D., Luo, R. X., Harbour, J. W., and Dean, D. C. (2000) Cell 101, 79-89
9. Mittnacht, S. (1998) Curr. Opin. Genet. Dev. 8, 21-27
10. DeGregori, J., Kowalik, T., and Nevins, J. R. (1995) Mol. Cell. Biol. 15, 4215-4224
11. Ishida, S., Huang, E., Zuzan, H., Spang, R., Leone, G., West, M., and Nevins, J. R. (2001) Mol. Cell. Biol. 21, 4684-4699
12. Reed, S. I. (1997) Cancer Surv. 29, 7-23
13. Ohtsubo, M., Theodoras, A. M., Schumacher, J., Roberts, J. M., and Pagano, M. (1995) Mol. Cell. Biol. 15, 2612-2624
14. Kelly, T. J., and Brown, G. W. (2000) Annu. Rev. Biochem. 69, 829-880
15. Waga, S., and Stillman, B. (1998) Annu. Rev. Biochem. 67, 721-751
16. Sever-Chroneos, Z., Angus, S. P., Fribourg, A. F., Wan, H., Todorov, I., Knudsen, K. E., and Knudsen, E. S. (2001) Mol. Cell. Biol. 21, 4032-4045
17. Knudsen, K. E., Booth, D., Naderi, S., Sever-Chroneos, Z., Fribourg, A. F., Hunton, I. C., Feramisco, J. R., Wang, J. Y., and Knudsen, E. S. (2000) Mol. Cell. Biol. 20, 7751-7763
18. Petre, C. E., Wetherill, Y. B., Danielsen, M., and Knudsen, K. E. (2002) J. Biol. Chem. 277, 2207-2215
19. Angus, S. P., Fribourg, A. F., Markey, M. P., Williams, S. L., Horn, H. F., DeGregori, J., Kowalik, T. F., Fukasawa, K., and Knudsen, E. S. (2002) Exp. Cell Res. 276, 201-213
20. Knudsen, K. E., Arden, K. C., and Cavenee, W. K. (1998) J. Biol. Chem. 273, 20213-20222
21. Knudsen, E. S., Buckmaster, C., Chen, T. T., Feramisco, J. R., and Wang, J. Y. (1998) Genes Dev. 12, 2278-2292
22. Fukushima, M., Fujioka, A., Uchida, J., Nakagawa, F., and Takechi, T. (2001) Eur. J. Cancer 37, 1681-1687
23. Sargent, R. G., and Mathews, C. K. (1987) J. Biol. Chem. 262, 5546-5553
24. Sherman, P. A., and Fyfe, J. A. (1989) Anal. Biochem. 180, 222-226
25. Chew, Y. P., Ellis, M., Wilkie, S., and Mittnacht, S. (1998) Oncogene 17, 2177-2186
26. Lukas, J., Herzinger, T., Hansen, K., Moroni, M. C., Resnitzky, D., Helin, K., Reed, S. I., and Bartek, J. (1997) Genes Dev. 11, 1479-1492
27. Dimitrova, D. S., Todorov, I. T., Melendy, T., and Gilbert, D. M. (1999) J. Cell Biol. 146, 709-722
28. Schweitzer, B. I., Dicker, A. P., and Bertino, J. R. (1990) FASEB J. 4, 2441-2452
29. Bertino, J. R., Li, W. W., Lin, J., Trippett, T., Goker, E., Schweitzer, B., and Banerjee, D. (1992) Mt. Sinai J. Med. 59, 391-395
30. Mathews, C. K. (1993) Prog. Nucleic Acids Res. Mol. Biol. 44, 167-203
31. Elledge, S. J., Zhou, Z., and Allen, J. B. (1992) Trends Biochem. Sci. 17, 119-123
32. Reichard, P. (1988) Annu. Rev. Biochem. 57, 349-374
33. Reichard, P. (1993) Science 260, 1773-1777
34. Bruce, J. L., Hurford, R. K., Jr., Classon, M., Koh, J., and Dyson, N. (2000) Mol. Cell 6, 737-742
35. Lukas, J., Parry, D., Aagaard, L., Mann, D. J., Bartkova, J., Strauss, M., Peters, G., and Bartek, J. (1995) Nature 375, 503-506
36. Herrera, R. E., Sah, V. P., Williams, B. O., Makela, T. P., Weinberg, R. A., and Jacks, T. (1996) Mol. Cell. Biol. 16, 2402-2407
37. Hurford, R. K., Jr., Cobrinik, D., Lee, M. H., and Dyson, N. (1997) Genes Dev. 11, 1447-1463
38. Almasan, A., Yin, Y., Kelly, R. E., Lee, E. Y., Bradley, A., Li, W., Bertino, J. R., and Wahl, G. M. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5436-5440
39. Pinedo, H. M., and Peters, G. F. (1988) J. Clin. Oncol. 6, 1653-1664
40. Griffig, J., Koob, R., and Blakley, R. L. (1989) Cancer Res. 49, 6923-6928
41. Zhang, H. S., Postigo, A. A., and Dean, D. C. (1999) Cell 97, 53-61
42. Lukas, J., Sorensen, C. S., Lukas, C., Santoni-Rugiu, E., and Bartek, J. (1999) Oncogene 18, 3930-3935
43. Knudsen, K. E., Fribourg, A. F., Strobeck, M. W., Blanchard, J. M., and Knudsen, E. S. (1999) J. Biol. Chem. 274, 27632-27641
44. Bravo, R., and Macdonald-Bravo, H. (1985) EMBO J. 4, 655-661
45. Mathews, C. K., and Ji, J. (1992) Bioessays 14, 295-301
46. Leeds, J. M., Slabaugh, M. B., and Mathews, C. K. (1985) Mol. Cell. Biol. 5, 3443-3450
47. Collins, J. M. (1978) J. Biol. Chem. 253, 8570-8577
48. Slansky, J. E., and Farnham, P. J. (1996) Bioessays 18, 55-62
49. Dou, Q. P., Zhao, S., Levin, A. H., Wang, J., Helin, K., and Pardee, A. B. (1994) J. Biol. Chem. 269, 1306-1313
50. Wells, J., Boyd, K. E., Fry, C. J., Bartley, S. M., and Farnham, P. J. (2000) Mol. Cell. Biol. 20, 5797-5807
51. Li, W., Fan, J., Hochhauser, D., Banerjee, D., Zielinski, Z., Almasan, A., Yin, Y., Kelly, R., Wahl, G. M., and Bertino, J. R. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10436-10440
52. Zhao, X., Muller, E. G., and Rothstein, R. (1998) Mol. Cell 2, 329-340
53. Chabes, A., Domkin, V., and Thelander, L. (1999) J. Biol. Chem. 274, 36679-36683