Selective inhibition of biotin protein ligase from Staphylococcus aureus

Journal of Biological Chemistry

Volumn 287, Issue 21, 2012, Pages 17823-17832

  Soares Da Costa, Tatiana P ^a   Tieu, William ^a   Yap, Min Y ^b   Pendini, Nicole R ^a,b   Polyak, Steven W ^a   Pedersen, Daniel Sejer ^a   Morona, Renato ^a   Turnidge, John D ^a,c   Wallace, John C ^a   Wilce, Matthew C J ^b   Booker, Grant W ^a   Abell, Andrew D ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c WOMEN S AND CHILDREN S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

1 ,2 ,3-TRIAZOLES; ANTIBIOTIC CLASS; ANTIBIOTIC DISCOVERY; BACTERIAL ENZYMES; CHEMICAL CLASS; CLICK CHEMISTRY; CURRENT RESISTANCE; DRUG TARGETS; DRUG-RESISTANT BACTERIA; HIGH SELECTIVITY; HUMAN HOMOLOGUE; MAMMALIAN CELLS; MEDICINAL CHEMISTRY; METABOLIC ENZYMES; PHARMACOPHORES; PROTEIN LIGASE; S. AUREUS; SELECTIVE INHIBITION; STAPHYLOCOCCUS AUREUS;

ANTIBIOTICS; BACTERIA; NITROGEN COMPOUNDS; X RAY CRYSTALLOGRAPHY;

COENZYMES;

1,2,3 TRIAZOLE DERIVATIVE; ADENOSINE; BIOTIN; BIOTIN PROTEIN LIGASE; LIGASE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG BINDING; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; BIOTIN; CELL LINE; CLICK CHEMISTRY; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, BACTERIAL; ENZYME INHIBITORS; HUMANS; LIGASES; PROTEIN BINDING; STAPHYLOCOCCUS AUREUS; TRIAZOLES;

BACTERIA (MICROORGANISMS); MAMMALIA; STAPHYLOCOCCUS AUREUS;

EID: 84861207415     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.356576     Document Type: Article

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