Structural ordering of disordered ligand-binding loops of biotin protein ligase into active conformations as a consequence of dehydration

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Gupta, Vibha ^a   Gupta, Rakesh K ^a   Khare, Garima ^a   Salunke, Dinakar M ^b   Surolia, Avadhesha ^b   Tyagi, Anil K ^a  

^a UNIVERSITY OF DELHI   (India)

^b NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADENOSINE TRIPHOSPHATE; BACTERIAL ENZYME; BACTERIAL PROTEIN; BIOTIN; BIOTIN ACETYL COENZYME A CARBOXYLASE LIGASE; BIOTIN DERIVATIVE; LIGASE; UNCLASSIFIED DRUG; BIOTIN (ACETYL COA CARBOXYLASE)SYNTHETASE; BIOTIN-(ACETYL-COA CARBOXYLASE)SYNTHETASE; LIGAND; WATER;

ARTICLE; BIOTINYLATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME CONFORMATION; ENZYME SUBUNIT; HYDRATION; LIGAND BINDING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; SEQUENCE ALIGNMENT; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; X RAY DIFFRACTION;

MYCOBACTERIUM TUBERCULOSIS; PYROCOCCUS HORIKOSHII;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; BIOTIN; CARBON-NITROGEN LIGASES; CRYSTALLIZATION; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; WATER; X-RAY DIFFRACTION;

EID: 77950134712     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009222     Document Type: Article

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