Pseudomonas aeruginosa causes acute lung injury via the catalytic activity of the patatin-like phospholipase domain of ExoU

Critical Care Medicine

Volumn 32, Issue 11, 2004, Pages 2293-2299

  Pankhaniya, Ravi R ^a   Tamura, Miki ^a   Allmond, Leonard R ^a   Moriyama, Kiyoshi ^a   Ajayi, Temitayo ^a   Wiener Kronish, Jeanine P ^a   Sawa, Teiji ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute lung injury; Bacterial toxins; ExoU protein; Experimental animal models; Phospholipase A; Pseudomonas aeruginosa

Indexed keywords

BACTERIAL TOXIN; MUTANT PROTEIN; PHOSPHOLIPASE; PHOSPHOLIPASE A2; PROTEIN EXOU; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL TISSUE; ARTICLE; BACTEREMIA; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CATALYSIS; CAUSE OF DEATH; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; GRAM NEGATIVE INFECTION; LUNG ALVEOLUS EPITHELIUM; LUNG EDEMA; LUNG INFECTION; LUNG INJURY; MALE; MORTALITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PSEUDOMONAS AERUGINOSA; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

ACUTE DISEASE; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CYTOSOL; DISEASE MODELS, ANIMAL; EUKARYOTIC CELLS; IMMUNOBLOTTING; INFLAMMATION; LYSOPHOSPHOLIPASE; MALE; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PNEUMONIA, BACTERIAL; POINT MUTATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RESPIRATORY DISTRESS SYNDROME, ADULT; SEQUENCE ALIGNMENT; SURVIVAL RATE;

EID: 8544233545     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000145588.79063.07     Document Type: Article

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