Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: Protective effects of R-α-lipoic acid

Journal of Neuroscience Research

Volumn 84, Issue 3, 2006, Pages 647-654

  Cui, Xu ^a   Zuo, Pingping ^b   Zhang, Qing ^b   Li, Xuekun ^b   Hu, Yazhuo ^a   Long, Jiangang ^c   Packer, Lester ^d   Liu, Jiankang ^c,e,f  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^c Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; Cognitive dysfunction; Neurodegeneration; Neurogenesis; Oxidative damage; R lipoic acid

Indexed keywords

CASPASE 3; GALACTOSE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; THIOCTIC ACID;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL MIGRATION; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; DRUG EFFECT; DRUG EXPOSURE; HIPPOCAMPUS; MALE; MOUSE; NERVE DEGENERATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

AGING; ALZHEIMER DISEASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CASPASES; CELL DIFFERENTIATION; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; FREE RADICAL SCAVENGERS; FREE RADICALS; GALACTOSE; HIPPOCAMPUS; MALE; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; STEM CELLS; THIOCTIC ACID;

EID: 33746929523     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20899     Document Type: Article

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