Cell surface annexins regulate ADAM-mediated ectodomain shedding of proamphiregulin

Molecular Biology of the Cell

Volumn 23, Issue 10, 2012, Pages 1964-1975

  Nakayama, Hironao ^a,b,d   Fukuda, Shinji ^a   Inoue, Hirofumi ^a,b,c   Nishida Fukuda, Hisayo ^a   Shirakata, Yuji ^a   Hashimoto, Koji ^a   Higashiyama, Shigeki ^a,b,c  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JSPS   (Japan)

^c EHIME UNIVERSITY   (Japan)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM PROTEIN; AMPHIREGULIN; ANNEXIN; ANXA8 PROTEIN; ANXA9 PROTEIN; CALCIUM ION; EPIDERMAL GROWTH FACTOR RECEPTOR; LIPOCORTIN 2; UNCLASSIFIED DRUG;

ARTICLE; BIOTINYLATION; CELL MEMBRANE; CELL MIGRATION; CELL MOTILITY; CELL SURFACE; CONTROLLED STUDY; CROSS LINKING; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADAM PROTEINS; AMINO ACID SEQUENCE; ANNEXINS; CELL LINE, TUMOR; CELL MEMBRANE; CELL MOVEMENT; CULTURE MEDIA, CONDITIONED; GENE KNOCKDOWN TECHNIQUES; GLYCOPROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATINOCYTES; PHOSPHORYLATION; PRIMARY CELL CULTURE; PROTEIN BINDING; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; TETRADECANOYLPHORBOL ACETATE; TIME-LAPSE IMAGING; TRANSCRIPTIONAL ACTIVATION; ULTRAVIOLET RAYS;

EID: 84861151998     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E11-08-0683     Document Type: Article

References (51)

1. Bao J, Wolpowitz D, Role LW, Talmage DA (2003). Back signaling by the Nrg-1 intracellular domain. J Cell Biol 161, 1133-1141. (Pubitemid 36870174)
2. Baselga J, Swain SM (2009). Novel anticancer targets: revisiting ERBB2 and discovering ERBB3. Nat Rev Cancer 9, 463-475.
3. Chetcuti A, Margan SH, Russell P, Mann S, Millar DS, Clark SJ, Rogers J, Handelsman DJ, Dong Q (2001). Loss of annexin II heavy and light chains in prostate cancer and its precursors. Cancer Res 61, 6331-6334. (Pubitemid 32783232)
4. de Coupade C, Solito E, Levine JD (2003). Dexamethasone enhances interaction of endogenous annexin 1 with L-selectin and triggers shedding of L-selectin in the monocytic cell line U-937. Br J Pharmacol 140, 133-145. (Pubitemid 37175839)
5. Edwards DR, Handsley MM, Pennington CJ (2008). The ADAM metalloproteinases. Mol Aspects Med 29, 258-289.
6. Fatimathas L, Moss SE (2010). Annexins as disease modifiers. Histol Histopathol 25, 527-532.
7. Fredriksson S, Gullberg M, Jarvius J, Olsson C, Pietras K, Gustafsdottir SM, Ostman A, Landegren U (2002). Protein detection using proximitydependent DNA ligation assays. Nat Biotechnol 20, 473-477. (Pubitemid 34495933)
8. 2+ signalling to membrane dynamics. Nat Rev Mol Cell Biol 6, 449-461.
9. Gerke V, Moss SE (2002). Annexins: from structure to function. Physiol Rev 82, 331-371. (Pubitemid 34654456)
10. Goebeler V, Poeter M, Zeuschner D, Gerke V, Rescher U (2008). Annexin A8 regulates late endosome organization and function. Mol Biol Cell 19, 5267-5278.
11. Goishi K, Higashiyama S, Klagsbrun M, Nakano N, Umata T, Ishikawa M, Mekada E, Taniguchi N (1995). Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity. Mol Biol Cell 6, 967-980.
12. Grewal T, Enrich C (2009). Annexins-modulators of EGF receptor signalling and trafficking. Cell Signal 21, 847-858.
13. Gschwind A, Hart S, Fischer OM, Ullrich A (2003). TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. EMBO J 22, 2411-2421. (Pubitemid 36604980)
14. Hackel PO, Zwick E, Prenzel N, Ullrich A (1999). Epidermal growth factor receptors: critical mediators of multiple receptor pathways. Curr Opin Cell Biol 11, 184-189. (Pubitemid 29164032)
15. Hashimoto K, Higashiyama S, Asada H, Hashimura E, Kobayashi T, Sudo K, Nakagawa T, Damm D, Yoshikawa K, Taniguchi N (1994). Heparin-binding epidermal growth factor-like growth factor is an autocrine growth factor for human keratinocytes. J Biol Chem 269, 20060-20066.
16. Hieda M, Isokane M, Koizumi M, Higashi C, Tachibana T, Shudou M, Taguchi T, Hieda Y, Higashiyama S (2008). Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane. J Cell Biol 180, 763-769. (Pubitemid 351397776)
17. Higashiyama S, Iwabuki H, Morimoto C, Hieda M, Inoue H, Matsushita N (2008). Membrane-anchored growth factors, the epidermal growth factor family: beyond receptor ligands. Cancer Sci 99, 214-220. (Pubitemid 351228472)
18. Higashiyama S, Nanba D (2005). ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk. Biochim Biophys Acta 1751, 110-117. (Pubitemid 41033299)
19. Higashiyama S, Nanba D, Nakayama H, Inoue H, Fukuda S (2011). Ectodomain shedding and remnant peptide signalling of EGFRs and their ligands. J Biochem (Tokyo) 150, 15-22.
20. Hinkle CL, Sunnarborg SW, Loiselle D, Parker CE, Stevenson M, Russell WE, Lee DC (2004). Selective roles for tumor necrosis factor α-converting enzyme/ ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency. J Biol Chem 279, 24179-24188. (Pubitemid 38725278)
21. Igarashi T, Araki S, Mori H, Takeda S (2007). Crystal structures of catrocollastatin/ VAP2B reveal a dynamic, modular architecture of ADAM/adamalysin/ reprolysin family proteins. FEBS Lett 581, 2416-2422. (Pubitemid 46764699)
22. Isokane M, Hieda M, Hirakawa S, Shudou M, Nakashiro K, Hashimoto K, Hamakawa H, Higashiyama S (2008). Plasma-membrane-anchored growth factor pro-amphiregulin binds A-type lamin and regulates global transcription. J Cell Sci 121, 3608-3618.
23. Kahn J, Walcheck B, Migaki GI, Jutila MA, Kishimoto TK (1998). Calmodulin regulates L-selectin adhesion molecule expression and function through a protease-dependent mechanism. Cell 92, 809-818. (Pubitemid 28155319)
24. Kenny PA, Bissell MJ (2007). Targeting TACE-dependent EGFR ligand shedding in breast cancer. J Clin Invest 117, 337-345. (Pubitemid 46203962)
25. Kinugasa Y, Hieda M, Hori M, Higashiyama S (2007). The carboxyl-terminal fragment of pro-HB-EGF reverses Bcl6-mediated gene repression. J Biol Chem 282, 14797-14806. (Pubitemid 47093367)
26. Lee MJ, Yu GR, Yoo HJ, Kim JH, Yoon BI, Choi YK, Kim DG (2009). ANXA8 down-regulation by EGF-FOXO4 signaling is involved in cell scattering and tumor metastasis of cholangiocarcinoma. Gastroenterology 137, 1138-1150.
27. Ling Q, Jacovina AT, Deora A, Febbraio M, Simantov R, Silverstein RL, Hempstead B, Mark WH, Hajjar KA (2004). Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo. J Clin Invest 113, 38-48. (Pubitemid 38541630)
28. Liu JW, Shen JJ, Tanzillo-Swarts A, Bhatia B, Maldonado CM, Person MD, Lau SS, Tang DG (2003). Annexin II expression is reduced or lost in prostate cancer cells and its re-expression inhibits prostate cancer cell migration. Oncogene 22, 1475-1485. (Pubitemid 36390596)
29. Luetteke NC, Qiu TH, Peiffer RL, Oliver P, Smithies O, Lee DC (1993). TGFαdeficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice. Cell 73, 263-278. (Pubitemid 23123306)
30. Mayran N, Parton RG, Gruenberg J (2003). Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells. EMBO J 22, 3242-3253. (Pubitemid 36834855)
31. Moghal N, Sternberg PW (1999). Multiple positive and negative regulators of signaling by the EGF-receptor. Curr Opin Cell Biol 11, 190-196. (Pubitemid 29164033)
32. Moss SE, Morgan RO (2004). The annexins. Genome Biol 5, 219.
33. Mussunoor S, Murray GI (2008). The role of annexins in tumour development and progression. J Pathol 216, 131-140.
34. Nanba D, Mammoto A, Hashimoto K, Higashiyama S (2003). Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. J Cell Biol 163, 489-502. (Pubitemid 37429863)
35. Nishi E, Hiraoka Y, Yoshida K, Okawa K, Kita T (2006). Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-α-converting enzyme. J Biol Chem 281, 31164-31172. (Pubitemid 44582170)
36. Peschon JJ et al. (1998). An essential role for ectodomain shedding in mammalian development. Science 282, 1281-1284. (Pubitemid 28524483)
37. Rand JH (2000). Antiphospholipid antibody-mediated disruption of the annexin-V antithrombotic shield: a thrombogenic mechanism for the antiphospholipid syndrome. J Autoimmun 15, 107-111.
38. Sahin U, Weskamp G, Kelly K, Zhou HM, Higashiyama S, Peschon J, Hartmann D, Saftig P, Blobel CP (2004). Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands. J Cell Biol 164, 769-779. (Pubitemid 38282960)
39. Seo M, Lee MJ, Heo JH, Lee YI, Kim Y, Kim SY, Lee ES, Juhnn YS (2007). G protein βγ subunits augment UVB-induced apoptosis by stimulating the release of soluble heparin-binding epidermal growth factor from human keratinocytes. J Biol Chem 282, 24720-24730. (Pubitemid 47347554)
40. Shi W, Chen H, Sun J, Buckley S, Zhao J, Anderson KD, Williams RG, Warburton D (2003). TACE is required for fetal murine cardiac development and modeling. Dev Biol 261, 371-380. (Pubitemid 37108781)
41. Shirakata Y et al. (2005). Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing. J Cell Sci 118, 2363-2370. (Pubitemid 40873076)
42. Singh B, Schneider M, Knyazev P, Ullrich A (2009). UV-induced EGFR signal transactivation is dependent on proligand shedding by activated metalloproteases in skin cancer cell lines. Int J Cancer 124, 531-539.
43. Sternlicht MD, Sunnarborg SW, Kouros-Mehr H, Yu Y, Lee DC, Werb Z (2005). Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin. Development 132, 3923-3933. (Pubitemid 41410256)
44. Stoeck A, Shang L, Dempsey PJ (2010). Sequential and γ- secretasedependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth. J Cell Sci 123, 2319-2331.
45. Takeda S (2009). Three-dimensional domain architecture of the ADAM family proteinases. Semin Cell Dev Biol 20, 146-152.
46. Takeda S, Igarashi T, Mori H, Araki S (2006). Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold. EMBO J 25, 2388-2396. (Pubitemid 44012222)
47. Tokumaru S et al. (2000). Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healing. J Cell Biol 151, 209-220.
48. Uetani T, Nakayama H, Okayama H, Okura T, Higaki J, Inoue H, Higashiyama S (2009). Insufficiency of pro-heparin-binding epidermal growth factor-like growth factor shedding enhances hypoxic cell death in H9c2 cardiomyoblasts via the activation of caspase-3 and c-Jun N-terminal kinase. J Biol Chem 284, 12399-12409.
49. Walther A, Riehemann K, Gerke V (2000). A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR. Mol Cell 5, 831-840.
50. Yamazaki S et al. (2003). Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities. J Cell Biol 163, 469-475. (Pubitemid 37429861)
51. Yan Y, Shirakabe K, Werb Z (2002). The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G proteincoupled receptors. J Cell Biol 158, 221-226.