The carboxyl-terminal fragment of pro-HB-EGF reverses Bcl6-mediated gene repression

Journal of Biological Chemistry

Volumn 282, Issue 20, 2007, Pages 14797-14806

  Kinugasa, Yumi ^a,b   Hieda, Miki ^a   Hori, Masatsugu ^b   Higashiyama, Shigeki ^a,c  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASMIC DOMAINS; ECTODOMAIN SHEDDING; GENE REPRESSION; SIGNALING MOLECULES;

BINDING SITES; BIOLOGICAL MEMBRANES; CELLS; IMMUNOLOGY; MAMMALS; PROTEINS;

GENE EXPRESSION;

CYCLIN D2; GLUTATHIONE TRANSFERASE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; LUCIFERASE; PROTEIN BCL 6; PROTEIN PRECURSOR; BCL6 PROTEIN, HUMAN; CCND2 PROTEIN, HUMAN; CELL SURFACE RECEPTOR; CYCLINE; DIPHTHERIA TOXIN RECEPTOR; DNA BINDING PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; LIGAND; PEPTIDE FRAGMENT; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE INTERACTION; GENE REPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NUCLEAR IMPORT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN TRANSPORT; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ACTIVE TRANSPORT; CELL NUCLEUS; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

MAMMALIA;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL LINE, TUMOR; CELL NUCLEUS; CYCLINS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; LIGANDS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, CELL SURFACE; REPRESSOR PROTEINS;

EID: 34447529461     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611036200     Document Type: Article

References (43)

1. Higashiyama, S., and Nanba, D. (2005) Biochim. Biophys. Acta 1751, 110-117
2. Higashiyama, S., Abraham, J. A., Miller, J., Fiddes, J. C., and Klagsbrun, M. (1991) Science 251, 936-939
3. Higashiyama, S., Lau, K., Besner, G. E., Abraham, J. A., and Klagsbrun, M. (1992) J. Biol. Chem. 267, 6205-6212
4. Higashiyama, S., Iwamoto, R., Goishi, K., Raab, G., Taniguchi, N., Klagsbrun, M., and Mekada, E. (1995) J. Cell Biol. 128, 929-938
5. Iwamoto, R., Handa, K., and Mekada, E. (1999) J. Biol. Chem. 274, 25906-25912
6. Asakura, M., Kitakaze, M., Takashima, S., Liao, Y., Ishikura, F., Yoshinaka, T., Ohmoto, H., Node, K., Yoshino, K., Ishiguro, H., Asanuma, H., Sanada, S., Matsumura, Y., Takeda, H., Beppu, S., Tada, M., Hori, M., and Higashiyama, S. (2002) Nat. Med. 8, 35-40
7. Goishi, K., Higashiyama, S., Klagsbrun, M., Nakano, N., Umata, T., Ishikawa, M., Mekada, E., and Taniguchi, N. (1995) Mol. Biol. Cell 6, 967-980
8. Tokumaru, S., Higashiyama, S., Endo, T., Nakagawa, T., Miyagawa, J. I., Yamamori, K., Hanakawa, Y., Ohmoto, H., Yoshino, K., Shirakata, Y., Matsuzawa, Y., Hashimoto, K., and Taniguchi, N. (2000) J. Cell Biol. 151, 209-220
9. Izumi, Y., Hirata, M., Hasuwa, H., Iwamoto, R., Umata, T., Miyado, K., Tamai, Y., Kurisaki, T., Sehara-Fujisawa, A., Ohno, S., and Mekada, E. (1998) EMBO J. 17, 7260-7272
10. Lemjabbar, H., and Basbaum, C. (2002) Nat. Med. 8, 41-46
11. Sunnarborg, S. W., Hinkle, C. L., Stevenson, M., Russell, W. E., Raska, C. S., Peschon, J. J., Castner, B. J., Gerhart, M. J., Paxton, R. J., Black, R. A., and Lee, D. C. (2002) J. Biol. Chem. 277, 12838-12845
12. Yan, Y., Shirakabe, K., and Werb, Z. (2002) J. Cell Biol. 158, 221-226
13. Prenzel, N., Zwick, E., Daub, H., Leserer, M., Abraham, R., Wallasch, C., and Ullrich, A. (1999) Nature 402, 884-888
14. Chen, J. K., Capdevila, J., and Harris, R. C. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 6029-6034
15. Cussac, D., Schaak, S., Denis, C., and Paris, H. (2002) J. Biol. Chem. 277, 19882-19888
16. Shirakata, Y., Kimura, R., Nanba, D., Iwamoto, R., Tokumaru, S., Morimoto, C., Yokota, K., Nakamura, M., Sayama, K., Mekada, E., Higashiyama, S., and Hashimoto, K. (2005) J. Cell Sci. 118, 2363-2370
17. Nanba, D., Mammoto, A., Hashimoto, K., and Higashiyama, S. (2003) J. Cell Biol. 163, 489-502
18. Shaknovich, R., Yeyati, P. L., Ivins, S., Melnick, A., Lempert, C., Waxman, S., Zelent, A., and Licht, J. D. (1998) Mol. Cell. Biol. 18, 5533-5545
19. Yeyati, P. L., Shaknovich, R., Boterashvili, S., Li, J., Ball, H. J., Waxman, S., Nason-Burchenal, K., Dmitrovsky, E., Zelent, A., and Licht, J. D. (1999) Oncogene 18, 925-934
20. Dhordain, P., Albagli, O., Honore, N., Guidez, F., Lantoine, D., Schmid, M., The, H. D., Zelent, A., and Koken, M. H. (2000) Oncogene 19, 6240-6250
21. Baron, B. W., Nucifora, G., McCabe, N., Espinosa, R. 3rd., Le Beau, M. M., and McKeithan, T. W. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 5262-5266
22. Kerckaert, J. P., Deweindt, C., Tilly, H., Quief, S., Lecocq, G., and Bastard, C. (1993) Nat. Genet. 5, 66-70
23. Miki, T., Kawamata, N., Hirosawa, S., and Aoki, N. (1994) Blood 83, 26-32
24. Ye, B. H., Lista, F., Lo Coco, F., Knowles, D. M., Offit, K., Chaganti, R. S., and Dalla-Favera, R. (1993) Science 262, 747-750
25. Cattoretti, G., Chang, C. C., Cechova, K., Zhang, J., Ye, B. H., Falini, B., Louie, D. C., Offit, K., Chaganti, R. S., and Dalla-Favera, R. (1995) Blood 86, 45-53
26. Onizuka, T., Moriyama, M., Yamochi, T., Kuroda, T., Kazama, A., Kanazawa, N., Sato, K., Kato, T., Ota, H., and Mori, S. (1995) Blood 86, 28-37
27. Allman, D., Jain, A., Dent, A., Maile, R. R., Selvaggi, T., Kehry, M. R., and Staudt, L. M. (1996) Blood 87, 5257-5268
28. Huynh, K. D., and Bardwell, V. J. (1998) Oncogene 17, 2473-2484
29. Huynh, K. D., Fischle, W., Verdin, E., and Bardwell, V. J. (2000) Genes Dev. 14, 1810-1823
30. Dent, A. L., Vasanwala, F. H., and Toney, L. M. (2002) Crit. Rev. Oncol. Hematol. 41, 1-9
31. Shaffer, A. L., Yu, X., He, Y., Boldrick, J., Chan, E. P., and Staudt, L. M. (2000) Immunity 13, 199-212
32. Miyagawa, J., Higashiyama, S., Kawata, S., Inui, Y., Tamura, S., Yamamoto, K., Nishida, M., Nakamura, T., Yamashita, S., Matsuzawa, Y., and Taniguchi, N. (1995) J. Clin. Invest. 95, 404-411
33. Solvason, N., Wu, W. W., Kabra, N., Wu, X., Lees, E., and Howard, M. C. (1996) J. Exp. Med. 184, 407-417
34. Wolfe, S. A., Nekludova, L., and Pabo, C. O. (2000) Annu. Rev. Biophys. Biomol. Struct. 29, 183-212
35. Collins, T., Stone, J. R., and Williams, A. J. (2001) Mol. Cell. Biol. 21, 3609-3615
36. Dhordain, P., Lin, R. J., Quief, S., Lantoine, D., Kerckaert, J. P., Evans, R. M., and Albagli, O. (1998) Nucleic Acids Res. 26, 4645-4651
37. Moriyama, M., Yamochi, T., Semba, K., Akiyama, T., and Mori, S. (1997) Oncogene 14, 2465-2474
38. Niu, H., Ye, B. H., and Dalla-Favera, R. (1998) Genes Dev. 12, 1953-1961
39. Dent, A. L., Shaffer, A. L., Yu, X., Allman, D., and Staudt, L. M. (1997) Science 276, 589-592
40. Katz, A. M. (1990) N. Engl. J. Med. 322, 100-110
41. Busk, P. K., Bartkova, J., Strom, C. C., Wulf-Andersen, L., Hinrichsen, R., Christoffersen, T. E., Latella, L., Bartek, J., Haunso, S., and Sheikh, S. P. (2002) Cardiovasc. Res. 56, 64-75
42. Li, J. M., Poolman, R. A., and Brooks, G. (1998) Am. J. Physiol. 275, H814-H822
43. Zhong, W., Mao, S., Tobis, S., Angelis, E., Jordan, M. C., Roos, K. P., Fishbein, M. C., de Alboran, I. M., and MacLellan, W. R. (2006) EMBO J. 25, 3869-3879