4-O-carboxymethyl ascochlorin causes ER stress and induced autophagy in human hepatocellular carcinoma cells

Journal of Biological Chemistry

Volumn 287, Issue 19, 2012, Pages 15661-15671

  Kang, Jeong Han ^a   Chang, Young Chae ^b   Maurizi, Michael R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Catholic University of Daegu   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; CYTOTOXIC; ER STRESS; GEL ELECTROPHORESIS; HEPATOCELLULAR CARCINOMA CELL; HUMAN CANCER CELLS; HUMAN HEPATOCARCINOMA; MICROMOLAR CONCENTRATION; MURINE MODEL; NUCLEAR HORMONE RECEPTOR; PI3-KINASE; PROTEIN QUALITY CONTROL; STRESS-INDUCED; TRANSCRIPTIONAL REGULATOR; TYPE II;

CELL DEATH; CYTOTOXICITY; ELECTROPHORESIS; ENZYMES; GLUCOSE; MASS SPECTROMETRY; PROTEINS;

CELL CULTURE;

3 METHYLADENINE; 4 O CARBOXYMETHYL ASCOCHLORIN; AUTOPHAGY PROTEIN 5; BECLIN 1; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; GW 9962; LC3 II PROTEIN; PEPTIDES AND PROTEINS; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CARCINOMA CELL; CELL DEATH; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION;

APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; GLYCOLATES; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; PHAGOSOMES; PROTEOMICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; UNFOLDED PROTEIN RESPONSE;

MURINAE;

EID: 84860877843     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.358473     Document Type: Article

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