Pioglitazone reduces ER stress in the liver: Direct monitoring of in vivo ER stress using ER stress-activated indicator transgenic mice

Endocrine Journal

Volumn 56, Issue 9, 2009, Pages 1103-1111

  Yoshiuchi, Kazutomi ^a   Kaneto, Hideaki ^a   Matsuoka, Taka Aki ^a   Kasami, Ryuichi ^b   Kohno, Kenji ^c,d   Iwawaki, Takao ^a   Nakatani, Yoshihisa ^a   Yamasaki, Yoshimitsu ^a   Shimomura, Iichiro ^a   Matsuhisa, Munehide ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c Japan Science and Technology Agency   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

ER stress; Insulin resistance; Pioglitazone; Type 2 diabetes

Indexed keywords

FAT DROPLET; FATTY ACID; GREEN FLUORESCENT PROTEIN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PIOGLITAZONE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; ENDOPLASMIC RETICULUM STRESS; FATTY ACID BLOOD LEVEL; FLUORESCENCE; IN VIVO STUDY; INSULIN RESISTANCE; LIVER; MONITORING; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PROTEIN EXPRESSION; TRANSGENIC MOUSE; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; CELL SIZE; DIABETES MELLITUS, EXPERIMENTAL; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; GENES, REPORTER; HEAT-SHOCK PROTEINS; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; LIPID METABOLISM; LIPIDS; LIVER; MICE; MICE, TRANSGENIC; PPAR GAMMA; RANDOM ALLOCATION; RECEPTORS, PEPTIDE; STRESS, PHYSIOLOGICAL; THIAZOLIDINEDIONES; TIME FACTORS; TRANSCRIPTION FACTORS; VACUOLES;

EID: 74749102608     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K09E-140     Document Type: Article

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