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Volumn 93, Issue 1, 2012, Pages 26-34

Proteasome inhibitor treatment reduced fatty acid, triacylglycerol and cholesterol synthesis

Author keywords

Fatty acid; Proteasome inhibitor; Triacylglycerol and cholesterol synthesis

Indexed keywords

ACETYL COENZYME A; ACETYL COENZYME A CARBOXYLASE; ALCOHOL; APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; APOLIPOPROTEIN A4; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1 COMPLEMENTATION FACTOR; APOLIPOPROTEIN C3; BORTEZOMIB; CCAAT ENHANCER BINDING PROTEIN ALPHA; CHOLESTEROL; DIACYLGLYCEROL ACYLTRANSFERASE; FATTY ACID; FATTY ACID SYNTHASE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; LIPOPROTEIN LIPASE; LIPOPROTEIN RECEPTOR; MALONYL COENZYME A; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84860810068     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2012.03.006     Document Type: Article
Times cited : (30)

References (45)
  • 1
    • 77956858262 scopus 로고    scopus 로고
    • Enzymatic activity of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 11: upregulated in breast and cervical cancers
    • Epub 2010 Apr 2
    • Agarwal A.K., Garg A. Enzymatic activity of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 11: upregulated in breast and cervical cancers. Journal of Lipid Research 2010, 51(8):2143-2152. Epub 2010 Apr 2.
    • (2010) Journal of Lipid Research , vol.51 , Issue.8 , pp. 2143-2152
    • Agarwal, A.K.1    Garg, A.2
  • 6
    • 77952577051 scopus 로고    scopus 로고
    • The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats: the effect of feeding S-adenosylmethionine
    • Bardag-Gorce F., Li J., Oliva J., Lu S.C., French B.A., French S.W. The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats: the effect of feeding S-adenosylmethionine. Experimental and Molecular Pathology 2010, 88(3):380-387.
    • (2010) Experimental and Molecular Pathology , vol.88 , Issue.3 , pp. 380-387
    • Bardag-Gorce, F.1    Li, J.2    Oliva, J.3    Lu, S.C.4    French, B.A.5    French, S.W.6
  • 7
    • 78249268253 scopus 로고    scopus 로고
    • S-adenosylmethionine decreases the peak blood alcohol levels 3 h after an acute bolus of ethanol by inducing alcohol metabolizing enzymes in the liver
    • Bardag-Gorce F., Oliva J., Wong W., Fong S., Li J., French B.A., French S.W. S-adenosylmethionine decreases the peak blood alcohol levels 3 h after an acute bolus of ethanol by inducing alcohol metabolizing enzymes in the liver. Experimental and Molecular Pathology 2010, 89(3):217-221.
    • (2010) Experimental and Molecular Pathology , vol.89 , Issue.3 , pp. 217-221
    • Bardag-Gorce, F.1    Oliva, J.2    Wong, W.3    Fong, S.4    Li, J.5    French, B.A.6    French, S.W.7
  • 8
    • 78650710068 scopus 로고    scopus 로고
    • Proteasome inhibitor up regulates liver antioxidative enzymes in rat model of alcoholic liver disease
    • (Epub 2010 Oct 29, PMID: 21036165)
    • Bardag-Gorce F., Oliva J., Lin A., Li J., French B.A., French S.W. Proteasome inhibitor up regulates liver antioxidative enzymes in rat model of alcoholic liver disease. Experimental and Molecular Pathology 2011, 90(1):123-130. (Epub 2010 Oct 29, PMID: 21036165).
    • (2011) Experimental and Molecular Pathology , vol.90 , Issue.1 , pp. 123-130
    • Bardag-Gorce, F.1    Oliva, J.2    Lin, A.3    Li, J.4    French, B.A.5    French, S.W.6
  • 10
    • 2642586572 scopus 로고    scopus 로고
    • "Development of the proteasome inhibitor Velcade (Bortezomib)" by Julian Adams, Ph.D., and Michael Kauffman, M.D., Ph.D
    • Bold R. "Development of the proteasome inhibitor Velcade (Bortezomib)" by Julian Adams, Ph.D., and Michael Kauffman, M.D., Ph.D. Cancer Investigation 2004, 22(2):328-329.
    • (2004) Cancer Investigation , vol.22 , Issue.2 , pp. 328-329
    • Bold, R.1
  • 11
    • 0035793237 scopus 로고    scopus 로고
    • Chronic ingestion of ethanol stimulates lipogenic response in rat hepatocytes
    • Carrasco M.P., Marco C., Segovia J.L. Chronic ingestion of ethanol stimulates lipogenic response in rat hepatocytes. Life Sciences 2001, 68:1295-1304.
    • (2001) Life Sciences , vol.68 , pp. 1295-1304
    • Carrasco, M.P.1    Marco, C.2    Segovia, J.L.3
  • 13
    • 33751285781 scopus 로고    scopus 로고
    • Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity
    • Chen D., Cui Q.C., Yang H., Dou Q.P. Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity. Cancer Research 2006, 66(21):10425-10433.
    • (2006) Cancer Research , vol.66 , Issue.21 , pp. 10425-10433
    • Chen, D.1    Cui, Q.C.2    Yang, H.3    Dou, Q.P.4
  • 14
    • 66149129923 scopus 로고    scopus 로고
    • Taurine supplementation prevents ethanol-induced decrease in serum adiponectin and reduces hepatic steatosis in rats
    • Chen X., Sebastian B.M., Tang H., McMullen M.M., Axhemi A., Jacobsen D.W., Nagy L.E. Taurine supplementation prevents ethanol-induced decrease in serum adiponectin and reduces hepatic steatosis in rats. Hepatology 2009, 49(5):1554-1562.
    • (2009) Hepatology , vol.49 , Issue.5 , pp. 1554-1562
    • Chen, X.1    Sebastian, B.M.2    Tang, H.3    McMullen, M.M.4    Axhemi, A.5    Jacobsen, D.W.6    Nagy, L.E.7
  • 16
    • 48149090212 scopus 로고    scopus 로고
    • The value of proteasome inhibition in cancer. Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor?
    • Cvek B., Dvorak Z. The value of proteasome inhibition in cancer. Can the old drug, disulfiram, have a bright new future as a novel proteasome inhibitor?. Drug Discovery Today 2008, 13(15-16):716-722.
    • (2008) Drug Discovery Today , vol.13 , Issue.15-16 , pp. 716-722
    • Cvek, B.1    Dvorak, Z.2
  • 17
    • 0035138847 scopus 로고    scopus 로고
    • Intragastric ethanol infusion model for cellular and molecular studies of alcoholic liver disease
    • French S.W. Intragastric ethanol infusion model for cellular and molecular studies of alcoholic liver disease. Journal of Biomedical Science 2001, 8:20-27.
    • (2001) Journal of Biomedical Science , vol.8 , pp. 20-27
    • French, S.W.1
  • 18
    • 0026669452 scopus 로고
    • Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: a possible role for interleukin 6 in cancer cachexia
    • Greenberg A.S., Nordan R.P., McIntosh J., Calvo J.C., Scow R.O., Jablons D. Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes: a possible role for interleukin 6 in cancer cachexia. Cancer Research 1992, 52(15):4113-4116.
    • (1992) Cancer Research , vol.52 , Issue.15 , pp. 4113-4116
    • Greenberg, A.S.1    Nordan, R.P.2    McIntosh, J.3    Calvo, J.C.4    Scow, R.O.5    Jablons, D.6
  • 19
    • 33749253713 scopus 로고    scopus 로고
    • Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model
    • Ji C., Chan C., Kaplowitz N. Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model. Journal of Hepatology 2006, 45(5):717-724.
    • (2006) Journal of Hepatology , vol.45 , Issue.5 , pp. 717-724
    • Ji, C.1    Chan, C.2    Kaplowitz, N.3
  • 20
    • 33747615232 scopus 로고    scopus 로고
    • Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum
    • Kaplowitz N., Ji C. Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum. Journal of Gastroenterology and Hepatology 2006, 21(Suppl. 3):S7-S9.
    • (2006) Journal of Gastroenterology and Hepatology , vol.21 , Issue.SUPPL. 3
    • Kaplowitz, N.1    Ji, C.2
  • 21
    • 67649980707 scopus 로고    scopus 로고
    • Alcoholic liver disease and methionine metabolism
    • Kharbanda K.K. Alcoholic liver disease and methionine metabolism. Seminars in Liver Disease 2009, 29(2):155-165.
    • (2009) Seminars in Liver Disease , vol.29 , Issue.2 , pp. 155-165
    • Kharbanda, K.K.1
  • 22
    • 74149092293 scopus 로고    scopus 로고
    • Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis
    • Kim Y.W., Kim Y.M., Yang Y.M., Kim T.H., Hwang S.J., Lee J.R., Kim S.C., Kim S.G. Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis. Free Radical Biology & Medicine 2010, 48(4):567-578.
    • (2010) Free Radical Biology & Medicine , vol.48 , Issue.4 , pp. 567-578
    • Kim, Y.W.1    Kim, Y.M.2    Yang, Y.M.3    Kim, T.H.4    Hwang, S.J.5    Lee, J.R.6    Kim, S.C.7    Kim, S.G.8
  • 23
    • 65149084781 scopus 로고    scopus 로고
    • Management of alcoholic liver disease
    • Lucey M.R. Management of alcoholic liver disease. Clinics in Liver Disease 2009, 13(2):267-275.
    • (2009) Clinics in Liver Disease , vol.13 , Issue.2 , pp. 267-275
    • Lucey, M.R.1
  • 27
    • 77954908327 scopus 로고    scopus 로고
    • Triazolo compounds useful as diacylglycerol acyltransferase1 inhibitor - WO2009126624
    • Matsuda D., Tomoda H. Triazolo compounds useful as diacylglycerol acyltransferase1 inhibitor - WO2009126624. Expert Opinion on Therapeutic Patents 2010, 20(8):1097-1102.
    • (2010) Expert Opinion on Therapeutic Patents , vol.20 , Issue.8 , pp. 1097-1102
    • Matsuda, D.1    Tomoda, H.2
  • 30
    • 33744539521 scopus 로고    scopus 로고
    • Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
    • Obeng E.A., Carlson L.M., Gutman D.M., Harrington W.J., Lee K.P., Boise L.H. Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells. Blood 2006, 107(12):4907-4916.
    • (2006) Blood , vol.107 , Issue.12 , pp. 4907-4916
    • Obeng, E.A.1    Carlson, L.M.2    Gutman, D.M.3    Harrington, W.J.4    Lee, K.P.5    Boise, L.H.6
  • 36
    • 63449098685 scopus 로고    scopus 로고
    • Mechanisms targeting apolipoprotein B100 to proteasomal degradation: evidence that degradation is initiated by BiP binding at the N terminus and the formation of a p97 complex at the C terminus
    • Epub 2009 Jan 22
    • Rutledge A.C., Qiu W., Zhang R., Kohen-Avramoglu R., Nemat-Gorgani N., Adeli K. Mechanisms targeting apolipoprotein B100 to proteasomal degradation: evidence that degradation is initiated by BiP binding at the N terminus and the formation of a p97 complex at the C terminus. Arteriosclerosis, Thrombosis, and Vascular Biology 2009, 29(4):579-585. Epub 2009 Jan 22.
    • (2009) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.29 , Issue.4 , pp. 579-585
    • Rutledge, A.C.1    Qiu, W.2    Zhang, R.3    Kohen-Avramoglu, R.4    Nemat-Gorgani, N.5    Adeli, K.6
  • 37
    • 74849136799 scopus 로고    scopus 로고
    • Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia
    • Rzymski T., Milani M., Singleton D.C., Harris A.L. Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia. Cell Cycle 2009, 8(23):3838-3847.
    • (2009) Cell Cycle , vol.8 , Issue.23 , pp. 3838-3847
    • Rzymski, T.1    Milani, M.2    Singleton, D.C.3    Harris, A.L.4
  • 38
    • 40149088797 scopus 로고    scopus 로고
    • The blind men 'see' the elephant-the many faces of fatty liver disease
    • Sanal M.G. The blind men 'see' the elephant-the many faces of fatty liver disease. World Journal of Gastroenterology 2008, 14(6):831-844.
    • (2008) World Journal of Gastroenterology , vol.14 , Issue.6 , pp. 831-844
    • Sanal, M.G.1
  • 39
  • 41
  • 42
    • 78651112673 scopus 로고    scopus 로고
    • A novel coenzyme A:diacylglycerol acyltransferase 1 inhibitor stimulates lipid metabolism in muscle and lowers weight in animal models of obesity
    • Epub 2010 Oct 29
    • Yamamoto T., Yamaguchi H., Miki H., Kitamura S., Nakada Y., Aicher T.D., Pratt S.A., Kato K. A novel coenzyme A:diacylglycerol acyltransferase 1 inhibitor stimulates lipid metabolism in muscle and lowers weight in animal models of obesity. European Journal of Pharmacology 2011, 650(2-3):663-672. Epub 2010 Oct 29.
    • (2011) European Journal of Pharmacology , vol.650 , Issue.2-3 , pp. 663-672
    • Yamamoto, T.1    Yamaguchi, H.2    Miki, H.3    Kitamura, S.4    Nakada, Y.5    Aicher, T.D.6    Pratt, S.A.7    Kato, K.8
  • 43
    • 12744267804 scopus 로고    scopus 로고
    • Molecular mechanisms of alcoholic fatty liver: role of sterol regulatory element-binding proteins
    • You M., Crabb D.W. Molecular mechanisms of alcoholic fatty liver: role of sterol regulatory element-binding proteins. Alcohol 2004, 34:39-43.
    • (2004) Alcohol , vol.34 , pp. 39-43
    • You, M.1    Crabb, D.W.2
  • 44
    • 0037047284 scopus 로고    scopus 로고
    • Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)
    • You M., Fischer M., Deeg M.A., Crabb D.W. Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP). The Journal of Biological Chemistry 2002, 277:29342-29347.
    • (2002) The Journal of Biological Chemistry , vol.277 , pp. 29342-29347
    • You, M.1    Fischer, M.2    Deeg, M.A.3    Crabb, D.W.4
  • 45
    • 9644290860 scopus 로고    scopus 로고
    • The role of AMP-activated protein kinase in the action of ethanol in the liver
    • You M., Matsumoto M., Pacold C.M., Cho W.K., Crabb D.W. The role of AMP-activated protein kinase in the action of ethanol in the liver. Gastroenterology 2004, 127:1798-1808.
    • (2004) Gastroenterology , vol.127 , pp. 1798-1808
    • You, M.1    Matsumoto, M.2    Pacold, C.M.3    Cho, W.K.4    Crabb, D.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.