Gene expression patterns of the liver in response to alcohol: In vivo and in vitro models compared

Experimental and Molecular Pathology

Volumn 80, Issue 3, 2006, Pages 241-251

  Bardag Gorce, Fawzia ^a   French, Barbara A ^a   Dedes, Jennifer ^a   Li, Jun ^a   French, Samuel W ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; INITIATION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA;

ALCOHOL BLOOD LEVEL; ALCOHOL LIVER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GENE EXPRESSION; GLYCOSYLATION; HUMAN; HUMAN CELL; MALE; MITOCHONDRION; NONHUMAN; PATHOGENESIS; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DISEASE MODELS, ANIMAL; ETHANOL; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEPATOCYTES; HUMANS; IN SITU HYBRIDIZATION; LIVER; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, WISTAR;

ANIMALIA;

EID: 33646526030     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2005.12.006     Document Type: Article

References (22)

1. Bardag-Gorce F., French B.A., Li J., Riley N.E., Yuan Q.X., Reitz R., Cai Y., Wan Y.-J.Y., and French S.W. The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats fed ethanol intragastrically. Gastroenterology 123 (2002) 325-335
2. Caro A.A., and Cederbaum A.I. Synergistic toxicity of iron and arachidonic acid in HepG2 cells over expressing CYP2E1. Mol. Pharmacol. 60 (2001) 742-752
3. Caro A.A., and Cederbaum A.I. Oxidative stress, toxicology and pharmacology of CYP2E1. Ann. Rev. Pharmacol. Toxicol. 44 (2004) 27-42
4. Chen J., Zhou Y., Mueller-Steiner S., Chen L.F., Kwon H., Yi S., Mucke L., and Gan L. SIRT 1 protects against microglia-dependent beta amyloid toxicity through inhibiting NF-kappa B signaling. J. Biol. Chem. 280 (2005) 40364-40374
5. Chen W.Y., Wang D.H., Yen R.C., Luo J., Gu W., and Baylin S.B. Tumor suppressor H1C1 directly regulates SIRT 1 to modulate p53-dependent DNA-damage responses. Cell 123 (2005) 437-448
6. French B.A., Dedes J., Bardag-Gorce F., Li S., Wilson L., Fu P., Nan L., and French S.W. Microarray analysis of gene expression in the liver during the urinary ethanol cycle in rats fed ethanol intragastrically at a constant rate. Exp. Mol. Pathol. 79 (2005) 87-94
7. Fulco M., Schiltz R.L., Iezzi S., King M.T., Zhao P., Kashiwaya Y., Hoffman E., Veech R.L., and Sartorelli V. Sir 2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol. Cell 12 (2003) 51-62
8. Hisahara S., Chiba S., Matsumoto H., and Horio Y. Transcriptional regulation of neuronal genes and its effect on neural functions: NAD-dependent histone deacetylase SIRT 1 (SirZa). J. Pharmacol. Sci. 98 (2005) 200-204
9. Kobayashi Y., Furukawa-Hibi Y., Chen C., Horio Y., Isobe K., Ikeda K., and Motoyama N. SIRT 1 is a critical regulator of FOXO-mediated transcription in response to oxidative stress. Int. J. Mol. Med. 16 (2005) 237-243
10. Lakshman M.R., Rao M.N., and Marmillot P. Alcohol and molecular regulation of protein glycosylation and function. Alcohol 19 3 (1999) 239-247 (Nov)
11. Landberg E., Pahlsson P., Lundblad A., Arnetorp A., and Jeppsson J.O. Carbohydrate composition of serum transferrin isoforms from patients with high alcohol consumption. Biochem. Biophys. Res. Commun. 210 2 (1995) 267-274 (May 16)
12. Li J., Nguyen V., French B.A., Parlow A.F., Su G.L., Fu P., Yuan Q.X., and French S.W. Mechanism of the cyclic pattern in urinary ethanol levels in rats fed ethanol. The role of the hypothalamic-pituitary-thyroid axis. Am. J. Physiol. 279 (2000) G118-G125
13. Li J., French B.A., Fu P., Bardag-Gorce F., and French S.W. Mechanism of alcohol cyclic pattern: role of catecholamines. Am. J. Physiol.: Gastrointest. Liver Physiol. 285 (2003) G442-G448
14. Li J., French B.A., Fu P., Bardag-Gorce F., and French S.W. Catecholamines are involved in the mechanism of the urinary alcohol level cycle in rats fed ethanol intragastrically at a constant rate. Life Sci. 75 (2004) 3043-3051
15. Li J., French B., Wu Y., Ventatesh R., Montgomery R., Bardag-Gorce F., Kitto J., and French S.W. Liver hypoxia [and lack of recovery after reperfusion at high] blood alcohol levels [in the intragastric feeding model of alcoholic liver disease. Exp. Mol. Pathol. 77 (2004) 184-192
16. Li J., Fu P., French B.A., and French S.W. The effect of rotenone on the urinary ethanol cycle in rats fed ethanol intragastrically. Exp. Mol. Pathol. 77 (2004) 210-213
17. Li J., French B.A., Nan L., Fu P., and French S.W. Uncoupling of oxidative phosphorylation prevents the urinary alcohol level cycling by feeding ethanol continuously at a constant rate. Exp. Mol. Pathol. 78 (2005) 228-232
18. Lu S.C., and Mato J.M. Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer. Alcohol 35 (2005) 227-234
19. Luo J., Nikolaeu A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., and Gu W. Negative control of p53 by Sir 2 alpha promotes cell survival under stress. Cell 107 (2001) 137-148
20. Mann A.C., Record C.O., Self C.H., and Turner G.A. Monosaccharide composition of haptoglobin in liver diseases and alcohol abuse: large changes in glycosylation associated with alcoholic liver disease. Clin. Chim. Acta 227 1-2 (1994) 69-78 (Jun)
21. Park P.-H., Lim R.W., and Shukla S.D. Involvement of histone acetyltransferase (HAT) in ethanol-induced acetylation of histone H3 in hepatocytes: potential mechanism for gene expression. Am. J. Physiol. 1: Gastrointest. Liver Physiol. 289 (2005) G1124-G1136
22. Sakuravi K., and Cederbaum A.I. Oxidative stress and cytotoxicity induced by ferric-nitrilotriacetate in HepG2 cells that express cytochrome P450 2E1. Mol. Pharmacol. 54 (1998) 1024-1035