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Volumn 213, Issue 1, 2012, Pages 77-87

Testosterone modulates platelet aggregation and endothelial cell growth through nitric oxide pathway

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CALCIUM; CHELERYTHRINE; DNA; FLUTAMIDE; MITOGEN ACTIVATED PROTEIN KINASE; N NITRO LEVO ARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PROTEIN KINASE C; TESTOSTERONE; UNCLASSIFIED DRUG; VERAPAMIL; ANDROGEN; BENZOPHENANTHRIDINE DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; FLAVONOID;

EID: 84860792205     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-11-0441     Document Type: Article
Times cited : (57)

References (48)
  • 1
    • 0033840497 scopus 로고    scopus 로고
    • Endothelial cells in culture: a model for studying vascular functions
    • Bachetti T & Morbidelli L 2000 Endothelial cells in culture: a model for studying vascular functions. Pharmacological Research 42 9-19.
    • (2000) Pharmacological Research , vol.42 , pp. 9-19
    • Bachetti, T.1    Morbidelli, L.2
  • 2
    • 0031054463 scopus 로고    scopus 로고
    • Nitric oxide synthase: role in genesis of vascular disease
    • Cooke JP & Dzau VJ 1997 Nitric oxide synthase: role in genesis of vascular disease. Annual Review of Medicine 48 489-509.
    • (1997) Annual Review of Medicine , vol.48 , pp. 489-509
    • Cooke, J.P.1    Dzau, V.J.2
  • 9
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski RJ, Palmer RM & Moncada S 1986 Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320 454-456.
    • (1986) Nature , vol.320 , pp. 454-456
    • Gryglewski, R.J.1    Palmer, R.M.2    Moncada, S.3
  • 10
    • 34547095758 scopus 로고    scopus 로고
    • Non genomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signalling American Journal of Physiology
    • Han G, Ma H, Chintala R, Miyake K, Fulton DJ, Barman SA & White RE 2007 Non genomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signalling. American Journal of Physiology. Heart and Circulatory Physiology 293 H314-H321.
    • (2007) Heart and Circulatory Physiology , vol.293
    • Han, G.1    Ma, H.2    Chintala, R.3    Miyake, K.4    Fulton, D.J.5    Barman, S.A.6    White, R.E.7
  • 13
    • 0024706628 scopus 로고
    • Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein
    • Ignarro LJ 1989 Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circulation Research 65 1-21.
    • (1989) Circulation Research , vol.65 , pp. 1-21
    • Ignarro, L.J.1
  • 15
    • 4344684088 scopus 로고    scopus 로고
    • Gonadal hormones and frontocortical expression of vascular endothelial growth factor in male stroke-prone, spontaneously hypertensive rats, a model for attention-deficit/hyperactivity disorder
    • Jesmin S, Togashi H, Sakuma I, Mowa CN, Ueno K, Yamaguchi T, Yoshioka M & Kitabatake A 2004 Gonadal hormones and frontocortical expression of vascular endothelial growth factor in male stroke-prone, spontaneously hypertensive rats, a model for attention-deficit/hyperactivity disorder. Endocrinology 145 4330-4343.
    • (2004) Endocrinology , vol.145 , pp. 4330-4343
    • Jesmin, S.1    Togashi, H.2    Sakuma, I.3    Mowa, C.N.4    Ueno, K.5    Yamaguchi, T.6    Yoshioka, M.7    Kitabatake, A.8
  • 17
    • 4043174113 scopus 로고    scopus 로고
    • Testosterone-induced coronary vasodilatation occurs via a non-genomic mechanism: evidence of a direct calcium antagonism action
    • Jones RD, English KM, Jones TH & Channer KS 2004 Testosterone-induced coronary vasodilatation occurs via a non-genomic mechanism: evidence of a direct calcium antagonism action. Clinical Science 107 149-158.
    • (2004) Clinical Science , vol.107 , pp. 149-158
    • Jones, R.D.1    English, K.M.2    Jones, T.H.3    Channer, K.S.4
  • 18
    • 0028566361 scopus 로고
    • Regulation of inducible nitric oxide synthase gene by interleukin-1 beta in rat vascular endothelial cells
    • Kanno K, Hirata Y, Imai T, Iwashina M & Marumo F 1994 Regulation of inducible nitric oxide synthase gene by interleukin-1 beta in rat vascular endothelial cells. American Journal of Physiology 36 H2318-H2324.
    • (1994) American Journal of Physiology , vol.36
    • Kanno, K.1    Hirata, Y.2    Imai, T.3    Iwashina, M.4    Marumo, F.5
  • 19
    • 0032583180 scopus 로고    scopus 로고
    • High-affinity arginine transport of bovine aortic endothelial cells is impaired by lysophosphatidylcholine
    • Kikuta K, Sawamura T, Miwa S, Hashimoto N & Masaki T 1998 High-affinity arginine transport of bovine aortic endothelial cells is impaired by lysophosphatidylcholine. Circulation Research 83 1088-1096.
    • (1998) Circulation Research , vol.83 , pp. 1088-1096
    • Kikuta, K.1    Sawamura, T.2    Miwa, S.3    Hashimoto, N.4    Masaki, T.5
  • 20
    • 46749155783 scopus 로고    scopus 로고
    • Testosterone and dihydrotestosterone inhibit gallbladder motility through multiple signalling pathways
    • Kline LW & Karpinski E 2008 Testosterone and dihydrotestosterone inhibit gallbladder motility through multiple signalling pathways. Steroids 73 1174-1180.
    • (2008) Steroids , vol.73 , pp. 1174-1180
    • Kline, L.W.1    Karpinski, E.2
  • 22
    • 34447309302 scopus 로고    scopus 로고
    • Sex hormone replacement therapy and modulation of vascular function in cardiovascular disease
    • Koledova VV & Khalil RA 2007 Sex hormone replacement therapy and modulation of vascular function in cardiovascular disease. Expert Review of Cardiovascular Therapy 5 1-13.
    • (2007) Expert Review of Cardiovascular Therapy , vol.5 , pp. 1-13
    • Koledova, V.V.1    Khalil, R.A.2
  • 23
    • 67349237917 scopus 로고    scopus 로고
    • Mechanism of androgen receptor action
    • Li J & Al-Azzawi F 2009 Mechanism of androgen receptor action. Maturitas 63 142-148.
    • (2009) Maturitas , vol.63 , pp. 142-148
    • Li, J.1    Al-Azzawi, F.2
  • 25
    • 0030920365 scopus 로고    scopus 로고
    • The first 35 amino acids and fatty acylation sites determine the molecular targeting of endothelial nitric oxide synthase into the Golgi region of cells: a green fluorescent protein study
    • Liu J, Hughes TE & Sessa WC 1997 The first 35 amino acids and fatty acylation sites determine the molecular targeting of endothelial nitric oxide synthase into the Golgi region of cells: a green fluorescent protein study. Journal of Cell Biology 137 1525-1535.
    • (1997) Journal of Cell Biology , vol.137 , pp. 1525-1535
    • Liu, J.1    Hughes, T.E.2    Sessa, W.C.3
  • 27
    • 40849145707 scopus 로고    scopus 로고
    • Dehydroepiandrosterone stimulates endothelial proliferation and angiogenesis through extracellular signal regulated kinase 1/2-mediated mechanisms
    • Liu D, Iruthayanathan M, Homan L, Wang Y, Yang L, Wang Y & Dillon J 2008 Dehydroepiandrosterone stimulates endothelial proliferation and angiogenesis through extracellular signal regulated kinase 1/2-mediated mechanisms. Endocrinology 149 889-898.
    • (2008) Endocrinology , vol.149 , pp. 889-898
    • Liu, D.1    Iruthayanathan, M.2    Homan, L.3    Wang, Y.4    Yang, L.5    Wang, Y.6    Dillon, J.7
  • 29
    • 34249297914 scopus 로고    scopus 로고
    • Sex steroids and endothelial function: translating basic science to clinical practice
    • Miller VM & Mulvagh SL 2007 Sex steroids and endothelial function: translating basic science to clinical practice. Trends in Pharmacological Sciences 28 263-270.
    • (2007) Trends in Pharmacological Sciences , vol.28 , pp. 263-270
    • Miller, V.M.1    Mulvagh, S.L.2
  • 30
    • 46949109892 scopus 로고    scopus 로고
    • Vascular actions of estrogens: functional implications
    • Miller VM & Duckles SP 2008 Vascular actions of estrogens: functional implications. Pharmacological Reviews 60 210-241.
    • (2008) Pharmacological Reviews , vol.60 , pp. 210-241
    • Miller, V.M.1    Duckles, S.P.2
  • 32
    • 66949172751 scopus 로고    scopus 로고
    • Promoting mechanisms of vascular health: circulating progenitor cells, angiogenesis, and reverse cholesterol transport
    • Moreno PR, Sanz J & Fuster V 2009 Promoting mechanisms of vascular health: circulating progenitor cells, angiogenesis, and reverse cholesterol transport. Journal of the American College of Cardiology 53 2315-2323.
    • (2009) Journal of the American College of Cardiology , vol.53 , pp. 2315-2323
    • Moreno, P.R.1    Sanz, J.2    Fuster, V.3
  • 33
    • 0037133622 scopus 로고    scopus 로고
    • Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: implications in atherosclerosis
    • Mukherjee TK, Dinh H, Chaudhuri G & Nathan L 2002 Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: implications in atherosclerosis. PNAS 99 4055-4060.
    • (2002) PNAS , vol.99 , pp. 4055-4060
    • Mukherjee, T.K.1    Dinh, H.2    Chaudhuri, G.3    Nathan, L.4
  • 34
    • 33646178259 scopus 로고    scopus 로고
    • Hormone replacement therapy and the cardiovascular system lessons learned and unanswered questions
    • Ouyang P, Michos ED & Karas RH 2006 Hormone replacement therapy and the cardiovascular system lessons learned and unanswered questions. Journal of the American College of Cardiology 47 1741-1753.
    • (2006) Journal of the American College of Cardiology , vol.47 , pp. 1741-1753
    • Ouyang, P.1    Michos, E.D.2    Karas, R.H.3
  • 35
    • 77951826203 scopus 로고    scopus 로고
    • Do androgens play a beneficial role in the regulation of vascular tone? Nongenomic vascular effects of testosterone metabolites American Journal of Physiology
    • Perusquía M & Stallone JN 2010 Do androgens play a beneficial role in the regulation of vascular tone? Nongenomic vascular effects of testosterone metabolites American Journal of Physiology. Heart and Circulatory Physiology 298 H1301-H1307.
    • (2010) Heart and Circulatory Physiology , vol.298
    • Perusquía, M.1    Stallone, J.N.2
  • 37
    • 41449115538 scopus 로고    scopus 로고
    • Sex steroids and vascular responses in hypertension and aging
    • Qiao X, Mcconnell KR & Khalil RA 2008 Sex steroids and vascular responses in hypertension and aging. Gender Medicine 5 S46-S64.
    • (2008) Gender Medicine , vol.5
    • Qiao, X.1    Mcconnell, K.R.2    Khalil, R.A.3
  • 38
    • 37049005787 scopus 로고    scopus 로고
    • The direct action of estrone on vascular tissue involves genomic and non-genomic actions
    • Rauschemberger MB, Sellés J & Massheimer V 2008 The direct action of estrone on vascular tissue involves genomic and non-genomic actions. Life Sciences 82 115-123.
    • (2008) Life Sciences , vol.82 , pp. 115-123
    • Rauschemberger, M.B.1    Sellés, J.2    Massheimer, V.3
  • 39
    • 74949133887 scopus 로고    scopus 로고
    • Testosterone acts as an efficacious vasodilator in isolated in isolated human pulmonary arteries and veins: evidence for a biphasic effect at physiological and supra-physiological concentrations
    • Rowell KO, Hall J, Pugh PJ, Jones TH, Channer KS & Jones RD 2009 Testosterone acts as an efficacious vasodilator in isolated in isolated human pulmonary arteries and veins: evidence for a biphasic effect at physiological and supra-physiological concentrations. Journal of Endocrinological Investigation 32 718-773.
    • (2009) Journal of Endocrinological Investigation , vol.32 , pp. 718-773
    • Rowell, K.O.1    Hall, J.2    Pugh, P.J.3    Jones, T.H.4    Channer, K.S.5    Jones, R.D.6
  • 41
    • 15244351957 scopus 로고    scopus 로고
    • Novel action of estrone on vascular tissue: regulation of NOS and COX activity
    • Selles J, Polini N, Alvarez C &Massheimer V 2005 Novel action of estrone on vascular tissue: regulation of NOS and COX activity. Steroids 70 251-256.
    • (2005) Steroids , vol.70 , pp. 251-256
    • Selles, J.1    Polini, N.2    Alvarez, C.3    Massheimer, V.4
  • 42
    • 0042816523 scopus 로고    scopus 로고
    • Dehydroepiandrosterone modulates endothelilal nitric oxide synthesis via direct genomic and nongenomic mechanisms
    • Simoncini T, Mannella P, Fornari L, Varone G, Caruso A & Genazzani AR 2003 Dehydroepiandrosterone modulates endothelilal nitric oxide synthesis via direct genomic and nongenomic mechanisms. Endocrinology 144 3449-3455.
    • (2003) Endocrinology , vol.144 , pp. 3449-3455
    • Simoncini, T.1    Mannella, P.2    Fornari, L.3    Varone, G.4    Caruso, A.5    Genazzani, A.R.6
  • 43
    • 0036177557 scopus 로고    scopus 로고
    • Testosterone-induced vasorelaxation in the rat mesenteric arterial bed is mediated predominantly via potassium channels
    • Tep-areenan P, Kendall DA & Randall MD 2002 Testosterone-induced vasorelaxation in the rat mesenteric arterial bed is mediated predominantly via potassium channels. British Journal of Pharmacology 135 735-740.
    • (2002) British Journal of Pharmacology , vol.135 , pp. 735-740
    • Tep-areenan, P.1    Kendall, D.A.2    Randall, M.D.3
  • 44
    • 33646697351 scopus 로고    scopus 로고
    • Nitric oxide and cell proliferation
    • Villalobo A 2006 Nitric oxide and cell proliferation. FEBS Journal 273 2329-2344.
    • (2006) FEBS Journal , vol.273 , pp. 2329-2344
    • Villalobo, A.1
  • 45
    • 44949146115 scopus 로고    scopus 로고
    • Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor
    • Villar I, Hobbs A & Ahluwalia A 2008 Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor. Journal of Endocrinology 197 447-462.
    • (2008) Journal of Endocrinology , vol.197 , pp. 447-462
    • Villar, I.1    Hobbs, A.2    Ahluwalia, A.3
  • 46
    • 25444515648 scopus 로고    scopus 로고
    • Estrogen-induced contraction of coronary arteries is mediated by superoxide generated in vascular smooth muscle American Journal of Physiology
    • White RE, Han G, Dimitropoulou C, Zhu S, Miyake K, Fulton D, Dave S & Barman SA 2005 Estrogen-induced contraction of coronary arteries is mediated by superoxide generated in vascular smooth muscle. American Journal of Physiology. Heart and Circulatory Physiology 289 H1468-H1475.
    • (2005) Heart and Circulatory Physiology , vol.289
    • White, R.E.1    Han, G.2    Dimitropoulou, C.3    Zhu, S.4    Miyake, K.5    Fulton, D.6    Dave, S.7    Barman, S.A.8
  • 47
    • 4544302443 scopus 로고    scopus 로고
    • Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors
    • Williams MR, Dawood T, Ling S, Dai A, Lew R, Myles K, Funder JW, Sudhir K & Komesaroff PA 2004 Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors. Journal of Clinical Endocrinology and Metabolism 89 4708-4715.
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , pp. 4708-4715
    • Williams, M.R.1    Dawood, T.2    Ling, S.3    Dai, A.4    Lew, R.5    Myles, K.6    Funder, J.W.7    Sudhir, K.8    Komesaroff, P.A.9
  • 48
    • 77950286070 scopus 로고    scopus 로고
    • Androgen receptor-dependent activation of endothelial nitric oxide synthase in vascular endothelial cells: role of phosphatidylinositol 3-kinase/AKT pathway
    • Yu J, Akishita M, Ogawa S, Son B, Kato S, Ouchi Y & Okabe T 2010 Androgen receptor-dependent activation of endothelial nitric oxide synthase in vascular endothelial cells: role of phosphatidylinositol 3-kinase/AKT pathway. Endocrinology 151 1822-1828.
    • (2010) Endocrinology , vol.151 , pp. 1822-1828
    • Yu, J.1    Akishita, M.2    Ogawa, S.3    Son, B.4    Kato, S.5    Ouchi, Y.6    Okabe, T.7


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